A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21707 results · page 256 of 724
Razmeh, Karimi, Dashti et al. · 2026 · Journal of neurology
Hypoxic ischemic encephalopathy (HIE) is a severe brain injury that can lead to death and long-term disability. HIE can be treated with therapeutic hypothermia, and various adjuvant treatments (such as melatonin) are also utilized.…
van Amstel, Simons, Kooreman et al. · 2026 · Breast (Edinburgh, Scotland)
In clinically node-positive (cN+) patients, radioactive iodine ( 125 I) seeds can be considered to mark metastatic axillary lymph nodes before neoadjuvant therapy (MARI-procedure) but potential therapeutic effects remain unclear. This…
Shen, Yan, Yan et al. · 2026 · Journal of environmental sciences (China)
Diazotrophs play a crucial role within the rhizosphere by fixing atmospheric nitrogen and promoting plant growth. However, the diversity of diazotrophic communities and the influences of human activity are largely unclear. This study…
Uludag, Uludag · 2026 · Current medicinal chemistry
Recently, there has been growing interest in the roles of vitamin D and certain platelet characteristics, such as mean platelet volume (MPV). However, the influence of vitamin D levels on these platelet traits is still under discussion.…
Estaji, Ahmadizadeh · 2026 · Journal of psychiatric research
Based on neurocognitive models, the development and maintenance of post-traumatic stress disorder (PTSD) are correlated with cognitive biases, including attention and memory biases, which are associated with imbalanced activation of…
Cazalis-Henry, Seuront, Spilmont · 2026 · Biology letters
Brown macroalgae like Fucus serratus are key ecosystem engineers in intertidal environments and are increasingly threatened by anthropogenic pollution and global change. This study examined how the combined effects of conventional and…
Grub, Naab · 2026 · Digital health
To examine user perceptions of human advisors versus chatbots in mental health apps and assess the impact of algorithm literacy interventions. In an online experiment, participants engaged in simulated chats about digital stress. A…
Maureen, Budiardjo, Wahono · 2026 · Journal of the Indian Society of Pedodontics and Preventive Dentistry
Down syndrome is a genetic condition caused by trisomy 21, often accompanied by orofacial hypotonia and anomalies in stomatognathic development. A hypotonic tongue may alter oral cavity morphology, particularly palatal depth, anterior…
Goh, Sud, Chau et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Renin-angiotensin system inhibitors (RASIs) are recommended to preserve residual kidney function (RKF) in patients on peritoneal dialysis (PD); however, evidence of benefit is inconsistent. This study evaluated…
Ptáček, Musil, Guarnieri et al. · 2026 · International journal of molecular sciences
Amyotrophic lateral sclerosis (ALS) is a common neurodegenerative disorder; to date, there is no long-term effective treatment. Recently, a relationship has been discovered between the human intestinal microbiome and the pathogenesis of…
Deng, Xiang, Li et al. · 2026 · Animals : an open access journal from MDPI
Due to the lack of corn and soybean meal in animal feeding, rice bran meal (RBM) has been proposed as a beneficial substitute for these feedstocks' ingredients. Its fermentation by using diverse microbes has been adopted as a beneficial…
Hazell, Khazova, O'Mahoney · 2026 · Antioxidants (Basel, Switzerland)
Conflicting evidence exists on whether blue or red light modulates nitric oxide (NO) release within skin cells. Using environmentally relevant doses, irradiances and spectral distribution akin to low-level sunlight, we provide evidence…
Tas, Erturk · 2026 · Indian journal of surgical oncology
Due to controversial results, the clinical impact of sex in pancreatic cancer has not been fully clarified. We aimed to investigate the clinical significance of sex in patients with pancreatic cancer in this study. A total of 334…
Elgayar · 2026 · Scientific reports
This trial aimed to explore the effect of supervised breathing exercises (BEs) on depression, sexual function, and exercise capacity in postmenopausal women. Sixty-four depressed postmenopausal women with associated sexual dysfunction were…
Chen, Liu, Xue et al. · 2026 · Molecular pain
The insular cortex (IC), a critical hub for nociception, emotion, and cognition processing, has emerged as a key role in the descending modulation of spinal cord excitability. Although previous studies have suggested that IC may influence…
