Negative / Null Result ReportMedicine
Blackman J, Friesen D, Sikkel MB et al. · 2026 · Applied clinical informatics
Objectives The objective of this study is to evaluate whether ChatGPT models can reliably apply the DISCERN instrument, a 16-question human-scored rubric developed in 1999 to evaluate consumer health information, and assess the impact of…
View details →DOI: 10.1055/a-2853-8892 Negative / Null Result ReportMedicine
Stewart KM, Sawicki GS, Young AJ et al. · 2026 · Journal of biomechanics
Individuals post-stroke with hemiparetic gait often experience impaired mobility, which can be restored using powered exoskeletons. Specifically, hip exoskeletons can deliver positive work to the leg to help initiate leg swing; however, it…
View details →DOI: 10.1016/j.jbiomech.2026.113259 Negative / Null Result ReportMedicine
Norling M, Eriksson N, Westerberg E et al. · 2026 · Muscle & nerve
Introduction/aims Physical activity and sleep influence fatigue in myasthenia gravis (MG), and digital health technologies (DHT) enable objective monitoring of these behaviors in daily life. Using this approach, we evaluated whether a…
View details →DOI: 10.1002/mus.70234 Negative / Null Result Report
Amir H, Martini A, Médevielle V et al. · 2026 · Preprint
The rehabilitation of mine-impacted areas through ecological restoration can ensure long-term ecosystem resilience by reestablishing at least part of the original biodiversity. In New Caledonia, large surfaces of mined land need to be…
View details →DOI: 10.22541/au.176826796.62402425/v1 Negative / Null Result ReportMedicine
Orlowska M, Saleh MHA, Decker A et al. · 2026 · Journal of periodontology
Background This randomized controlled trial aims to evaluate alveolar ridge preservation (ARP) with or without a biologically active amnion-chorion membrane (BACM). Methods Thirty patients requiring tooth extraction in the esthetic zone…
View details →DOI: 10.1002/jper.70094 Negative / Null Result ReportMedicine
Nehme Z, Mahony E, Nehme E et al. · 2026 · Resuscitation
Aim To determine whether defibrillation with manual pressure augmentation (MPA) reduces transthoracic impedance and improves cardioversion and survival from initially shockable out-of-hospital cardiac arrest (OHCA) compared with standard…
View details →DOI: 10.1016/j.resuscitation.2026.111121 Negative / Null Result ReportMedicine
Betat A, Santos VD, Oliveira CGA et al. · 2026 · Journal of hypertension
Background Arterial hypertension has been linked to cognitive decline, potentially through cerebrovascular alterations and associations with Alzheimer's disease. A positive correlation between elevated serum cholesterol levels and…
View details →DOI: 10.1097/hjh.0000000000004277 Negative / Null Result ReportMedicine
Kiraly P, Lippera M, Ally N et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose To assess whether external drainage of subretinal fluid (SRF) improves anatomical or visual outcomes in scleral buckle surgery for rhegmatogenous retinal detachment (RRD). Methods Retrospective review of 609 primary scleral buckles…
View details →DOI: 10.1097/iae.0000000000004856 Negative / Null Result ReportMedicine
Azulay N, Singstad BJ, Schirmer H et al. · 2026 · Scientific reports
In Norway, NORRISK2 is the government-recommended risk model for predicting an individual's 10-year probability of getting cardiovascular disease (CVD). This study aims to investigate the potential for improvement of CVD prediction by…
View details →DOI: 10.1038/s41598-026-57003-5 Negative / Null Result Report
Furukawa M, Narita M, Sakamoto I et al. · 2026 · Preprint
Abstract Background Six months of adjuvant S-1 is the standard treatment for resected pancreatic cancer in Japan. Metformin has demonstrated potential anticancer effects in preclinical and observational studies. This study aimed to…
View details →DOI: 10.21203/rs.3.rs-9445035/v1 Negative / Null Result ReportMedicine
