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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19843 results in Negative / Null Result Report · page 294 of 662

Negative / Null Result ReportMedicine

Multi-perspective spatial memory representation in the presence of others.

Li J, Wang Q, Xie N et al. · 2026 · Cognitive processing

In order to better adapt to spatial environments, individuals often establish a spatial frame of reference system to represent objects and their positions within a scene. This study utilized a partial scene recognition paradigm across…

View details →DOI: 10.1007/s10339-025-01327-z
Negative / Null Result ReportMedicine

Exploring fMRI-neurofeedback to reduce craving-related brain activity in people with cannabis use disorder: A feasibility study.

Murphy E, Poudel G, Dakhili AH et al. · 2026 · Addictive behaviors

Introduction Cannabis Use Disorder (CUD) can come with intense cravings, which can trigger compulsive use/relapse, underscored by anterior cingulate cortex (ACC) hyperactivity during cannabis cue-reactivity functional neuroimaging (fMRI)…

View details →DOI: 10.1016/j.addbeh.2026.108741
Negative / Null Result ReportMedicine

Treatment in Public Centers for Adult Jewish Women Survivors of Childhood Sexual Abuse in Israel: Abuse Characteristics, Psychiatric Profiles, and One-Year Treatment Outcomes.

Lev-Ari L, Mintz Malchi K, Ludmir E et al. · 2026 · Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)

Background Childhood sexual abuse (CSA) is associated with significant psychiatric morbidity and has been reported at notable rates among Jewish Israeli women. Yet data regarding abuse characteristics, psychiatric history and longitudinal…

View details →DOI: 10.1080/15299732.2026.2648314
Negative / Null Result ReportMedicine

Mavacamten Versus Alcohol Septal Ablation in Obstructive Hypertrophic Cardiomyopathy: An Echocardiography-Derived Pressure-Volume Analysis.

Reil JC, Sequeira V, Coppée C et al. · 2026 · Circulation. Heart failure

Background Obstructive hypertrophic cardiomyopathy (oHCM) is characterized by left ventricular (LV) outflow tract obstruction, which increases afterload and chronically activates the Anrep response, a compensatory (afterload-driven) state…

View details →DOI: 10.1161/circheartfailure.125.013392
Negative / Null Result ReportOpen accessMedicine

Brief intervention for inappropriate z-hypnotics use in older adults: a before and after intervention study in primary care.

Siddiqui TG, Simonsen THB, Lie Selle M et al. · 2026 · Scandinavian journal of primary health care

Background Z-hypnotics are commonly prescribed for insomnia, but their use in older adults is associated with an increased risk of adverse events. Aim We examined the long-term effect of brief intervention (BI) for inappropriate z-hypnotic…

View details →DOI: 10.1080/02813432.2026.2660168
Negative / Null Result ReportMedicine

Introduction of a dashboard visualizing outcome information during healthcare visits in Chronic Kidney Disease - An evaluation study.

van der Horst DEM, van Uden-Kraan CF, Stiggelbout AM et al. · 2026 · Patient education and counseling

Objective Effective patient-clinician communication is essential in chronic kidney disease (CKD) to support treatment adherence and slow down disease progression. In this proof-of-concept study we evaluated the effects of a CKD dashboard,…

View details →DOI: 10.1016/j.pec.2026.109629
Negative / Null Result ReportMedicine

Repeated Melatonin Implant Improves Testicular Volume, Testicular Blood Flow, Estradiol, Antioxidant Capacity, and Nitric Oxide Levels in Post-Pubertal Camels Under Heat Stress Conditions.

Abdelnaby EA, Alhaider AK, Emam IA · 2026 · Reproduction in domestic animals = Zuchthygiene

This current work aimed to determine the impacts of melatonin implants on testicular artery blood flow and Doppler indices, in relation to hormonal profile in post-pubertal camels (Camelus dromedaries) under heat stress and non-breeding…

View details →DOI: 10.1111/rda.70180
Negative / Null Result ReportMedicine

Effect of Vericiguat on Pulmonary Artery Pressures in Patients With Heart Failure: Real-World Insights From Pressure Sensor Monitoring.

