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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19830 results in Negative / Null Result Report · page 244 of 661

Negative / Null Result ReportMedicine

No serological association between Porphyromonas gingivalis or Prevotella intermedia and early spondyloarthritis: analysis from the DESIR cohort.

Zekre F, Neel T, Paul M et al. · 2026 · Clinical and experimental medicine

Porphyromonas gingivalis and Prevotella intermedia are key oral pathogens implicated in periodontal disease and have been associated with rheumatoid arthritis and specific categories of juvenile idiopathic arthritis. Whether oral dysbiosis…

View details →DOI: 10.1007/s10238-026-02204-5
Negative / Null Result ReportOpen accessMedicine

Residential radon exposure and lung cancer histology and stage: a population-based ecological study in Central Germany.

Ernst P, Rachow T, Henn S et al. · 2026 · Journal of cancer research and clinical oncology

Purpose Residential radon exposure is recognised as one of the leading environmental risk factors for lung cancer and acts synergistically with tobacco smoking. Thuringia, Germany, exhibits high geogenic radon potential; however,…

View details →DOI: 10.1007/s00432-026-06524-7
Negative / Null Result ReportMedicine

The impact of drains on postoperative seroma and infection after mastectomy: A retrospective study in Danish women with breast cancer.

Palshof FK, Korsholm RHR, Duriaud HM et al. · 2026 · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Introduction Postoperative drains are commonly used after mastectomy to reduce seroma formation, but evidence of the benefit remains unclear. We evaluated the effect of postoperative drains on seroma formation and infection after…

View details →DOI: 10.1016/j.ejso.2026.111970
Negative / Null Result ReportMedicine

Hematopoietic progenitor cells (HPCs) mobilization following high-intensity interval exercise in cancer patients undergoing bone marrow transplantation: preliminary results from a randomized controlled trial.

Zarekar T, Ahmadizad S, Hajifathali A et al. · 2026 · Stem cell research & therapy

Background and objective Hematopoietic progenitor cells (HPCs) mobilization is essential for successful bone marrow transplantation but may be impaired in cancer patients due to prior treatments. High-intensity interval exercise (HIIE) has…

View details →DOI: 10.1186/s13287-026-05084-4
Negative / Null Result ReportMedicine

Amplicon sequencing reveals impact of imidacloprid residues on diversity profile of grape fructosphere microbiota.

Deore P, Upadhyay A, Thekkumpurath AS et al. · 2026 · World journal of microbiology & biotechnology

In grape, fructosphere microbiota play an important role in nutrient cycling, pathogen suppression, berry quality, and fermentation processes. Insecticide imidacloprid (IM) is used to manage several insect pests of grape. However, the…

View details →DOI: 10.1007/s11274-026-05095-6
Negative / Null Result ReportMedicine

Reliability and readability of five AI chatbots for concussion health advice across retrieval augmented and pretrained models.

Huang H, Zhang C, Hu H et al. · 2026 · Scientific reports

Generative AI is rapidly entering patient education workflows, yet its safety profile for concussion management remains undefined. Utilizing the CHART framework, this cross-sectional audit assessed five platforms, specifically isolating…

View details →DOI: 10.1038/s41598-026-51281-9
Negative / Null Result ReportMedicine

Clinical Outcome of EMG-Based Pelvic Floor Biofeedback in Patients With Constipation-Impact of Prior Anorectal Manometry/Balloon Expulsion Test for Patient Selection. A Retrospective Study.

Kochhar S, Channapragada T, Shenoy V et al. · 2026 · Neurogastroenterology and motility

Introduction Pelvic floor biofeedback therapy (BFT) is the mainstay treatment for dyssynergic defecation, a condition defined by the Rome criteria. This retrospective study compares outcomes between patients referred for EMG-based BFT…

View details →DOI: 10.1111/nmo.70373
Negative / Null Result ReportMedicine

Clinical Characteristics and Outcomes of Hemorrhagic Choroidal Detachments From 2003-2020: A Single Center Experience.