Bröer S, Filor V, Bäumer W · 2026 · Journal of veterinary pharmacology and therapeutics
According to the European Association of Establishments for Veterinary Education (EAEVE), a graduate of veterinary medicine should be able to prescribe and dispense "medicines correctly and responsibly in accordance with legislation and…
View details →DOI: 10.1111/jvp.70062 Negative / Null Result ReportMedicine
Jegarl AM, Martin M, Cormier NR et al. · 2026 · Anesthesiology
Background Whether adding a bilateral superficial cervical plexus block to a thyroidectomy enhanced recovery pathway improves postoperative quality of recovery remains uncertain. Methods In a single-center prospective, randomized,…
View details →DOI: 10.1097/aln.0000000000006200 Negative / Null Result ReportMedicine
Jecan A, Melinte RM, Tomoaia G et al. · 2026 · Journal of clinical medicine
Background : Vitamin K2 (menaquinone) has been studied as a molecule with important effects on bone metabolism and has been proposed as a potential adjuvant in fracture healing, particularly under osteoporotic conditions. However, its…
View details →DOI: 10.3390/jcm15124510 Negative / Null Result ReportMedicine
Kılıç HS · 2026 · European journal of dentistry
Objective This article aims to compare the polymerization effectiveness of two curing modes of a polywave LED unit in four conventional resin composites at a 2-mm increment thickness, using bottom/top microhardness ratios as the evaluation…
View details →DOI: 10.1055/s-0046-1820081 Negative / Null Result ReportMedicine
Chang JJ, Foreman B, Kepplinger D et al. · 2026 · Neurosurgical review
Pressure reactivity index (PRx) is a surrogate for cerebral autoregulation and has been used for prognostication in aneurysmal subarachnoid hemorrhage (SAH). We examined patient-specific temporal courses of PRx and identified time…
View details →DOI: 10.1007/s10143-026-04323-9 Negative / Null Result ReportMedicine
Chun SH, Seo S, Cho JH et al. · 2026 · Head & neck
Background The benefit of consolidation programmed cell death protein 1 (PD-1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II-IVB NPC were…
View details →DOI: 10.1002/hed.70329 Negative / Null Result Report
Liang H, Zhang D, An X et al. · 2026 · Preprint
Abstract The rise of generative AI (GenAI) has sparked interest in whether human-AI collaboration can enhance creativity, yet empirical findings remain mixed. This study systematically compared 4 collaboration models (i.e., AI-first,…
View details →DOI: 10.21203/rs.3.rs-8774138/v1 Negative / Null Result ReportMedicine
Gupta N, Seo J, Phan F et al. · 2026 · Heart rhythm
Background Lead dwell time (DT) is associated with increased complexity of cardiac implantable electronic device (CIED) extraction. Optimal strategies for risk mitigation are not well studied. Objective This study aimed to evaluate the…
View details →DOI: 10.1016/j.hrthm.2026.04.025 Negative / Null Result ReportMedicine
Chen YF, Kou HW, Chen TH et al. · 2026 · Journal of gastrointestinal cancer
Purpose Radical surgery is the primary treatment for localized gastric cancer (GC), but the benefit of adjuvant chemotherapy in stage IB GC remains unclear. This study evaluates its impact on recurrence and survival post-gastrectomy.…
View details →DOI: 10.1007/s12029-026-01472-4 Negative / Null Result ReportOpen access
Ole B. Suhr, Stellan Mörner, Anders Holmgren et al. · 2011
Septal systolic strain measurements showed reduced longitudinal function but its localized nature failed to demonstrate radial disturbances in patients with pathologically thickened septum. No difference was found in systolic strain…
View details →DOI: 10.1111/j.1540-8175.2010.01344.x Negative / Null Result ReportOpen accessGeriatrics
Hong-Jhe Chen, Hsun Ou, Ru-Yih Chen et al. · 2025 · BMC Geriatrics
