A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20230 results in Negative / Null Result Report · page 266 of 675
Liang C, He J · 2025 · Journal of Visualized Experiments
Autografts are always used in anterior cruciate ligament (ACL) reconstruction. Traditional sources, such as hamstring tendons, bone-patellar tendon-bone, and quadriceps tendon, are popular choices but may result in muscle imbalances and…
Marean-Reardon CL, Reardon PN, Mortimer NT · 2025 · Preprint
Many insect species use self-medication, the consumption of an environmental compound with antipathogen activity, as a defense against pathogen infection. One well-studied example is the interaction between Drosophila melanogaster and…
Bailhache M, El-Khoury F, Chazelas E et al. · 2026 · Academic pediatrics
Objective To determine the association between parental psychological intimate partner violence (IPV) before and around the time of the child's birth, and their use of an emergency department (ED) and hospitalization from 2 months to 10…
Conceicao D, Helayel P, Garcia J et al. · 2025 · Preprint
Abstract Background: Midshaft clavicular fractures account for approximately 5% of bone fractures. Surgical correction is often necessary to ensure adequate functional recovery. There is no consensus in the literature on which Regional…
Türkiş NA, Taşdemir N · 2026 · Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses
Purpose Postoperative nausea and vomiting (PONV) is one of the most common complications in surgical patients during the first 24 hours after general anesthesia. This research aimed to evaluate the effect of cold application on early PONV…
Kazensky L, Lovrić Štefiček MJ, Kašuba V et al. · 2026 · Environmental research
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous air pollutants, where their genotoxic potential raises significant public health concerns. This study evaluated the cytotoxic and genotoxic effects of an environmentally relevant…
McCullen MN, Zerger HM · 2025 · Journal of applied behavior analysis
Previous research supports behavioral interventions, such as contingency management, to increase physical activity. A common limitation of these interventions is a lack of maintenance effects or assessment of the target behavior following…
Zhao Z, Fang Y, Xu G et al. · 2026 · Drug discoveries & therapeutics
This pilot study investigated the protective effect of transfecting brain-derived neurotrophic factor (BDNF) and B-cell lymphoma 2 (bcl-2) genes in retinal ganglion cells (RGCs) using in vivo electroporation in an adult rat optic nerve…
Jabba SV, Erythropel HC, Anastas PT et al. · 2025 · Preprint
Background Since late 2022, the sale of most flavoured tobacco products has been prohibited in California, including menthol cigarettes. Tobacco companies responded by introducing “non-menthol” cigarettes in which menthol was replaced with…
Beeck WV, Lemos M, Niesen AM et al. · 2025 · Preprint
Cephalosporins and other broad-spectrum antibiotics are frequently administered prophylactically into the udder when dairy cows end their lactation cycle, termed dry-off, to reduce mastitis risk. However, the use of antibiotics on cows…
Testa EJ, Fallon RT, Badida R et al. · 2026 · The American journal of sports medicine
Background Posterior glenoid reconstruction for shoulder instability is commonly performed with distal tibia allograft (DTA), but with variable results. Recent evidence shows that distal radius allograft (DRA) has a radius of curvature…
Raposo SR, Lopes RP, Barbosa LF et al. · 2026 · Archives of medical research
Objective To address the major public health problems of increased body weight and obesity, causing conditions such as hypertension and diabetes. Early obesity in childhood and adolescence has more severe long-term health consequences. The…
Israeli R, Steinmetz C, Gannot G et al. · 2026 · Cureus
Introduction Transverse carpal ligament (TCL) release is the standard treatment for carpal tunnel syndrome; however, its potential to alter carpal biomechanics is unclear. Specifically, it has been hypothesized that TCL transection may…
Janssen JC, Schurink AW, Verhoef C et al. · 2026 · European journal of cancer (Oxford, England : 1990)
Background Adjuvant systemic therapy for resected stage III melanoma was introduced in clinical practice following the improved recurrence free survival in randomized controlled trials. However, after ten years of follow-up, adjuvant…
Liang C, He J · 2025 · Journal of visualized experiments : JoVE
Autografts are always used in anterior cruciate ligament (ACL) reconstruction. Traditional sources, such as hamstring tendons, bone-patellar tendon-bone, and quadriceps tendon, are popular choices but may result in muscle imbalances and…
Grewal RS, Berger GK, Pennock AT et al. · 2026 · Journal of pediatric orthopedics
Background Patellofemoral instability is common in adolescent patients and is frequently associated with increased tibial tuberosity-trochlear groove (TT-TG) distances. Medial patellofemoral ligament (MPFL) reconstruction is a standard…
Morey J, Yu J, Brockley L · 2026 · Australian veterinary journal
Introduction Stromal sarcomas are rare canine primary splenic tumors. Previous studies assessing outcomes in dogs with these tumors are limited by small sample sizes, with few dogs receiving adjuvant therapy, leaving the role of…
Santaularia N, Arnau A, Torà N et al. · 2026 · Journal of cardiopulmonary rehabilitation and prevention
Purpose Our purpose was to assess the efficacy of a phase III cardiac rehabilitation (CR) program, based on counseling in the maintenance of physical exercise, on the time spent on physical exercise per week in patients with ischemic heart…
Shin C, Kim JM · 2026 · Journal of movement disorders
Nocturnal hypokinesia (NH) is common in patients with moderate-stage Parkinson's disease (PD). This open-label, single-arm pilot study aimed to assess the effect of bedtime opicapone administration on NH and to evaluate the clinical…
Cordeiro CFdS, Andrade MGdO, Galdi LV et al. · 2025 · Field Crops Research.
