e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21283 results · page 256 of 710

Negative / Null Result ReportOpen accessMedicine

Interfascial Plane Blocks for Perioperative Analgesia in Dogs Undergoing Laparoscopic Ovariectomy: A Retrospective Study (2020-2025).

Paolini A, Serpieri M, Bonaffini G et al. · 2026 · Animals : an open access journal from MDPI

This retrospective study compared three ultrasound-guided locoregional techniques-transversus abdominis plane (TAP), quadratus lumborum (QL), and caudal thoracic paravertebral (C-TPV) blocks-in dogs undergoing laparoscopic ovariectomy.…

View details →DOI: 10.3390/ani16111612
Negative / Null Result ReportMedicine

Determinants of Patient-Reported Experience After Interhospital Transfer Within an Integrated Health System.

Howick V JF, Lugo-Fagundo NS, Umadat G et al. · 2026 · Journal for healthcare quality : official publication of the National Association for Healthcare Quality

Objective To evaluate patient-reported experiences after interhospital transfer (IHT) within an integrated health system and identify communication and coordination domains associated with overall satisfaction. Methods This retrospective…

View details →DOI: 10.1097/jhq.0000000000000525
Negative / Null Result ReportMedicine

Microfluidic sperm selection versus density gradient centrifugation in ICSI cycles with abnormal semen parameters: a randomized sibling-oocyte study.

Thanapongpibul C, Niransuk P, Sassanarakkit S et al. · 2026 · Scientific reports

Microfluidic sperm selection (MSS) is a centrifugation-free alternative to density gradient centrifugation (DGC) for sperm preparation in intracytoplasmic sperm injection (ICSI). This prospective, randomized sibling-oocyte study included…

View details →DOI: 10.1038/s41598-026-55209-1
Negative / Null Result ReportMedicine

Association of the mitochondrial regulator PGC-1α with diabetes mellitus and myocardial ischemia-reperfusion injury in coronary artery bypass grafting.

Yildiz A, Yazici S, Yildiz Z · 2026 · BMC cardiovascular disorders

Objectives This study aimed to evaluate whether peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) could serve as a marker of myocardial ischemia by examining its association with cross-clamp time, which reflects…

View details →DOI: 10.1186/s12872-026-06151-7
Negative / Null Result ReportOpen accessMedicine

Low-flow oxygen delivery in patients with disturbed consciousness.

Yamada SM · 2026 · Surgical neurology international

Background When low-flow oxygen (O2) delivery is required, a nasal cannula is commonly used. However, no reports have described arterial blood gas analysis in actual patients receiving O2 simultaneously through a mask and a nasal cannula.…

View details →DOI: 10.25259/sni_1393_2025
Negative / Null Result ReportMedicine

Impact of a minimal handling care protocol on intraventricular hemorrhage in preterm infants: a retrospective cohort study.

Uygun SS, Ozturk M, Soylu H et al. · 2026 · BMC pediatrics

Background Premature birth is associated with a high risk of mortality and neurodevelopmental morbidity, with intraventricular hemorrhage (IVH) remaining a major cause of brain injury in preterm infants. Neuroprotective care bundles…

View details →DOI: 10.1186/s12887-026-07091-z
Negative / Null Result ReportMedicine

Susceptibility of sorghum to infestation by Oryzaephilus surinamensis (Coleoptera: Silvanidae) and Trogoderma variabile (Coleoptera: Dermestidae): influence of variety and temperature.

Gourgouta M, Athanassiou CG, Arthur FH et al. · 2026 · Journal of economic entomology

This study evaluated the effects of sorghum variety and temperature on the population growth, frass production, kernel damage, and weight loss caused by Oryzaephilus surinamensis (L.) and Trogoderma variabile, Ballion, two common…

View details →DOI: 10.1093/jee/toag139
Negative / Null Result Report

Perceptions of end-of-life care quality among bereaved closest contacts of community-dwelling older Australians: a cross-sectional survey of the ASPREE cohort

Keon-Cohen ZM, Tran C, Jones D et al. · 2026 · Preprint

Abstract Background High-quality end-of-life care (EOLC) is a recognised health and human-rights priority, yet Australian evidence largely derives from administrative data and cancer-specific, facility-based samples. Little is known about…

View details →DOI: 10.21203/rs.3.rs-9879018/v1
Negative / Null Result ReportOpen accessMedicine

Influence of sport mouth-formed type mouthguards on saliva secretion and composition during jaw activity: a pilot study.

van Vliet KE, Lobbezoo F, van Splunter AP et al. · 2026 · BMC oral health

BACKGROUND: We hypothesized that wearing a mouthguard may affect salivary flow and composition. Therefore, we investigated the impact of mouthguard use on saliva secretion rate and some salivary constituents under different jaw activities.…

View details →DOI: 10.1186/s12903-026-07849-y
Negative / Null Result Report

Investigating Gendered Implicit Bias Among Healthcare Workers in South Africa: Development and Piloting of an Implicit Association Test in a High Tuberculosis and HIV Setting

Medina-Marino A, Shrader C, Axt J et al. · 2026 · Preprint

Abstract Background In sub-Saharan Africa, men with HIV and/or tuberculosis (TB) report negative experiences within health services and demonstrate poorer engagement and treatment outcomes compared to women. We developed and piloted an…

View details →DOI: 10.21203/rs.3.rs-9422562/v1
Negative / Null Result Report

Immediate Effects of Specific Warm-Up and Static Stretching on Cardiovascular and Oxygen Consumption Parameters during 5 Km Treadmill Running

