A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20227 results in Negative / Null Result Report · page 251 of 675
Tsiotsios, Vamvakas, Labropoulou et al. · 2026 · Acta haematologica
Introduction Patients with homozygous β-thalassemia show continuously improved survival, which has contributed to the development of kidney complications, predominantly expressed as increased albuminuria. In particular, patients with…
Npochinto Moumeni, Dikongue · 2026 · Frontiers in pediatrics
Delayed presentation of pediatric musculoskeletal trauma remains a critical yet underexplored challenge in sub-Saharan Africa, where cultural beliefs, socioeconomic constraints, and reliance on traditional healing practices frequently…
de Azevedo Ferreira, Fitz, Gimenez et al. · 2026 · International urogynecology journal
Seventy percent of women with pelvic floor muscle (PFM) dysfunction are unable to contract these muscles correctly. Instruction to contract properly is essential for effective PFM training (PFMT). The study aimed to compare two…
Park, Park, Song et al. · 2026 · Analytical and bioanalytical chemistry
Real-time quantification of individual amino acids in mammalian cell culture using Raman spectroscopy remains challenging due to significant spectral overlaps and reliance on empirical regression chemometrics. Presented herein is Raman…
Gilad, Jacover, Levy et al. · 2026 · Pediatric cardiology
Furosemide resistance and fluid overload remain major challenges in postoperative pediatric cardiac patients. Although adult studies suggest synergistic effects of hypertonic saline with loop diuretics, pediatric postoperative physiology…
Roganović, Zubović, Đorđević et al. · 2026 · Acta medica academica
To analyze the characteristics, etiology, diagnostic evaluation, management, follow-up, and outcomes of children with chronic neutropenia treated at a tertiary care pediatric hospital in Croatia. We retrospectively reviewed the…
Hardy, Hibbert, Tasker et al. · 2026 · Journal of feline medicine and surgery
To determine the frequency and clinical significance of discordant serum symmetric dimethylarginine (SDMA) and creatinine concentrations relative to glomerular filtration rate (GFR) in mature and senior hyperthyroid cats treated with…
Flavin, Vernon, Todd Cade et al. · 2026 · Journal of managed care & specialty pharmacy
Barth syndrome is an ultrarare, complex, multisystem, X-linked metabolic and neuromuscular disease, which poses significant and wide-ranging burden to patients and caregivers. Pharmacologic management focuses on treatment of disease…
Ani, Hameed · 2026 · Wiadomosci lekarskie (Warsaw, Poland : 1960)
Aim: This study aimed to evaluate the effectiveness of a structured intravenous infusion protocol in improving the quality of care and reducing IV-related complications among hospitalized patients. Materials and Methods: A purposive sample…
Wang, Leng · 2026 · The Journal of international medical research
ObjectiveAlthough renal failure is an important cause of death in the United States, recent mortality trends and subgroup differences remain insufficiently characterized. This nationwide ecological time-trend study examined renal failure…
Kim, Park, Park et al. · 2026 · American journal of physical medicine & rehabilitation
Lumbosacral radiculopathy often presents as back pain and lower limb weakness and is frequently encountered in rehabilitation medicine. Fibrocartilaginous embolism (FCE) is an uncommon but significant vascular cause of radiculopathy. It…
Peake, Swirbul, Rodio et al. · 2026 · Frontiers in digital health
Consistent client engagement with between-therapy session activities (i.e., homework) is a strong predictor of positive psychotherapy outcomes. Because traditional homework activities aren't always tailored to the individual, they can fail…
Jain, Kamboj, Sakale · 2026 · Journal of clinical orthopaedics and trauma
Hip preservation surgery (HPS) is increasingly performed in young and active patients with the aim of delaying or avoiding total hip arthroplasty (THA). Despite advances in preservation techniques, a proportion of patients eventually…
Zhao, Ma, Mo et al. · 2026 · Frontiers in medicine
To investigate the status of missed nursing care and examine the mediating role of calling between nursing work environment and missed nursing care. Missed nursing care (MNC) critically affects patient safety and care quality and is…
Alqannas, Taha, Abuabed et al. · 2026 · Frontiers in medicine
Mental healthcare providers (MHPs) face high burnout due to emotional demands and workload pressures. In Jordan, limited resources and public stigma may further increase occupational strain, underscoring the need to assess burnout among…