Peanut (Arachis hypogea L.) cultivars (cv) have different root morphology, which, combined with soil water availability, can change the response to phosphorus (P). This study evaluated peanut yield, P uptake, and P agronomic efficiency –…
Dupont W, Poulin-Charronnat B, Madden-Lombardi C et al. · 2025 · Journal of cognitive neuroscience
Although both motor imagery (MI) and low-frequency sound listening have independently been shown to modulate brain activity, the potential synergistic effects that may arise from their combined application remains unexplored. Any further…
Dauder-Bosch E, Martin-Martinez JM · 2025 · Preprint
Room temperature self-healing polyurethanes (PUs) generally showed limited mechanical properties. In order to improve the mechanical properties of PUs without sacrificing their self-healing ability, in this study, different amounts of…
Faiss R, Krumm B, Cubel C et al. · 2025 · The Journal of physiology
This study investigated endocrine and steroidal blood markers in 31 male elite cyclists monitored over 7 weeks, including a 3 week altitude training camp either at 2050 m (n = 19) or 3000 m (n = 12). Serum samples were analysed for…
Fay ML, Khouja BA, Newkirk R et al. · 2025 · Journal of food protection
Powdered infant formula (PIF) has previously been shown to support the survival of bacterial foodborne pathogens including Cronobacter sakazakii, Listeria monocytogenes, and Salmonella enterica at various storage temperatures. However, the…
Somogyi F, Pézsa NP, Jerzsele Á et al. · 2026 · Antioxidants (Basel, Switzerland)
As the human population continues to grow, the demand for pork increases, and the management of infectious diseases in swine from a One Health standpoint is becoming more important than ever. To prevent antimicrobial use as much as…
Pai P, D’Mello RS, Nayak S et al. · 2025 · Preprint
Abstract Histone deacetylases (HDACs) are enzymes responsible for removing acetyl groups from histone proteins, resulting in chromatin condensation and repression of genes. They regulate expression of genes, cell cycle, and multiple…
Cau R, Natale L, Cademartiri F et al. · 2026 · European journal of radiology
Objective This study aims to investigate the demographic, laboratory, clinical, and cardiovascular magnetic resonance (CMR) correlates of post-myocardial infarction pericarditis (PMIP), as well as its impact on outcomes in patients with…
Farrell M, Singh A, Mayhew PD et al. · 2026 · Journal of the American Veterinary Medical Association
Objective To compare CT-derived anatomical geometry of the soft palate and clinical outcome following folded-flap palatoplasty (FFP) or traditional staphylectomy (TS). Methods Client-owned French Bulldogs were prospectively enrolled…
Liepe K, Hoang TM, Baehr M · 2026 · European journal of nuclear medicine and molecular imaging
Purpose The diagnostic performance of [ 99m Tc]Tc-PSMA SPECT/CT is contingent upon the individual attributes of the patients' prostate cancer. The aim of the study was to analyse these relationships in order to suggest thresholds that may…
Watanabe Y, Kohinata K, Tome W et al. · 2026 · Oral radiology
Objectives The purpose of this study was to evaluate the impact of X-ray beam angulation and image receptor positioning on the quantification of alveolar bone mineral density (BMD) using intraoral radiographic technique. Methods Intraoral…