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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20227 results in Negative / Null Result Report · page 256 of 675

Negative / Null Result Report

Utilizing raw rapeseed press cake in foods: A case study on sensory quality and profile of selected bitter compounds in snack bars

Thorsen JS, Bononad-Olmo A, Toft AM et al. · 2026 · Preprint

ABSTRACT Today’s canola quality rapeseed press cake (RPC) is a protein-rich co-product with potential as human food, but its application is limited due to antinutritional compounds and bitter taste. It remains, however, unknown how…

View details →DOI: 10.64898/2026.03.20.712648
Negative / Null Result ReportMedicine

Beef quality and expression of genes involved in lipid metabolism in the muscle of Nellore and Nellore × Angus steers fed whole shelled corn diets.

Teixeira PD, Casagrande DR, Rodrigues AC et al. · 2026 · Meat science

Sixteen Nellore and Sixteen Nellore × Angus steers with an initial body weight of 353 kg ±25.3 kg were randomly assigned into 2 feeding groups: whole shelled corn without forage (WSC) or WSC with sugarcane bagasse (WSCB), to evaluate…

View details →DOI: 10.1016/j.meatsci.2026.110078
Negative / Null Result ReportMedicine

Chinese Young Children Engage in Social Role-Based Sharing Behavior.

Wu X, Chai Q, He J · 2026 · Developmental science

Role ethics suggests that moral obligations arise from the duties associated with one's social roles. Yet, the influence of social roles on children's moral behavior remains unclear. This research addressed this gap by testing whether…

View details →DOI: 10.1111/desc.70140
Negative / Null Result ReportMedicine

Intraoperative 3D Fluoroscopy Reduces Revision Rates and Improves Reduction Quality in Acetabular Fracture Fixation.

Le Baron M, David G, Ward BA et al. · 2026 · Journal of orthopaedic trauma

Objectives To evaluate whether the use of intraoperative 3D fluoroscopy during acetabular fracture fixation reduces the rate of unplanned returns to the operating room and improves radiographic quality of reduction without increasing…

View details →DOI: 10.1097/bot.0000000000003100
Negative / Null Result ReportMedicine

Poplar CLE peptides promoting ectomycorrhizal symbiosis identified through genome-wide analysis of responsive small secreted peptides.

Bonnot C, Morin E, Da Silva Machado E et al. · 2026 · Plant physiology

Plant small secreted peptides (SSPs) are involved in numerous developmental processes and adaptive plant responses. These include root development, immunity, and symbiotic relationships in herbaceous plants; three processes crucial for…

View details →DOI: 10.1093/plphys/kiag071
Negative / Null Result ReportMedicine

18-Crown-6 ether increases molecular weight of poly(3-hydroxybutyrate) synthesized in Escherichia coli.

Tanaka S, Kikukawa H, Nakai H et al. · 2026 · Journal of bioscience and bioengineering

Molecular weight of polyhydroxyalkanoate (PHA) is a critical factor governing their physical properties, particularly mechanical strength. It is empirically known that molecular weight of PHA varies depending on factors such as the…

View details →DOI: 10.1016/j.jbiosc.2026.01.008
Negative / Null Result ReportMedicine

Safety and Efficacy of Hypofractionated Preoperative Radiation Therapy in Retroperitoneal Sarcoma: A Comparative Study With Conventional Fractionation.

Baek JY, Yu JI, Lee KW et al. · 2026 · Practical radiation oncology

Purpose The role of preoperative radiation therapy (RT) in retroperitoneal sarcoma (RPS) remains controversial across histologic subtypes. Conventional fractionated RT (ConvRT) is the current standard, but hypofractionated RT (HypoRT) is…

View details →DOI: 10.1016/j.prro.2026.02.008
Negative / Null Result ReportMedicine

A randomized trial of iron- and zinc-biofortified pearl millet-based complementary feeding in children aged 12-18 months living in urban slums.

Mehta S, Huey SL, Ghugre PS et al. · 2026 · Clinical nutrition (Edinburgh, Scotland)

Background and aims Biofortification of staple crops with higher concentrations of micronutrients via traditional breeding methods is a sustainable strategy and can possibly complement fortification and other interventions to target…

View details →DOI: 10.1016/j.clnu.2025.11.002
Negative / Null Result ReportMedicine

Effect of paternal resveratrol intake on mitochondria and telomere length in mouse embryos and offspring.

