Negative / Null Result ReportMedicine
Abushouk A, Layoun H, Harb SC et al. · 2024 · Journal of cardiac failure
Novel transcatheter therapies for tricuspid regurgitation (TR) appear promising, yet their applicability to an all-comer TR population remains unclear. We aimed to assess the feasibility of emerging transcatheter tricuspid therapies in a…
View details →DOI: 10.1016/j.cardfail.2024.07.014 Negative / Null Result ReportOpen accessMedicine
Chaccour C, Nicolas P, Martinho S et al. · 2025 · EClinicalMedicine
Background Endectocides are a novel vector control tool that reduce the survival and fertility of blood sucking arthropods that feed upon treated humans or animals. Ivermectin mass drug administration is under evaluation as a complementary…
View details →DOI: 10.1016/j.eclinm.2025.103632 Negative / Null Result ReportOpen accessMedicine
Antunes FTT, Gadotti VM, Zamponi GW · 2025 · Molecular brain
Alpha-bisabolol and camphene have demonstrated analgesic effects in inflammatory pain models by blocking Cav3.2 calcium channels. As the pain pathway overlaps with mechanisms for itch, and because Cav3.2 channels have been associated with…
View details →DOI: 10.1186/s13041-025-01196-9 Negative / Null Result ReportMedicine
Yang W, Ding X, Yu Y et al. · 2024 · Clinical radiology
Aims To investigate the long-term prognostic value of coronary computed tomography angiography (CCTA)-derived high-risk attributes and radiomic features of pericoronary adipose tissue (PCAT) in diabetic patients for predicting major…
View details →DOI: 10.1016/j.crad.2024.08.018 Negative / Null Result ReportMedicine
Deering TF, Reiffel JA, Solomon AJ et al. · 2023 · The American journal of cardiology
Atrial fibrillation (AF) is a potentially serious health risk, both because of its symptoms and because of its association with an increased risk for heart failure, hospitalization, thromboembolism, and death. Chapter 2 discusses selection…
View details →DOI: 10.1016/j.amjcard.2023.08.022 Negative / Null Result ReportOpen accessMedicine
Hamby M, Egleston BL, Frosch ZAK et al. · 2026 · Blood cancer journal
Plasmablastic lymphoma (PBL) is a rare, aggressive AIDS-related lymphoma observed in patients with immunosuppressed states as well as in immunocompetent individuals. We sought to determine survival outcomes, prognostic factors, and optimal…
View details →DOI: 10.1038/s41408-026-01457-3 Negative / Null Result ReportMedicine
Bhuvana J, Shivhare V, Rath S et al. · 2025 · Journal of cancer research and therapeutics
Objectives Medullary thyroid carcinoma (MTC) accounts for only about 5% of total thyroid cancers. It usually presents as an advanced disease carrying a poor prognosis than well-differentiated thyroid cancers. While the treatment of choice…
View details →DOI: 10.4103/jcrt.jcrt_1174_23 Negative / Null Result ReportOpen accessMedicine
Park SK, Chung Y, Oh CM et al. · 2026 · Gut and liver
Background/aims Studies have demonstrated that gastroesophageal reflux disease has an unfavorable effect on sleep. However, it is largely unknown whether erosive esophagitis (EE) is associated with sleep issues. Methods Study participants…
View details →DOI: 10.5009/gnl250045 Negative / Null Result ReportOpen accessMedicine
Cheng CM, Tsai MJ, Tseng CC et al. · 2026 · Journal of the Chinese Medical Association : JCMA
Agitation is a frequently occurring and challenging neuropsychiatric symptom of Alzheimer's disease (AD) that substantially affects quality of life, caregiver burden, and healthcare utilization. Nonpharmacological interventions, especially…
View details →DOI: 10.1097/jcma.0000000000001342 Negative / Null Result ReportMedicine
Stitt GA, Hall MW, Diliberto MA et al. · 2025 · The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
Objectives Primary objective: to quantify tocilizumab (TCZ) use in pediatric inpatients. Secondary objectives: to explore safety and clinical outcomes. Methods This retrospective cohort study took place in a free-standing, 564-bed…
