Negative / Null Result ReportMedicine
Minkley M, Ravasia K, Nghiem T et al. · 2026 · Virchows Archiv : an international journal of pathology
Pulmonary large cell neuroendocrine carcinoma (LCNEC) is an aggressive and molecularly heterogenous cancer with poorly defined treatment strategies. We aimed to (i) assess whether RB1 immunohistochemistry alone can prognostically stratify…
View details →DOI: 10.1007/s00428-026-04440-2 Negative / Null Result ReportMedicine
Kakihara S, Busza AM, Duffy BV et al. · 2026 · American journal of ophthalmology
Objective To determine whether foveal avascular zone (FAZ) enlargement and geometric perfusion deficits in the deep capillary plexus (GPDd) are independently associated with retinal nonperfusion in different regions of ultrawidefield…
View details →DOI: 10.1016/j.ajo.2026.03.031 Negative / Null Result Report
Bansaghi S, Klein J · 2026 · Preprint
Background Cruise ships are relatively small, crowded spaces where many people travel in a new environment, making infection control especially important. Proper hand hygiene is the first line of defense against the spread of infection.…
View details →DOI: 10.12688/openreseurope.20172.3 Negative / Null Result ReportMedicine
Kuula L, Pesonen AK · 2026 · The Journal of adolescent health : official publication of the Society for Adolescent Medicine
Purpose Many adolescents develop very late circadian rhythms, indicating delayed sleep phase. Interventions are sparse, and the stability of any improvements is rarely reported. To evaluate how late sleep patterns can be improved, we…
View details →DOI: 10.1016/j.jadohealth.2025.12.247 Negative / Null Result ReportOpen accessMedicine
Silva LEV, Balcarcel D, Ko TS et al. · 2026 · Resuscitation
Aims Heart rate variability (HRV), a non-invasive measure of autonomic function, may offer prognostic value after pediatric cardiac arrest. We used machine learning models to determine whether HRV features within the first 24 h after…
View details →DOI: 10.1016/j.resuscitation.2026.110961 Negative / Null Result ReportMedicine
Miao Y, Zhang H, Wu J et al. · 2026 · Journal of clinical anesthesia
Background Clinical evidence on obturator nerve involvement after supra-inguinal fascia iliaca compartment block (SFICB) is limited. This study aimed to investigate whether a 40-mL SFICB reliably anesthetizes the obturator nerve and…
View details →DOI: 10.1016/j.jclinane.2026.112193 Negative / Null Result Report
Bori-Bru B, Salvador JP, Crehuet R · 2025 · Preprint
Generative models have advanced profusely in recent years, generating great impact in computational modelling and structural bioinformatics. A part of computational protein design focuses on antibody and nanobody engineering, targeting…
View details →DOI: 10.64898/2025.12.12.693880 Negative / Null Result ReportMedicine
Najjar-Debbiny R, Cohen R, Arbel A et al. · 2026 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
BACKGROUND: Mycobacterium simiae is an emerging cause of non-tuberculous mycobacterial pulmonary disease (NTM-PD) in the Middle East, yet treatment outcomes remain unclear. We aimed to evaluate clinical and microbiologic outcomes of M.…
View details →DOI: 10.1007/s10096-026-05468-7 Negative / Null Result ReportMedicine
Rhyu KH, Cho YJ, Chun YS et al. · 2026 · Clinical orthopaedics and related research
Background Cementing a new liner into a well-fixed acetabular cup with a deficient locking mechanism has been reported as a viable option, but concerns remain regarding complications such as dislocation and late loosening.…
View details →DOI: 10.1097/corr.0000000000003917 Negative / Null Result ReportMedicine
Sabharwal P, Kaur N, Kaur R et al. · 2026 · Journal of ultrasound
Objectives To determine the incremental diagnostic value of multiparametric quantitative ultrasound-integrating B-mode, Color Doppler, Strain, and Shear Wave Elastography (SWE)-in differentiating benign and malignant breast lesions, using…