Teramoto N, Kobayashi N, Mitsui K et al. · 2026 · The Journal of reproduction and development

Advanced paternal age affects embryonic development and offspring phenotypes. We previously demonstrated that resveratrol prevents age-associated declines in the mitochondrial DNA copy number (mt-cn) and telomere length (TL) in embryos.…

View details →DOI: 10.1262/jrd.2026-038
Negative / Null Result ReportMedicine

Effect of white and red grape pomace on dry-cured sausages containing additives.

Carrapiso AI, Sánchez-Ordóñez M, Delgado-Adámez J et al. · 2026 · Food science and technology international = Ciencia y tecnologia de los alimentos internacional

The purpose of this study was to investigate for the first time the effect of the enrichment in white or red grape pomace stabilized by high hydrostatic pressure on the characteristics of dry-cured sausages containing additives (75 mg kg…

View details →DOI: 10.1177/10820132261461428
Negative / Null Result ReportMedicine

The Influence of Depth of Anesthesia on Motor Evoked Potentials Monitoring During Spinal Surgery in Youth: A Single-Center Prospective Study (SCOL Study).

Hudec J, Prokopova T, Hulkova M et al. · 2026 · Anesthesia and analgesia

Background Anesthetic agents or some pathophysiological conditions can affect transcranial motor evoked potentials (TcMEP) monitoring. However, the influence of depth of anesthesia on TcMEP reproducibility in youth remains unclear due to…

View details →DOI: 10.1213/ane.0000000000008158
Negative / Null Result ReportMedicine

Characterizing the V516M penicillin-binding protein 2 (PBP2) mutation causing zidebactam resistance in <i>Pseudomonas aeruginosa</i>.

Sastre-Femenia MÀ, Gomis-Font MA, Fernández-Muñoz A et al. · 2026 · Antimicrobial agents and chemotherapy

The triple action of the diazabicyclooctane (DBO) zidebactam (antibacterial activity [penicillin-binding protein 2 {PBP2} inhibitor], β-lactam enhancement [synergy with PBP3 inhibitors], and β-lactamase inhibition [classes A and C])…

View details →DOI: 10.1128/aac.00346-26
Negative / Null Result ReportMedicine

Brain Activity Changes During Bladder Filling in Women With Overactive Bladder After Percutaneous Tibial Neuromodulation.

Tam J, Wengler K, Yang J et al. · 2026 · Neurourology and urodynamics

Purpose Percutaneous tibial neuromodulation (PTNM) is a standard third line therapy for patients with overactive bladder (OAB). While the therapy has demonstrated efficacy, its exact mechanism of action is unclear. Functional neuroimaging…

View details →DOI: 10.1002/nau.70238
Negative / Null Result ReportMedicine

Redefining the role of carbon nanoparticles in colorectal cancer surgery: From lymph node yield to diagnostic paradox.

Lv Y, Wang F, Shen Y et al. · 2026 · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Background Accurate lymph node (LN) staging is critical in colorectal cancer (CRC). Carbon nanoparticles (CNPs), used as a tumor localization agent, incidentally stain LNs, creating uncertainty about their utility for improving staging and…

View details →DOI: 10.1016/j.ejso.2026.111782
Negative / Null Result ReportMedicine

The Opioid Safety Toolkit: An interactive prescription opioid safety toolkit to increase opioid safety literacy and behaviours among people prescribed opioids for pain-a randomised controlled trial.

Nielsen S, Fox F, Lam T et al. · 2026 · Addiction (Abingdon, England)

Background and aims Prescription opioid-related harm remains a significant public health concern. This study aimed to evaluate the efficacy of the Opioid Safety Toolkit, a co-designed, interactive online resource, in increasing naloxone…

View details →DOI: 10.1111/add.70412
Negative / Null Result ReportMedicine

Epidemiologic and Clinical Trends of Pediatric Human Rhinovirus Infections: A 2-year Comparative Analysis From a Single Center.

Yildirim Arslan S, Turanli E, Dinc F · 2026 · The Pediatric infectious disease journal

Background Human rhinovirus is one of the leading causes of pediatric respiratory infections worldwide. Its circulation patterns have shown notable changes in recent years. This study aimed to compare the epidemiologic, clinical and…

View details →DOI: 10.1097/inf.0000000000005171
Negative / Null Result ReportMedicine

Glucocorticoid dose at discharge and the risk of infectious complications and rehospitalization in renal diseases.