Abstract Background This study investigated the relationship between sleep disturbance, obstructive sleep apnea (OSA), and osteoporosis in older adults. Methods This cross-sectional study involved 326 older adults (mean age: 83.46 years) in elder care institutions in Taiwan. The presence of osteoporosis was assessed using dual-energy X-ray absorptiometry, while sleep quality and OSA risk were evaluated using the Pittsburgh Sleep Quality Index and STOP-Bang questionnaire, respectively. Heart rate variability (HRV) was measured to assess autonomic function. Logistic regression models, adjusted f
View details →DOI: 10.1186/s12877-025-06527-y Negative / Null Result ReportOpen accessSurgery
Camila Lopes Cardoso, Osny Ferreira Júnior, Paulo S. Perri de Carvalho et al. · 2011 · Acta Cirúrgica Brasileira
PURPOSE: To evaluate two treatment modalities of dry socket in rats and to discuss the first findings of the molecular analysis in this experimental model. METHODS: 84 rats underwent a tooth extraction were divided in 4 groups: I-uninfected socket (control), II-infected socket without any treatment, III-infected socket treated with irrigation of 2% sodium iodide and 3% hydrogen peroxide solution, IV-infected socket submitted to curettage, irrigation with physiological saline solution and fulfilled with metronidazole paste as base. The groups were subdivided in postoperative sacrifice periods:
View details →DOI: 10.1590/s0102-86502011000500007 Negative / Null Result ReportOpen accessOrthopedic surgery
Min Zou, Xin Duan, Mufan Li et al. · 2023 · Journal of Orthopaedic Surgery and Research
Abstract Background Treating lateral compression type 1 (LC1) pelvic ring injuries in older patients is controversial. This study evaluated surgical treatments combined with ERAS for treating LC1 pelvic fractures in the elderly. Methods In this retrospective study, patients who underwent surgery with INFIX (supra-acetabular spinal pedicle screws, and a subcutaneous connecting rod; the experimental group) or superior pubic ramus cannulated screw (the control group) fixation of LC1 pelvic fracture from January 2019 to January 2022 were reviewed. Injury radiography and computed tomography were pe
View details →DOI: 10.1186/s13018-023-04219-0 Negative / Null Result ReportOpen accessOils, fats, and waxes
孙玉萍，刘启东，杨亚，仇长璐，黄国栋，莫泳红，胡金华 SUN Yuping, LIU Qidong, YANG Ya, QIU Changlu, HUANG Guodong, MO Yonghong, HU Jinhua · 2023 · Zhongguo youzhi
为了对中包装的大豆油棕榈油煎炸专用调和油配方的开发和煎炸稳定性相关理化指标的选择提供参考，分别以一级大豆油、分提18 ℃棕榈油（一次精炼）及同批次的二次精炼18 ℃棕榈油为煎炸油，模拟薯条在180 ℃下高温煎炸32 h，对3种油品在煎炸过程中的酸值、过氧化值、p-茴香胺值、脂肪酸组成、极性组分含量、生育酚含量等理化指标进行了检测，并对18 ℃棕榈油中的风险因子，如PAH4、苯并（a）芘、3-氯丙醇酯（3-MCPDE）、反式脂肪酸含量进行了分析。结果表明：3种油品的酸值、过氧化值在煎炸过程中变化不明显，而p-茴香胺值、脂肪酸组成、极性组分含量在煎炸过程中变化比较明显；3种油品的生育酚氧化速度总体偏差不大；分提18 ℃棕榈油、二次精炼18 ℃棕榈油中的苯并（a）芘、反式脂肪酸含量均随煎炸时间延长呈缓慢升高的趋势；二次精炼18 ℃棕榈油的3-MCPDE在未煎炸时远高于分提18 ℃棕榈油的，3-MCPDE在煎炸初期降解剧烈，最终达到平衡；分提18 ℃棕榈油与二次精炼18 ℃棕榈油在煎炸稳定性方面没有明显区别，二次精炼不仅损失了部分有益的微量营养成分（如生育酚），还伴生出新的风险因子，如增加了3-MCPDE、反式脂肪酸。综上，酸值、过氧化值不能作为评价煎炸稳定性的敏感指标，而p-茴香胺值、脂肪酸组成、极性组分含量可作为敏感指标联合应用于评价煎炸油煎炸稳定性，另外，应倡导适度加工，以降低精炼过
View details →DOI: https://doi.org/10.19902/j.cnki.zgyz.1003-7969.210791 Negative / Null Result ReportOpen accessMedicine
Hasan M. Al-Dorzi, Abdulaziz Al-Dawood, Fahad M. Al-Hameed et al. · 2022 · Scientific Reports
Abstract There are contradictory data regarding the effect of intermittent pneumatic compression (IPC) on the incidence of deep-vein thrombosis (DVT) and heart failure (HF) decompensation in critically ill patients. This study evaluated the effect of adjunctive use of IPC on the rate of incident DVT and ventilation-free days among critically ill patients with HF. In this pre-specified secondary analysis of the PREVENT trial (N = 2003), we compared the effect of adjunctive IPC added to pharmacologic thromboprophylaxis (IPC group), with pharmacologic thromboprophylaxis alone (control group) in c
View details →DOI: 10.1038/s41598-022-12336-9 Negative / Null Result ReportOpen accessOrthopedic surgery
