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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19840 results in Negative / Null Result Report · page 272 of 662

Negative / Null Result ReportMedicine

The use of partially slatted floor designs as an alternative to littered systems in broiler chickens. II. The effects on welfare and behavioral traits.

Çavdarcı H, Sarıca M, Erensoy K et al. · 2026 · Tropical animal health and production

This study investigated the effects of different flooring designs on the welfare and behavioral traits in fast-growing broilers. A total of 600 day-old Ross-308 chickens were randomly allocated to five treatment groups: fully littered…

View details →DOI: 10.1007/s11250-026-05149-9
Negative / Null Result ReportMedicine

Sublethal effects and bioaccumulation of "smart" anti-corrosion nanoadditives spiked in sediment in the ragworm Hediste diversicolor.

Bruni M, Perina F, Figueiredo J et al. · 2026 · Aquatic toxicology (Amsterdam, Netherlands)

Metallic corrosion poses an economic problem worldwide and is often mitigated by adding corrosion inhibitors (CIs) to protective coatings. Conventional CIs, such as 2-mercaptobenzothiazole (MBT) and benzotriazole (BTA), exhibit toxicity to…

View details →DOI: 10.1016/j.aquatox.2026.107912
Negative / Null Result ReportMedicine

Changes in Gait Kinematics with Continuous Intrathecal Baclofen Infusion for Spasticity After Acquired Brain Injury: A Comparison of Implanted and Non-Implanted Cohorts.

Chow JW, Yablon SA, Stokic DS · 2026 · NeuroRehabilitation

BackgroundAlthough several studies have examined gait changes associated with continuous intrathecal baclofen (CITB) infusion for spasticity in ambulatory patients with acquired brain injury (ABI), none has included a control…

View details →DOI: 10.1177/10538135261459634
Negative / Null Result ReportOpen accessMedicine

Mid-term outcomes and hemodynamic performance of Edwards 19-mm-labeled aortic valve bioprostheses: a single-center retrospective study.

Gyoten T, Akatsu T, Kuroda T et al. · 2026 · Journal of cardiothoracic surgery

Background This study aimed to evaluate clinical outcomes after surgical aortic valve replacement with third-generation Edwards (Edwards Lifesciences, Irvine, CA, USA) 19-mm-labeled aortic valve bioprostheses, including a rapid-deployment…

View details →DOI: 10.1186/s13019-026-04158-x
Negative / Null Result ReportMedicine

Characteristics of the Tongue Coating Microbiome and Its Subtype Differences in Patients with Inflammatory Bowel Disease.

Shen J, Yu X, Xu J et al. · 2026 · Microorganisms

Inflammatory bowel disease (IBD) is associated with microbial dysbiosis, yet subtype-specific alterations in the tongue-coating microbiome remain insufficiently characterized. In this cross-sectional study, tongue-coating samples from 158…

View details →DOI: 10.3390/microorganisms14061381
Negative / Null Result ReportMedicine

Evaluation of parotid and submandibular salivary glands by ultrasonography in patients using antidepressants: a case control study.

Tanrıverdi S, Yeşiltepe S · 2026 · BMC oral health

Background Antidepressants are widely prescribed group of medications frequently associated with xerostomia. Although alterations in salivary flow among antidepressant users have been extensively investigated, there is a paucity of data…

View details →DOI: 10.1186/s12903-026-08892-5
Negative / Null Result ReportMedicine

Comparison of Post-Landing Stability During Basketball Jump Shots Under Real and Virtual Defensive Pressure.

Sun Y, Lee J, Wen X et al. · 2026 · Research quarterly for exercise and sport

The basketball jump shot is a fundamental skill in competitive play, and defensive pressure has been shown to influence movement execution and post-landing control. This study investigated post-landing stability during basketball jump…

View details →DOI: 10.1080/02701367.2026.2665730
Negative / Null Result ReportMedicine

Radiographic correction of medial-column malalignment after minimally invasive versus open talonavicular arthrodesis: A single-centre comparative cohort study.

Werneburg F, Beschauner J, Felsberg M et al. · 2026 · Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons

Background Talonavicular (TN) arthrodesis can be performed open or minimally invasively (MIS); whether MIS reproduces the radiographic medial-column re-alignment of open surgery remains unclear. Methods Retrospective cohort of 56 feet (32…

View details →DOI: 10.1016/j.fas.2026.06.004
Negative / Null Result ReportMedicine

Respiratory syncytial virus incidence and clinical outcomes in patients with inflammatory bowel disease: a National Veterans Affairs cohort study.

