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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20230 results in Negative / Null Result Report · page 263 of 675

Negative / Null Result ReportMedicine

Acute effect of impact and resistance exercise on Wnt signaling modulators, bone and cartilage metabolism.

Boxer B, Zhang Z, Folland JP et al. · 2026 · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Impact and resistance exercise have potent osteogenic effects and may positively affect cartilage through tissue deformation. These effects may be mediated through inhibitors of Wnt signaling, such as sclerostin and Dickkopf WNT signaling…

View details →DOI: 10.1093/jbmr/zjaf128
Negative / Null Result ReportMedicine

Timing of Midurethral Sling Placement During Minimally Invasive Sacrocolpopexy.

Ashmore S, Russo D, Hornbach A et al. · 2026 · Urogynecology (Philadelphia, Pa.)

Importance Surgeons traditionally place the synthetic midurethral sling (MUS) after completing the apical suspension procedure during surgical procedures for pelvic organ prolapse (POP) and stress urinary incontinence (SUI). We hypothesize…

View details →DOI: 10.1097/spv.0000000000001739
Negative / Null Result ReportMedicine

Testing the effects of schema-congruency and agency on collective memories by roleplaying a fictional collective identity.

Çetin OG, Gülgöz S · 2026 · Memory (Hove, England)

The role of agency in collective memory is largely unexplored, and evidence that schema-congruent collective events are more readily integrated than incongruent ones remains largely correlational. Studying these factors experimentally is…

View details →DOI: 10.1080/09658211.2026.2672000
Negative / Null Result Report

Fungal-bacterial interaction unaffected by heatwave conditions

Moreno-Druet M, Pardaens S, Soudzilovskaia NA et al. · 2026 · Preprint

Climate change is reshaping soil microbial communities, yet the impact of warming in bacterial-fungal interactions (BFIs) remains underexplored. We investigated whether heatwave temperature influence BFIs and the mechanism supporting the…

View details →DOI: 10.64898/2026.04.29.721557
Negative / Null Result ReportMedicine

Changes in characteristics and body mass index-SD after guanfacine extended-release administration for ADHD children.

Kawasaki Y, Suzuki Y, Miyazaki K et al. · 2026 · Fukushima journal of medical science

Aim To clarify the change in characteristics and body mass index standard deviation (BMI-SD) after guanfacine extended-release (GXR) administration for attention-deficit/hyperactivity disorder (ADHD) children, we undertook a clinical…

View details →DOI: 10.5387/fms.26-00007
Negative / Null Result ReportMedicine

Compost and rootstock effects on fibrous root physiology and bacterial community composition in young citrus trees under endemic Huanglongbing.

Pugina G, Tardivo C, Monus B et al. · 2026 · Scientific reports

Citrus production in Florida has declined drastically due to Huanglongbing (HLB), a bacterial disease associated with Candidatus Liberibacter asiaticus. This disease significantly reduces fruit yield and quality and shortens the tree's…

View details →DOI: 10.1038/s41598-026-58183-w
Negative / Null Result ReportMedicine

Pollution versus biopollution? Failure of Xenostrobus securis invasion in a heavily polluted estuary of the Bay of Biscay.

Ortiz-Moriano MP, Rivas-Iglesias L, Gutierrez-Rodriguez A et al. · 2026 · Marine pollution bulletin

Invasive species tolerant to pollution may gain a competitive advantage in contaminated environments. This study aimed to assess the accumulation of microplastics (MPs) and heavy metals (HMs) in native (Mytilus galloprovincialis) and…

View details →DOI: 10.1016/j.marpolbul.2026.120008
Negative / Null Result ReportMedicine

Effects of Probiotic <i>Lacticaseibacillus paracasei</i> NSMJ27 on Laying Performance and Gut Health Indicators in Aged Laying Hens.

Vu VA, Kim YB, Kim SK et al. · 2026 · Animals : an open access journal from MDPI

This experiment was designed to determine the effect of the Lacticaseibacillus paracasei ( paracasei ) strain NSMJ27, isolated from Korean fermented vegetable food (home-made kimchi), on laying performance, egg quality, intestinal…

View details →DOI: 10.3390/ani16050792
Negative / Null Result ReportMedicine

Effect of duration of feeding a sorghum silage-based backgrounding diet in an intense postweaning production system for Nellore bulls on growth performance

Pucetti P, Silva JT, Alves JB et al. · 2026 · Animal Feed Science and Technology.

The objective of this study was to evaluate the effects of different backgrounding durations in an intense postweaning production system for Nellore bulls, as compared with immediate adaptation to a corn-based finishing diet. Forty bulls…

Negative / Null Result ReportMedicine

Influence of accent and learning styles on online animation learning.

Zhang Y, Zhang H, Wang Y et al. · 2026 · Cognitive processing

The influence of the interaction between accent and learning styles on learners' learning is an important issue to be considered in online animation design and application. The objective of this study is to reveal the effects of accent and…

View details →DOI: 10.1007/s10339-026-01356-2
Negative / Null Result ReportMedicine

Inclusion of rapeseed cake or oil in the diet of beef cattle reduces enteric methane emissions without affecting animal performance.