Yang, Lu · 2026 · Open medicine (Warsaw, Poland)
Portal venous gas (PVG) is commonly associated with severe gastrointestinal disease, whereas benign causes related to endoscopic procedures are uncommon. We report an unusual mechanism of PVG occurring in the setting of chronic gastric…
Lu, Bi, Gao et al. · 2026 · Frontiers in cellular and infection microbiology
Electroacupuncture (EA) serves as an effective complementary therapy in the treatment of inflammatory bowel disease (IBD) within traditional Chinese medicine, with the therapeutic efficacy significantly influenced by the selection of…
Chilundo, Xinavane, Huo et al. · 2026 · Frontiers in reproductive health
Despite national policies promoting adolescent- and youth-friendly health services, implementation gaps hinder improvements in adolescent sexual and reproductive health outcomes in Mozambique. S-NICE is a structured, participatory…
Zhou, Wang, He et al. · 2026 · JACS Au
DNA origami placement (DOP) exploits shape complementarity between DNA nanostructures and lithographically patterned binding sites to achieve precise spatial positioning, offering a promising route for integrating bottom-up self-assembly…
Boettger, Sedighi, Pallmann et al. · 2026 · Journal of the Intensive Care Society
Thyroid hormone alterations are common in critical illness and may reflect disease severity. Their prognostic significance in infarct-related cardiogenic shock remains incompletely defined. In this prospective cohort study from a…
Argaw, Jingili, Oyelere et al. · 2026 · JMIR XR and spatial computing
Anxiety-related symptoms are prevalent and can negatively affect concentration, motivation, and overall well-being. Traditional treatments such as cognitive behavioral therapy and medication work well for clinical anxiety disorders.…
Sheikh, Singh, Smith et al. · 2026 · Frontiers in cardiovascular medicine
The impact of catheter-directed thrombolysis (CDT), catheter-directed embolectomy (CDE) and surgical pulmonary embolectomy (SPE) on long term RV function among patients with acute PE remains unclear. We investigated the association of…
Elmansy, Elbqry, Qalawa et al. · 2026 · Frontiers in nutrition
Hemodialysis is a life-sustaining renal replacement therapy that removes metabolic waste products normally eliminated by the kidneys. Patients undergoing hemodialysis are required to adhere to strict fluid and dietary restrictions to…
Lin, Yu, Hu et al. · 2026 · Precision radiation oncology
The optimal management of locally advanced resectable esophageal squamous cell carcinoma (ESCC), particularly for cT3-4a disease, remains debated. This study aimed to compare the survival outcomes and toxicity profiles of neoadjuvant…
Kawakita, Hayasaka, Barake et al. · 2026 · Pregnancy (Hoboken, N.J.)
Prenatal phthalate exposure is linked to adverse reproductive and developmental outcomes and is consistently higher among non-Hispanic Black compared to non-Hispanic White pregnant individuals, yet the factors responsible for these…
Tilahun, Urge, Girma et al. · 2026 · Veterinary and animal science
The current study evaluated the effects of black cumin seed meal (BCSM) on growth performance, cecal microbiota, production efficiency, and cost efficiency in broiler chickens. A total of 144 one-day-old unsexed Cobb 500 broiler chicks…
Navidifar, Kaveh, Hosseini et al. · 2026 · Veterinary and animal science
Efficient estrus synchronization is important for improving reproductive performance in dairy herds; however, variations in ovarian activity among cows of different parities may influence responses to synchronization protocols. The present…
Naizabayev, Talgatov, Auyezkhanova et al. · 2026 · Molecules (Basel, Switzerland)
Palladium catalysts modified with chitosan (CS) and supported on MgO, SiO 2 , TiO 2 , and Al 2 O 3 were prepared by a precipitation method and evaluated in the low-temperature hydrogenation of 2-propen-1-ol. Chitosan was first deposited…
Zhou, Zhang, Wang et al. · 2026 · Molecules (Basel, Switzerland)
Recent studies indicate that ferroptosis shows unique advantages in oncotherapy, particularly in reversing multidrug resistance (MDR). Despite current therapeutic advancements, the treatment of high-incidence malignancies with dismal…
Baranowska, Kiss, Szeleszczuk · 2026 · Pharmaceutics
Dipeptidyl peptidase-4 (DPP-4) is an established therapeutic target in the treatment of type 2 diabetes mellitus (T2DM), primarily due to its role in regulating incretin activity and glucose homeostasis. Although clinically approved DPP-4…