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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19840 results in Negative / Null Result Report · page 275 of 662

Negative / Null Result Report

Memory for US valence without memory for US identity? Decomposing contingency memory in evaluative conditioning with a multinomial modeling approach

Bading KC, Béna J, Barth M et al. · 2026 · Preprint

Evaluative conditioning (EC) refers to a change in the evaluation of a conditioned stimulus (CS) following its pairing with a positive or negative unconditioned stimulus (US). Theories of EC commonly assume that such effects depend on…

View details →DOI: 10.31234/osf.io/twuh4_v1
Negative / Null Result ReportMedicine

Radiopaque markers in children with functional constipation: Potential role in diagnosis, therapy, and outcomes.

Gomez-Suarez R, Lin E, Gershon E et al. · 2026 · Journal of pediatric gastroenterology and nutrition

Objectives To evaluate the clinical utility of the simplified colon transit protocol of radiopaque markers (SROM) in pediatric functional constipation (FC). Methods Retrospective study of children meeting Rome IV criteria for FC undergoing…

View details →DOI: 10.1002/jpn3.70428
Negative / Null Result ReportMedicine

Resting-state functional connectivity of the default mode network as a predictor for escitalopram response in adolescents with depression.

Jang M, Lee KH, Shin J et al. · 2026 · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Adolescent depression differs from adult depression in neurobiology and treatment response. Although resting-state functional connectivity (rsFC) of the default mode network (DMN) has been linked to treatment response in adults, its value…

View details →DOI: 10.1038/s41386-026-02442-x
Negative / Null Result ReportMedicine

Stop Right Now, Thank You Very Much: Psychopathic Traits, Externalizing Dimensions, and Interpersonal Proximity.

Perkins ER, Flum MW, Plate RC et al. · 2026 · Journal of personality disorders

Psychopathy involves disruptions in affiliation and threat sensitivity, but these are hard to disentangle behaviorally. This preregistered study (independent sample N s = 175 and 173) used clinical-forensic and transdiagnostic measures…

View details →DOI: 10.1521/pedi.2026.40.2.166
Negative / Null Result ReportOpen accessMedicine

Predicting Positive Affect in Infancy.

Grossmann T, Miller H, Allison O · 2026 · Developmental science

Positive affect (PA) is integral to health and development, yet its early origins remain largely unexplored. In this pre-registered study (N = 78), we investigated whether infant-specific biological and social-behavioral factors predict PA…

View details →DOI: 10.1111/desc.70192
Negative / Null Result ReportOpen accessMedicine

Mentalizing and Attachment From Infancy to Young Adulthood: Insights From the Metera Adoption Study.

Zournatzidis P, Vorria P, Krana E et al. · 2026 · Personality and mental health

Mentalizing is a socio-cognitive capacity that develops within early attachment relationships, but institutional care may disrupt this process. Although adoption significantly improves developmental outcomes, it remains unclear whether…

View details →DOI: 10.1002/pmh.70084
Negative / Null Result ReportMedicine

Comparative Validation of Scoring Systems in Acute Traumatic Central Cord Syndrome: Acute Traumatic Central Cord Syndrome Score, Central Cord Score, and Subaxial Cervical AO Spine Injury Score for Surgical Decision Making, Recovery, and Timing of Surgery.

Kumar AA, Lim HL, Saffari SE et al. · 2025 · Journal of neurotrauma

Acute traumatic central cord syndrome (ATCCS) is the most common form of incomplete spinal cord injury. Treatment recommendations for ATCCS patients are largely from North America, and their applicability to Asian populations remains…

View details →DOI: 10.1177/08977151251406611
Negative / Null Result ReportMedicine

Clinical Features, Treatment Outcomes, and Cytokine Levels in Pediatric Tularemia Patients in Türkiye.

Cakici O, Aykac K, Seyrek BE et al. · 2026 · The American journal of tropical medicine and hygiene

Tularemia is a rare zoonotic infection with marked geographic clustering and long interepidemic periods. Pediatric data, particularly those on host immune responses during active disease and treatment, remain scarce. The authors aimed to…

View details →DOI: 10.4269/ajtmh.26-0084
Negative / Null Result ReportMedicine

Longitudinal Bidirectional Associations Between Early Adolescents' Externalizing and Posttraumatic Stress Symptoms and Substance Use Patterns.

