A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19830 results in Negative / Null Result Report · page 249 of 661
Lüleci EH, Kedgley AE · 2026 · Human factors
ObjectiveThis study evaluated the effectiveness of age simulation gloves in replicating age-related declines in hand function.BackgroundCommercially available age simulation gloves are increasingly used. However, their ability to replicate…
Reimold AE, Wolfson JA, Lemmon B et al. · 2026 · JAMA network open
Importance Food systems account for approximately one-third of global greenhouse gas emissions (GHGE), and many foods with high GHGE pose risks to human health. Environmental impact (eg, climate) labels on restaurant menus may promote…
Başkan B, Başkan HK, Koç N · 2026 · PloS one
Objective This study aimed to evaluate and compare the performance of eight contemporary LLMs on the endodontics section of the DUS, assessing their accuracy in both theoretical knowledge and simulated clinical scenarios from historical…
Özçıbık Işık G, Turna A, Yurt S et al. · 2026 · Discover oncology
Objective Lung cancer is currently the leading cause of cancer-related death in men and the second most common cause in women worldwide. In the 9th edition of the TNM classification, N2 lymph node involvement has been divided into two…
Öğümsöğütlü E, Bozgeyik B, Huri G · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Purpose This study aimed to evaluate and compare the performance of the Chat Generative Pre-Trained Transformer (ChatGPT) and DeepSeek artificial intelligence (AI) models for patient information on shoulder instability. Methods Sixteen…
Ibrahim A, Abdelhady SA, Rageh F et al. · 2026 · BMC gastroenterology
OBJECTIVE: This study aimed to estimate the frequency of H. pylori infection in patients with liver disorders, and identify the relationship between vitamin D receptor gene variants and susceptibility to H. pylori infections and HCC in…
Vidal A, Teles AM, Cardoso M et al. · 2026 · Dentistry journal
Cone-beam computed tomography (CBCT) is widely utilized in endodontics for evaluating root canal shaping outcomes, offering critical three-dimensional imaging capabilities. This study aims to assess the differences in apical and root canal…
Mandler I, Krutik T, Biham O et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
BACKGROUND AND AIMS: Cardiac implantable electronic devices (CIEDs) are essential for the management of cardiac arrhythmias. Device infection is one of the most dismal complications of CIED implantation. The aim of this study is to assess…
Yang R, Li H, Duan M et al. · 2026 · Acta oto-laryngologica
Background Chronic suppurative otitis media (CSOM) is characterized by recurrent otorrhea and tympanic membrane perforation. The selection of surgical technique and suitable time for myringoplasty remain variable and unclear. Objectives…
Lomax JL, Mehta A, Vedantam A et al. · 2026 · Global spine journal
Study DesignScoping Literature Review.ObjectiveThe aim of this literature review is to examine the results of both skip laminectomy and oblique corpectomy in the setting of degenerative cervical myelopathy (DCM).MethodsA scoping review of…
Ding HB, Sun G, Yu GY et al. · 2026 · Frontiers in oncology
Background Postoperative quality of life (Post-QoL) is the key to measuring the effectiveness of sphincter-preserving operation such as Conformal sphincter preservation operation (CSPO) for ultralow rectal cancer. This study aimed to…
Najeb M, Samy A, Rizk A et al. · 2026 · Scientific reports
Tendon injuries pose a significant challenge in equine medicine due to the inherently limited regenerative capacity of tendon tissue and the high likelihood of reinjury. Recently, injectable platelet-rich fibrin (I-PRF) and exosomes…
Gong H, Yu H, Cheng FF et al. · 2026 · Photodiagnosis and photodynamic therapy
Objective Traditional Chinese Medicine (TCM) constitution represents a relatively stable individual characteristic, whereas physical fitness reflects overall physical condition. Both factors have been associated with adolescent health and…
Gardner DM, Williams B, Liu Z et al. · 2026 · microPublication biology
The BMP signaling pathway regulates body size and mesoderm fate specification in C. elegans . The secreted protein LON-1 both regulates and is regulated by BMP signaling. The mechanism through which LON-1 functions is unclear. In this…
Hamdan AL, Abou Raji Feghali P, Lababidi G et al. · 2026 · Journal of voice : official journal of the Voice Foundation
Objective To investigate the association between the morphology and the severity of Reinke's edema (RE) and disease regression following office-based blue laser therapy (OBLT) and steroid injection. Study design Retrospective Review…
Abdelgawad AH, Elhawy MA, Hussein AAHF et al. · 2026 · Urology research & practice