View details →DOI: 10.1007/s40477-026-01116-0 Negative / Null Result ReportMedicine
Wang L, Pulgrossi RC, Anderson J et al. · 2026 · The journal of applied laboratory medicine
Background Acute graft-versus-host disease (aGVHD) is a common complication of allogenic hematopoietic cell transplantation (HCT). The aGVHD presymptomatic algorithm is comprised of 2 serum biomarkers, suppression of tumorigenicity 2 and…
View details →DOI: 10.1093/jalm/jfaf193 Negative / Null Result ReportMedicine
Delaye-Martínez MA, Aguilar-Rodea BP, Cardona-Ortiz AF et al. · 2026 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Purpose Nebulized colistin has shown promise in treating ventilator-associated pneumonia (VAP) due to carbapenem-resistant strains; evidence in burn patients is limited. This study evaluated the efficacy of nebulized colistin as an adjunct…
View details →DOI: 10.1007/s10096-026-05550-0 Negative / Null Result ReportMedicine
Rusa AM, Schmidlin PR, Sarkar P et al. · 2026 · Swiss dental journal
Large language models (LLMs) are increasingly used in clinical and educational settings. However, there is a paucity of data on LLMs' performance in specialized dental domains. This study assessed the performance of four LLMs, including…
View details →DOI: 10.61872/sdj-2025-04-04 Negative / Null Result ReportMedicine
Zou Q, Huang Q, Li J et al. · 2026 · International urology and nephrology
Background The optimal treatment strategy for androgen receptor pathway inhibitor (ARPI)-pretreated and chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC) remains unclear. Chemotherapy has limited efficacy as a…
View details →DOI: 10.1007/s11255-026-05064-w Negative / Null Result Report
Oscorbin IP, Smertina MA, Kunova MS et al. · 2025 · Preprint
The metal-binding periplasmic protein CusF has been proposed as a bifunctional tag enhancing solubility of recombinant proteins and enabling purification using Cu affinity chromatography. However, evidence for its performance remains…
View details →DOI: 10.20944/preprints202512.0908.v1 Negative / Null Result ReportMedicine
van Boven M, Bennis F, Onland W et al. · 2025 · IEEE journal of biomedical and health informatics
Machine learning models predicting neurodevelopmental outcome in preterm infants have great potential, but have often relied on inaccessible brain magnetic resonance imaging measurements. This study aimed to build models using readily…
View details →DOI: 10.1109/jbhi.2025.3559793 Negative / Null Result ReportMedicine
Hoyle JD Jr, Ekblad G, Dunwoody S et al. · 2026 · Prehospital emergency care
Objectives We sought to decrease pediatric prehospital dosing errors by implementing a bundled drug dosing safety system (DDSS). Multiple studies have demonstrated that pediatric prehospital drug-dosing errors occur at rates of > 30% for…
View details →DOI: 10.1080/10903127.2025.2609784 Negative / Null Result ReportMedicine
Ivanov AL, Reshetnyak EI, Sukacheva SA · 2026 · Stomatologiia
Objective To evaluate mandibular donor site healing after cortical bone graft harvesting in cleft patients, comparing outcomes of osteotomies performed with rotary burs and piezosurgery. Material and methods Fifty-three patients (64 bone…
View details →DOI: 10.17116/stomat202610501137 Negative / Null Result ReportMedicine
Marshall PW, Benatar JR, O'Halloran P et al. · 2026 · Heart, lung & circulation
Aim Suboptimal enrolment and engagement in cardiac rehabilitation remains a persistent issue worldwide. This study evaluated the impact of a nurse-specialist-delivered motivational interviewing (MI) and cognitive behavioural therapy (CBT)…
View details →DOI: 10.1016/j.hlc.2025.10.006 Negative / Null Result Report
Sponholtz MR, Ma D, Byrne PO et al. · 2026 · Preprint
ABSTRACT Herpes simplex virus type 2 (HSV-2) causes genital herpes through latent infection and periodic reactivation. Although antivirals alleviate symptoms, no prophylactic or therapeutic vaccines have been licensed. Glycoprotein B (gB)…