Tailor PD, Wang KY, Xu TT et al. · 2026 · Ophthalmic surgery, lasers & imaging retina

Background and objective This study aimed to characterize clinical characteristics and visual outcomes of patients with hemorrhagic choroidal detachments. Patients and methods Single-center retrospective case series of patients with…

View details →DOI: 10.3928/23258160-20260413-02
Negative / Null Result ReportMedicine

Comparison of Urodynamic Outcomes of Surgery Using the Photoselective Vaporization 180 W XPS System and Transurethral Resection of the Prostate: A Propensity Score-Matched Analysis in Real-World Clinical Practice.

Saito Y, Kyoda Y, Nofuji S et al. · 2026 · International journal of urology : official journal of the Japanese Urological Association

Objectives No previous studies have directly compared pre- and postoperative pressure flow study (PFS) outcomes between transurethral resection of the prostate (TURP) and photoselective vaporization of the prostate using the GreenLight XPS…

View details →DOI: 10.1111/iju.70532
Negative / Null Result ReportMedicine

Ultrasound structure function for quantitative assessment of steatotic liver disease based on total severity score.

Wallig MA, Kabir MR, Han A et al. · 2026 · The Journal of the Acoustical Society of America

Quantitative ultrasound parameters offer effective tools to evaluate microstructural changes in liver tissue and noninvasively assess tissue health. We examined the relationship between steatotic liver disease severity, measured by the…

View details →DOI: 10.1121/10.0043904
Negative / Null Result ReportMedicine

Predictors of Missed Appointments in Digestive Health: A Comparative Analysis of Telehealth and In-Person Visits.

Zaver HB, Reszczynski O, Singh A et al. · 2026 · Clinical and translational gastroenterology

Introduction Telehealth access is integral to digestive health care. This study examined demographic, insurance, and social determinants of health associated with missed telehealth appointments, with secondary comparisons with missed…

View details →DOI: 10.14309/ctg.0000000000001032
Negative / Null Result ReportMedicine

Rose danio (Danio roseus): A native Mekong basin alternative to zebrafish for acute, developmental, and neurobehavioral toxicity testing.

Seetapan K, Nobsathian S, Bullangpoti V et al. · 2026 · Environmental toxicology and chemistry

The fish embryo toxicity test is widely used as an alternative to conventional acute fish toxicity assays, but its ecological relevance may be limited when the model species is nonnative to the region of interest. Here, we evaluated rose…

View details →DOI: 10.1093/etojnl/vgag077
Negative / Null Result ReportMedicine

Advancements in Breast Lipofilling: A 12-Year Retrospective Comparative Analysis of Patient Satisfaction and Complication Rates across Fat Preparation Methods.

Loucas R, Loucas M, Müller R et al. · 2026 · Plastic and reconstructive surgery

Background Breast lipofilling is a commonly utilized method in plastic surgery for breast reconstruction and augmentation. However, the procedure is often limited by the unpredictable survival of fat grafts, leading to dissatisfied…

View details →DOI: 10.1097/prs.0000000000013135
Negative / Null Result ReportMedicine

Balancing relief and reflux: A prospective comparative study on gastric myotomy length and post-operative outcomes in laparoscopic Heller's myotomy for achalasia.

Yadav S, Kiran SP, Gurjar SK et al. · 2026 · Journal of minimal access surgery

Introduction Laparoscopic Heller's myotomy (LHM) with a partial fundoplication is the standard surgical therapy for achalasia cardia. However, the ideal gastric extension of the myotomy remains controversial, as it may influence both…

View details →DOI: 10.4103/jmas.jmas_534_25
Negative / Null Result ReportMedicine

Association Between Epicardial Adipose Tissue Thickness and Early Arrhythmia Recurrence After Electrical Cardioversion for Atrial Fibrillation and Atrial Flutter in Patients With and Without Heart Failure-An Observational Study.

Kadum F, Benko K, Batičić L et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : Atrial fibrillation (AF) and atrial flutter are associated with significant morbidity. While electrical cardioversion (ECV) is a standard treatment for sinus rhythm restoration, early arrhythmia recurrence is…

View details →DOI: 10.3390/medicina62061130
Negative / Null Result ReportMedicine

Autonomous dental implant robotics for transcrestal maxillary sinus floor elevation: workflow development and clinical trueness evaluation.