Elad B, Lotan D, Richter I et al. · 2026 · Journal of cardiovascular pharmacology

Abstract Vericiguat improves outcomes in heart failure (HF) by promoting vasodilation of the systemic and pulmonary arterial beds. Little is known about its impact on pulmonary artery pressure (PAP). We aimed to study this effect using…

View details →DOI: 10.1097/fjc.0000000000001761
Negative / Null Result ReportOpen accessMedicine

Effect of an Eight-Week Breathing Exercise Program on the Respiratory Function and Craniovertebral Angle in Dental Students: A Pre-test and Post-test Quasi-experimental Study.

Hafez E, Ashraf E, Saeed S et al. · 2026 · Cureus

Introduction Dental training requires prolonged static and forward-leaning working positions that may contribute to forward head posture. Forward head posture can be quantified using the craniovertebral angle (CVA) and may be associated…

View details →DOI: 10.7759/cureus.101118
Negative / Null Result ReportOpen accessMedicine

Acute effects of continuous and interval cycling on salivary SIgA and anti-microbial peptide secretions: a randomized crossover trial.

Ito R, Uchida M, Fujie S et al. · 2026 · European journal of applied physiology

Purpose This study aimed to examine the acute effects of continuous and interval cycling on salivary secretory immunoglobulin A (SIgA) and anti-microbial peptides. Methods In a randomized crossover trial, 12 healthy young untrained men (22…

View details →DOI: 10.1007/s00421-025-05937-5
Negative / Null Result ReportMedicine

Remote monitoring contribution to the continuation of CPAP treatment in the long term: which gain and for whom? A cohort analysis.

Bayle JY, Onen F, Onen SH · 2025 · Sleep & breathing = Schlaf & Atmung

PURPOSE: The impact of remote monitoring (RM) on the likelihood of continuing CPAP therapy in apneic patients remains unknown in the long term and was addressed by a comparative cohort analysis. METHODS: The probability of continuing CPAP…

View details →DOI: 10.1007/s11325-025-03558-y
Negative / Null Result ReportMedicine

Adding free leucine to a balanced essential amino acid mixture suppresses intracellular transamination of isoleucine and valine in healthy older adults.

Knezek SB, Engelen MPKJ, Coyle KS et al. · 2026 · Clinical nutrition (Edinburgh, Scotland)

Background Adding leucine (LEU) to protein meals enhances protein anabolism, but excess LEU reduces valine (VAL) and isoleucine (ILE) plasma concentrations. We examined in older adults whether additional LEU added to an essential amino…

View details →DOI: 10.1016/j.clnu.2026.106659
Negative / Null Result ReportMedicine

Differential astrocyte activation by Taenia solium antigens: Specific induction of IL-10 and IL-1β by Excretory/Secretory (ES) products.

Gonzales K, Condori J, Fernández G et al. · 2026 · Immunobiology

Background Neurocysticercosis (NCC) is a parasitic infection of the central nervous system (CNS) caused by the larval form of Taenia solium. This disease provokes an inflammatory response that intensifies when the parasite dies. This study…

View details →DOI: 10.1016/j.imbio.2026.153162
Negative / Null Result ReportMedicine

Zinc deficiency is associated with erythropoietin-stimulating agents hyporesponsive anemia in peritoneal dialysis patients: a cross-sectional study.

Kuwahara F, Harada K, Nagata M et al. · 2026 · Clinical and experimental nephrology

Background Zinc deficiency is widely recognized as a cause of anemia, but no studies have clarified the impact of zinc deficiency on achieving target hemoglobin levels in patients undergoing peritoneal dialysis (PD) and receiving high-dose…

View details →DOI: 10.1007/s10157-026-02816-x
Negative / Null Result ReportMedicine

Risk factors for asseptic loosening after revision total knee replacement (rTKR): a component-specific analysis of femoral and tibial reconstruction.