View details →DOI: 10.64898/2026.01.26.701809 Negative / Null Result ReportMedicine
Hagger V, Hendrieckx C, Cotterill A et al. · 2026 · Diabetic medicine : a journal of the British Diabetic Association
Aim To examine changes in psychological and clinical outcomes among adolescents and parents after structured type 1 diabetes education delivered in routine care. Methods Teens Empowered to Actively Manage Type 1 Diabetes (TEAM T1) is a…
View details →DOI: 10.1111/dme.70244 Negative / Null Result ReportMedicine
Nakatsuka M, Pelletier-Roy R, Paturi A et al. · 2026 · Spine
Study design Retrospective cohort study of patients undergoing single-level L5-S1 anterior or transforaminal lumbar interbody fusion between 2012 and 2024 at a single academic institution, with preoperative and one-year postoperative…
View details →DOI: 10.1097/brs.0000000000005643 Negative / Null Result ReportOpen accessMedicine
Perrier Q, Lablanche S, Moro C · 2026 · Lasers in medical science
Photobiomodulation (PBM) has been shown to protect pancreatic islets under inflammatory or metabolic stress, but its effects during hypoxia-reperfusion remain unclear. We evaluated PBM applied as preconditioning or during…
View details →DOI: 10.1007/s10103-026-04867-8 Negative / Null Result ReportMedicine
Li JL, Wu JH, Zhao X et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
BACKGROUND: The role of prophylactic cavotricuspid isthmus (CTI) ablation remains controversial in atrial fibrillation (AF) patients without atrial flutter (AFL). Given the strong association between AF, AFL, and age, this study aimed to…
View details →DOI: 10.1007/s10840-026-02305-x Negative / Null Result ReportOpen accessMedicine
Hertig D, Furian M, Müller J et al. · 2026 · ERJ open research
Background Little is known about the effects of portable supplemental oxygen therapy (SOT) to improve exercise performance in highlanders at risk for high-altitude pulmonary hypertension (HAPH). We aimed to investigate whether SOT improves…
View details →DOI: 10.1183/23120541.00724-2025 Negative / Null Result ReportMedicine
Martins BM, Vieira RAM, Bittencourt CS et al. · 2025 · Journal of dairy science
This study evaluated the effects of propionic acid inclusion (PAI; 0, 0.25, and 0.50% of fresh matter) and ensiling time (ENT; 30, 60, 90, 120, 150, and 180 d) on the chemical composition, fermentation profile, DM losses, and in situ…
View details →DOI: 10.3168/jds.2025-26841 Negative / Null Result ReportMedicine
Jeon SH, Song C, Jeon JH et al. · 2026 · Cancer research and treatment
Purpose The aim of this study was to identify subgroups of patients with pathologic N2 (pN2) non-small cell lung cancer (NSCLC) who may benefit from postoperative radiotherapy (PORT). Particular attention was given to evaluating whether…
View details →DOI: 10.4143/crt.2025.644 Negative / Null Result ReportMedicine
Moreau J, Neyraud C, Huguet H et al. · 2026 · European journal of cardiovascular nursing
Aims Despite significant medical advances in recent decades, cardiopulmonary fitness decreases faster in youth with congenital heart disease (CHD) than in healthy peers, resulting in impaired health-related quality of life (HRQoL) and…
View details →DOI: 10.1093/eurjcn/zvag115 Negative / Null Result Report
Juma OA, Ochieng ME, Magak NM et al. · 2026 · Preprint
Abstract Background ART has reduced HIV mortality, but dyslipidaemia and thyroid dysfunction are increasingly observed; effects in Kisumu County remain unclear. Methodology Serum lipids (TC, TG, HDL, LDL) and thyroid hormones (TSH, T4, T3)…
View details →DOI: 10.21203/rs.3.rs-9555257/v1 Negative / Null Result ReportMedicine
Steuber T, Graetz C, Springer C et al. · 2026 · International journal of dental hygiene
Objective This two-centre, double-blind, randomized, parallel-group study compared the efficacy and safety of a novel powered full-mouth cleaning device system (FMCD) with habitual toothbrushing (CG) in patients with generalized gingivitis…
View details →DOI: 10.1111/idh.70116 