A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20230 results in Negative / Null Result Report · page 265 of 675
Liu W, Liu J, Su Y et al. · 2026 · BMC women's health
Purpose Fear of cancer recurrence (FCR) is a prevalent psychological concern among breast cancer survivors, and identifying influencing factors is crucial for designing effective interventions. We aimed to investigate the relationship of…
Yoon Y, Yoon JS, Ko J · 2026 · Korean journal of ophthalmology : KJO
Purpose To compare the surgical outcomes of dacryoendoscopy-aided silicone tube intubation (STI) and endoscopic dacryocystorhinostomy (endo-DCR) for complete nasolacrimal duct obstruction (NLDO), and to identify factors associated with…
Lin Y, Wei X, Su H et al. · 2026 · BMC ophthalmology
Purpose Small-incision lenticule extraction (SMILE) is a widely used procedure for correcting myopia and myopic astigmatism. However, variability in refractive outcomes, particularly astigmatic correction, remains a concern. This study…
Zhang L, Sheng Z · 2026 · Cancer informatics
Objectives To investigate the prognostic value of ferroptosis-related and immune-related transcriptional features in bladder urothelial carcinoma (BUC) and to evaluate whether their integration provides incremental prognostic information…
Chai Y, Shi T, Jiang H et al. · 2026 · Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology
Background Fibular allograft (FA) augmentation is proposed to address the lack of medial column support in plate-fixed proximal humeral fractures; however, the role of FA augmentation in these fractures remains inadequately elucidated. Our…
Kürkçü MF, Şeker GE, Şeker D et al. · 2026 · Viral immunology
The potential role of bovine leukemia virus (BLV), a zoonotic deltaretrovirus, in human breast carcinogenesis remains controversial, and evidence from seroepidemiological studies is limited. This study aimed to evaluate BLV IgG…
García-Gómez B, Jarillo-Ochoa M, García-Rojo E et al. · 2026 · Andrology
Introduction Penile elongation patterns lack objective scientific validation, and their association with vascular mechanisms of erectile dysfunction (ED) remains unclear. The objective is to define objective grower and shower profiles…
Kang D, Eun SD, Park J · 2026 · Scientific reports
Stroke survivors living in the community often experience persistent impairments in muscle strength, balance, mobility, and cardiorespiratory fitness after hospital discharge, which increase vulnerability during daily activities. This…
Johansson M, Lindberg M, Lundh Å · 2026 · The Journal of dairy research
This study investigated the hypothesis that milk quality traits and milk proteolytic activity vary with lactation number in dairy cows. Milk was collected from 109 individual cows, 20 Swedish Holstein and 89 Swedish Red, from 12 commercial…
Lambright KR, Bunn JA, Newmire DE · 2026 · Journal of strength and conditioning research
Abstract Lambright, KR, Bunn, JA, and Newmire, DE. No effect of menstrual cycle phase on Wingate power outputs or perceived exertion in eumenorrheic women. J Strength Cond Res XX(X): 000-000, 2026-This study examined whether anaerobic…
Andriyanto DB, Syafhan NF, Nurhayati F · 2026 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
BackgroundThe adoption of rituximab biosimilars offers a cost-effective alternative for treating Non-Hodgkin Lymphoma (NHL). However, real-world safety data regarding severe hematological toxicities in the Indonesian clinical setting…
Richard V, De Ridder D, Héritier H et al. · 2026 · Preprint
ABSTRACT Background Childhood overweight and obesity represent major public health challenges, shaped by socio-economic and environmental factors. This study investigates the mediating and moderating role of urban environmental exposures…
Dőri F, Németh F, Arweiler N et al. · 2026 · BMC oral health
Background Periodontal regenerative surgery is a well-established treatment modality for intrabony periodontal defects. Enamel matrix derivative (EMD) is one of the most extensively documented biologic agents, whereas platelet-rich fibrin…
Tojo Y · 2026 · Frontiers in human neuroscience
Listening to music while studying is common, yet it remains unclear whether self-selected popular music facilitates or interferes with memory performance. This exploratory pilot fMRI study examined whether preferred Japanese pop music…
Lee CO, Park SY, Yun Y et al. · 2026 · Acta neurochirurgica
Objective Glioblastoma (GBM) incidence increases with age, and its etiologies may differ between young and elderly patients. This study aimed to investigate genetic differences between young and elderly GBM patients using next-generation…
Rapčan R, Kočan L, Witkovsky V et al. · 2026 · Preprint
