A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20227 results in Negative / Null Result Report · page 242 of 675
Ishizawa H, Umemoto R, Yoshida N et al. · 2026 · Preprint
ABSTRACT Plants are colonized by characteristic microbiomes that help maintain plant health and function. However, the mechanisms that make these communities assemble in a consistent, repeatable manner remain poorly understood. Here, we…
Liu Y, Ju L, Shi L et al. · 2026 · Preprint
Abstract Previous studies have established that metabolic dysfunction-associated steatotic liver disease (MASLD) disrupts the intestinal barrier, allowing harmful microbial metabolites such as lipopolysaccharide (LPS) to translocate to the…
Fernandes S, Algarra M, Brandão ATSC et al. · 2026 · Nanoscale
While heteroatom doping is widely used to enhance the fluorescence of carbon dots, the actual mechanism underlying this claimed enhancement remains unclear. Herein, we report a systematic comparison between nitrogen-doped carbon dots…
Moreno-Ayala V, Medina-Sánchez JM, Zambrano AF et al. · 2026 · Ecotoxicology and environmental safety
The increasing production of plastics worldwide is a growing source of emerging contaminants, particularly bisphenol A (BPA), a major chemical additive in plastics that, as waste, ends up polluting aquatic ecosystems. This study…
Valmori A, Manzi C, von Hippel C · 2026 · Preprint
As workplaces become increasingly diverse in age and gender, understanding how discrimination affects employees' experiences and decisions to remain with their organisations is essential. This study examined how perceived ageism and sexism…
Gomez Isaza D, Rodgers E · 2026 · Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Daily temperature fluctuations are a ubiquitous feature of natural environments, yet our understanding of how ectotherms respond to thermal variability remains incomplete. Previous frameworks have predicted that exposure to variable…
Margiotta ER, Kennedy D, Hawkins LR et al. · 2026 · Global change biology
Plant functional traits moderate ecosystem responses to climate and exchanges of water and carbon between the land surface and the atmosphere. However, the extent to which diversity in functional traits influences global carbon and…
Zeng X, Zeng C, Zhou Y et al. · 2026 · Conservation biology : the journal of the Society for Conservation Biology
Multiuse marine protected areas (MMPAs) with varying levels of protection in different zones are increasingly being adopted to balance conservation and socioeconomic goals. However, the effect of these zone-based strategies on fish…
Utonga D, Tundui CS, Mkuna E · 2026 · Preprint
Abstract This study analysed the determinants of the levels of digital technology adoption (DTA) among SMEs in the fruit juice processing industry in Tanzania. Anchored in the Technology Acceptance Model (TAM) and the…
Moreira MM, Dias LPB, Guzman YC et al. · 2026 · Journal of evolutionary biology
Intracellular endosymbionts such as Wolbachia are generally thought to persist in host populations by inducing reproductive phenotypes that enhance maternal transmission, often at the expense of male hosts. Here, we examined the fitness…
Mukherjee K, Ren D, Moritz D et al. · 2026 · IEEE transactions on visualization and computer graphics
Multimodal vision-language models (VLMs) continue to achieve ever-improving scores on chart understanding benchmarks. Yet, we find that this progress does not fully capture the breadth of visual reasoning capabilities essential for…
Ramesh N, Klaiber P · 2026 · Acta psychologica
Academic self-efficacy is theorised to foster favourable academic outcomes. While academic self-efficacy is believed to have a reciprocal relationship with academic mastery experiences, longitudinal naturalistic investigations are…
Costan CA, Godsoe W, Bufford JL et al. · 2024 · Plant Ecol.
