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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20227 results in Negative / Null Result Report · page 252 of 675

Negative / Null Result ReportOpen accessMedicine

Novel Taiwan-I-type infectious bronchitis virus: First evidence of testicular atrophy and efficacious protection with strain-matched oil-emulsified inactivated vaccine.

Zhang T, Xie Y, Yang C et al. · 2026 · Virulence

The Taiwan-I-type infectious bronchitis virus (IBV) has become one of the most dominant and threatening genotypes circulating in China poultry farms. In this study, we characterized the Taiwan-I-type IBV strain GX-NN200723 and evaluated…

View details →DOI: 10.1080/21505594.2026.2664950
Negative / Null Result ReportOpen accessMedicine

A comparative evaluation of apical sealing ability of NeoPutty, Biodentine, and Bio-c repair using a radioactive isotope method - An <i>in vitro</i> study.

Rathore S, Bhushan J, Uppal AS et al. · 2026 · Journal of conservative dentistry and endodontics

Background Treatment of teeth with immature apices is difficult to manage by conventional endodontics. Apical barrier formation using bioceramic materials offers a biologically favorable solution, providing a hermetic seal that supports…

View details →DOI: 10.4103/jcde.jcde_97_26
Negative / Null Result ReportMedicine

Comparison of Dexamethasone versus Ondansetron for Postoperative Nausea and Vomiting in Laparoscopic Cholecystectomy.

Loomba P, Nayak M, Podder S et al. · 2026 · Annals of African medicine

Background Postoperative nausea and vomiting (PONV) are a prevalent complication after laparoscopic surgeries, with an incidence reaching up to 63% without antiemetic prophylaxis. Objectives To evaluate the efficacy of dexamethasone and…

View details →DOI: 10.4103/aam.aam_60_26
Negative / Null Result ReportMedicine

The Effect of Virtual Simulation of Parenteral Medication Administration on Nursing Students' Knowledge and Skills: A Randomized Controlled Experimental Study.

Biyik Bayram S, Gülnar E, Çalişkan N et al. · 2026 · Computers, informatics, nursing : CIN

This study investigated the effect of virtual simulation of parenteral medication administrations on nursing students' knowledge and skills. This randomized controlled experimental study adopted a pretest-posttest research design. The…

View details →DOI: 10.1097/cin.0000000000001581
Negative / Null Result ReportOpen accessMedicine

Evaluation of Time-Dependent Chemical Alterations in Sodium Hypochlorite Solution Kept on the Unit Tray During an Average Root Canal Treatment Period.

Bastug Guven E, Genc Sen O · 2026 · Medical science monitor : international medical journal of experimental and clinical research

BACKGROUND Sodium hypochlorite (NaOCl) is the most commonly used irrigant in root canal treatment because of its antimicrobial activity and tissue-dissolving capacity. Since these properties are related to its physicochemical…

View details →DOI: 10.12659/msm.952416
Negative / Null Result ReportOpen accessMedicine

Safety and Efficacy of Stereotactic Body Radiation Therapy in Very Elderly Patients (≥80 Years) with Solitary Hepatocellular Carcinoma.

Tamura Y, Tojima H, Takizawa D et al. · 2026 · Cancers

Background The number of elderly patients with hepatocellular carcinoma (HCC) has been increasing worldwide. This study aimed to evaluate the clinical outcomes of stereotactic body radiation therapy (SBRT) for patients aged ≥80 years with…

View details →DOI: 10.3390/cancers18111809
Negative / Null Result ReportOpen accessMedicine

Impact of hyperbaric oxygen as initial treatment on idiopathic sudden sensorineural hearing loss prognosis: a propensity scores matching analysis.

Xie S, Hong W, Huang L et al. · 2026 · Brazilian journal of otorhinolaryngology

Objective This study aimed to evaluate the effect of Hyperbaric Oxygen Therapy (HBOT) combined with steroids as initial treatment on the prognosis of patients with Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL) by using propensity…

View details →DOI: 10.1016/j.bjorl.2026.101775
Negative / Null Result ReportOpen accessMedicine

Research on the intervention of Mandala drawing therapy for social interaction disorders in children with autism.

