A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20227 results in Negative / Null Result Report · page 244 of 675
Jaghoub Q, Nacar E, Özdoğan A et al. · 2026 · Odontology
This study evaluated the initial effect of dental loupe use on the 3D accuracy of laminate veneer preparations performed by prosthodontic specialty residents under standardized in vitro conditions. Twenty-six residents completed two…
Erim B, Aray Y, Binici Hİ et al. · 2026 · Preprint
Abstract Advanced glycation end products (AGEs) are bioactive compounds implicated in oxidative stress, inflammation, and the development of chronic diseases. Skin autofluorescence (SAF) is a validated, non-invasive technique used to…
Vlassenbroek R, Peeters D, Matthewman L et al. · 2026 · The Journal of small animal practice
Objectives To assess the incidence of associative immune-mediated haemolytic anaemia in dogs diagnosed with immune-mediated haemolytic anaemia and to evaluate whether performing diagnostic imaging, specifically thoracic radiographs and…
Wu L, Xu X, Liu X et al. · 2026 · The Journal of craniofacial surgery
In patients receiving segmental Le Fort I osteotomy as part of a clear aligner treatment regimen, this study aimed to compare the clinical effectiveness of clear thermoplastic retainers as a postoperative stabilization technique and…
Nienaber S, Krabichler K, Fahlbusch D et al. · 2026 · Journal of the American Heart Association
Background Outcomes >2 years after transcatheter aortic valve replacement (TAVR) for bicuspid aortic valves (BAV) are scarce, and differences between balloon-expandable transcatheter heart valves (THVs) and self-expandable (SE-THVs) are…
Yanagiuchi T, Tokuda T, Yoshioka N et al. · 2026 · Journal of vascular surgery
Objective To compare the 3-year outcomes of Supera interwoven nitinol stents (IWNS) and Eluvia fluoropolymer-based drug-eluting stents (DES) in patients with severely calcified femoropopliteal lesions. Methods This multicenter…
Katragadda KP, Palestine AG · 2026 · Ocular immunology and inflammation
Purpose Methicillin-resistant Staphylococcus aureus (MRSA) is associated with a worse systemic prognosis compared to methicillin-sensitive S. aureus (MSSA). Prior studies of MRSA and MSSA endophthalmitis group endogenous and exogenous…
Łupina K, Dziewierz A, Janczura J et al. · 2026 · Acta diabetologica
Aims To characterize switching among GLP-1 receptor agonists (GLP-1 RAs) in a large private-sector cohort in Poland and to quantify therapy- and patient-level associations with switching while accounting for switching opportunity and…
Adams JL, Tong A, Chen P et al. · 2026 · Journal of emergency nursing
Introduction Team triage incorporates collaborative evaluation by physicians and nurses during initial assessment, differing from conventional nurse-only triage models. Although previous studies have demonstrated improvements in wait times…
Olasińska-Wiśniewska A, Swora-Cwynar E, Urbanowicz T et al. · 2026 · Nutrients
Background Acute kidney injury (AKI) is a frequent and prognostically important complication of cardiac surgery, yet early risk stratification remains challenging. The purpose of this prospective exploratory study was to determine whether…
Singh R, Williams DL, Alexander J et al. · 2026 · The Journal of arthroplasty
Background Medial unicompartmental knee arthroplasty (UKA), lateral UKA, and patello-femoral arthroplasty (PFA) are established treatments for isolated compartmental knee osteoarthritis. Despite its growing popularity, the comparative…
Zekre F, Neel T, Paul M et al. · 2026 · Clinical and experimental medicine
Porphyromonas gingivalis and Prevotella intermedia are key oral pathogens implicated in periodontal disease and have been associated with rheumatoid arthritis and specific categories of juvenile idiopathic arthritis. Whether oral dysbiosis…
Merdan S, Sarmış A, Aydoğan O et al. · 2026 · Sexually transmitted infections
Background Hepatitis C virus (HCV) coinfection is a significant comorbidity and public health concern among people living with HIV (PLWH). This study aims to estimate HCV seroprevalence among PLWH in Istanbul, Türkiye, and compare it with…
Che R, Milton A, Simpson R et al. · 2026 · Urology
Objective To evaluate prostate-specific antigen (PSA) screening patterns among gay and bisexual men and identify factors associated with screening uptake in this population. Methods We conducted a cross-sectional analysis using 2023…
Ernst P, Rachow T, Henn S et al. · 2026 · Journal of cancer research and clinical oncology
Purpose Residential radon exposure is recognised as one of the leading environmental risk factors for lung cancer and acts synergistically with tobacco smoking. Thuringia, Germany, exhibits high geogenic radon potential; however,…
