Negative / Null Result ReportOpen accessMedicine
Zawar I, Zhu S, Quigg M et al. · 2026 · Brain communications
Epilepsy is a common comorbidity of Alzheimer's disease (AD) and related dementias (ADRD). Both epilepsy and ADRD affect the mesial temporal structures in volume and morphology. Nonetheless, mesial temporal shape and volume asymmetry…
View details →DOI: 10.1093/braincomms/fcag179 Negative / Null Result ReportOpen accessMedicine
Xu L, Wang X, Meng X et al. · 2026 · Oral health & preventive dentistry
Purpose To explore the relationship between dental caries and non-alcoholic fatty liver disease (NAFLD) and its advanced stage of liver fibrosis, and to confirm causality by employing a bidirectional two-sample Mendelian Randomization (MR)…
View details →DOI: 10.3290/j.ohpd.c_2714 Negative / Null Result ReportMedicine
Popovici I, Carvajal MJ, Higgins T et al. · 2026 · The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
Objectives While gender disparities in the US workforce have received substantial attention, income inequalities among subspecialty pharmacists remain understudied. This study aimed to develop a professional profile of pediatric…
View details →DOI: 10.5863/jppt-25-00095 Negative / Null Result ReportOpen accessMedicine
Stępień S, Morawiec ML, Smycz-Kubańska M et al. · 2026 · Frontiers in oncology
Ovarian cancer (OC) is a major clinical problem in gynaecological oncology, characterised by difficulties in early diagnosis, which contributes to the high mortality rate from OC. Therefore, the search for new biological markers continues,…
View details →DOI: 10.3389/fonc.2026.1757624 Negative / Null Result ReportOpen accessMedicine
Espinoza-Ríos J, Ruiz-Cortez R, Santiago B et al. · 2026 · BMC gastroenterology
Background Upper gastrointestinal bleeding (UGIB) remains one of the most common emergencies in gastroenterology, with mortality rates reaching 14% in some settings. Despite advances in management, mortality has remained relatively…
View details →DOI: 10.1186/s12876-026-04963-7 Negative / Null Result ReportOpen accessMedicine
Shinde N, Warad VG, Potkar S et al. · 2026 · Cureus
Introduction Type 2 diabetes mellitus (T2DM) is a growing global health concern. Emerging evidence suggests that vitamin D and calcium play an important role in glucose metabolism and insulin function. The present study aimed to compare…
View details →DOI: 10.7759/cureus.108040 Negative / Null Result ReportOpen accessMedicine
Spasić M, Todorović K, Živković N et al. · 2026 · Journal of functional biomaterials
Impacted mandibular third molars present a common challenge in oral surgery, often associated with postoperative complications such as delayed healing and periodontal defects; therefore, optimizing adjunctive therapies is clinically…
View details →DOI: 10.3390/jfb17060307 Negative / Null Result ReportOpen accessMedicine
Gül T, Seçme M · 2026 · Biomedicines
Background/Objectives : Neuroblastoma is the most frequent solid tumor outside the brain in children and is associated with unfavorable outcomes in high-risk patients. Tannic acid, a naturally occurring polyphenolic compound, has been…
View details →DOI: 10.3390/biomedicines14051117 Negative / Null Result ReportOpen accessMedicine
Thakur A, Singh BP, Parihar YS · 2026 · Cureus
Background Frozen shoulder (adhesive capsulitis) is a common cause of shoulder pain and disability in middle-aged adults, characterized by progressive pain and restriction of both active and passive range of motion. Despite multiple…
View details →DOI: 10.7759/cureus.105746 Negative / Null Result ReportMedicine
Chong JT, Yi H, Wang AE et al. · 2026 · Cardiovascular engineering and technology
Purpose The intracranial aneurysm (IA) model reconstruction is critical for pathophysiology diagnosis and computational simulations. This study aimed to quantify the impact of segmentation thresholds and software platforms on the…