Abstract Objective Endoscopic facet denervation (ED) and percutaneous cryoneurolysis (Cryo) have emerged as alternative interventional treatments for lumbar facet joint–mediated pain; however, comparative long-term outcome data remain…
Virta L, Engström-Öst J · 2026 · Ecology and evolution
The effects of elevated temperature are pronounced in high latitudes where warming is faster than the global average. It is unclear how warming and other simultaneous stressors will affect the functioning of trophic levels. To study the…
Vandenbossche V, Valcke M, Maldoy M et al. · 2026 · Anatomical sciences education
Digital media have reshaped anatomy education through the integration of virtual three-dimensional models. Techniques such as surface scanning, enable the development of highly photorealistic anatomical models; however, evidence regarding…
Yahata A, Nakamoto N, Oiwa H · 2026 · Rheumatology international
To investigate the clinical characteristics of muscle-dominant ANCA-associated vasculitis (muscle-dominant AAV) in a consecutive single-center cohort. We retrospectively analyzed consecutive patients newly diagnosed with microscopic…
León-Lloreda A, Muñoz-Sánchez B, Polonio-González M et al. · 2026 · Preprint
INTRODUCTION: Delayed initiation of mepolizumab may influence long-term disease control and the achievement of clinical and functional outcomes in patients with uncontrolled severe asthma (SUA), but no definitive conclusions have yet been…
Jaramillo Quiceno GA, Sarmiento Riveros PA, Arias Perez RD et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine
Introduction/objectives Residual rotational laxity remains a relevant clinical concern after anterior cruciate ligament (ACL) reconstruction. Combined ACL and anterolateral ligament (ALL) reconstruction has been proposed to improve control…
Eren Hİ, Takım U · 2026 · Clinical psychology & psychotherapy
Adjustment disorder (AD) is characterized by disproportionate emotional and behavioural responses to stressors, often leading to significant functional impairment; however, the psychological mechanisms underlying this impairment remain…
Akter T, Aziz MA, Shahid AB et al. · 2026 · BMC research notes
Objectives Breast cancer is a complex malignancy influenced by both genetic and environmental mechanisms. The WDFY4 gene, predominantly expressed in immune tissues, plays a role in immune regulation. However, its application in relation to…
Uesato Y, Inamine S · 2026 · Journal of laparoendoscopic & advanced surgical techniques. Part A
Background The umbilical port is routinely used for camera insertion and specimen retrieval in laparoscopic cholecystectomy (LC). However, the umbilicus is anatomically vulnerable and may be associated with an increased risk of surgical…
Di Lorenzo G, Melluso M, Rodolico A et al. · 2026 · The journal of allergy and clinical immunology. In practice
Background Allergen immunotherapy (AIT) is the only disease-modifying treatment for grass pollen-induced allergic rhinoconjunctivitis (ARC). Three delivery routes-subcutaneous (SCIT), sublingual drops (SLIT-D), and sublingual tablets…
Baulier C, Zappella N, Grall N et al. · 2026 · Anaesthesia, critical care & pain medicine
Background Recent studies have increasingly questioned the efficacy and safety of piperacillin-tazobactam (TZP) in septic patients, particularly those with healthcare-associated intra-abdominal infections (hcIAI). This study assessed…
Ariza-Torrado IP, Groman-Lupa S, Martínez-Córdoba CJ et al. · 2026 · Journal of vitreoretinal diseases
Purpose: To evaluate functional and structural outcomes after application of a single intravitreal dose of faricimab in patients with chronic retinal diseases. Methods: In this observational, longitudinal, prospective study, best-corrected…
Kavgacı A, Kaya Ö, Örün UA et al. · 2026 · Journal of clinical medicine
Background : Congenital heart disease (CHD) represents a major cause of perinatal morbidity and mortality, and fetal echocardiography is essential for its early diagnosis and management. Maternal smoking has been suggested as a potential…
Nassif ND, Roberts EK, Vu SN et al. · 2026 · Future microbiology
Background Lung nodule evaluation is a vital practice in pulmonary medicine. While biopsy remains the diagnostic gold standard, it carries procedural risks. In regions endemic for fungal disease, low-cost, noninvasive testing may help…
Kampel L, Oestreicher-Kedem Y, Horowitz G et al. · 2026 · International journal of oral and maxillofacial surgery
Immunotherapy has brought new hope to patients with locally advanced, recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). This study aimed to evaluate the outcomes at our institution, focusing on the response to…