A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19847 results in Negative / Null Result Report · page 299 of 662
Parveen A, Jatoi R, Haya A et al. · 2026 · Cureus
Background and aim Postpartum depression (PPD) is a mental health condition that adversely affects both maternal and infant well-being. Kangaroo Mother Care (KMC), involving skin-to-skin contact and exclusive breastfeeding, has shown…
Izquierdo JA, Kerbel J, Apodaca G et al. · 2026 · Cureus
Background Intraoperative periprosthetic femoral fracture is an uncommon but clinically significant complication of total hip arthroplasty (THA) that may compromise implant stability and increase the risk of early revision surgery. Several…
Wang Y, Zhang Y, Lan Y · 2026 · Scientific reports
The mental health of young people serves as a social barometer, reflecting societal conditions. However, the relationship between social inequality and youth mental health remains a contested issue. This study uses data from the China…
Chen Z, Zhang L, Liang Y et al. · 2026 · Digestive diseases and sciences
Background and aims Post-ESD esophageal stricture remains a major complication despite steroid prophylaxis. Temporary stent placement has been proposed as an adjunctive strategy in high-risk cases, yet its independent effect remains…
Yubaitsa CN, Gani KS, Mitchel M et al. · 2026 · Cureus
Background Musculoskeletal problems in the elderly pose a significant challenge for healthcare providers, as they constitute a vulnerable group. Fractures are often undetected, leading to a reduced quality of life due to increased…
Bastian MB, Kyriakou I, Rosar F et al. · 2026 · The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...
Background Papillary thyroid carcinoma (PTC) with a BRAFV600E mutation is linked to more aggressive tumor characteristics, as well as a higher likelihood of recurrence and disease-specific mortality. This study aimed to investigate the…
Park JE · 2026 · Korean journal of community nutrition
Objectives This study aimed to evaluate the relationship between oxidative balance score (OBS), a metric indicating an individual's oxidative balance status, and the number of teeth in a sample of Korean adults. Methods This…
Hacıvelioğlu D, Turan Tercan A, Tuna Oran N · 2026 · BMC public health
This study examined xenophobia and empathic tendency among 724 midwifery students from different regions of Turkey. Data were collected online using the Student Information Form, the Empathic Tendency Scale, and the Xenophobia Scale, and…
Skowron AT, Childers K, Rose CM et al. · 2026 · The Prostate
Purpose Germline genetic testing in patients with advanced prostate cancer (PCa) is underutilized and hypothesized to be impacted by socioeconomic and demographic factors. This single institution, retrospective study assessed the…
Pisanu C, Squassina A, Perera-Bel J et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Treatment-resistant depression (TRD) is a major clinical challenge in the management of major depressive disorder (MDD). While pharmacogenetics has been suggested to be clinically useful in guiding…
Madsen TE, Raker CA, Pavlovic JM et al. · 2026 · Neurology
Background and objectives Migraine is a known risk factor for stroke in women of reproductive age, although its relationship with stroke among postmenopausal women remains unclear. We assessed the association between migraine history and…
Healey J, Singh M, Richards C et al. · 2026 · BMC medicine
Background Among women in the UK, over 186,000 new cancer diagnoses and around 78,000 cancer deaths occurred annually from 2017 to 2019. Evidence suggests that pregnancy complications are linked to mortality and morbidity risks in later…
Laowong O, Sonsuwan N, Chaiworawitkul M · 2026 · Sleep & breathing = Schlaf & Atmung
PURPOSE: This study investigated anatomical factors associated with obstructive sleep apnea (OSA) in children with unilateral cleft lip and palate (UCLP), focusing on tongue, airway, and hyoid height, using cone-beam computed tomography…
Anees R, Chaudhary MAG, Fatima SK · 2026 · Scientific reports
Facial aesthetics depends on the harmony between facial features and dental morphology, specifically the link between face shape and maxillary central incisor form. Classical theories propose that tooth form corresponds to face outline;…
Alibrahim T, Johnston Y · 2026 · Journal of gerontological nursing
Purpose To examine fall-related medications and fall risk as predictors of fall-related hospitalizations among a cohort of community-dwelling older adults in the southern tier of New York State. Method Participants comprised 8,499 patients…