Zhang L, Luo L, Xia Q et al. · 2026 · Frontiers in psychiatry

Social communication disorder is a core impairment in children with Autism Spectrum Disorder (ASD) and is essential for establishing connections with the external world. This study aimed to explore the effects of Mandala drawing therapy on…

View details →DOI: 10.3389/fpsyt.2026.1757575
Negative / Null Result ReportOpen accessMedicine

Effects of Norbixin on Growth Performance, Immunomodulation, Antioxidant Systems, and Metabolic Alterations in the Oriental River Prawn (Macrobrachium nipponense): An Integrative Analysis.

Ettefaghdoost M, Haghighi H, Haghdoost A · 2026 · Veterinary medicine and science

Background Natural carotenoids have gained considerable attention in aquaculture due to their potential to enhance growth performance, physiological status, and product quality in crustaceans. However, limited information is available…

View details →DOI: 10.1002/vms3.71014
Negative / Null Result ReportMedicine

The Effect of Education Through Interactive Videos on Noninvasive Blood Pressure Measurement Knowledge and Skill Level of Nursing Students.

Can Ş, Eren H · 2026 · Computers, informatics, nursing : CIN

Measuring noninvasive blood pressure (NIBP) is a fundamental skill that nursing students are trained to master, and they are expected to possess comprehensive knowledge and proficiency in this procedure to ensure accurate measurements. The…

View details →DOI: 10.1097/cin.0000000000001582
Negative / Null Result ReportOpen accessMedicine

Identical versus compatible blood typing: investigating best practices in lung transplantation.

Bugacov H, Cusmai C, Li K et al. · 2026 · Transplant international : official journal of the European Society for Organ Transplantation

This study investigated acute rejection in ABO-compatible versus ABO-identical lung transplants from 2005-2023, with a secondary objective of comparing 5-year survival. Lung transplantation improves quality of life and survival; however,…

View details →DOI: 10.3389/ti.2026.15722
Negative / Null Result ReportMedicine

The effect of midwife-led education based on Pender's health promotion model (MidLed-PHPM) on the perinatal mental health of immigrant women.

Cevik A, Alan S · 2026 · Women and birth : journal of the Australian College of Midwives

Background Perinatal mental health issues are a global problem that constitutes a significant part of the burden on maternal and infant health. This situation could pose a risk, especially for immigrant women, who are a vulnerable group.…

View details →DOI: 10.1016/j.wombi.2026.102213
Negative / Null Result ReportOpen accessMedicine

Physical performance responses to match venue and outcome in elite soccer.

Nobari H, Kamis O, Atıcı AR et al. · 2026 · BMC sports science, medicine & rehabilitation

Background It is widely accepted that match venue influences technical, tactical, fitness, nutrition, the importance of the match, sleep, and psychological factors. This study investigates the impact of match venue (i.e., home vs. away)…

View details →DOI: 10.1186/s13102-026-01723-8
Negative / Null Result ReportOpen accessMedicine

Effects of MDMA treatment and cessation on sexual behaviour and testicular functions in male sprague-dawley rats.

Obembe OO, George ET, Mustapha RA et al. · 2026 · BMC pharmacology & toxicology

BACKGROUND: 3,4-Methylenedioxymethamphetamine (MDMA) is a psychostimulant known for its social and empathogenic effects. However, its long-term impact on sexual performance and reproductive functions remain controversial. OBJECTIVE: In…

View details →DOI: 10.1186/s40360-026-01131-1
Negative / Null Result Report

Analysis of the effect of vertebroplasty via kambin's triangular approach in the treatment of spinal deformity with vertebral compression fracture

Jiang Z, Tan X, Zhang M et al. · 2026 · Preprint

Abstract Objective : To explore the clinical efficacy of percutaneous vertebroplasty (PVP) via Kambin's triangle in the treatment of senile spinal deformity accompanied by vertebral compression fractures. Methods : A retrospective analysis…

View details →DOI: 10.21203/rs.3.rs-9403084/v1
Negative / Null Result ReportOpen accessMedicine

A Comparison of Monoaxial Pedicle Screws Versus Polyaxial Pedicle Screws in Posterior Fusion Surgery for Adolescent Idiopathic Scoliosis (Lenke Type 1).

