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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19830 results in Negative / Null Result Report · page 253 of 661

Negative / Null Result Report

The influence of verbalization versus imagery on trauma memory

Rupietta AE, Meyer T, Margraf J et al. · 2026 · Preprint

Background: Cognitive theories on trauma memory postulate that trauma-related intrusions are associated with more data-driven and less contextual processing. However, contextualisation can be enhanced via verbalization, suggesting that…

View details →DOI: 10.31234/osf.io/tcsre_v4
Negative / Null Result ReportMedicine

Evaluation of Short-Term Stall Size Housing on the Behavior and Welfare of Domestic Horses (Equus caballus).

Outouil M, Daugherity EK, Warnick LD et al. · 2026 · Journal of the American Association for Laboratory Animal Science : JAALAS

Single-stall housing is a common system used for horses in various settings, including racing stables, riding schools, teaching and research facilities. Adequate stall space is necessary for horses to lie down and make postural…

View details →DOI: 10.30802/aalas-jaalas-25-152
Negative / Null Result Report

The insect- and plant-associated lifestyles of Pseudomonas protegens CHA0 are preserved following serial passage through insect larvae

Zwyssig M, Schneider J, Selten G et al. · 2026 · Preprint

The plant-beneficial bacterium Pseudomonas protegens CHA0 (CHA0) is widely studied for the biological control of soil-borne plant diseases. Beyond its root-colonising capabilities, CHA0 can also infect and kill insect larvae and thus…

View details →DOI: 10.64898/2026.03.19.712869
Negative / Null Result ReportMedicine

Three Decades of Evidence on Pulsatile Cardiopulmonary Bypass in Pediatrics: No Significant Clinical Benefit.

Ündar A, Lussier MJ, Rajesh S et al. · 2026 · World journal for pediatric & congenital heart surgery

BackgroundDrawing on more than 30 years of valuable expertise in in-vitro, in-vivo, and clinical trials, we report the key findings of our institutional research on pulsatile cardiopulmonary bypass (CPB).MethodsA detailed search was…

View details →DOI: 10.1177/21501351251412887
Negative / Null Result ReportOpen accessMedicine

Impact of adding a medical intern to the emergency department night shift.

Glass-Biran AH, Eyre A, Stein G et al. · 2026 · BMJ open quality

Objective To evaluate whether adding a fourth physician to the emergency department night shift would improve metrics. Methods This retrospective cohort study used data from the Meir Medical Centre emergency department, 1 January 2021 to…

View details →DOI: 10.1136/bmjoq-2025-003648
Negative / Null Result ReportMedicine

Evaluation of an Immune-guided Prevention Strategy Against CMV Among Intermediate-risk Kidney Transplant Recipients: A Quasi-experimental Study.

Caso JM, Fernández-Ruiz M, González E et al. · 2026 · Transplantation

Background Observational studies have shown that kidney transplant (KT) recipients who are cytomegalovirus (CMV)-seropositive (R+) but lack effective CMV-specific cell-mediated immunity (CMV-CMI) are at increased risk of CMV infection.…

View details →DOI: 10.1097/tp.0000000000005694
Negative / Null Result ReportOpen accessMedicine

Evaluating the role of high-dose intravenous thiamine supplementation for lactate clearance in patients with cirrhosis and sepsis.

Ali R, Yazdi A, Collins K et al. · 2026 · International journal of critical illness and injury science

Background Thiamine is a vitamin that plays a role in lactate clearance. Patients with sepsis may present with elevated lactate, and also in cirrhosis, as lactate is hepatically metabolized. Prior studies showed mixed results regarding the…

View details →DOI: 10.4103/ijciis.ijciis_124_25
Negative / Null Result ReportMedicine

Euschistus heros RNase silencing: dsRNA stability and effects on RNAi susceptibility.