It has long been hypothesised that introduced species can evolve to become better competitors, which in turn will enable some of them to become invasive. The evolution of increased competitive ability hypothesis (EICA) gives a possible…
D'Andrea W, Freed S, DePierro J et al. · 2024 · Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)
The startle eyeblink reflex is thought to function as a means of orienting to salient stimuli, and, by proxy, sensitivity to threat cues. The absence or attenuation of this reflex may thus suggest disengagement from one's environment,…
Thalapalliyil K, Bobby Z, Dorairajan G et al. · 2025 · Saudi medical journal
Objectives To explore whether uniform supplementation causes iron overload among a cohort of South Indian non-anemic pregnant women with diabetes-in-pregnancy (DIP). Methods The study took place between May 2022 and May 2024 and consisted…
Öcal M · 2025 · Scientific reports
Cold-wave disasters cause substantial loss of life and property, yet their global patterns remain poorly understood in a warming climate. Using EM-DAT records (1951-2023), we quantified cold-wave disaster frequency, mortality, and damages…
Menpadi N, Chandra P, Dubey VK · 2025 · Journal of basic microbiology
We have earlier reported novel anti-leishmanial molecules, veratramine and hupehenine, targeting dephospho-coenzyme A kinase of the parasite. In our current investigation, we assessed the efficacy of these two steroidal alkaloids,…
Dias VF, Albuquerque-Lima S, Navarro DMAF et al. · 2025 · Plant biology (Stuttgart, Germany)
Perfume flowers provide chemicals as a resource for specialized pollinators, that is, male euglossine bees. This system has been recorded in at least 15 families of Neotropical Angiosperms, including species of the bromeliad genus…
Dobelmann J, Wilfert L · 2024 · Preprint
not-yet-known not-yet-known not-yet-known unknown Host density, genetic diversity and social structure are key factors influencing disease transmission in wildlife populations, but their interactions remain poorly understood in insects. We…
Bi S, Wang C, Liu H et al. · 2026 · Frontiers in psychology
This study uses secondary analysis of a health survey dataset to explore the impact of completion time on the reliability and validity of online questionnaires. A total of 1,758 chronic low back pain patients recruited online were included…
Yang Y, Xu L, Cao S et al. · 2026 · Industrial Crops & Products.
Accurate estimation of aboveground biomass (AGB) helps to monitor maize growth and yield prediction, and unmanned aerial vehicles (UAVs) have become one of the most significant technological tools in precision agriculture. However,…
Out H, Wang Z · 2025 · Preprint
Abstract Purpose As artificial intelligence (AI) models evolve into their next generations, their application in specialized medical fields requires rigorous validation. While large language models (LLMs) have shown promise in general…
dos Santos ALC, Assis R · 2025 · Preprint
ABSTRACT Gene deletion is traditionally viewed as a nonadaptive mechanism that eliminates functional redundancy, yet emerging evidence indicates that it disproportionately affects tissue-specific duplicates with unique functions. Here, we…
Durland M, Harsey SJ, Freyd JJ · 2026 · Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)
DARVO (Deny, Attack, Reverse Victim and Offender) is a common tactic used by perpetrators of interpersonal violence to deflect blame and responsibility. Individuals' exposure to perpetrator DARVO has previously been measured using the…
Abrevaya S, Rossi C, Rodgers R · 2025 · Preprint
Clothing size labels have been shown to influence women's mood, self-esteem, and body satisfaction. This study examined the effects of different sizing nomenclatures—specifically color-based versus category-based labeling—on women's body…
Kumar H, Nandini R · 2025 · Preprint
Burrowing is a complex behavior that has evolved repeatedly across animal lineages, yet its evolutionary origins and ecological correlates remain poorly understood in many mammalian groups. The order Lagomorpha , comprising pikas (…
Bayır BRH, Ulutaş C, Nazlı E et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Introduction Headache is one of the most common neurological complaints in children and adolescents. Headache especially migraine in childhood significantly impacts daily life activities, including academic performance, and social…
Manrique H, Castro-Llanos F, van Rompaey A et al. · 2025 · Applied Geography
Coca cultivation is expanding rapidly into the Amazon biome, raising concerns about its role in deforestation. While this relationship is well-studied in Colombia, Peru remains understudied in spatial modeling analyses. This study…
Pirritano M, Buescher J, Staubach P et al. · 2026 · Communications biology
Discrimination of self from non-self RNA is a critical requirement for any cell to respond to infections and to maintain cellular integrity. We report novel functions for two RNA-dependent RNA polymerases (RDRs) in Paramecium. In…
Zondo B, Smith R, Sibiya P et al. · 2025 · Preprint
Abstract This study investigates the factors influencing South Africa's wine exports to its top ten trading partners and the impact of climate change on these exports. Using a gravity model and a dataset spanning from 2002 to 2022, the…