A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20233 results in Negative / Null Result Report · page 292 of 675
Takano Y, Shirai T, Tanaka Y et al. · 2026 · Scientific reports
This study aimed to elucidate the differences between subjective and objective symptoms of edema during the menstrual cycle in female university students with regular menstruation. The study included 29 female university students with…
Mutavdzic P, Kokovic T, Gakovic B et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Carotid artery stenosis has traditionally guided therapeutic decision-making; however, plaque morphology and composition are increasingly recognized as more reliable indicators of cerebrovascular risk than…
Jackson PD, Helwig M, Bbuye M et al. · 2026 · PLOS global public health
Post-tuberculosis lung disease (PTLD) is a frequent complication after TB cure, affecting millions globally. Yet, its mechanisms, particularly the role of lipid mediators (LMs) in resolution of inflammation are not clear. This study aimed…
Herrera-Torres OA, Flores-Zapata J, Ferreyro-Bravo F · 2026 · Nutricion hospitalaria
Introduction Introduction: the estimation of body fat mass (FM) can be performed using different methods. Although Dual-Energy X-ray Absorptiometry (DXA) is considered the reference technique due to its precision and reproducibility, its…
Fu J, Han P, Xu J et al. · 2026 · PeerJ
Objective This study aimed to analyze the correlations between pathological characteristics, risk factors, and inflammatory biomarkers in patients with thymic epithelial tumors (TETs) undergoing surgical resection. Methods A retrospective…
Albayrak HC, Taşın S, İsmatullaev A · 2026 · Polymers
This in vitro study evaluated the effects of whey protein isolate and concentrate on surface roughness, color stainability, and translucency of 3D-printed definitive resins. Five 3D-printed resins were tested: Alias Dental Crown (AC),…
De Silva S, Charles-Nelson A, McQuilten Z et al. · 2026 · Australian critical care : official journal of the Confederation of Australian Critical Care Nurses
Background Survivors of critical illness often have poor health-related quality of life (HRQoL). However, it is unclear what factors are associated with changes in HRQoL after critical illness. Objectives The aim of this study was to…
Almutairi M, Mousa I, Alqahtani R et al. · 2026 · Scientific reports
Single-shade composite restorations can adapt to the tooth structure, improve esthetics, and reduce reliance on shade selection. The objective of this study was to assess the effect of four different children's beverages on the color…
DuPaul GJ, Kern L, Dever BV et al. · 2026 · Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
Objective Behavioral parent training is a first-line psychosocial intervention for young children with Attention-Deficit/Hyperactivity Disorder. Traditional face-to-face delivery is limited by access to therapists, feasibility, and/or…
Wen B, Wu X, Ma X et al. · 2026 · Frontiers in immunology
The therapeutic strategy for Idiopathic Pulmonary Fibrosis (IPF) has undergone a fundamental transformation over recent decades. Combination therapy with glucocorticoids and immunosuppressants, particularly the "triple therapy" regimen…
Sukmarova ZN, Simonenko VB · 2025 · Kardiologiia
Despite significant advances in pharmacological, interventional, and surgical treatments for cardiovascular diseases (CVDs) in recent decades, it appeared that the effectiveness of standard treatments has reached a ceiling, and growing…
Zhou J, Jiang X, Liu Q et al. · 2026 · Cancer metastasis reviews
Efforts to translate advances in immunology into anti-cancer immunotherapies have progressed rapidly in recent years. Six antibodies acting on programmed death ligand 1 or programmed death 1 pathways were approved in 75 cancer indications…
Rourke LM, Byrt CS, Long BM et al. · 2025 · Preprint
Cyanobacteria rely on bicarbonate (HCO 3 - ) as the primary inorganic carbon (Ci) source for photosynthesis in aquatic environments. To use of this Ci source, cyanobacteria employ CO 2 concentrating mechanisms (CCMs) that elevate…
Kakaletsis N, Ntaios G · 2025 · Polish archives of internal medicine
Embolic stroke of undetermined source (ESUS) represents up to one‑sixth of ischemic strokes, and is associated with an annual recurrence risk of 4%-5% despite contemporary secondary prevention. The hypothesis that oral anticoagulation…
Gweon TG, Kim SJ, Myung DS et al. · 2026 · Gastrointestinal endoscopy
Background and aims Insufficient submucosal lifting because of pretreatment with forceps biopsy frequently complicates endoscopic treatment of rectal neuroendocrine tumors (NETs) and potentially affects procedural outcomes. Despite…
