A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19830 results in Negative / Null Result Report · page 254 of 661
Garcia Campos LS, Lempert KM · 2025 · Frontiers in psychology
Introduction Uncertain decisions can be risky (with known probabilities) or ambiguous (with unknown probabilities). Previous studies have found that negative affect can increase risk aversion and ambiguity aversion, but it is unknown if…
Suberry A, Okun S, Ayalon L · 2026 · The Gerontologist
Background and objectives Ageism often emerges in childhood, yet rigorously evaluated school-based interventions-especially in multicultural settings-are scarce. The study evaluated the efficacy of a 90-min educational intervention to…
Merz LM, von Hohenberg BC, Bergmann NT et al. · 2025 · Science advances
Expanding gray wolf ( Canis lupus ) populations in Europe and North America contribute to increased risks of livestock predation, which can threaten human livelihoods and lead government agencies to target wolves for lethal removal. Public…
Seizer L, Kratzer L, Löchner J et al. · 2026 · Clinical psychology & psychotherapy
Psychotherapy process research increasingly uses intensive longitudinal monitoring to capture dynamic patterns of change in patients. In this study, 283 psychiatric inpatients diagnosed with depression (n = 70), PTSD (n = 148),…
Hauser I · 2022 · The Journal of the Acoustical Society of America
This paper reconsiders a classic claim about phonetic variability-that speech sounds in larger phonemic inventories should exhibit less within-category variability in production. Although this hypothesis is intuitive, existing literature…
Gonzalez-Nahm S, Griffith E, Maguire RL et al. · 2026 · Childhood obesity (Print)
Objective To assess the longitudinal associations between maternal diet during pregnancy and child adiposity between ages 2 and 12 years. Methods Repeated measures linear regression models with autoregressive covariance were used to assess…
Wei C, Ng VWS, Wei Y et al. · 2025 · BMC psychiatry
AIMS: Preclinical studies have suggested potential anticancer effects of valproate, but clinical evidence is limited and inconclusive. This study aims to reexamine the relationship between valproate use and cancer incidence, using lithium…
Winkelman JW, Levine MJ · 2026 · AACE endocrinology and diabetes
Type 2 diabetes mellitus is a highly prevalent metabolic disorder and a well-established risk factor for colorectal cancer (CRC), mediated by hyperglycemia, hyperinsulinemia, chronic inflammation, and obesity-related metabolic dysfunction.…
Acierno J, Tedaldi E, Ginn J et al. · 2026 · Communications psychology
Social norms have a reliable and oftentimes strong influence on individual attitudes and behaviors across environmental and other domains. This influence has been theorized to differ by cultural tightness-the extent to which people adhere…
D'Agostini M, Vanden Bossche L, Burger AM et al. · 2025 · Psychophysiology
Transcutaneous auricular vagus nerve stimulation (taVNS) has been tested as a strategy to facilitate fear extinction learning based on the hypothesis that taVNS increases central noradrenergic activity. Four studies out of six found taVNS…
· 2025 · Nature
Neutrinos are the most abundant fundamental matter particles in the Universe and play a crucial part in particle physics and cosmology. Neutrino oscillation, discovered about 25 years ago, shows that the three known species mix with each…
Xiang Y, Xu L, Sun Y et al. · 2025 · Medicine
Mobile phone use has become ubiquitous in modern life, raising public concern over its potential effects on male reproductive health. While several observational studies have reported associations between prolonged phone use and decreased…
He J, Sabroso-Lasa S, Coscia C et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background Observational studies consistently report reduced pancreatic ductal adenocarcinoma (PDAC) risk among individuals with atopic conditions (asthma and rhinitis); however, the underlying biological mechanism remains unclear. This…
Schleimer JP, Rencken CA, Wagenaar BH et al. · 2026 · JAMA network open
Importance Background checks aim to prevent illegal firearm transfers. Existing research has shown little evidence for the effect of point-of-sale comprehensive background check (CBC) policies on firearm-related violence at the state…
Nielsen SP, Mathiesen L, Moller P · 2024 · Preprint
not-yet-known not-yet-known not-yet-known unknown Abstract This review examines the association between early life exposure to phthalates in human males and Leydig cell endocrine function. A systematic search was performed in PubMed and…