Diego Zanolli de Solminihac MD, Emilio Wagner MD, Pablo Wagner MD et al. · 2017 · Foot & Ankle Orthopaedics
Category: Bunion Introduction/Purpose: Hallux Rigidus (HR) is characterized initially by a decrease in Hallux metatarsophalangeal joint (MTPJ) dorsiflexion, decreasing the total range of motion. To be able to study different surgical treatment options, a cadaveric model has to be developed that recreates the limited range of motion. Our objective was to develop an Hallux Rigidus cadaveric model by shortening the plantar fascia (PF). Hallux MTPJ range of motion and joint stiffness were evaluated. Methods: 8 cadaveric foot- ankle – distal tibia specimens were prepared, identifying all extensor a
View details →DOI: 10.1177/2473011417s000426 Negative / Null Result ReportOpen accessMedicine
Jae-Hong Kim, Chang-Su Na, Myoung-Rae Cho et al. · 2022 · PLoS ONE
This study aimed to provide preliminary evidence for the efficacy of invasive laser acupuncture (ILA) for chronic non-specific low back pain (CNLBP). This was a single-center, randomized, patient and assessor-blinded, placebo-controlled, parallel-arm, clinical trial with a 1:1:1 allocation ratio that included a full analysis set. Forty-five participants with CNLBP were randomly assigned to the control group (sham laser), 650 group (650 nm-wavelength ILA), or 830 group (830 nm-wavelength ILA) (n = 15/group). All participants received ILA for 10 min, followed by electroacupuncture for 10 min on
View details →DOI: 10.1371/journal.pone.0269282 Negative / Null Result ReportOpen accessTheory and practice of education
Ali Yakar, Bilal Duman · 2022 · International Journal of Contemporary Educational Research
The purpose of the present study is to determine the effects of two multi-modal representations, the use of text and graph for learning, on problem solving, academic achievement and retention when used in a process-based instruction (PBI). The study was designed as quasi-experimental study complying with pretest-posttest control group design. The study group consists of (N=30+34=64) students from the department of classroom teacher education in the Education Faculty of a university from west of Turkey in 2015-2016 academic year. The data in the study were collected through problem solving inve
View details →DOI: 10.33200/ijcer.566067 Negative / Null Result ReportOpen accessBiochemistry
Alper Kucukbasmaci, Ali Sabir · 2019 · Acta Scientiarum Polonorum: Hortorum Cultus
Testing the globally popular grapevine rootstocks for affinity with new grape cultivars or tolerance potential to stress factors like drought is essential for districts where supplemental irrigation is more frequently needed due to the pressures of a global climate change. In this study, a seasonal evaluation of leaf gas exchange, leaf temperature, leaf greenness (chlorophyll content prediction) and vegetative development of Vitis vinifera L. cv. ‘Prima’ grafted to different rootstock genotypes having great variability in drought tolerance, were investigated. The experiment was conducted in a
View details →DOI: 10.24326/asphc.2019.4.6 Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Tadataka Takagi, Fumikazu Koyama, Hiroyuki Kuge et al. · 2024 · Journal of the Anus, Rectum and Colon
Objectives: This study aimed to investigate the impact of the COVID-19 pandemic on the examination and treatment of colorectal cancer (CRC) and on the behaviors of patients and practitioners. Methods: This is a retrospective analysis of the CRC patients who presented to our department between April 2019 and March 2021 and underwent surgery. Clinical presentation of CRC and time from symptom onset to medical presentation were compared between the control (April 2019 to March 2020, n=124) and COVID-19 pandemic periods (April 2020 to March 2021, n=111). Results: Two hundred and thirty-five patien
View details →DOI: 10.23922/jarc.2023-034 