Folliard NT, Waters SM, Roskam E et al. · 2026 · Animal : an international journal of animal bioscience

The global methane (CH 4 ) pledge aims to reduce anthropogenic CH 4 emissions by 30% by 2030. Oilseed rape (Brassica napus L), a break crop with 40 million ha cultivated globally in 2022, produces fatty acid-rich by-products that could…

View details →DOI: 10.1016/j.animal.2026.101780
Negative / Null Result ReportMedicine

Outcomes and Complications After LUMiC<sup>®</sup> Endoprosthetic Reconstruction of Periacetabular Defects-A Retrospective Cohort Analysis.

Niemann AS, Ramon R, Mayor J et al. · 2026 · Life (Basel, Switzerland)

(1) Background: The reconstruction of periacetabular defects after tumor resection remains one of the most challenging procedures in orthopaedic oncology. The modular LUMiC ® system was designed to improve fixation stability and reduce…

View details →DOI: 10.3390/life16060955
Negative / Null Result Report

Depth effects of long-term Piliostigma reticulatum residue management under varying planting densities on SOC stocks and pools using DRIFTS

Koomson E, Nkwain Y, Lutz N et al. · 2026 · Preprint

Abstract Background and aims: The West African Sahel faces severe soil degradation and declining productivity due to climate variability and unsustainable land use. Integrating the native shrub Piliostigma reticulatum into cereal-based…

View details →DOI: 10.21203/rs.3.rs-9721145/v1
Negative / Null Result ReportMedicine

Sex, Race, and Ethnicity in National Institutes of Health Career Development Award Submissions and Success: A 20-Year Retrospective Cohort Study.

Koumpias AM, Kirch M, Steppe E et al. · 2026 · Journal of women's health (2002)

Background Obtaining a National Institutes of Health (NIH) career development (K) award is a pivotal milestone for early-career faculty, contributing not only to individual career progression but also to the diversity of the biomedical…

View details →DOI: 10.1177/15409996261454981
Negative / Null Result ReportMedicine

Comparison of explosive power, balance and muscle morphology in female volleyball players with and without chronic ankle instability.

Comlekci M, Yıldız AE, Demirel A · 2026 · BMC sports science, medicine & rehabilitation

Background Ankle sprains are among the most common injuries in athletes, accounting for approximately 80% of all athletic injuries. Recurrent ankle sprains often progress to chronic ankle instability (CAI), which can impair athletic…

View details →DOI: 10.1186/s13102-026-01783-w
Negative / Null Result Report

Intact learning and memory in mice incapable of de novo myelination

Swire M, Nayar SG, Jiang Y et al. · 2026 · Preprint

Summary Motor skill learning stimulates and requires generation of oligodendrocytes (OLs) from their precursors (OLPs) in the adult mouse brain, but the functional role(s) of the newly formed OLs is not known. We asked whether new compact…

View details →DOI: 10.64898/2026.06.12.730403
Negative / Null Result ReportMedicine

The Impacts of Mitoquinone Supplementation on Oxidative Status and Cryo-Survival of Cryopreserved Male Donkey (<i>Equus asinus</i>) Semen.

Abdelnaby EA, Alhaider AK, Emam IA · 2026 · Veterinary sciences

This current study aimed to determine the impact of Mitoquinone (MitoQ) on the quality of frozen-thawed donkey semen. Ejaculates were collected from six male donkeys ( Equus asinus ), and ejaculates were polled and aliquoted into 12…

View details →DOI: 10.3390/vetsci13060510
Negative / Null Result ReportMedicine

Efficacy and safety of morning or evening antihypertensive drug administration on albuminuria in hypertensive patients: an open-label pilot randomized controlled trial.

Trakarnvanich T, Nochaiwong S, Ruengorn C et al. · 2026 · Scientific reports

To date, little is known regarding the treatment effects of different timed-dosing antihypertensive medications among hypertensive patients with albuminuria. We aimed to investigate whether morning or evening dosing of antihypertensive…

View details →DOI: 10.1038/s41598-026-54798-1
Negative / Null Result Report

The flip side of multisensory integration: Sensory processing sensitivity and metacognitive monitoring in the Sound-induced Flash Illusion

Azizi Z, Chan J, Ward T et al. · 2026 · Preprint

Multisensory integration (MSI)–the brain’s ability to combine information from different senses–is crucial for coherent perception and adaptive behavior. While often viewed as a bottom-up process, emerging research shows internal states…

View details →DOI: 10.31234/osf.io/vwg7r_v3
Negative / Null Result ReportMedicine

Human Steering Control Under Unpredictable Disturbances.

Liu JY, Cooke JRH, Selen LPJ et al. · 2026 · The European journal of neuroscience

There are multiple methods for controlling dynamical systems under external disturbances, with some emphasizing robust performance and others prioritizing efficiency. Here, we characterized the control strategies of human steering behavior…

View details →DOI: 10.1111/ejn.70605
Negative / Null Result ReportOpen accessMedicine

Effects of homeopathic remedy supplementation on performance, blood parameters, and behavior of pigs under vaccination and regrouping stress conditions.

Lee H, Sung JY, Son J et al. · 2026 · Journal of animal science and technology

In the modern swine production systems, pigs are often challenged with regrouping and vaccination, which may negatively affect growth performance and behavior of pigs. The objective was to test the hypothesis that a supplemental…

View details →DOI: 10.5187/jast.2025.e28