View details →DOI: 10.1007/s13239-026-00841-1 Negative / Null Result ReportOpen accessMedicine
Wen Z, Ye Y, Chen H et al. · 2026 · Indian journal of orthopaedics
Objective To compare and verify the effectiveness of tendon-to-bone suture technique for the repair of external rotator injuries after hip arthroplasty. Methods This was a prospective, randomized, controlled study including 178 patients…
View details →DOI: 10.1007/s43465-026-01748-8 Negative / Null Result ReportOpen accessMedicine
Kondo K, Morita I, Sakuma S et al. · 2026 · PloS one
Objectives This study aimed to longitudinally examine nationwide changes in smoking behavior among the Japanese population in response to the COVID-19 pandemic. Design and setting A secondary analysis was conducted using cigarette sales…
View details →DOI: 10.1371/journal.pone.0350820 Negative / Null Result ReportMedicine
Borghgraef D, Sienaert P, Lambrichts S · 2026 · Canadian journal of psychiatry. Revue canadienne de psychiatrie
BackgroundPreventing relapse following a successful acute treatment of major depressive disorder (MDD) remains a clinical challenge. The presence of residual depressive symptoms seems to be a reliable predictor of relapse. However, few…
View details →DOI: 10.1177/07067437261448747 Negative / Null Result ReportOpen accessMedicine
Metin Yamac D, Erguven N, Ozenc E · 2026 · Anesthesiology research and practice
Aim The aim of this study is to compare the effect of intranasal and oral midazolam administered for premedication to children of preschool age on hemodynamic parameters, sedation, and separation from parents. Method A prospective,…
View details →DOI: 10.1155/anrp/4837750 Negative / Null Result ReportMedicine
Reina Abellán J, Bonato F, Ángel García D · 2026 · Military medicine
Background Elite acrobatic military parachutists are exposed to extreme repetitive axial loads and high gravitational forces, and low back pain (LBP) is common; however, the relationship between LBP and trunk neuromuscular function in this…
View details →DOI: 10.1093/milmed/usag301 Negative / Null Result ReportMedicine
Tasgaonkar A, Rathi N, Tasgaonkar M et al. · 2026 · European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry
Purpose Paediatric dental anxiety remains a significant challenge in clinical practice, often impacting co-operation and treatment outcomes. This randomised controlled trial compares the anxiety-reducing effects of AI-based self-modelling…
View details →DOI: 10.1007/s40368-026-01241-8 Negative / Null Result ReportOpen accessMedicine
Wong AJ, Donnell CC · 2026 · European journal of pediatrics
This study aims to synthesise and interpret evidence relating to fluoride-free toothpaste alternatives for caries prevention, examining how these products have been studied, the outcomes used to evaluate them, and how this evidence may…
View details →DOI: 10.1007/s00431-026-07176-y Negative / Null Result Report
Osei F · 2026 · Preprint
Abstract Drug repurposing and indication expansion remain important in pharmaceutical development, but the evidence supporting candidate drug--disease hypotheses is often fragmented across clinical trial registries, biomedical literature,…
View details →DOI: 10.21203/rs.3.rs-10046462/v1 Negative / Null Result ReportOpen accessMedicine
Zhao FY, Yue LP, Ho YS et al. · 2026 · Nature and science of sleep
Background and aims Insomnia during pregnancy is potentially associated with adverse outcomes, including gestational diabetes mellitus, pre-eclampsia, cesarean delivery, preterm birth, and depression. This study aimed to synthesize…
View details →DOI: 10.2147/nss.s607896 Negative / Null Result Report
Onaghise J, A DK · 2026 · Preprint
Abstract Background Rural working-age adults in West Africa face a compounding burden of rising non-communicable disease prevalence, specifically hypertension and diabetes, and severe structural barriers to accessing formal healthcare.…
View details →DOI: 10.21203/rs.3.rs-10096350/v1 Negative / Null Result ReportMedicine