Hammad A, Saleh ME, Shehab AA · 2026 · Cureus

Background Adolescent idiopathic scoliosis (AIS) is the most common form of spinal deformity in adolescents, characterized by a three-dimensional curvature of the spine with unknown etiology. Surgical intervention is indicated in…

View details →DOI: 10.7759/cureus.107673
Negative / Null Result ReportOpen accessMedicine

Effects of music during endoscopy on pain, anxiety and vital signs: a randomized controlled study.

Bozkurt SN, Kocasli S · 2026 · BMC complementary medicine and therapies

AIMS: The aim of this study was to the effects of music during the endoscopy procedure on anxiety, pain and vital signs. METHODS: This study was conducted as a randomized, controlled, double-blind trial. The study population consisted of…

View details →DOI: 10.1186/s12906-026-05381-8
Negative / Null Result ReportOpen accessMedicine

Quantifying glenoid bone loss in the setting of primary reverse shoulder arthroplasty.

MacFarlane AJ, Larson JH, Kucharik MP et al. · 2026 · Journal of shoulder and elbow arthroplasty

Background Presently, there is no quantifiable and objective criteria for defining severe glenoid bone loss (GBL) for primary reverse total shoulder arthroplasty (rTSA). In this study, we sought to establish quantifiable thresholds of…

View details →DOI: 10.1016/j.jsea.2026.100015
Negative / Null Result ReportOpen accessMedicine

Prognostic Value of Combined Neutrophil-to-Lymphocyte Ratio and Prognostic Nutritional Index in Advanced Ovarian Cancer Treated With Neoadjuvant Chemotherapy.

Ishida H, Egashira H, Asano N et al. · 2026 · Cureus

Background Inflammation- and nutrition-related biomarkers such as the neutrophil-to-lymphocyte ratio (NLR) and prognostic nutritional index (PNI) have been reported as prognostic factors for ovarian cancer. However, their clinical…

View details →DOI: 10.7759/cureus.108250
Negative / Null Result ReportMedicine

Effect of remazolam combined with hydromorphone postoperative analgesia on cognitive function in elderly patients undergoing hip replacement.

Zheng X, Fu X, Shao Y et al. · 2026 · American journal of translational research

Objective To investigate the effect of remazolam combined with hydromorphone on postoperative cognitive function in elderly patients undergoing hip replacement. Methods 184 elderly patients who underwent hip replacement in Sir Run Run Shaw…

View details →DOI: 10.62347/tfej7525
Negative / Null Result Report

Under-correction is not advisable in valgus knee and lateral approach is more feasible than medial approach to achieve this: A 5-year follow-up study

Li S, Chai H, Bao W et al. · 2026 · Preprint

Abstract Background: It is commonly recommended to restore the mechanical axis to within –0° ± 3° in valgus knee. However, the situation is quite different when the alignment is –3° or 3° in the presence of a compromised MCL in Ranawat…

View details →DOI: 10.21203/rs.3.rs-9715753/v1
Negative / Null Result ReportOpen accessMedicine

Effects of ultrasound-assisted tumbling on physicochemical properties, myofibrillar protein structure, and protein oxidation during beef curing.

Jin L, Zhang J, Zhang R et al. · 2026 · Ultrasonics sonochemistry

The aim of this study was to investigate the effects of ultrasound-assisted tumbling (100, 300, 500, and 700 W) with different treatment times (30, 60, 90, 120, 150, and 180 min) on the quality, myofibrillar protein structure, and protein…

View details →DOI: 10.1016/j.ultsonch.2026.107919
Negative / Null Result ReportOpen accessMedicine

Effectiveness of Acupressure on Anxiety, Fatigue, and Sleep Quality Among Operating Room Personnel: A Randomized Controlled Trial.