Souto CS, Pereira F, Carvalho A et al. · 2026 · The Knee

Background Revision total knee arthroplasty (rTKA) remains a technically demanding procedure, with re-revision representing a major clinical challenge. The role of reconstruction strategies, particularly the use of augments and metaphyseal…

View details →DOI: 10.1016/j.knee.2026.104528
Negative / Null Result ReportMedicine

Similar Outcomes in Proximal Humerus Fractures Treated With Conventus Intramedullary Cage Device and Open Reduction Internal Fixation.

Kurkowski SC, Taleghani ER, McMillan P et al. · 2026 · Journal of orthopaedic trauma

Objectives To compare clinical outcomes between open reduction and internal fixation (ORIF) with or without Conventus intramedullary cage (CC) for proximal humerus fractures. Methods Design Retrospective cohort study. Setting Level 1…

View details →DOI: 10.1097/bot.0000000000003161
Negative / Null Result ReportMedicine

A comparative experimental study on the impact of radiotherapy dose rate and melatonin pretreatment in tongue and esophageal tissues.

Hacımustafaoğlu F, Aras S, Çaykara Peran B et al. · 2026 · International journal of radiation biology

Aim This study aimed to investigate the differential biological responses in tongue and esophageal tissues induced by flattening filter (FF) and flattening filter-free (FFF) beams at varying dose rates, and to assess the radioprotective…

View details →DOI: 10.1080/09553002.2026.2669157
Negative / Null Result ReportMedicine

Art v 3 sensitization is associated with increased immunological complexity but not clinical severity in lipid transfer protein syndrome.

Carbonell Martínez A · 2026 · European annals of allergy and clinical immunology

Summary Background. Lipid transfer protein (LTP)-mediated food allergy represents one of the most severe and heterogeneous forms of IgE-mediated food allergy in Mediterranean populations. Although Pru p 3 is the main marker of LTP…

View details →DOI: 10.23822/eurannaci.1764-1489.442
Negative / Null Result ReportMedicine

Surface Texture of Taste Carriers Modulates Bitter Taste Identification.

Brothánková P, Faitlová H, Sitina M et al. · 2026 · ORL; journal for oto-rhino-laryngology and its related specialties

Aim The aim of this study was to assess the relationship between texture and the correct identification of gustatory stimuli (sweet, salty, bitter, and sour) in both healthy participants and patients with taste disorders. Patients and…

View details →DOI: 10.1159/000553068
Negative / Null Result ReportMedicine

Fostering a Reflecting Processing of the Academic Crisis: The Effectiveness of Group Counselling for Underachieving University Students.

Esposito G, Passeggia R, Cannata A et al. · 2026 · Healthcare (Basel, Switzerland)

Background: University counselling services provide essential support for students navigating critical academic phases. These services have proven to be successful in promoting long-term psychological well-being and student retention.…

View details →DOI: 10.3390/healthcare14121776
Negative / Null Result ReportMedicine

AI literacy and digital psychological states: social-behavioral implications for FOMO and NOMOPHOBIA over time (2019-2025).

Sezgin ME, Kaya NB, Basarmak U et al. · 2026 · BMC psychology

Background AI literacy has become increasingly relevant in digitally mediated environments, yet its relationship with fear of missing out (FOMO) and nomophobia remains underexplored. Method The study used an exploratory design to examine…

View details →DOI: 10.1186/s40359-026-05001-7
Negative / Null Result ReportMedicine

Optimal Site of Tactile Stimulation during Initial Steps of Neonatal Resuscitation: A Three-Arm Randomized Controlled Trial.

Kolachena V, Priyadarshi M, Singh P et al. · 2026 · Resuscitation

The optimum site of tactile stimulation (TS) during initial steps of neonatal resuscitation in the delivery room (DR) is not well-established. To compare the impact of three different sites of TS (back rub, trunk rub, and sole rub) on…

View details →DOI: 10.1016/j.resuscitation.2026.111190