Qian J, Zi-Zheng W, Teng X et al. · 2026 · BMC oral health

Purpose To evaluate the trueness and safety of an autonomous dental implant robotic system (ADIRS) for transcrestal maxillary sinus floor elevation (TSFE), to compare outcomes between flat and sloped sinus floor morphologies, and to…

View details →DOI: 10.1186/s12903-026-08381-9
Negative / Null Result ReportOpen accessMedicine

Spinal Versus General Anesthesia for Lumbar Discectomy: Patient-Centered Analysis of Satisfaction with Anesthesia Service.

Rimaitis M, Bilskienė D, Rimaitis K et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives: Spinal (SA) and general anesthesia (GA) are both available for lumbar disc hernia (LDH) surgery. Patient satisfaction with anesthesia service is under-investigated and may help identify areas requiring…

View details →DOI: 10.3390/medicina62030524
Negative / Null Result ReportMedicine

Short Versus Extended Duration of Triple Antithrombotic Therapy After Percutaneous Coronary Intervention in Patients Requiring Oral Anticoagulation: A Retrospective Single-Center Study.

Kurpad KP, Vorla M, Bin-Farooq T et al. · 2026 · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

Background Balancing ischemic and bleeding risks in patients undergoing percutaneous coronary intervention (PCI) who require anticoagulation remains a clinical challenge. While dual antithrombotic therapy (DAT) with a P2Y12 inhibitor and…

View details →DOI: 10.1002/ccd.70667
Negative / Null Result ReportMedicine

Pediatric Robotic Cochlear Implantation: Hearing Outcomes.

Marie A, Leclere JC, Fleming Y et al. · 2026 · Audiology & neuro-otology

Introduction Cochlear implantation is the standard of care for children with severe-to-profound sensorineural hearing loss, offering substantial improvements in speech intelligibility, tonal audiometry perception, language acquisition, and…

View details →DOI: 10.1159/000551887
Negative / Null Result ReportMedicine

Coronary artery calcium and multiparametric cardiovascular risk assessment in non-dialysis chronic kidney disease.

Đuran I, Komazec N, Ljubičić B et al. · 2026 · Biomolecules & biomedicine

Cardiovascular disease is a leading cause of mortality in chronic kidney disease (CKD), but whether impaired renal function independently increases coronary artery calcium (CAC) burden in patients with comparable cardiovascular referral…

View details →DOI: 10.17305/bb.2026.14105
Negative / Null Result ReportMedicine

Generativity in Physician Assistants: Insights Amid a Preceptor Shortage.

Chung K · 2026 · The journal of physician assistant education : the official journal of the Physician Assistant Education Association

Introduction Amid a preceptor shortage, this pilot study examined the relationship between generativity, a psychosocial construct reflecting concern for guiding the next generation, and demographic characteristics among physician…

View details →DOI: 10.1097/jpa.0000000000000751
Negative / Null Result ReportMedicine

Tigecycline Use in Pediatrics: A Comprehensive Analysis of Clinical, Laboratory, and Microbiological Factors.

Arga G, Öcal D, Özdemir H et al. · 2026 · Turkish archives of pediatrics

Objective This study aimed to evaluate the indications and clinical and microbiological outcomes of tigecycline use in pediatric patients and to analyze the factors associated with treatment success and mortality. Methods The patients…

View details →DOI: 10.65717/turkarchpediatr.2026.25440
Negative / Null Result ReportOpen accessMedicine

Effectiveness of dexmedetomidine versus fentanyl on postoperative pain and recovery after pediatric tonsillectomy: A retrospective cohort study.

Jallad M, AlAnazi B, Aloqbawi A et al. · 2026 · Saudi journal of anaesthesia

Background Pediatric tonsillectomy is commonly associated with significant postoperative pain. Opioids remain a mainstay for perioperative analgesia but carry risks of respiratory depression and prolonged recovery, especially in patients…

View details →DOI: 10.4103/sja.sja_788_25
Negative / Null Result ReportMedicine

Association Between Frailty and Short-Term Treatment-Related Adverse Events in Patients With Overactive Bladder.

Iwagami S, Yamamoto H, Miyai H et al. · 2026 · Lower urinary tract symptoms

Objectives To evaluate whether frailty at treatment initiation is associated with treatment-related adverse events in patients with newly diagnosed overactive bladder (OAB). Methods This retrospective, single-center cohort study included…

View details →DOI: 10.1111/luts.70060