A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19843 results in Negative / Null Result Report · page 289 of 662
Mirpour K, Alijanpourotaghsara A, Pouratian N · 2025 · Preprint
Abstract Parkinson’s disease (PD) involves progressive neurodegeneration and distinctive structural and functional alterations in cortico-basal ganglia circuits. This study proposes bridging the gap between structural and functional…
Ntoumenopoulos G, Hansell L, Neindre AL et al. · 2026 · Australian critical care : official journal of the Confederation of Australian Critical Care Nurses
Background The extent of pulmonary aeration present on admission to the intensive care unit (ICU) as determined by the lung ultrasound score (LUSS) may be useful to predict weaning from mechanical ventilation. The aim of this study was to…
Harris KM, Curby TW, Goldston DB et al. · 2026 · Psychological services
Rates of adolescent psychiatric hospitalization have increased significantly over the last decade. Despite heightened risk for life-threatening behavior and readmission in the year following hospitalization, mental health service use has…
Acevedo L, Fernández-Sarmiento J, Mulett H et al. · 2026 · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Objectives To compare survival, clinical characteristics, complications, and duration of extracorporeal membrane oxygenation (ECMO) support in pediatric patients with severe adenoviral respiratory infections vs. those with other viral…
Dvořáková M, Chládková K · 2025 · Journal of speech, language, and hearing research : JSLHR
Purpose The mismatch negativity (MMN), a neural index of speech sound discrimination, is reportedly stronger for phonemically relevant speech sound differences than for phonemically irrelevant differences, even if the former are…
Zenkov VS, Cockburn IA, Lin R et al. · 2025 · Preprint
A relatively small number of liver-localized CD8 T cells can provide sterilizing protection against exposure to Plasmodium sporozoites. Previously published mathematical model-based simulations of randomly searching for an infection T…
Hutchison SM, DiazPinzon N, Oberlander TF et al. · 2025 · Autism research : official journal of the International Society for Autism Research
Over the past 10 years, research has suggested no negative effect on second language exposure in children with autism spectrum disorder (ASD), yet, parents and professionals may be concerned that using a second language with a child with…
· 2006
Immune globulin G (IgG) is a normal component of breastmilk. Data from 2 mothers indicate that IgG concentrations in milk are normal or higher and IgM levels in milk are normal or lower during intravenous immunoglobulin (IVIG) therapy. The…
Kerns EV, Engel S, Codner PA et al. · 2025 · Preprint
Schistocephalus solidus is a parasitic cestode with a complex, multi-host life cycle. S. solidus reproduces in its terminal host either by exchanging gametes with similarly sized individuals or selfing. Fertilized eggs then pass through…
Pontes MR, Abadie M, Ribeiro LP et al. · 2025 · Perspectives in Ecology and Conservation
Global warming is driving shifts in rainfall and temperature patterns, and projections indicate an increase in frequency and intensity of climate anomalies. These changes influence wildlife disease dynamics, affecting pathogen development,…
Cassart T, Kyranides MN, Vandevelde S et al. · 2025 · Personality disorders
This study examined the existence and validity of variants of callous-unemotional (CU) traits. Data were available for 309 detained boys ( M age = 16.96) who completed self-reports, experimental tasks, and were administered a diagnostic…
Sitton MJ, McDonald R, Rosenfield D et al. · 2026 · Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43)
Emotional support from a caregiver is theorized to benefit adolescents after sexual abuse, yet the empirical evidence for this is inconsistent. The present study examines the cross-sectional relation between caregiver emotional support and…
de Berker HT, Rivers CM · 2026 · The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
ObjectiveTo establish whether mobile applications (apps) are used as part of routine care for patients with cleft lip and palate in the UK and Republic of Ireland and to determine what role apps could play in the delivery of care.DesignA…
Ito N, Fukumoto S · 2025 · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
A 10-year-old girl developed bilateral gonalgia and waddling gait. Biochemical and imaging studies showed hypophosphatemia with impaired proximal tubular phosphate reabsorption and high intact fibroblast growth factor 23 (FGF23) level,…
Tourigny-Ruel G, Bailey B, Jean-Charles S et al. · 2026 · Headache