Walda SAE, van Weerdenburg M, Bosman AMT · 2024 · Research in developmental disabilities
Background Poor decoding and spelling (literacy) skills have been associated with weak working memory. Aims The aim of this study was to elucidate the contribution of working memory to literacy progress in students with dyslexia. It has…
Bertoldi AD, Flores TR, Silveira MPT et al. · 2026 · Ciencia & saude coletiva
This study aimed to investigate the association between the use of antimicrobials during pregnancy and excess weight in children at ages three, 12, 24 and 48 months. Data of participants from the 2015 Pelotas (Brazil) Birth Cohort study…
Hiredesai AN, Martinez CJ, Hinckley NB et al. · 2026 · Cureus
Purpose Shear wave elastography (SWE) is a non-invasive technique for assessing median nerve (MN) stiffness in carpal tunnel syndrome (CTS). This study evaluated whether SWE measurements of the MN improve after corticosteroid injection…
Pater WJ, Buller LT, Ziemba-Davis M et al. · 2026 · Arthroplasty today
Background Tourniquet use in revision total knee arthroplasty (rTKA) enhances visualization and improves cement penetration. However, concerns exist about muscle injury, pain, wound complications, and venous thromboembolism (VTE). This…
Gao S, Gross AL, Aksman LM et al. · 2026 · Journal of Alzheimer's disease : JAD
BackgroundPlasma neurodegenerative biomarkers are a potential low-cost tool for studying Alzheimer's disease and dementia in population-based research, especially in low- and middle-income countries. However, their associations with…
Atkinson A, Marschall J, Burnham JP · 2025 · Antimicrobial resistance and infection control
Background Air changes per hour (ACH) in operating rooms (ORs) are energy intensive, and optimal air change settings are not known. Objectives We sought to explore whether there is a relationship between surgical site infections (SSIs)…
Perales-Puchalt J, Yang FM, Townley R · 2025 · Alzheimer disease and associated disorders
We tested the efficacy of docosahexaenoic acid (DHA) supplementation on aggressive behavior among people with dementia. We used secondary data from a randomized, double-blind, placebo-controlled trial. Analyses included 402 individuals…
Sheng Y, Han Y, Xue Y · 2026 · Medicine
Beta-blockers are recommended for post-myocardial infarction (MI) care, but their long-term impact on all-cause mortality in real-world settings remains unclear. This study investigates the association using propensity score methods in a…
Watkins K, Ladabaum U, Olsen E et al. · 2024 · iGIE : innovation, investigation and insights
Background and aims The progress of artificial intelligence (AI) in endoscopy is at a crossroads. The positive results of randomized controlled trials of computer-aided detection (CADe) have not been replicated in multiple pragmatic CADe…
Kusztor A, Mulay N, Yamada M et al. · 2025 · Neuroscience of consciousness
During an acute episode of depersonalization/derealization (DP/DR), people report a complex and idiosyncratic change in their perceptual experience. Specifically, derealisation describes the experience of detachment from the external world…
Raut U · 2023 · Preprint
The formation of mini black holes is now considered to be an inescapable consequence of TeV scale particle collision scenarios in extra-dimensional/ADD models. Furthermore, such mini black holes have been predicted to be produced at…
Beaver JN, Nicodemus MM, Spalding IR et al. · 2025 · eNeuro
Mice offer a wealth of opportunities for investigating brain circuits regulating multiple behaviors, largely due to their genetic tractability. Social behaviors are translationally relevant, considering both mice and humans are highly…
Kraft VM, Jones DR, Smyth JM et al. · 2026 · Emotion (Washington, D.C.)
Variability in daily emotional experiences may be important for both mental and physical health and may be influenced by individual differences such as age, gender, race, and ethnicity. Research on individual differences in affect…
Coppeto DJ, Martin JS, Ringen EJ et al. · 2024 · Peptides
The neurohormones oxytocin (OT) and arginine vasopressin (AVP) are involved in social behaviors and psychiatric conditions. However, more research on nonhuman primates with complex social behaviors is needed. We studied two closely-related…
Shapouri S, Rafiee Y · 2024 · Human nature (Hawthorne, N.Y.)
Considering the role of human interactions in infectious disease outbreaks and cooperation in mitigating natural disasters consequences, ecological threats to human survival have been among proposed drivers of collectivism. Utilizing…