Quiroga-Murcia DE, Dos Santos ÉA, Schutter K et al. · 2025 · Journal of insect physiology

Nuclease (RNase) activity is a major limiting factor that reduces the effectiveness of RNAi-induced gene silencing across many insect species. In Euschistus heros, dsRNA degradation occurs predominantly upon contact with saliva, while…

View details →DOI: 10.1016/j.jinsphys.2025.104908
Negative / Null Result ReportMedicine

Transforming extracted cashew nut shell into biochar and its application as soil amender for jute mallow (Corchorus olitorius L.) cultivation.

Alaka MO, Ogunjobi JK, Omoruyi OE et al. · 2026 · Scientific reports

This study addresses the environmental challenges posed by the waste generated during the extraction of cashew nut shell (CNS) liquid by proposing a sustainable repurposing method. Extracted CNS (waste) was pyrolyzed at varying…

View details →DOI: 10.1038/s41598-026-35559-6
Negative / Null Result ReportMedicine

The influence of verbalization versus imagery on trauma memory.

Rupietta AE, Meyer T, Margraf J et al. · 2026 · Journal of behavior therapy and experimental psychiatry

Background Cognitive theories on trauma memory postulate that trauma-related intrusions are associated with more data-driven and less contextual processing. However, contextualisation can be enhanced via verbalization, suggesting that…

View details →DOI: 10.1016/j.jbtep.2026.102088
Negative / Null Result ReportMedicine

Response of juvenile Chinook salmon (Oncorhynchis tshawytscha) to the aquatic herbicide florpyrauxifen-benzyl.

Grue C, Getsinger KD, Heilman MA et al. · 2026 · Environmental toxicology and chemistry

Florpyrauxifen-benzyl (aquatic tradename ProcellaCOR) is an aquatic herbicide commonly used to control Eurasian watermilfoil (Myriophyllum spicatum) and other invasive aquatic plants. Previous studies have demonstrated effective Eurasian…

View details →DOI: 10.1093/etojnl/vgaf273
Negative / Null Result ReportMedicine

Safety, Immunogenicity of Co-Administered Vaccines, and Lot-to-Lot Consistency of a 14-Valent Pneumococcal Conjugate Vaccine (PNEUBEVAX 14<sup>®</sup>) Administered at 6-10-14 Weeks in Healthy Infants: A Multicenter, Phase IV Trial.

Thuluva S, Gunneri S, Ningaiah S et al. · 2026 · Vaccines

Background: Pneumococcal conjugate vaccines (PCVs) have substantially reduced pneumococcal disease in children; however, serotype distribution varies geographically, and residual disease due to non-PCV13 serotypes persists. Biological E's…

View details →DOI: 10.3390/vaccines14060464
Negative / Null Result ReportMedicine

DNA recovery from 3D printed firearms.

Oltrogger FT, Howe G, McNevin D et al. · 2026 · Science & justice : journal of the Forensic Science Society

Over the last few years, additive manufacturing, by means of fused deposition modelling 3D printing, has become increasingly popular and accessible due to the relative low costs, flexibility, and continually lowering barriers for entry.…

View details →DOI: 10.1016/j.scijus.2026.101409
Negative / Null Result ReportMedicine

Beyond Gram-Negative and Gram-Positive Bacteria: Virulence as a Determinant of Clinical Outcome in Periprosthetic Joint Infections.

Achatz V, Sebastian S, Mitterer JA et al. · 2026 · The Journal of arthroplasty

Background Gram-negative (GN) periprosthetic joint infections (PJIs) are still less frequent than gram-positive (GP) PJIs. There is only little data available on a direct comparison of GP- and GN-associated PJIs. Therefore, we investigated…

View details →DOI: 10.1016/j.arth.2026.02.031
Negative / Null Result ReportMedicine

Natural versus GnRHa-HRT cycle for FET in tubal infertility with prior failed natural cycles: a propensity score-matched retrospective cohort study.

Li L, Gao S, Zhu H et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology

Introduction Frozen embryo transfer offers improved cumulative pregnancy rates and reduces complications compared to fresh cycles. Successful outcomes depend on both embryonic potential and endometrial receptivity, necessitating…

View details →DOI: 10.1016/j.ejogrb.2026.115194
Negative / Null Result ReportMedicine

The Effect of Contrast Media Formulations with Different Iodine Preparation Concentrations at a Constant Iodine Delivery Rate in Low-kV CT Angiography: An Experimental Animal Study.

