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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19843 results in Negative / Null Result Report · page 293 of 662

Negative / Null Result ReportMedicine

Age, Intersectional Discrimination, and Health in Black Transgender Women.

Grant S, Goldberg E, Gadipudi A et al. · 2025 · Journal of racial and ethnic health disparities

Black transgender women report high levels of discrimination, which is associated with poor health outcomes. Some evidence suggests that intersectional discrimination-that is, interacting forms of marginalization related to one's real or…

View details →DOI: 10.1007/s40615-025-02710-4
Negative / Null Result ReportMedicine

Does the Perth Alexithymia Questionnaire Offer a Multidimensional Measurement of the Alexithymia Construct?

Bagby RM, Mortezaei A, McIntyre C et al. · 2026 · Journal of personality assessment

The Perth Alexithymia Questionnaire (PAQ) was developed to assess alexithymia as a multidimensional construct consistent with the attention-appraisal model. This study evaluated the hierarchical structure of the PAQ using Goldberg's…

View details →DOI: 10.1080/00223891.2025.2559701
Negative / Null Result ReportMedicine

The psychometric properties of the working memory questionnaire in a South African young adult sample.

Ferreira-Correia A, Mnisi N, Harwood K et al. · 2025 · Applied neuropsychology. Adult

The Working Memory Questionnaire (WMQ) was developed to assess everyday difficulties associated with working memory (WM) impairments. This study evaluated the psychometric properties of the WMQ within a South African context. A…

View details →DOI: 10.1080/23279095.2025.2556922
Negative / Null Result ReportOpen accessMedicine

Understanding how a tap on/tap off system supports clinical work in an emergency department: a qualitative study.

Baysari M, Stanceski K, Bamgboje-Ayodele A et al. · 2026 · BMC medical informatics and decision making

Background Single sign-on (SSO), tap-on-tap-off (TOTO) and virtual desktops (VD) are increasingly being used in hospitals to reduce the burden and risks of password management, but we know little about how these systems are used in…

View details →DOI: 10.1186/s12911-026-03424-1
Negative / Null Result ReportMedicine

Associations of physical activity and sedentary behaviors with mortality: An observational analysis and Mendelian randomization study.

Han M, Qu Y, Zeng M et al. · 2026 · Geriatric nursing (New York, N.Y.)

Background To investigate the associations of physical activity (PA) and sedentary behavior (SB) with the risk of mortality using observational and Mendelian randomization (MR) designs. Methods In a prospective cohort study based on UK…

View details →DOI: 10.1016/j.gerinurse.2026.103834
Negative / Null Result ReportMedicine

Changes in Peri-Implant Soft Tissue Dimensions Following Soft Tissue Contour Augmentation: A 3-Year Follow-Up of a Multi-Center RCT.

Jepsen K, Jepsen S, Hämmerle CHF et al. · 2026 · Clinical oral implants research

Aim To assess 3-year changes of peri-implant tissues following previous soft tissue (volume) augmentation (STA) with a volume-stable collagen matrix (VCMX) or connective tissue (SCTG) at single-implant restorations. Material and methods In…

View details →DOI: 10.1111/clr.70078
Negative / Null Result ReportMedicine

Parental care liberates juvenile growth: a common-garden test of the evolutionary benefits of care.

Eggert AK, Prang MA, Capodeanu-Nägler A et al. · 2026 · Evolution; international journal of organic evolution

Effects on juvenile growth have long been considered an important benefit of parental care, but they have rarely been tested empirically. Protection and feeding by parents might accelerate offspring growth by allowing offspring to allocate…

View details →DOI: 10.1093/evolut/qpaf223
Negative / Null Result ReportOpen accessMedicine

The association between weekend catch-up sleep and obesity in U.S. adults: A cross-sectional analysis of NHANES 2017-2020.

Zeng J, Huang D, Zhu M et al. · 2025 · Medicine

Weekend catch-up sleep (WCS) is a behavioral strategy employed to compensate for weekday sleep loss and has been reported to be associated with various metabolic outcomes. However, its association with obesity remains controversial. This…

View details →DOI: 10.1097/md.0000000000044670
Negative / Null Result ReportMedicine

<i>N</i>-glycans on SLC26A3 do not significantly alter plasma membrane or lipid raft trafficking, but appear to stabilize interdomain contacts to stimulate transport.

Achilles S, Tomczak JN, Baumann FS et al. · 2025 · American journal of physiology. Gastrointestinal and liver physiology

DRA (Downregulated in adenoma, SLC26A3) is a major apical intestinal Cl - /HCO 3 - exchanger, which is expressed in complex and hybrid N -glycosylated forms. Although the importance of N -glycosylation is evident from the significantly…

View details →DOI: 10.1152/ajpgi.00362.2024
Negative / Null Result ReportMedicine

Effects of a Secondary Cognitive Task on Psychological and Stretch Performance.

Kostrna J, Astudillo A, Perez E · 2025 · Research quarterly for exercise and sport

Extensive research supports the positive effects of stretching on joint flexibility. During stretching, an individual's perceptions of stretch-related discomfort and pain negatively influence affective response. This study examined the…

View details →DOI: 10.1080/02701367.2025.2496765
Negative / Null Result ReportOpen accessMedicine

Piperacillin-tazobactam-associated thrombocytopenia with negative antiplatelet antibody testing: a case report and literature review.