Khan N, Sundararajan R, Caldera F et al. · 2026 · Inflammatory bowel diseases

Background Data describing the incidence and clinical outcomes of respiratory syncytial virus (RSV) infection among patients with inflammatory bowel disease (IBD) are limited. Methods We conducted a nationwide retrospective cohort study…

View details →DOI: 10.1093/ibd/izag103
Negative / Null Result ReportMedicine

Serum Ischemia-modified albumin levels in mild to moderate rosacea: an exploratory case-control study.

Şen O, Çakmak SK, Hayran Y et al. · 2026 · Cutaneous and ocular toxicology

Background Rosacea is a chronic inflammatory dermatosis in which oxidative stress has been implicated as a pathogenic factor. Ischemia-modified albumin (IMA) is a serum biomarker of oxidative stress not previously evaluated in rosacea.…

View details →DOI: 10.1080/15569527.2026.2692382
Negative / Null Result ReportMedicine

Evaluating the Quality of Artificial Intelligence-Generated Rubrics and Grading Reliability in Student-Written Reflection Assignments.

Dicken S, DeLeon N, Gutierrez EJ et al. · 2026 · American journal of pharmaceutical education

Objective To investigate whether generative artificial intelligence (genAI) can improve pharmacy assessment practices, specifically, rubric development, and the grading of student-written reflection assignments. Methods Sample…

View details →DOI: 10.1016/j.ajpe.2026.102014
Negative / Null Result ReportMedicine

Purine Metabolism Alterations in Patients with Chronic Heart Failure: A Cross-Sectional Study of Associations with Iron Status, Oxidative Stress, and Anemia.

Konysbek Y, Turar A, Molotov-Luchanskiy VB et al. · 2026 · Metabolites

Background/Objectives : Anemia and iron dysregulation are common in chronic heart failure (CHF), but additional metabolic mechanisms may contribute to these alterations. This study aimed to evaluate purine metabolism and oxidative stress…

View details →DOI: 10.3390/metabo16060432
Negative / Null Result ReportMedicine

Long-Term Outcomes After Percutaneous Coronary Intervention With the Polymer-Free Biolimus-Coated BioFreedom Stent Versus the Biodegradable-Polymer Sirolimus-Eluting Orsiro Stent in Patients With Acute Coronary Syndromes.

Noori M, Christiansen EH, Hougaard M et al. · 2026 · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

Background The polymer-free biolimus A9-coated BioFreedom stent (BF-BCS) releases a lipophilic drug that may provide a potent anti-inflammatory effect in patients with acute coronary syndromes (ACS). Five-year efficacy and safety of BF-BCS…

View details →DOI: 10.1002/ccd.70549
Negative / Null Result ReportOpen accessMedicine

Endocrine Autoimmunity and Inflammatory Signatures in Pediatric Celiac Disease: Context-Dependent Patterns.

Greco M, Mirabelli M, Misiti R et al. · 2026 · Diagnostics (Basel, Switzerland)

Background: Celiac disease (CD) is frequently associated with autoimmune disorders such as Hashimoto's thyroiditis and type 1 diabetes. Endocrine-specific autoantibodies may emerge during the course of CD, but their true prevalence and…

View details →DOI: 10.3390/diagnostics16091330
Negative / Null Result ReportMedicine

Neural Correlates for Anticipating and Observing Goal-Directed Actions in Autism.

Krol MA, Skodova T, Jellema T · 2026 · Autism research : official journal of the International Society for Autism Research

We investigated possible atypicalities in activation of cortical motor-related circuits in young adults with Autism Spectrum Conditions (ASC) and typical-development (TD) when observing others' actions. Activation of these circuits is…

View details →DOI: 10.1002/aur.70272
Negative / Null Result ReportMedicine

The Effect of Posterior Implant Restoration on the Survival, Coronal, Pulpal, and Periapical Status of Adjacent Teeth.

Park JH, Jeon S, Seo MS · 2026 · Clinical implant dentistry and related research

Objectives This retrospective study evaluated the long-term effect of implant adjacency on the prognosis of adjacent natural teeth. Materials and methods We included 345 patients who underwent posterior implant placement and prosthetic…

View details →DOI: 10.1111/cid.70166
Negative / Null Result ReportMedicine

Indoor discomfort from ground transportation traffic vibration and noise-Comparison between Vietnamese and Japanese young participants.