Palshof FK, Korsholm RHR, Duriaud HM et al. · 2026 · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Introduction Postoperative drains are commonly used after mastectomy to reduce seroma formation, but evidence of the benefit remains unclear. We evaluated the effect of postoperative drains on seroma formation and infection after…
Zarekar T, Ahmadizad S, Hajifathali A et al. · 2026 · Stem cell research & therapy
Background and objective Hematopoietic progenitor cells (HPCs) mobilization is essential for successful bone marrow transplantation but may be impaired in cancer patients due to prior treatments. High-intensity interval exercise (HIIE) has…
Deore P, Upadhyay A, Thekkumpurath AS et al. · 2026 · World journal of microbiology & biotechnology
In grape, fructosphere microbiota play an important role in nutrient cycling, pathogen suppression, berry quality, and fermentation processes. Insecticide imidacloprid (IM) is used to manage several insect pests of grape. However, the…
Huang H, Zhang C, Hu H et al. · 2026 · Scientific reports
Generative AI is rapidly entering patient education workflows, yet its safety profile for concussion management remains undefined. Utilizing the CHART framework, this cross-sectional audit assessed five platforms, specifically isolating…
Kochhar S, Channapragada T, Shenoy V et al. · 2026 · Neurogastroenterology and motility
Introduction Pelvic floor biofeedback therapy (BFT) is the mainstay treatment for dyssynergic defecation, a condition defined by the Rome criteria. This retrospective study compares outcomes between patients referred for EMG-based BFT…
Brittenham C, Vanneau T, Molholm S · 2026 · The European journal of neuroscience
Autonomic responses to sensory stimuli are altered in autism, yet little is known about how multisensory input modulates these responses. This study examined whether auditory stimuli affect the pupil light reflex (PLR), a…
Tailor PD, Wang KY, Xu TT et al. · 2026 · Ophthalmic surgery, lasers & imaging retina
Background and objective This study aimed to characterize clinical characteristics and visual outcomes of patients with hemorrhagic choroidal detachments. Patients and methods Single-center retrospective case series of patients with…
Saito Y, Kyoda Y, Nofuji S et al. · 2026 · International journal of urology : official journal of the Japanese Urological Association
Objectives No previous studies have directly compared pre- and postoperative pressure flow study (PFS) outcomes between transurethral resection of the prostate (TURP) and photoselective vaporization of the prostate using the GreenLight XPS…
Wallig MA, Kabir MR, Han A et al. · 2026 · The Journal of the Acoustical Society of America
Quantitative ultrasound parameters offer effective tools to evaluate microstructural changes in liver tissue and noninvasively assess tissue health. We examined the relationship between steatotic liver disease severity, measured by the…
Zaver HB, Reszczynski O, Singh A et al. · 2026 · Clinical and translational gastroenterology
Introduction Telehealth access is integral to digestive health care. This study examined demographic, insurance, and social determinants of health associated with missed telehealth appointments, with secondary comparisons with missed…
Seetapan K, Nobsathian S, Bullangpoti V et al. · 2026 · Environmental toxicology and chemistry
The fish embryo toxicity test is widely used as an alternative to conventional acute fish toxicity assays, but its ecological relevance may be limited when the model species is nonnative to the region of interest. Here, we evaluated rose…
Loucas R, Loucas M, Müller R et al. · 2026 · Plastic and reconstructive surgery
Background Breast lipofilling is a commonly utilized method in plastic surgery for breast reconstruction and augmentation. However, the procedure is often limited by the unpredictable survival of fat grafts, leading to dissatisfied…
HOWARD G, CRETU C · 2026 · Preprint
Abstract This study examined differences in professional practice, teaching motivations, and self-efficacy beliefs between outdoor teachers (OT) and classroom-based teachers (TT) in Israeli elementary schools, addressing limited…
Yadav S, Kiran SP, Gurjar SK et al. · 2026 · Journal of minimal access surgery
Introduction Laparoscopic Heller's myotomy (LHM) with a partial fundoplication is the standard surgical therapy for achalasia cardia. However, the ideal gastric extension of the myotomy remains controversial, as it may influence both…
Kadum F, Benko K, Batičić L et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Atrial fibrillation (AF) and atrial flutter are associated with significant morbidity. While electrical cardioversion (ECV) is a standard treatment for sinus rhythm restoration, early arrhythmia recurrence is…