Pande S, Dakhore S, Arora D et al. · 2026 · Cureus
Background Breast cancer is the most common malignancy among women worldwide and remains a leading cause of cancer-related mortality. In India, delayed presentation and limited access to organised screening programmes contribute to poorer…
Vilsmeier J, Büchele G, Rehm M et al. · 2026 · BMC medical research methodology
Background In the EvaCoM project, a retrospective cohort study of Germany-wide health insurance data of 29607 geriatric patients with fractures, the use of different time scales led to contradicting estimates in the Cox proportional…
Davis AE, Su Y, Dallas R et al. · 2026 · Emerging microbes & infections
Human astroviruses are a common cause of viral gastroenteritis and are often underdiagnosed. While infections are typically mild or asymptomatic in immunocompetent hosts, astrovirus can cause prolonged and severe disease in…
Mittal A, Malhotra K, Panwar V et al. · 2026 · Urology research & practice
Objective: This retrospective cross-sectional analytical study evaluated the clinicopathological associations of programmed death ligand 1 (PD-L1) and human epidermal growth factor receptor 2 (HER2/neu) expression in 250 patients with…
Bahta H, Kahsay A, Mewcha G · 2026 · Preprint
This study aims to assess beekeeper’s perceptions of honeybee colony behavior, climate related challenges and hive productivity in Tigray. The research design was used a mixed-approach method with multi-stage sampling techniques to select…
Qiao X, Wang Y, Tian Z et al. · 2026 · Frontiers in psychiatry
Aim To explore the symptom distress and quality of life status of patients with Chronic Kidney Disease (CKD) Stage 5 undergoing hemodialysis in China, and their correlation. Methods The Dialysis Symptom Index (DSI) and the Kidney Disease…
Özen GY, Özen AK, Bilge NH · 2026 · Diagnostics (Basel, Switzerland)
Background: The anatomical position of the hyoid bone and the morphological characteristics of the soft palate play a key role in upper airway patency, craniofacial balance, and the coordination of functional structures. These features may…
Clarke G, Shuweihdi F, Relton SD et al. · 2026 · The British journal of general practice : the journal of the Royal College of General Practitioners
Background Primary palliative care is symptom support and care for people with life-limiting illnesses incorporated within standard primary care. Early identification of needs is best practice. There is limited research concerning…
Hallab A · 2026 · Thyroid research
Thyroid hormones modulate brain structures during neurogenesis and impact cognition and emotions during the lifetime. Hypothyroidism is commonly associated with lower gray matter volume. Fewer studies, however, highlighted significant…
Clarke B, Sajjad A, Moodie N et al. · 2026 · Preprint
The topics and questions that social and personality psychologists study attract a great deal of public interest. The level of evidence required to make an application claim should be high, in our opinion, to avoid misapplying evidence…
Ojo EO, Xie R, Ng BP et al. · 2026 · Research in gerontological nursing
Purpose The current study aimed to examine the association between cognitive function, fear of falling, and physical activity and assess the moderating effect of physical activity on the association between cognitive function and fear of…
Dornelas R, Marins I, Rodrigues TS et al. · 2025 · Journal of voice : official journal of the Voice Foundation
Objective To analyze the auditory perception of Korean pop (K-pop) singers' voices to identify vocal characteristics associated with gender neutrality. Study design This is a cross-sectional observational study. Methods The inclusion…
Sugimoto K, Minami T, Nukaya T et al. · 2025 · Cancer diagnosis & prognosis
Background/aim Immune checkpoint inhibitors (ICIs) have improved survival in metastatic renal cell carcinoma (mRCC), with nivolumab (NIVO) plus ipilimumab (IPI) showing benefits in intermediate- and poor-risk patients. Despite first-line…
Matouskova L, Kralova R, Parobkova E et al. · 2026 · Andrology
Background Despite robust data showing strong potential to improve diagnosis and disease monitoring in testicular germ cell tumors (TGCTs), miR-371a-3p testing has not yet been implemented in routine clinical practice. Cell-free DNA…
Sakulsriprasert P, Bunprajun T, Hengsomboon N et al. · 2026 · Scientific reports
This study evaluated floor and ceiling (F/C) effects within the Tampa Scale for Kinesiophobia (TSK) and examined item-level correlations with total TSK scores and pain intensity in individuals with knee osteoarthritis (KOA). A…