Xu H · 2026 · Nutrition & metabolism
BACKGROUND: Epidemiological data consistently associate low vitamin D status with elevated cardiovascular risk, yet causal mechanisms remain contested. METHODS: This review synthesized evidence through a protocol-guided approach, with…
Horsburgh CR Jr, Jenkins HE, Kendall EA et al. · 2026 · IJTLD open
Background Active screening for TB may help address the global TB burden, but the optimal screening strategies are not defined. We have reviewed the effectiveness of community-wide active screening programmes to assess the characteristics…
Stasinos I, Voulgaris T, Kouimtsidis IA et al. · 2026 · World journal of gastrointestinal pharmacology and therapeutics
Background Risk of post colonoscopy colorectal cancer is related to adenoma miss rate (AMR) during colonoscopy. Artificial intelligence (AI) and Endocuff Vision are tools both used to increase adenoma detection rate (ADR). Aim To assess…
Lengyel B, Armos R, Bojtor B et al. · 2025 · Pharmaceuticals (Basel, Switzerland)
Vitamin D is well established for its skeletal effects, being a cornerstone of several endocrine disorders. In recent years, it has come under investigation as a potential disease-modifying drug in several endocrine disorders through its…
Sadoul M, Balança B, Dailler F et al. · 2025 · Neurosurgical review
Aneurysmal subarachnoid hemorrhage (aSAH) is associated with significant morbidity, particularly related to delayed cerebral ischemia (DCI). Hyponatremia, defined as a serum sodium level < 135 mmol/l, is a common complication of aSAH and…
Klinghammer K, Graeven U, Ivanyi P et al. · 2026 · Oncology research and treatment
Introduction Elderly, frail, or cisplatin-ineligible patients with recurrent or metastatic squamous cell carcinoma of the head and neck (R/M HNSCC) have a poor prognosis. To date, no standard of care has been defined for this population.…
Ge Y, Wang X, Zhang Y et al. · 2026 · Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
Objectives This study aims to assess the efficacy of total hysterectomy versus radical hysterectomy in the treatment of gastric-type endocervical adenocarcinoma (GEA). Methods Patients diagnosed with GEA from 2001 to 2021 were derived from…
Bakakos A, Sotiropoulou Z, Anagnostopoulos N et al. · 2025 · Respiratory medicine
Chronic obstructive pulmonary disease (COPD) remains a leading cause of morbidity and mortality around the globe. Its main characteristics are persistent respiratory symptoms and progressive airflow limitation, both of which are driven by…
Bellamy D, Vickery K · 2026 · Infection, disease & health
Background In accordance with AS5369:2023, disinfection processes need to undergo routine performance qualification (PQ) as part of in-field validation. Automated high-level disinfection (HLD) devices therefore need to undergo PQ.…
Yang Q, Li J, Ding L et al. · 2026 · Cancer management and research
Background Growing research findings highlight the potential of inflammatory markers measured after surgery as prognostic indicators for survival outcomes in rectal carcinoma patients. However, their precise clinical significance remains…
Wong A, Cheah K, Papathanakos G et al. · 2026 · Anaesthesiology intensive therapy
Introduction Fluid management in critically ill patients relies on clinical assessment, fluid balance calculations and, increasingly, point-of-care ultrasound. However, the rela-tionships between these assessment modalities remain poorly…
Xu T, Grubbs JB, Kraus SW · 2025 · Addictive behaviors
As sports betting legalization expands across the United States, understanding its effects on problem gambling remains crucial for evidence-based policy development. This longitudinal study tracked 112 American sports bettors over two…
Ke TM, Lin T, Chow WH et al. · 2026 · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Introduction Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is the standard treatment for esophageal cancer, but the role of adjuvant chemotherapy remains unclear. This study investigates the survival benefits of adjuvant…
Schneble CA, Miltenberg B, Jurgensmeier K et al. · 2025 · The American journal of sports medicine
Background Arthrofibrosis is seen in 1.7% to 38% of patients after anterior cruciate ligament reconstruction (ACLR) and has been associated with worse postoperative patient-reported outcomes. There are limited data regarding the optimal…
Rowland S, Brummel K, Aatre R et al. · 2026 · Case reports in medicine
Familial dysbetalipoproteinemia (FDB) is a lipid disorder characterized by defective clearance of triglyceride-rich lipoprotein remnants. Definitive diagnosis has relied on genetic markers, lipid profiles, and specialized lipid assays…