Objective This study aimed to evaluate whether a single dose of intravenous dexamethasone, when added to standard abortive therapy, reduces relapse of migraine after emergency department (ED) discharge in children and adolescents.…
Piot L, Nazzi T, Boll-Avetisyan N et al. · 2025 · Infant behavior & development
Consonants have been proposed to be more important than vowels in lexical processes (i.e., C-bias). This study investigated the existence and strength of the C-bias using a familiar word recognition conflict task, in which recognition…
Han X, Chen M, Jiang Y et al. · 2026 · BMC research notes
OBJECTIVE: We used three sound pressure levels (30 dB, 40 dB, and 50 dB) to perform the acoustic-cued water maze test to determine a suitable sound pressure level for the test. RESULTS: The sound pressure levels at 40 dB and 50 dB were…
Rosenheim JA, Cluff E, Morrow K · 2025 · Journal of economic entomology
The European earwig F. auricularia L. is an omnivore that has only recently been identified as a direct, fruit-feeding pest of citrus. Here, we start to build the basic tools needed for integrated pest management for this species. We…
Verrender A, Manley J, Wallace NK et al. · 2025 · Bioelectromagnetics
In order to understand Idiopathic Environmental Intolerance attributed to Electromagnetic Fields (IEI-EMF), it has been argued that it is crucial to test for effects of radiofrequency electromagnetic fields (RF-EMF) on biomarkers, given…
Morgan MM, Hickey CM · 2026 · European journal of pain (London, England)
Background Many people use cannabis to self-medicate for pain. Little is known about the impact of pain on tolerance and spontaneous withdrawal to delta-9-tetrahydrocannabinal (THC), the primary psychoactive compound in cannabis. Our…
Parham M, Aghaali M, Adeli SH et al. · 2025 · International journal of endocrinology and metabolism
Background Diabetes is a major global health issue, affecting over 8.5% of adults worldwide and significantly increasing the risk of cardiovascular diseases (CVDs). However, the association between diabetes-related macrovascular…
Erb WM, Porter LM, Voyt R et al. · 2025 · American journal of primatology
Among primates, maternal infant care may vary in response to several factors including litter size, reproductive history, and health status. In cooperative breeders, maternal investment may also depend on the amount of help their group…
Corregidor-Castro A, Romano A, Butler M et al. · 2024 · Preprint
Recent climate warming has led to a reduction in bird body size and a relative elongation of their appendages, consistent with Bergmann’s and Allen’s ecogeographical rules. These changes are generally interpreted as thermoregulatory…
Casado-Ruiz J, Castaño-Leon AM, García-Escudero L et al. · 2025 · Journal of neurosurgery
Objective Blunt cerebrovascular injuries (BCVIs) are associated with significant morbidity and mortality. To identify patients with BCVI who were undetected using the classic criteria, researchers designed the expanded Denver screening…
Gladstone JJ, Lehman M, Decker M · 2025 · Journal of experimental psychology. Applied
We investigated the influence of childhood poverty on financial decision making under threat by replicating the findings of Griskevicius et al. (2011b), which found that individuals from lower socioeconomic backgrounds tend to make riskier…
Servais A, Schomaker J, Bastin C · 2024 · Preprint
Whether exposure to a novel environment in virtual reality improves subsequent verbal memory or not is still debated. The present study aims to replicate previous positive findings. To do so, we assessed whether exploration of a novel…
Zehavi-Dorin T, Kutzscher AE, Badr M et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)
Purpose To compare global peripapillary and perifoveal vessel densities between primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG) patients with the same glaucoma severity using optical coherence tomography angiography…
Guo J, Pratt J, Walther DB · 2025 · Attention, perception & psychophysics
The nature of visual processes underlying scene perception remains a hotly debated topic. According to one view, scene and object perception rely on similar neural mechanisms, and their processing pathways are tightly interlinked.…
Sarsangi P, Mohammadi M, Nadjarzadeh A et al. · 2025 · The British journal of nutrition
There is a lack of information from Middle Eastern countries regarding diet-disease associations. We examined dietary glycaemic and insulinemic potential in relation to risk of incident diabetes among a large group of Iranian adults. The…
James KK, Storm BC · 2025 · Behavioral sciences (Basel, Switzerland)
Pretesting and posttesting have long been implemented in classrooms as methods of testing and improving learning. Prior research has been mixed on the relative benefits of pretesting versus posttesting, with some studies finding pretesting…