Tian P, Fan M, Huang C · 2026 · Frontiers in medicine

Background Piperacillin-tazobactam is a widely used antibiotic. Although rare, thrombocytopenia related to piperacillin-tazobactam can be clinically significant. Drug-induced immune thrombocytopenia (DIIT) is difficult to distinguish from…

View details →DOI: 10.3389/fmed.2026.1775491
Negative / Null Result ReportMedicine

Body temperature and time perception in morning and evening types.

Erdoğan Ş, Tavat BC · 2025 · Physiology & behavior

Previous studies have suggested that time perception fluctuates throughout the day in relation to daily fluctuations of body temperature, and that there is a negative relationship between body temperature and time perception. The aim of…

View details →DOI: 10.1016/j.physbeh.2025.114943
Negative / Null Result Report

Inflammatory cytokines promote interferon regulatory factor (IRF) transcriptional activity in human pulmonary epithelial cells through the induction of IRF1 by nuclear factor-κB

Necker-Brown A, Mostafa MM, Georgescu A et al. · 2025 · Preprint

Transcription factors of the interferon regulatory factor (IRF) family play key roles during viral and bacterial infections. However, IRF regulation by inflammatory cytokines, including interleukin (IL)-1β and tumor necrosis factor (TNF)…

View details →DOI: 10.1101/2025.07.24.665057
Negative / Null Result ReportMedicine

Effect of Radial Lengthening on the Stability of the Distal Radioulnar Joint: A Biomechanical Cadaveric Study.

Yin CY, Vilai P, Thoreson AR et al. · 2026 · The Journal of hand surgery

Purpose Radial lengthening has been clinically proposed as an alternative treatment for distal radioulnar joint (DRUJ) instability associated with distal radius fractures based on the hypothesis that it functions in a manner similar to…

View details →DOI: 10.1016/j.jhsa.2025.06.013
Negative / Null Result ReportMedicine

Three-dimensional Reservoir Modelling and Quantitative Microbial Risk Assessment of Recreational Access to a Drinking Water Reservoir.

Cinque K, Deere D, Veal C et al. · 2025 · Environmental management

The major drinking water reservoirs and catchments supplying many of Australia's capital cities have been protected from significant levels of public access since their construction (up to 140 years ago). In addition to the primary…

View details →DOI: 10.1007/s00267-025-02203-4
Negative / Null Result ReportMedicine

Comparison of Asynchronous Telepsychiatry vs Synchronous Telepsychiatry (CATELEST) in Skilled Nursing Facilities: A Randomized Controlled Noninferiority Clinical Trial.

Xiong GL, Iosif AM, Gonzalez AD et al. · 2025 · Journal of the American Medical Directors Association

Objective Comparison of asynchronous telepsychiatry (ATP) with traditional synchronous telepsychiatry (STP) in skilled nursing facilities (SNFs) in California, United States. Design Patient-level randomized, controlled noninferiority…

View details →DOI: 10.1016/j.jamda.2025.105753
Negative / Null Result ReportMedicine

Neurocognitive passport: A novel feedback tool for pediatric patients with sickle cell disease.

Karst J, Miller M, Simpson P et al. · 2026 · Journal of child health care : for professionals working with children in the hospital and community

Sickle Cell Disease (SCD) is associated with neurocognitive impairment, and routine cognitive and academic screening is recommended. Traditional reports following testing are often not health literate, limiting the usefulness of…

View details →DOI: 10.1177/13674935251326787
Negative / Null Result ReportMedicine

Colourful Urban Birds: Bird Species Successful in Urban Environments Have More Elaborate Colours and Less Brown.

Ibáñez-Álamo JD, Delhey K, Izquierdo L et al. · 2025 · Ecology letters

Rapidly expanding urbanisation presents significant challenges to wildlife. Consequently, many studies have investigated the impact of urbanisation on diverse organisms. However, despite the ecological relevance of animal colouration, its…

View details →DOI: 10.1111/ele.70106
Negative / Null Result ReportOpen accessMedicine

Ocular Findings in Women with Cervical HPV Positivity and Cervical Dysplasia Undergoing Loop Electrosurgical Excision Procedure: A Prospective Cross-Sectional Study.

Vural NA, Mergen B, Güler S et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : To evaluate ocular findings in women with cervical HPV positivity undergoing loop electrosurgical excision procedure (LEEP) for cervical dysplasia and to assess conjunctival/eyelid papilloma and other ocular…

View details →DOI: 10.3390/medicina62050969
Negative / Null Result ReportMedicine

Impact of preoperative use of biologics on 30-day surgical morbidity and mortality in patients with Crohn's disease undergoing ileocolectomy: National Surgical Quality Improvement Program database analysis.

Daniel F, El Kouzi Z, Mrad J et al. · 2025 · Updates in surgery

Preoperative use of biologics has been inconsistently reported to be associated with increased frequency of infectious and surgical anastomotic complications in inflammatory bowel disease patients. We aimed to evaluate the rates of 30-day…

View details →DOI: 10.1007/s13304-025-02238-6
Negative / Null Result ReportMedicine

Short Breaks During the Workday and Employee-Related Outcomes. A Diary Study.

Albulescu P, Macsinga I, Sulea C et al. · 2025 · Psychological reports

In contemporary, high-speed work settings, ensuring the well-being of employees is of paramount importance. The current study builds on this concern about employee well-being and aims to explore the complex connection between workload (as…

View details →DOI: 10.1177/00332941251317632