View details →DOI: 10.5863/jppt-24-00130 Negative / Null Result ReportOpen accessMedicine
Kern DM, Bohn J, Maher MP et al. · 2026 · BMJ open
Objective To use best practices in pharmacoepidemiology to assess the association between new use of brain-penetrant calcium channel blockers (BP-CCBs) compared with use of non-brain-penetrant CCBs (NP-CCBs) and the incidence of…
View details →DOI: 10.1136/bmjopen-2025-100282 Negative / Null Result ReportMedicine
Deodato M, Melcher D · 2024 · Journal of cognitive neuroscience
The brain organizes the continuous flow of sensory input by parsing it into discrete events. In the case of two flashes separated by a brief ISI, for example, perception may be of a single flash or two distinct flashes, depending on the…
View details →DOI: 10.1162/jocn_a_01993 Negative / Null Result ReportOpen accessMedicine
Ambasta A, Grenet G, Otte J et al. · 2025 · African journal of primary health care & family medicine
Thyroid hormones regulate essential metabolic processes and development. The hypothalamic-pituitary-thyroid axis regulates hormone production, with thyroid-stimulating hormone (TSH) levels being a key indicator of thyroid function in…
View details →DOI: 10.4102/phcfm.v17i1.5043 Negative / Null Result ReportOpen accessMedicine
Neul JL · 2024 · The Journal of clinical investigation
Fragile X syndrome (FXS), the most common inherited cause of intellectual disability and the single-gene cause of autism, is caused by decreased expression of the fragile X messenger ribonucleoprotein protein (FMRP), a ribosomal-associated…
View details →DOI: 10.1172/jci175036 Negative / Null Result Report
SUN X, GODJE ISG, HU H et al. · 2024 · Preprint
Despite breakthroughs in care and treatment, the consequences of a subarachnoid hemorrhage (SAH) are still associated with morbidity and mortality. Early brain injury is still a major source of clinical deterioration in people with SAH.…
View details →DOI: 10.22541/au.170669249.92768577/v1 Negative / Null Result ReportMedicine
Vicario-Feliciano R, Zil-E-Ali A, Aziz F · 2025 · Annals of vascular surgery
Introduction Predictors of sac behavior after endovascular aortic aneurysm repair (EVAR) and the impact of sac behavior on long-term survival are not well known. There are limited multicenter trials studying the impact of beta blockers…
View details →DOI: 10.1016/j.avsg.2024.07.104 Negative / Null Result ReportOpen accessMedicine
Maines E, Franceschi R, Candia FD et al. · 2025 · Diabetes/metabolism research and reviews
Definitive prevention for type 1 diabetes (T1D) is not yet available, but we are now entering a new era where disease-modifying therapies are becoming available in T1D to halt disease progression. In this review, we present up-to-date…
View details →DOI: 10.1002/dmrr.70101 Negative / Null Result ReportOpen accessMedicine
Reboul A, Claidière N, Dautriche I et al. · 2025 · PloS one
This study investigates whether baboons are capable of semantic compositionality, specifically, whether they can apply compositional rules to new situations (generalization). In language, semantic compositionality is linked to…
View details →DOI: 10.1371/journal.pone.0334726 Negative / Null Result Report
Chen Y, He M, Zhao S et al. · 2024 · Preprint
Objective: To investigate the clinical value of adding on Jin-gu-lian Capsule (JGL) in rheumatoid arthritis (RA) treatment on disease activity and quality of life (QoL) by a real world study (RWS). Methods A RWS was conducted to compare…
View details →DOI: 10.21203/rs.3.rs-4075741/v1 Negative / Null Result Report
Ghosh R · 2024 · Preprint
Abstract Background: Consolidation therapy with high dose cytarabine (HIDAC) for Acute Myeloid Leukemia (AML)is associated with significant neutropenia , resultant infections and associated morbidities. In this prospective study on de novo…
View details →DOI: 10.21203/rs.3.rs-3713643/v1 Negative / Null Result ReportOpen accessMedicine
Baker JF · 2026 · Hip & pelvis