Tung NT, Matsumoto Y, Yokoshima S et al. · 2026 · The Journal of the Acoustical Society of America

This research investigated discomfort responses to combined whole-body vibration and noise in Vietnamese and Japanese participants. Twenty stimuli, comprising five vibration magnitudes and six noise levels induced by ground transportation…

View details →DOI: 10.1121/10.0043936
Negative / Null Result ReportMedicine

Comparison of obstetric, maternal, and neonatal outcomes between preterm prelabor rupture of membranes at 34 + 0-36 + 6 weeks and term prelabor rupture of membranes at ≥ 37 weeks.

Ay O, Bahçeci P, Taşkıran D et al. · 2026 · BMC pregnancy and childbirth

Background To compare preterm prelabor rupture of membranes (PPROM) at 34 + 0-36 + 6 weeks with term prelabor rupture of membranes at ≥ 37 weeks in terms of obstetric outcomes, maternal morbidity, and short-term neonatal outcomes. Methods…

View details →DOI: 10.1186/s12884-026-09511-5
Negative / Null Result ReportMedicine

Comparative Investigation of Perceptions Between Adolescents with Idiopathic Scoliosis and Their Parents Regarding Body Image and Brace-Related Stress.

Xyda G, Bekas V, Kastrinis A et al. · 2026 · Studies in health technology and informatics

The conservative management of Adolescent Idiopathic Scoliosis (AIS) with rigid bracing imposes a significant psychological burden. This study investigated the convergence or divergence of views between female adolescents with AIS and…

View details →DOI: 10.3233/shti260734
Negative / Null Result ReportMedicine

Ibandronate Use in Osteoporotic Vertebral Fractures: A Retrospective Clinical Study Integrated with Exploratory Network Pharmacology and Cross-Cohort Transcriptomic Analysis.

Albayrak M, Guner E, Ugur F et al. · 2026 · Biomedicines

Background: Ibandronate is a nitrogen-containing bisphosphonate used in osteoporosis; however, its relationship with vertebral-fracture-related outcomes, pain trajectories, and broader inflammatory-skeletal signaling remains incompletely…

View details →DOI: 10.3390/biomedicines14061315
Negative / Null Result ReportMedicine

Frailty in a low-risk elective setting: a quality improvement study at Shouldice Hospital.

Paasch C, Svendrovski A, Usher J et al. · 2026 · Hernia : the journal of hernias and abdominal wall surgery

Purpose This study aims to evaluate the impact of frailty on postoperative outcomes after Shouldice primary inguinal hernia Repair (SPIHR) as a quality control measure in a highly standardized elective setting. Methods This quality…

View details →DOI: 10.1007/s10029-026-03760-1
Negative / Null Result ReportMedicine

Assessment of fetal cardiac function using the modified myocardial performance index in fetuses with growth restriction: a prospective observational study.

Ates C, Karaaslan O · 2026 · BMC pregnancy and childbirth

Background Accurate differentiation between constitutionally small fetuses and those affected by true fetal growth restriction (FGR) remains a major clinical challenge, particularly in fetuses with estimated fetal weight between the 3rd…

View details →DOI: 10.1186/s12884-026-09509-z
Negative / Null Result ReportMedicine

Interprofessional learning in diverse Middle Eastern maternity teams.

Mohan S, Reagu S, Lindow S et al. · 2026 · Journal of interprofessional care

This study aimed to assess a Middle Eastern maternity team's perceptions and attitudes toward interprofessional education (IPE), examine factors that may influence these perceptions, and consider their potential implications. Within…

View details →DOI: 10.1080/13561820.2026.2667302
Negative / Null Result ReportMedicine

Complications following stock, customized, and extended total alloplastic temporomandibular joint replacement: a 10-year retrospective cohort study.

Rustemeyer J, Ponelis E, Sari-Rieger A · 2026 · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery

Total alloplastic temporomandibular joint replacement (TMJ-AR) is an established treatment for end-stage temporomandibular joint disease; however, comparative data on different prosthesis designs remain limited. This retrospective 10-year…

View details →DOI: 10.1016/j.jcms.2026.104638