Limphatcharaporn T, Sinsurin K, Sakulsriprasert P et al. · 2026 · Preprint

Abstract Purpose of the study: to examine the immediate effect of specific warm-up and static stretching on cardiovascular response and oxygen consumption during a 5 km treadmill run using a randomized controlled trial. Method: twenty…

View details →DOI: 10.21203/rs.3.rs-9399762/v1
Negative / Null Result Report

Impact of BRAF V600E Mutation on Surgical Management and Outcomes in Low-Risk Differentiated Thyroid Carcinoma (T1–2N0M0)

Králik R, Takácsová E, Durdík Š et al. · 2026 · Preprint

Abstract Background The clinical relevance of the BRAF V600E mutation in the surgical management of early-stage differentiated thyroid carcinoma (DTC) remains unclear. Although common in papillary thyroid carcinoma, its role in guiding…

View details →DOI: 10.21203/rs.3.rs-9407674/v1
Negative / Null Result ReportMedicine

Sacral positioning and interface pressure in the beach-chair position during shoulder surgery: a retrospective, observational study.

Takatori N, Uchiyama Y, Ito H et al. · 2026 · Journal of tissue viability

Background Intraoperative pressure-related skin injuries remain a concern during surgery under general anaesthesia. Although interface pressures have been evaluated in various surgical positions, sacral pressure in the beach-chair position…

View details →DOI: 10.1016/j.jtv.2026.101027
Negative / Null Result Report

Impact of co-administration of proton pump inhibitors on efficacy and safety of oral semaglutide in patients with type 2 diabetes: a single-center retrospective study

Yokoyama T, Uchino T, Yazawa Y et al. · 2026 · Preprint

Abstract Background Oral semaglutide, a glucagon-like peptide-1 receptor agonist, improves glycemic control and reduces body weight in patients with type 2 diabetes. Although proton pump inhibitors (PPIs) have been reported to slightly…

View details →DOI: 10.21203/rs.3.rs-9444720/v1
Negative / Null Result ReportMedicine

Migraine is Associated With Altered Preoperative Endodontic Pain Perception and Mechanical Sensory Function but Not Short-Term Postoperative Pain: A Prospective Clinical Study.

Harun AS, Shikder AHMZH, Moni SD et al. · 2026 · Journal of oral rehabilitation

Background Migraine has been associated with altered nociceptive processing and may influence the clinical presentation of odontogenic pain. This study evaluated whether migraine is associated with preoperative endodontic pain,…

View details →DOI: 10.1111/joor.70249
Negative / Null Result ReportMedicine

Source- and land-use-dependent controls on black carbon accumulation in urban soils: A comparison between an industrial city and a megacity in central China.

Zhan C, Liu S, Kang W et al. · 2026 · Environmental pollution (Barking, Essex : 1987)

Black carbon (BC) is an important component of soil organic carbon (SOC), with implications for carbon sequestration and environmental quality, yet its variability across contrasting urban systems remains insufficiently understood. This…

View details →DOI: 10.1016/j.envpol.2026.128533
Negative / Null Result ReportMedicine

Robotic versus laparoscopic rectal resection: impact on primary postoperative ileus and the role of intraoperative fluid balance: a propensity score-matched cohort study.

Urashima T, Yabuno T, Imanishi K et al. · 2026 · Surgical endoscopy

Background Few studies have directly compared the incidence of primary postoperative ileus (primary POI) between robotic surgery (RS) and laparoscopic surgery (LS) for rectal resection. Methods This retrospective cohort study included…

View details →DOI: 10.1007/s00464-026-12994-0
Negative / Null Result Report

Monarch performance and cardenolide sequestration decline on naturally derived hybrid milkweeds (Asclepias syriaca x speciosa)

Olson-Manning CF, Acharya S, Matuck L et al. · 2026 · Preprint

Abstract Plant hybridization often alters herbivore-relevant traits, yet the effects of hybrid feeding on specialist herbivores, especially those that co-opt host-plant defenses, are largely unknown. We examined how naturally derived…

View details →DOI: 10.21203/rs.3.rs-9919052/v1
Negative / Null Result ReportMedicine

Radial Versus Femoral Access for Diagnostic Coronary Angiography: Insights From a Tertiary Academic Center in Johannesburg.

Ntaka KL, Mpanya D, Adamu UG et al. · 2026 · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

Background The radial artery is the preferred access for performing diagnostic coronary angiograms (DCA). However, data on the safety and efficacy of radial compared to femoral access in low- and middle-income countries is limited. Aims…

View details →DOI: 10.1002/ccd.70654
Negative / Null Result ReportMedicine

Staphylococcus aureus bacteremia: clinical outcomes and predictors of 28-day mortality in a tertiary-care cohort.

Gucluer Kocaoglu MN, Kahraman H, Nayman S et al. · 2026 · BMC infectious diseases

Background Staphylococcus aureus bacteremia (SAB) is associated with substantial short-term mortality, but the relative contributions of methicillin resistance, treatment adequacy, and host-related factors to outcome remain unclear. This…

View details →DOI: 10.1186/s12879-026-13847-w
Negative / Null Result ReportMedicine

The Surgical Outcomes of Brachiocephalic Vein Transection Versus Reconstruction for Locally Advanced Thymic Epithelial Tumors.

Sun J, Xiong Y, Qiu J et al. · 2026 · Annals of surgical oncology

Background Locally advanced thymic epithelial tumors (TETs) may extend into the adjacent brachiocephalic vein (BCV), creating major technical challenges for resection. While BCV reconstruction is traditionally considered after tumor…

View details →DOI: 10.1245/s10434-026-19935-0