Dunn CB, Farrell AD · 2026 · Research on child and adolescent psychopathology

Prior research has identified externalizing and internalizing pathways to adolescent-onset substance use, but few studies have considered how psychopathology is associated with the development of polysubstance use during early adolescence.…

View details →DOI: 10.1007/s10802-026-01451-0
Negative / Null Result ReportMedicine

Parental Psychological Distress and Perceived Child Externalizing Behaviors: Examining Mediators and Bidirectional Effects.

Anderson AJ, Rodriguez CM, Henson JM · 2026 · Child psychiatry and human development

Parental psychological distress is a commonly examined risk factor for the emergence of child problem behaviors, but the factors that contribute to that relationship-such as limited parental resources like greater social support and coping…

View details →DOI: 10.1007/s10578-026-01997-6
Negative / Null Result ReportMedicine

Predicting Social Motivation and Interactions in Schizophrenia: An Ecological Momentary Assessment Study.

Abel DB, Fulford D, Fiszdon JM · 2026 · The Journal of nervous and mental disease

Aim Researchers have studied mechanisms underlying social motivation in schizophrenia, including reward learning, hostile attribution bias, and defeatist performance beliefs. Yet, existing work is limited by the use of laboratory paradigms…

View details →DOI: 10.1097/nmd.0000000000001872
Negative / Null Result ReportMedicine

Time Matters: Possible Predictors of the Number of Appointments During the First Year After Hearing Aid Fitting.

McCabe SC, Ramirez K, Dyer S et al. · 2026 · American journal of audiology

Purpose Follow-up care after hearing aid fitting is recommended, yet clinicians lack data on the expected number of follow-up appointments needed and which patients require more support. This study aimed to characterize follow-up service…

View details →DOI: 10.1044/2026_aja-25-00240
Negative / Null Result ReportMedicine

Prognostic Impact of Quantitative CT Disease Extent and Pattern in Fibrotic Hypersensitivity Pneumonitis.

Fernández Pérez ER, Humphries SM, Lynch DA et al. · 2026 · Annals of the American Thoracic Society

Rationale Quantitative CT using multiple instance learning (MIL)-usual interstitial pneumonia (UIP) classifier and data-driven textural analysis (DTA) provides objective and reproducible measurements of disease pattern and extent,…

View details →DOI: 10.1093/annalsats/aaoag116
Negative / Null Result Report

Understanding Burnout in University Students With Physical Impairments: The Protective Roles of Social Support and Self- Concept

Onyedire NG, Ikenegbu T, Edward PU et al. · 2026 · Preprint

Abstract Background University students with physical impairments often face burnout in mainstream settings due to stigma, social barriers, and inadequate support. While social anxiety may heighten risk, self-concept and social support…

View details →DOI: 10.21203/rs.3.rs-8881107/v1
Negative / Null Result Report

Class Composition Effects in Achievement and Interest and the Role of the Learning Environment Revisited: A Conceptual Replication and Extension of Lavrijsen et al. (2022)

Kopatz M, Wagner W, Neuendorf C et al. · 2026 · Preprint

Class composition is a key contextual factor in students’ academic development. Prior research has mainly focused on class mean achievement, yet less is known about other composition characteristics, possible differences for students with…

View details →DOI: 10.31234/osf.io/zkg9r_v1
Negative / Null Result ReportMedicine

Ethnic-racial socialization and sociopolitical development among emerging adult college students of color.

Berkley S, Hoyt LT, Zeiders KH et al. · 2026 · Journal of research on adolescence : the official journal of the Society for Research on Adolescence

This study used multilevel growth modeling to examine associations between ethnic-racial socialization (ERS) and sociopolitical development among undergraduates of color (N = 125) attending predominantly White institutions during the 2016…

View details →DOI: 10.1111/jora.70156
Negative / Null Result ReportMedicine

Performance validity tests in a large racially and linguistically diverse pediatric and young adult clinical sample: Investigations of the TOMM, MVP, and MSVT.

MacAllister WS, Désiré N, Brooks BL · 2026 · The Clinical neuropsychologist

Objective There is strong support for the use of performance validity tests (PVTs) in all neuropsychological evaluations, however, research examining racial, ethnic, and linguistic differences in failure rates remains scarce, particularly…

View details →DOI: 10.1080/13854046.2026.2648272
Negative / Null Result Report

Temperature-sensitive cytoplasmic incompatibility across divergent Wolbachia partly reflects cifB transcription, not endosymbiont density

Bagchi B, Van Vlaenderen L, Wheeler T et al. · 2026 · Preprint

Maternally transmitted Wolbachia bacteria are common in insects, with many strains altering host reproduction through cytoplasmic incompatibility (CI). CI kills embryos fertilized by Wolbachia -bearing males unless those embryos also carry…

View details →DOI: 10.64898/2026.03.31.715596
Negative / Null Result ReportMedicine

Lymphatic Vessel Density or Area Are Not Reliable Prognostic Factors in Oral Cancer.

