A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19843 results in Negative / Null Result Report · page 278 of 662
Mark S, Schwartenbeck P, Hahamy A et al. · 2026 · eLife
Humans' ability for generalization is outstanding. It is flexible enough to identify cases where knowledge from prior tasks is relevant, even when many features of the current task are different, such as the sensory stimuli or the size of…
Floridi G, Gargiulo M, Aburto JM · 2026 · Population research and policy review
Since 2006, Mexico has experienced a surge in homicides due to national policies and international influences on drug trafficking activities. Although the effects of the so-called "Drug War" have been extensively studied in demography and…
Grossman A · 2026 · Frontiers in neuroscience
Background Autism spectrum disorder (ASD) prevalence has increased markedly across high-income countries, including Norway, yet environmental drivers remain poorly understood. We hypothesized that historical lead exposure may inversely…
Sesay FA, Oware K, Violette LR et al. · 2026 · The Journal of infectious diseases
Doxycycline treats and prevents several bacterial and parasitic infections and has been proposed as a possible treatment for Trichomonas vaginalis. Nested in a trial of doxycycline postexposure prophylaxis among cisgender women in Kenya,…
Hassan M, Al Balah O, Hegazy A et al. · 2026 · Journal of the Saudi Heart Association
Background Transcranial photobiomodulation (TPBM) using near-infrared (NIR) light is a novel, non-invasive neuromodulation strategy with potential to enhance neurorecovery. While preclinical studies are promising, clinical evidence in…
MacMillan MB, Neath I, Roodenrys S · 2024 · Memory & cognition
A word's orthographic neighborhood is the set of words that differ from the target word by one letter. Both Roodenrys (2009) and Robert et al. (Journal of Psycholinguistic Research, 44, 119-125, 2015) posit that orthographic neighbors are…
Woodbury J, Offerdahl E · 2024 · CBE life sciences education
Team-based learning (TBL) is a highly intense active learning pedagogy that uses a cycle of preclass preparation, formative assessment for readiness, mini-lectures, and complex team exercises. Consistent with the literature on active…
Bickerstaff L, Trinkl J, Munkwitz S et al. · 2025 · F1000Research
Background The photic sneeze reflex (PSR) is a common but underexplored phenomenon where bright light triggers sneezing, affecting ~30% of the population. This study aimed to characterise the light conditions inducing PSR. Methods One male…
Bahadoran S, Vaeznia S, Hassanpour H · 2026 · Veterinary and animal science
This study evaluated the effects of dietary Echinacea purpurea supplementation on immune regulation, oxidative stress, and cellular aging in broiler chickens reared at high altitude (2100 m). One hundred and eight day-old male Ross 308…
Klaiman T, Ianotte L, Josephs M et al. · 2023 · Preprint
Abstract Background : Heart failure (HF) is one of the most common reasons for hospital admission and is a major cause of morbidity, mortality, and increasing health care costs. The EMPOWER study was a randomized trial that used remote…
Leger K, Dong J, DeBruine LM et al. · 2023 · Scientific reports
Perceptions of the trustworthiness of faces predict important social outcomes, including economic exchange and criminal sentencing decisions. However, the specific facial characteristics that drive trustworthiness perceptions remain poorly…
Yoon S, Rottenberg J · 2025 · BMC psychology
Background Does what a person desires to feel (affect valuation) predict their future affective reaction to salient life events? We tested this idea in the context of an exam, a key achievement-oriented event for college students. Methods…
Singstock M, Abdul Khader AHS, Wayant C et al. · 2026 · The oncologist
Background Oncology clinical trials, regardless of success in meeting their primary endpoint, often suffer from spin-the misrepresentation of research findings. Despite dramatic improvements in myeloma outcomes, numerous recent myeloma…
Cusimano C, Kim J, Wong J · 2025 · Proceedings of the National Academy of Sciences of the United States of America
It is common to say that people feel entitled to rewards-they think they have earned or deserve them-based on their effort and achievement. However, effort and achievement draw on different principles to justify reward. They can also…
Nakata Y, Watanabe Y, Ozaki A · 2026 · Cureus
Background The purpose of this study was to evaluate whether the workstyle reform, aimed at improving physician health and safety, achieved a secondary goal of enhancing surgical productivity by applying the Malmquist Index (MI) model. We…