Champion KA, AlDosari M · 2026 · Journal of dental education
Purpose Few evidence-based tools exist to support holistic review in dental school admissions. The Holistic Admissions Assessment Rubric (HAAR) was developed to score applicant data from the Associated American Dental Schools Application…
View details →DOI: 10.1002/jdd.70294 Negative / Null Result ReportMedicine
Zhou Y, Qin S, Ma Y · 2026 · Clinical and experimental hypertension (New York, N.Y. : 1993)
Background Essential hypertension (EH) remains a leading modifiable risk factor for cardiovascular morbidity and mortality worldwide. Electroacupuncture (EA), combining traditional acupuncture with pulsed electrical stimulation at specific…
View details →DOI: 10.1080/10641963.2026.2685125 Negative / Null Result ReportOpen accessMedicine
Sun Y, Yang X, Zhu Q et al. · 2026 · Drug design, development and therapy
Autoimmune thyroiditis (AIT) is a chronic immune-mediated thyroid disorder characterized by lymphocytic infiltration, follicular epithelial injury, autoantibody production, and variable progression to thyroid dysfunction. Because current…
View details →DOI: 10.2147/dddt.s614133 Negative / Null Result ReportMedicine
Aubret A, Triesch J · 2026 · Developmental science
There is strong and diverse evidence for mental rotation (MR) abilities in adults. However, current evidence for MR in children rests on just a few behavioral paradigms adapted from the adult literature. Here, we leverage recent…
View details →DOI: 10.1111/desc.70240 Negative / Null Result ReportMedicine
Yu J, Eyles JP, Moreti Cabral Silveira A et al. · 2026 · BMC health services research
Background Evidence based medicine is a critical cornerstone in contemporary medicine, yet uptake and adoption of evidence remain suboptimal. This is prominent in many fields of healthcare, including musculoskeletal health and surgery.…
View details →DOI: 10.1186/s12913-026-14843-1 Negative / Null Result Report
Parisien C, Ho-El Abidi N, Khalaf E et al. · 2026 · Preprint
Addiction is a chronic, relapsing disorder comprising three stages: binge, withdrawal, and preoccupation. Preclinical evidence suggests that the habenula, a small epithalamic region, is involved across these stages and may contribute to…
View details →DOI: 10.31234/osf.io/snyvc_v1 Negative / Null Result ReportMedicine
Sugita H, Sato MT, Yamaji N et al. · 2026 · The Cochrane database of systematic reviews
Rationale Non-communicable diseases (NCDs), such as hypertension, diabetes, and asthma, require continuous medication management. However, medication adherence remains suboptimal. Telepharmacy-defined as pharmacist-led care delivered…
View details →DOI: 10.1002/14651858.cd015136.pub2 Negative / Null Result ReportOpen accessMedicine
Champion S, Bilton R, Gordon S · 2026 · Australasian journal on ageing
Objectives This study evaluated the outcomes for individuals who completed an Innovator Training Program (ITP) funded by the Commonwealth Government of Australia and delivered by Aged Care Research & Industry Innovation Australia (ARIIA).…
View details →DOI: 10.1111/ajag.70162 Negative / Null Result ReportMedicine
Larvie DY, Güitrón Leal CE, Venkatramanan S et al. · 2026 · The Cochrane database of systematic reviews
Rationale Vitamin B 12 deficiency is an important public health problem in children, and has been associated with anaemia and impaired growth, cognition, and development. Vitamin B 12 deficiency may develop in children due to lower content…
View details →DOI: 10.1002/14651858.cd015264.pub2 Negative / Null Result ReportOpen accessMedicine
Shu W, Zhou Y, Sun E et al. · 2026 · Journal of medical Internet research
Background Embodied intelligence-artificial intelligence instantiated in physical or virtual bodies that can perceive, communicate, and interact with users and their environments-has been increasingly applied in health care. However, the…
View details →DOI: 10.2196/83871 