e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20227 results in Negative / Null Result Report · page 245 of 675

Negative / Null Result ReportMedicine

Host whole genome sequence data represent an untapped resource for characterising affiliated parasite diversity.

Nichols S, Estandía A, Young CM et al. · 2026 · International journal for parasitology

Parasites are ubiquitous and exert varied ecological and evolutionary pressures on their hosts. Yet, characterising parasite diversity and distributions can be challenging and costly. Leveraging existing data to identify parasites is thus…

View details →DOI: 10.1016/j.ijpara.2025.104768
Negative / Null Result ReportOpen accessMedicine

Impact of hepatitis B virus surface antigen mutations in the major hydrophilic region on antigen detectability.

He C, Gu X, Liu Y et al. · 2026 · Frontiers in cellular and infection microbiology

Objective This study aims to investigate the impact of mutations within the major hydrophilic region (MHR) of the hepatitis B virus (HBV) S gene on the expression, secretion, and antigenicity of hepatitis B surface antigen (HBsAg), and…

View details →DOI: 10.3389/fcimb.2026.1831437
Negative / Null Result ReportOpen accessMedicine

Detectability of Automated Tumor-feeder Detection Software Using Angio-computed Tomography in Transarterial Chemoembolization for Hepatocellular Carcinoma.

Ueda M, Mitani H, Nakaki Y et al. · 2025 · Interventional radiology (Higashimatsuyama-shi (Japan)

Purpose: To evaluate the performance of automated tumor-feeder detection software in transarterial chemoembolization for hepatocellular carcinoma using angio-computed tomography. Material and Methods: This was a retrospective study of 107…

View details →DOI: 10.22575/interventionalradiology.2025-0007
Negative / Null Result ReportMedicine

The severity and outcomes in acute pancreatitis do not differ between the elderly and non-elderly patients: Experience in a clinical tertiary center.

Ruiz-Rebollo ML, Muñoz-Moreno MF · 2025 · Medicina clinica

Background Acute pancreatitis can affect elderly people. Conflicting results have been published regarding the role of age in the course of this life-threatening disease. Aim To assess the clinical outcomes of acute pancreatitis in…

View details →DOI: 10.1016/j.medcli.2025.107112
Negative / Null Result ReportMedicine

Optical Genome Mapping in Myelodysplastic Syndromes: Clinical Value and Limitations Derived From a Cohort of 236 Patients.

Wei Q, Wang SA, Garcia-Manero G et al. · 2025 · Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Identification of cytogenetic abnormalities is critical for the classification and risk stratification of myelodysplastic syndromes (MDS). Optical genome mapping (OGM) is an emerging cytogenomic platform that enables high-resolution…

View details →DOI: 10.1016/j.modpat.2025.100862
Negative / Null Result ReportOpen accessMedicine

Comparative Diagnostic Accuracy of MRI and Ultrasound in Meniscal Tear Detection: Evaluating Reliability and Limitations Against Arthroscopic Outcomes.

Noorelahi Y · 2025 · Radiology research and practice

Objective Accurate meniscal tear diagnosis is essential for proper knee injury management. While MRI is the gold standard, ultrasound (US) offers a cost-effective alternative. However, its accuracy compared to arthroscopy remains…

View details →DOI: 10.1155/rrp/6270476
Negative / Null Result ReportOpen accessMedicine

Is Fel d1 Based Component Resolved Diagnosis Associated With Airway Inflammation in Cat Sensitized Children?

Kaya G, Yüksel H, Taneli F et al. · 2026 · Clinical and translational science

In cat sensitized children, decision to eliminate exposure to cats depends on the clinical outcome. In this study, we aimed to examine the relationship between molecular cat allergen sensitization and exhaled breath condensate (EBC) IL-4,…

View details →DOI: 10.1111/cts.70521
Negative / Null Result ReportMedicine

Detection of cross-reactivity of antibodies to the N proteins of feline morbillivirus and canine distemper virus in Japanese cat plasma samples.

Khin STMM, Jafar SM, Ju M et al. · 2025 · Journal of virological methods

Feline morbillivirus (FeMV) is a globally emerging virus that has been linked to chronic kidney disease (CKD) in infected cats. Immunological assays, such as enzyme-linked immunosorbent assay (ELISA), are important for studying the virus…

View details →DOI: 10.1016/j.jviromet.2025.115216
Negative / Null Result ReportOpen accessMedicine

Diagnostic performance of real-time characterization in artificial intelligence-assisted colonoscopy.

Lagström RMB, Bräuner KB, Frandsen MN et al. · 2026 · Endoscopy international open

Background and study aims Because most colorectal polyps are diminutive and carry minimal cancer risk, artificial intelligence (AI) might enable diagnostic strategies such as leave-in-situ and resect-and-discard, provided it meets…

View details →DOI: 10.1055/a-2860-7702
Negative / Null Result ReportMedicine

Revisiting proliferative glomerulonephritis with monoclonal immunoglobulin deposits through immunoglobulin repertoire sequencing.

Javaugue V, Pascal V, Nasr SH et al. · 2025 · Kidney international

Introduction Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is classified within the spectrum of monoclonal gammopathy of renal significance (MGRS). However, PGNMID features an unexpected low rate of…

View details →DOI: 10.1016/j.kint.2025.07.039
Negative / Null Result ReportMedicine

Review and practical excursus on the comparison between traditional statics methods and Classification And Regression Tree (CART) in real-life data: Low protein diet compared to Mediterranean diet in patients with chronic kidney disease.