Abjar R, NasiriFormi E, Kazemi AH et al. · 2026 · Health science reports

Background and aims High-quality sleep, calmness, and lack of fatigue are vital for the health of critical hospital staff. Operating room personnel experience significant mental and physical stress, including anxiety and sleep…

View details →DOI: 10.1002/hsr2.72680
Negative / Null Result Report

Association of Primary Nocturnal Enuresis with Renal Parenchymal Thickness: Insights from a Study on Enuresis Prevalence and Related Factors

Merikhi A, Gheisari A, Kasiri P et al. · 2026 · Preprint

Abstract Background: Nocturnal Enuresis (NE), characterized by the inability to control nighttime voiding in children above five years, is one of the common problems faced by the young generation today and can result in some psychological…

View details →DOI: 10.21203/rs.3.rs-9818630/v1
Negative / Null Result ReportMedicine

<i>Invitro</i> Hepatic like Differentiation of Umbilical Cord-Derived Mesenchymal Stem Cells through FGF and IGF Factor Preconditioning.

Zahid Habib Q, Tahir M, Bakhtawar F et al. · 2026 · Journal of stem cells & regenerative medicine

Introduction Liver diseases remain a major global health burden, with limited treatment options for advanced hepatic dysfunction. Current treatment options are limited and mainly supportive, with liver transplantation being the only…

View details →DOI: 10.46582/jsrm.2201004
Negative / Null Result ReportMedicine

Helicobacter pylori infection carrying the CagA gene may be associated with the diagnosis and disease progression of tuberculosis.

Huang F, Zhan H, Yang Y et al. · 2026 · BMC infectious diseases

Background and objective Helicobacter pylori (H. pylori) infection is associated with infectious diseases caused by pathogens such as Orientia tsutsugamushi (the causative agent of scrub typhus) and Brucella. However, the impact of H.…

View details →DOI: 10.1186/s12879-026-13491-4
Negative / Null Result ReportOpen accessMedicine

Evaluation of the Advantages of Silicone Stent in Revision Endoscopic Dacryocystorhinostomy in a Tertiary Care Hospital.

Sonawane C, Raval RR, Bajaj A et al. · 2026 · International archives of otorhinolaryngology

Introduction Silicone stents are often employed in dacryocystorhinostomy (DCR) procedures to maintain the patency of the newly created tear drainage passage during the healing stage. These stents are flexible, biocompatible, and generally…

View details →DOI: 10.1055/s-0046-1818565
Negative / Null Result ReportOpen accessMedicine

The effect of timing on rehabilitation results in tumor-related spinal cord injuries.

Yorulmaz E, Geler-Kulcu D, Ramazanoglu AF et al. · 2026 · Turkish journal of physical medicine and rehabilitation

Objectives This study aims to investigate the impact of early initiated rehabilitation on outcomes in patients with spinal cord injuries related to tumors. Patients and methods In this retrospective cohort study conducted between January…

View details →DOI: 10.5606/tftrd.2026.17637
Negative / Null Result ReportOpen accessMedicine

Acute Effect of Percussive Massage on Cross-Section Area, Muscle Strength, and Late Muscle Pain of the Quadriceps Muscle Following a Fatigue Protocol in Physically Active Men: Randomized Clinical Trial.

da Rosa Castilho A, Aguiar AF, Ribeiro AS et al. · 2026 · Physiotherapy research international : the journal for researchers and clinicians in physical therapy

Background and purpose The massage gun is widely used to alleviate delayed-onset muscle soreness (DOMS); however, empirical evidence regarding its physiological effects remains limited. Objectives This study aimed to evaluate the acute…

View details →DOI: 10.1002/pri.70246