Objective Retrograde intrarenal surgery (RIRS) is the first-line treatment for kidney stones between 1 and 2 cm and can serve as an alternative to percutaneous nephrolithotomy for larger stones in high-risk patients, including those with…
Shen M, Li H, Liu H et al. · 2026 · Orthopaedic surgery
Background To explore the influence of the new stage and classification system based on the correlation between MRI and pathological features on the collapse, symptoms, and function of femoral head necrosis. Existing radiographic staging…
Bhochhibhoya A, Maskey B, Shrestha R et al. · 2025 · Preprint
Abstract Background. Artificial intelligence (AI) chatbots are considered a potential resource for dental education. However, there is still a lack of adequate knowledge regarding the trustworthiness, validity, and utility of the content…
Van Weydevelt E, Alrajhi Z, Vannier C et al. · 2026 · Journal of vascular surgery cases and innovative techniques
Objective Fenestrated and branched endovascular aortic repair (F/BEVAR) is increasingly used to treat complex abdominal aortic aneurysms and thoracoabdominal aortic aneurysms (TAAAs) because of their minimally invasive nature compared with…
Mkhize SF, Moodley J, Khaliq OP et al. · 2026 · South African family practice : official journal of the South African Academy of Family Practice/Primary Care
Background Pre-eclampsia (PE) is a major contributing factor to high rates of maternal and perinatal morbidity and mortality in South Africa. Early diagnosis is currently a challenge. The objective is to assess the diagnostic accuracy of…
Ali M, Higginbotham A, Sabri E et al. · 2026 · Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
Objectives Aspirin (ASA) is recommended for preeclampsia prophylaxis, but it is uncertain whether higher doses, such as the 150 mg/day used in the ASPRE trial, increase the risk of postpartum hemorrhage (PPH). In Canada, the available…
Ji Z, Sun H, Jiang Y et al. · 2026 · BMC cancer
OBJECTIVE: To compare accuracy and efficacy between Image Navigation System (INS, an optical tracking system for real-time needle guidance) combined with 3D printing template (3DPT) versus 3DPT alone in radioactive I-125 seed brachytherapy…
Abd-Elfadiel Hagag OY, Ahmed-Helmy El-Rayes M, El-Hawy AS et al. · 2026 · Tropical animal health and production
This study evaluated the impact of incorporating varying levels of dried Azolla pinnata as a partial or full substitute for soybean meal protein on growth performance, productivity, and selected biochemical, immunological, hormonal, and…
Meng D, Fan C, Dai Y et al. · 2026 · Shanghai kou qiang yi xue = Shanghai journal of stomatology
Purpose To observe the effect of different endpoints in chemical-mechanical caries removal for deep caries on the labial-buccal surface, and to provide reference for the selection of treatment methods and indications. Methods A total of 41…
Aslan S, Sozlu S, Bozkurt O et al. · 2026 · Journal of eating disorders
Aims Night eating syndrome (NES) is characterized by food consumption during bedtime or late night. This study aimed to evaluate the relationship between NES and resting metabolic rate (RMR), anthropometric measurements, and sleep quality.…
Xu S, Huang Z, Zou X et al. · 2026 · Journal of virus eradication
Background Elderly patients remain at high risk for adverse outcomes from COVID-19 despite the generally reduced pathogenicity of the Omicron variant. Corticosteroids are commonly used in hospitalized patients with COVID-19, particularly…
Scalia IG, Abdelfattah FE, Farina JM et al. · 2026 · Cardio-oncology (London, England)
BACKGROUND: Severe carcinoid heart disease (CaHD) may require bioprosthetic valve (BPV) replacement. Lutetium-177 (Lu-177) DOTATATE is increasingly utilized in patients with neuroendocrine tumors (NETs); however, its effect on BPVs remains…
Chantre-Justino M, Silvestre RT, Delmonico L et al. · 2026 · World journal of oncology
Background Bone sarcomas are rare and heterogeneous malignant neoplasms of mesenchymal origin, often associated with poor clinical outcomes. Being rare neoplasms, a comprehensive analysis of the molecular mechanisms involved in the tumor…
Akyuz C, Sunamak O, Selman A et al. · 2026 · Journal of clinical medicine
Background : Signet-ring cell colorectal cancer (SRCC) and colorectal cancer with a signet-ring cell component (SRC) are rare histological subtypes associated with poor prognosis. Although these entities are classified separately based on…
Fuchida H, Sawada D, Hirota T et al. · 2026 · Toxicology reports
Objective Lactobacillus gasseri CP2305 (L. gasseri CP2305) has been reported to exert intestinal regulatory, anti-stress, and sleep-improving effects in healthy adults. This study aimed to evaluate the safety of an excessive intake of L.…