Cronblad IA, Warvik CE, Bjerkli IH et al. · 2026 · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology

Background Oral tongue squamous cell carcinomas (OTSCC) frequently metastasise via lymphatic vessels, thus lymphangiogenesis may enhance tumour cell dissemination by increasing tumour-lymphatic interactions. The prognostic significance of…

View details →DOI: 10.1111/jop.70148
Negative / Null Result ReportMedicine

Developmental regulation in adolescents with epilepsy who attend regular school: A comparative study part II.

Pfeiffer JP, Pinquart M, Neubauer BA · 2026 · Epilepsy & behavior : E&B

Objective Using strategies for achieving age-specific goals is essential for developmental regulation. In a previous study, we demonstrated that adolescents with epilepsy have difficulty achieving some of their goals, which necessitates…

View details →DOI: 10.1016/j.yebeh.2026.110971
Negative / Null Result ReportOpen accessMedicine

Insights into the influence of dog and guardian demographics, nutrition, and relationship on raw feeding practices.

Balousis P, Abood SK, Brazeau L et al. · 2026 · Frontiers in veterinary science

Introduction Raw meat-based diets (RMBD) are increasingly popular among dog guardians, yet the role of personal nutrition habits and pet-guardian relationships in their adoption remains unclear. This study examines how these factors,…

View details →DOI: 10.3389/fvets.2026.1793754
Negative / Null Result Report

Effect of Intravenous Lipid Emulsion Therapy on Xenobiotic Plasma Partitioning and Short-Term Neurological Outcome in Companion Animals with Suspected Neurotoxicosis: A Case Series

Voorhorst A, Pouzot-Nevoret C, Vernooij JC et al. · 2026 · Preprint

Intravenous lipid therapy (ILE) is used to treat neurotoxicosis in companion animals, but clinical evidence for in vivo xenobiotic partitioning and benefit remains limited. This study evaluated associations between the log n-octanol/water…

View details →DOI: 10.20944/preprints202602.1330.v1
Negative / Null Result ReportMedicine

The HBA-3 score: a simple bedside tool to predict cage subsidence after TLIF.

Najjar E, Khan S, Quraishi NA et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Background Cage subsidence is a common radiographic finding following transforaminal lumbar interbody fusion (TLIF), but its clinical relevance remains uncertain. Hounsfield Unit (HU) values from preoperative CT scans have emerged as…

View details →DOI: 10.1007/s00586-026-09906-0
Negative / Null Result ReportMedicine

Impact of patient-reported taxane-induced peripheral neuropathy on dose reductions or worsening quality of life in Black women with breast cancer: Analysis from ECOG-ACRIN EAZ171.

Ballinger TJ, Zhao F, Jiang G et al. · 2026 · Cancer

Background Black patients with breast cancer experience higher rates of taxane-induced peripheral neuropathy (TIPN), which may compromise chemotherapy dose delivery and health-related quality of life (HRQOL). Using the prospective…

View details →DOI: 10.1002/cncr.70466
Negative / Null Result ReportMedicine

Impact of adherence to six-month home-based HIIT on cardiorespiratory fitness in older adults.

Fosstveit SH, Feron J, Lohne-Seiler H et al. · 2026 · BMC sports science, medicine & rehabilitation

Background High-intensity interval training (HIIT) was originally designed to improve athletic performance, but a growing body of research over the past decade has highlighted its positive impact on various other health outcomes. However,…

View details →DOI: 10.1186/s13102-026-01750-5
Negative / Null Result ReportMedicine

The Association Between Social Determinants of Health, Race, and Sex on Risk for Readmission After Heart Transplantation.

Lemos C, Vargas F, Donald EM et al. · 2026 · Journal of cardiac failure

Background Women, racial and ethnic minority groups, and patients of low socioeconomic status (SES) face barriers linked to adverse outcomes after heart transplantation (HT). Data are lacking regarding the association of these demographics…

View details →DOI: 10.1016/j.cardfail.2026.04.016