Yahata K, Seta K, Osaki K et al. · 2026 · Clinical and experimental nephrology

Background Glucocorticoids have diverse adverse effects, particularly infections that may be severe or opportunistic. Therefore, glucocorticoids are often initiated during hospitalization; however, the optimal glucocorticoid dose at…

View details →DOI: 10.1007/s10157-026-02868-z
Negative / Null Result ReportMedicine

Disinfection by-products in ballast water treated with oxidants - effects of treatment type, filter pre-treatment, test location, and salinity.

Sverdrup LE, Pollestad BM, Sigvaldsen I et al. · 2026 · Chemosphere

Ballast water is essential for ship stability during cargo operations and voyage, but its discharge can introduce invasive aquatic species to new environments. To mitigate this risk, ballast water is commonly treated with oxidants such as…

View details →DOI: 10.1016/j.chemosphere.2026.144899
Negative / Null Result ReportMedicine

Evaluation of a Clinical Practice Algorithm for Pediatric Complicated Pneumonia: A Retrospective, Observational, Single-Center Study.

Ostertag-Hill CA, Cummings OW, Renaud EJ · 2026 · Rhode Island medical journal (2013)

Objective The diagnostic evaluation, antibiotic treatment, and type and timing of surgical intervention for pediatric patients with complicated pneumonia is not standardized and may lead to increased length of stay, more radiation…

Negative / Null Result ReportMedicine

Comparison of Different Lighting Protocols on Female Cat Reproduction.

Lantermino A, Lapuente C, Blanco PG et al. · 2026 · Reproduction in domestic animals = Zuchthygiene

The aim of this study was to describe and compare the effect of different lighting protocols on sexual cyclicity and serum melatonin in domestic female cats. Additionally, anti-Müllerian hormone (AMH) concentrations and ultrasound or…

View details →DOI: 10.1111/rda.70177
Negative / Null Result ReportMedicine

Comparison of the somatic mutations in breast carcinomas in sporadic and BRCA1 carrier patients through targeted next generation sequencing.

Barron CR, Ramineni M, Finkelman BS et al. · 2026 · Human pathology

Objectives Women who carry a germline mutation in BRCA1 have an increased lifetime risk of developing breast cancer (BC). Prior Next-Generation Sequencing (NGS) studies on BCs from patients with germline BRCA1 mutations (gBRCA1) were…

View details →DOI: 10.1016/j.humpath.2026.106144
Negative / Null Result ReportMedicine

Long-term increase in Mediterranean diet adherence combined with decrease in ultra-processed food consumption is associated with reduction in depressive symptoms: Results from the Moli-sani study.

Bracone F, Di Castelnuovo A, Costanzo S et al. · 2026 · Clinical nutrition (Edinburgh, Scotland)

Background and aims Mediterranean diet (MD) has been associated with a reduced risk of depressive symptoms, while high intake of ultra-processed foods (UPFs) has been linked to poorer mental health. However, the long-term combined effects…

View details →DOI: 10.1016/j.clnu.2026.106627
Negative / Null Result ReportMedicine

Single-Leg Balance: Bias for the Non-Preferred Leg in Complex Tasks, But no Association with Footedness.

Marcori AJ, Gamberini MG, Silva Freitas MFD et al. · 2026 · Journal of motor behavior

In unchallenging single-leg balance (SLB) tasks, the lower limbs demonstrate symmetrical control and stability. Balance asymmetries between the legs are expected to increase with task demands, being evident in complex motor tasks. In this…

View details →DOI: 10.1080/00222895.2026.2637973
Negative / Null Result ReportMedicine

Radiation dose for common pediatric computed tomography examinations and evaluation of clinical image quality in pediatric chest CT scans.

Findikli I, Yalcin A, Kasapgil O et al. · 2026 · Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

The increasing use of computed tomography (CT) in pediatric patients has prompted researchers to investigate the radiation dose associated with pediatric CT scans. Studies optimizing image quality and minimizing radiation dose in pediatric…

View details →DOI: 10.1016/j.apradiso.2026.112569
Negative / Null Result ReportMedicine

Psychological Resilience Moderates Autonomous Motivation After Mild Traumatic Brain Injury: A Randomized Controlled Trial of a Remote Walking Program.

Chang YC, Tsai HF, Shi RS et al. · 2026 · The Journal of head trauma rehabilitation

Objective The aim of this study was to evaluate whether a 12-week remotely delivered walking program based on self-determination theory (SDT) improves autonomous exercise motivation in adults with mild traumatic brain injury (mTBI) versus…

View details →DOI: 10.1097/htr.0000000000001153