Holtkamp M, Jost G, Salhöfer L et al. · 2026 · RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

Purpose The effect of iodine preparation concentration on vascular attenuation during computed tomography angiography (CTA) is a topic of controversy. Iodine-based contrast media (CM) formulations are used in different iodine preparation…

View details →DOI: 10.1055/a-2818-5244
Negative / Null Result ReportMedicine

Light at the End of the Tunnel! Effects of 405 nm Visible Light Disinfection on Surgical Site Infection: A Prospective Randomized Cohort Study.

Bauerle WB, Allsbrook A, Green A et al. · 2026 · Surgical infections

Introduction Surgical site infections (SSIs) are a substantial contributor to morbidity and mortality rates. 405 nm visible light disinfection (VLD) has been shown to reduce bacterial burden in operating rooms (ORs); however, its effect on…

View details →DOI: 10.1177/10962964251410006
Negative / Null Result ReportOpen accessMedicine

Dimensional Stability of SLA 3D-Printed Surgical Guide Resin After Steam Sterilization (121 °C and 134 °C) and Isopropyl Alcohol Disinfection: An In Vitro Study.

Sîrbu I, Custura A, Radu A et al. · 2026 · Dentistry journal

Background : Additively manufactured surgical guides require post-processing and subsequent decontamination prior to intraoral use. Steam sterilization and chemical disinfection protocols may influence the dimensional stability of…

View details →DOI: 10.3390/dj14040204
Negative / Null Result Report

The influence of verbalization versus imagery on trauma memory

Rupietta AE, Meyer T, Margraf J et al. · 2025 · Preprint

Background: Cognitive theories on trauma memory postulate that trauma-related intrusions are associated with more data-driven and less contextual processing. However, contextualisation can be enhanced via verbalization, suggesting that…

View details →DOI: 10.31234/osf.io/tcsre_v2
Negative / Null Result ReportMedicine

Effects of hypocaloric wholegrain rye vs refined wheat diets on weight loss, cardiometabolic risk factors and gut microbiota: A 12-week randomized controlled trial.

Åberg S, Nordin E, Iversen KN et al. · 2026 · Clinical nutrition (Edinburgh, Scotland)

Background and aims Wholegrain rye foods have shown promising effects on metabolic regulation and weight-loss, which may be mediated via gut microbiota and derived metabolites. This study aimed to investigate effects of hypocaloric diets…

View details →DOI: 10.1016/j.clnu.2026.106618
Negative / Null Result ReportMedicine

Stability strategy restrictions do not elicit compensatory mechanisms during mediolaterally perturbed slow walking.

Best AN, Vlutters M, Wu AR · 2025 · IEEE transactions on bio-medical engineering

Objective Healthy individuals have the ability to overcome perturbations when walking without falling. They have multiple stability strategies at their disposal, but it remains unclear how these different strategies compensate for one…

View details →DOI: 10.1109/tbme.2025.3630549
Negative / Null Result ReportMedicine

Transmucosal detomidine gel induces emesis in approximately half of cats presenting for dietary indiscretion.

Neufeld MR, Hanson KR, Mochel JP et al. · 2026 · Journal of the American Veterinary Medical Association

Objective To evaluate the efficacy and safety of transmucosal administration of detomidine gel to induce emesis in cats. Methods Cats presenting on an emergency basis due to dietary indiscretion were eligible for enrollment at 2 emergency…

View details →DOI: 10.2460/javma.25.10.0644
Negative / Null Result ReportOpen accessMedicine

Unplanned hospital presentations in oncology patients receiving chemotherapy: a secondary analysis of a randomized controlled trial to explore opportunities for improving supportive care.

Kim B, Boustany C, Fethney J et al. · 2026 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Purpose This study aimed to report the incidence, common reasons, and associated risk factors for unplanned hospital presentations during chemotherapy treatment. Methods A secondary analysis using data from a randomized controlled trial…

View details →DOI: 10.1007/s00520-026-10510-7