Balducci, Haxhi, Vitale et al. · 2026 · Acta diabetologica
To assess the effect of a 1-year supervised exercise training program on long-term mortality in people with type 2 diabetes. This is a post hoc analysis of the Italian Diabetes and Exercise Study randomized clinical trial, which enrolled…
Zhang, Song, Ji et al. · 2026 · Ecotoxicology and environmental safety
The rise in electronic waste from the electronics industry has increased environmental and health risks. Pollutants like tris(2-chloroethyl) phosphate (TCEP) and lead (Pb) are particularly concerning for their harmful effects on…
Rezaeinejad, Sepidarkish, Moini et al. · 2026 · Pregnancy hypertension
While cigarette smoking has been paradoxically associated with a reduced risk of preeclampsia, the effect of waterpipe (WP) smoking, an increasingly prevalent form of tobacco use remains poorly understood. This study aimed to investigate…
Ehne, Kastensson, Wedin et al. · 2026 · Journal of bone oncology
The use of postoperative radiotherapy (PORT) as an adjunct to orthopaedic surgery of the long bones is widely recommended. Evidence of the benefits is however sparse. The primary research question of this study was whether PORT reduces the…
Karunayawong, Sukmanee, Butchon et al. · 2026 · BMJ open
Since 1985, the international healthcare community has recommended the ideal rate of caesarean section (CS) to be 10%-15% at the national level. The literature has reported that overused CS without necessary medical indications can be…
Li, Hou, Li et al. · 2026 · Chemistry & biodiversity
Two new pyrrole alkaloids, asiaticain A (1) and asiaticain B (2), two aromatic compounds 3-4, and one steroid 5 were isolated from Lanmaoa asiatica. The structural elucidation of the isolated compounds was determined by using NMR, MS, IR,…
Rodrigues, Macedo, de Paulo et al. · 2026 · Oral surgery, oral medicine, oral pathology and oral radiology
To evaluate the effects of sticky bone a biomaterial composed of Solid-PRF (S-PRF), a variant of platelet-rich fibrin (PRF), and deproteinized bovine bone-on bone formation after tooth extraction performed prior to radiotherapy, with…
Olivieri, Amatori, Battocchio et al. · 2026 · Nanomaterials (Basel, Switzerland)
Gold nanorods (AuNRs) were synthesized and optimized with the aim of obtaining strongly hydrophilic nanomaterials, suitable as a drug delivery system (DDS) for copper-based drugs. After careful purification, AuNRs were characterized by…
Vrinzen, Stadhouders, Bloemendal et al. · 2026 · BMJ open
Concentration of care and collaborations between hospitals increasingly reorganise oncological care into Comprehensive Cancer Networks (CCNs), aiming to improve care outcomes and reduce costs. This study aims to evaluate the effect of four…
Pellerito, Dowling, Luke et al. · 2026 · Thrombosis research
Post thrombotic syndrome is a fibrotic disease related to inflammation resolution. There are no direct therapies that can ameliorate this disease. Monocyte/macrophages (Mo/MØ) are the primary leukocyte involved with later venous…
Bregen, de Buhr, Strutzberg-Minder et al. · 2026 · Veterinary sciences
The reasons for disease outbreaks caused by Actinobacillus pleuropneumoniae (APP) in vaccinated pigs are often unknown and remain a challenge for farmers and veterinarians. One hypothesis for APP vaccine failure is the timing of APP…
Wang, Ouyang, Chen et al. · 2026 · Scientific reports
This study aims to explore the impact of wearing Defocus Incorporated Multiple Segments (DIMS) spectacle lenses on astigmatism in myopic children. This study included 396 myopic children and divided the participants into two groups:the…
Ma, Qiu, Liu · 2025 · Frontiers in nutrition
Acute-on-chronic liver failure (ACLF) patients face high risks of nutritional risk and clinical complications, but whether adjuvant nutritional support reduces adverse complications remains unclear. This study included 6,097 hospitalized…
Kır · 2026 · PeerJ
This research compares the yield and quality of barley ( Hordeum vulgare ), rye ( Secale cereale ), triticale (× Triticosecale Wittmack ), and wheat ( Triticum aestivum ) grown in dry conditions in winter and widely used in producing…
Cheng, Wang, Liu et al. · 2026 · PloS one
There has been ongoing debate over whether people are intuitively honest or intuitively dishonest. A recent social harm account was proposed to address this debate: dishonesty is intuitive when cheating inflicts harm on an abstract other…