Rajaraman R, Kassaye I, Sharma SS et al. · 2026 · Antimicrobial agents and chemotherapy
The aim of this study was to determine the antiamoebic efficacy of povidone-iodine when used as an adjunct to topical biguanide therapy for Acanthamoeba keratitis. Patients with smear- or culture-positive Acanthamoeba keratitis received…
Makin AD, Rahman A, Bertamini M · 2020 · Preprint
Previous work has shown that symmetrical or regular stimuli are judged as lasting longer than asymmetrical or irregular ones, even when actual duration is matched. This effect has been replicated with different methods and stimuli types,…
Pinto R, Ferreira R, Alves P et al. · 2025 · Healthcare (Basel, Switzerland)
Background : Healthcare-associated infection drives morbidity and unplanned hospital use in haemodialysis. We aimed to determine whether an adapted British Renal Society Infection Risk Screening Tool, applied during a nurse-led vascular…
Andrade G, Gamboa L, Campo-Redondo M · 2026 · Frontiers in psychology
Background Beliefs about free will are central to philosophical and scientific conceptions of agency, and experimental work suggests that weakening such beliefs can reduce honesty, self-control, and helping. Yet little is known about how…
Chen C, Zhang W, Chu C et al. · 2026 · Gland surgery
Background Thyroid malignancies pose a significant global health burden, especially in women. Sex hormones are crucial for thyroid function, but their relationship with thyroid malignancy remains unclear. This study investigates the causal…
Hamilton F, Mitchell RE, Constantinescu A et al. · 2023 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Severe malaria remains a deadly disease for many young children in low- and middle-income countries. Levels of interleukin (IL)-6 have been shown to identify cases of severe malaria and associate with severity, but it is unknown…
Oda T, Houshmand Chatroudi A, Yotsumoto Y · 2026 · Journal of vision
Flicker-induced time dilation refers to the robust illusion whereby temporally modulated visual stimuli are perceived as lasting longer than static stimuli. Although flicker-induced time dilation has been consistently demonstrated, it…
Xu X, Zang X, Liu H et al. · 2026 · The Journal of international medical research
ObjectiveTo assess the causal effects of specific eating habits on ischemic stroke risk and functional outcomes using Mendelian randomization.MethodsThis two-sample Mendelian randomization study used genetic variants associated with 32…
Lin WT, Yang JL, Lin CY et al. · 2026 · JAC-antimicrobial resistance
Objectives Among patients with daptomycin-resistant and vancomycin-resistant Enterococcus faecium bloodstream infection (BSI), the optimal definitive therapy is uncertain. We estimated the dose effect of daptomycin (≥11 mg/kg versus 8 to…
Ünal K, Taş Torun Y, Erol ME et al. · 2026 · World journal of clinical pediatrics
Background Generalized anxiety disorder (GAD) is a prevalent psychiatric condition in children and adolescents, frequently linked to difficulties in daily functioning and academic performance. Increasing evidence suggests that immune…
Li J, Lee P, Jones BC et al. · 2025 · PloS one
The tendency for men to find younger adult women more attractive has been hypothesised to reflect preferences for cues of reproductive potential. To further test this hypothesis, we investigated the possible relationship between…
Simpson NH, Bishop DV, Newbury DF · 2021 · Preprint
Language disorders in children are highly heritable, but progress in identifying genetic variants that contribute to language phenotypes has been slow. Here we applied a novel approach by identifying SNPs that are associated with gene…
McKean J, Underwood P, Yasinzai AQK et al. · 2026 · Cancers
Background/objectives Pancreatic ductal adenocarcinoma is an aggressive malignancy with poor long-term survival. While surgical resection followed by adjuvant chemotherapy remains the standard of care for resectable disease, a substantial…
Sadil P, Cowell RA, Huber DE · 2024 · Psychonomic bulletin & review
In the "serial dependence" effect, responses to visual stimuli appear biased toward the last trial's stimulus. However, several kinds of serial dependence exist, with some reflecting prior stimuli and others reflecting prior responses.…
Orhan BE, Karadağ B, Alkasasbeh WJ et al. · 2026 · Frontiers in nutrition
Introduction Problematic social media use (PSMU) and caffeine use disorder (CUD), a behavioral pattern without formal diagnostic status and a DSM-5 condition listed for further study, respectively, share phenomenological features…