Calabrese V, Metro D, Alibrandi A et al. · 2025 · Nefrologia

The Classification and Regression Tree (CART) is a supervised learning approach useful used to segment the space of and the predictors/features space into smaller homogeneous regions that are, represented in a decision tree. It computes…

View details →DOI: 10.1016/j.nefroe.2025.04.008
Negative / Null Result ReportOpen accessMedicine

Platelet antibody detection assays: a single-laboratory comparison of MAIPA, PIFT, and microsphere-based multiplex assays Pak-Lx.

Costa TH, Bonet-Bub C, Kutner JM · 2024 · Hematology, transfusion and cell therapy

Background and objectives The identification of platelet antibodies is essential for diagnosing and managing conditions such as fetal and neonatal alloimmune thrombocytopenic purpura, post-transfusion purpura, and immune platelet…

View details →DOI: 10.1016/j.htct.2024.06.004
Negative / Null Result ReportMedicine

Comparative efficacy of pre-moistened sponges and E-swabs for active surveillance of carbapenem-resistant Acinetobacter baumannii carriage.

Epchtien RE, Temkin E, Masarwa S et al. · 2025 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

We evaluated whether skin sampling with E-swabs is an effective alternative to pre-moistened sponges for detecting carbapenem-resistant Acinetobacter baumannii (CRAB) carriage. Skin samples were collected by sponges with enrichment and…

View details →DOI: 10.1007/s10096-025-05055-2
Negative / Null Result ReportOpen accessMedicine

Skeletal muscle protein turnover and mitochondrial responses to omega-3 fatty acid supplementation: an update.

Hayden JE, Deane CS · 2026 · Current opinion in clinical nutrition and metabolic care

Purpose of review To critically review recent findings related to the effects of omega-3 fatty acid supplementation on skeletal muscle, with a particular focus on skeletal muscle protein turnover and mitochondrial function. Recent findings…

View details →DOI: 10.1097/mco.0000000000001196
Negative / Null Result ReportMedicine

Assessing the performance of chest x-ray screening in detecting early-stage lung cancer in the general population.

Chei CL, Nakamura S, Watanabe K et al. · 2025 · International journal of cancer

Chest x-ray (CXR) is widely used for lung cancer screening in Japan. We evaluated the sensitivity and specificity of CXR in detecting early lung cancer and its histological types. We cross-referenced lung cancer municipality screening data…

View details →DOI: 10.1002/ijc.35316
Negative / Null Result ReportOpen accessMedicine

Video-Assisted Thoracoscopic Left Lower Lobectomy and Bronchial Foreign Body Removal for Treating a Rare Occult Bronchial Foreign Body in an Adult.

Shi Q, Bao J, Li J et al. · 2025 · Respirology case reports

Occult bronchial foreign bodies are extremely rare in adults. Affected patients typically lack a clear history of aspiration, exhibit no characteristic clinical signs and present with unremarkable chest imaging, often leading to…

View details →DOI: 10.1002/rcr2.70262
Negative / Null Result ReportOpen accessMedicine

Identifying a Critical Blind Spot: How Commercial AI (CAD) Systems Fail to Detect Faint Ground-Glass Opacities at -730 HU on Low-Dose CT.

Liang S, Wang J, Fu W et al. · 2026 · Diagnostics (Basel, Switzerland)

Objective: The integration of artificial intelligence (AI) into computer-aided detection (CAD) is a major innovation in lung cancer diagnosis. However, its reliability in detecting the earliest radiographic sign-faint ground-glass…

View details →DOI: 10.3390/diagnostics16071014
Negative / Null Result ReportOpen accessMedicine

Sentinel Lymph Node Detection Using SPECT and Gamma Probe in Low-Risk Endometrial Cancer: Efficacy and Factors Associated With Detection Failure.

Asanoma K, Yahata H, Kodama K et al. · 2025 · Asian journal of endoscopic surgery

Introduction This study examined factors that affected sentinel lymph node (SLN) identification of patients with endometrial cancer having a preoperative estimation of low recurrent risk. Methods This study included 97 patients with…

View details →DOI: 10.1111/ases.70015
Negative / Null Result ReportMedicine

[Application of optical genome mapping technology for the detection of chromosomal structural variations].

Zhang Z, He S, Li X et al. · 2024 · Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics

Objective To assess the value of optical genome mapping (OGM) for the detection of chromosomal structural abnormalities including ring chromosomes, balanced translocations, and insertional translocations. Methods Clinical data of four…

View details →DOI: 10.3760/cma.j.cn511374-20230107-00013
Negative / Null Result ReportOpen accessMedicine

Pipeline evaluation of a state-of-the-art AI algorithm for detection of focal cortical dysplasia: insights into potential failure sources.

Esmeraldo MA, Chambers S, Kravutske Y et al. · 2026 · Brain informatics

Purpose MELD Graph is a state-of-the-art artificial intelligence (AI) model for automated detection of focal cortical dysplasia (FCD), but its performance remains limited, highlighting the need to investigate which aspects of the pipeline…

View details →DOI: 10.1186/s40708-026-00299-w