Purpose Surgeons are both interested in the relationship between spinopelvic parameters and acetabular orientation since concomitant diseases of the spine and hip are common. Spondylolysis of L5 is common in 4% to 8% of the population. L5…
View details →DOI: 10.5371/hp.2026.38.1.27 Negative / Null Result ReportOpen accessMedicine
Könemann H, Güler-Eren S, Ellermann C et al. · 2024 · Current heart failure reports
Purpose of review Arrhythmias are common in patients with heart failure (HF) and are associated with a significant risk of mortality and morbidity. Optimal antiarrhythmic treatment is therefore essential. Here, we review current approaches…
View details →DOI: 10.1007/s11897-023-00642-w Negative / Null Result ReportOpen accessMedicine
Zafarani F, Soleimani Mehranjani M, Ghaffari F et al. · 2024 · International journal of fertility & sterility
Background This study aimed to determine the alteration of endometrial expression levels of HOXA9/HOXA10/ HOXA11/HOXD10 genes and HOX transcript antisense intergenic RNA (HOTAIR) in mid-luteal phase endometrium in patients with…
View details →DOI: 10.22074/ijfs.2024.2026081.1655 Negative / Null Result ReportOpen accessMedicine
Gandhi A, Parhizgar A · 2025 · Frontiers in endocrinology
Initially developed for type 2 diabetes and obesity, glucagon-like peptide-1 receptor agonists (GLP-1RAs) are now emerging as promising candidates for modifying the course of neurodegenerative diseases. This potential stems from the…
View details →DOI: 10.3389/fendo.2025.1708565 Negative / Null Result ReportMedicine
Aragón-Sánchez J, Víquez-Molina G, López-Valverde ME et al. · 2023 · Diabetic medicine : a journal of the British Diabetic Association
Aims We hypothesize that microbiology- and pathology-confirmed positive bone margins after the resection of diabetes-related foot osteomyelitis are associated with worse outcomes. Methods We conducted a prospective study consisting of a…
View details →DOI: 10.1111/dme.15162 Negative / Null Result ReportMedicine
Ahmed N, Russo L, Kuo YH · 2024 · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Objectives To compare levetiracetam and phenytoin as prophylaxis for the short-term development of status epilepticus (SE) during care of pediatric patients with acute severe traumatic brain injury (TBI). Design Nonprespecified secondary…
View details →DOI: 10.1097/pcc.0000000000003526 Negative / Null Result ReportOpen accessMedicine
Shefner JM, Cudkowicz ME, Genge A et al. · 2025 · JAMA neurology
Importance Treatment options for amyotrophic lateral sclerosis (ALS) remain suboptimal. Results from a phase 2 study of reldesemtiv in ALS suggested that it may slow disease progression. Objective To assess the effect of reldesemtiv vs…
View details →DOI: 10.1001/jamaneurol.2025.0241 Negative / Null Result ReportOpen accessMedicine
Apivatgaroon A, Sukkarnkosol S, Pukrittayakamee NC et al. · 2025 · JSES international
Background Suspension stabilization is a commonly used surgical method for acute acromioclavicular (AC) joint dislocation. However, a failure rate of around 26% caused various emerging surgical techniques and recommendations. We aimed to…
View details →DOI: 10.1016/j.jseint.2024.12.020 Negative / Null Result ReportMedicine
Rannikko EH, Pajula S, Suominen SH et al. · 2025 · Plastic and reconstructive surgery
Background Breast cancer-related lymphedema is a common complication lacking medical treatment. Lymfactin is an adenovirus type 5-based gene therapy and prolymphangiogenic growth factor vector that induces vascular endothelial growth…
View details →DOI: 10.1097/prs.0000000000011675 Negative / Null Result ReportOpen accessMedicine
Kim S, Shin MJ, Krauss RM · 2025 · Current atherosclerosis reports
Purpose of review This paper reviews the effects of major macronutrients and specific dietary interventions on atherogenic dyslipidemia, a common trait characterized by increased concentrations of triglyceride-rich and small, dense LDL…
View details →DOI: 10.1007/s11883-025-01335-6 