Negative / Null Result ReportOpen accessMedicine
Rolver MG, Emanuelsson F, Nordestgaard BG et al. · 2025 · Cardiovascular diabetology
Background and objectives Elevated C-reactive protein (CRP) is a well-established marker of low-grade systemic inflammation often accompanying cardiometabolic diseases like type 2 diabetes. We sought to determine if plasma CRP…
View details →DOI: 10.1186/s12933-025-03028-5 Negative / Null Result ReportOpen accessMedicine
Chen D, Zhu T, Liu C et al. · 2025 · Medicine
Several observational studies have reported the change in gut microbiota (GM) composition in individuals with osteoporosis (OP); however, the genetic correlation and causal association between GM and OP remain undetermined. Large-scale…
View details →DOI: 10.1097/md.0000000000045031 Negative / Null Result ReportMedicine
Wagner H, Lam D, Nguyen AL · 2025 · Contact lens & anterior eye : the journal of the British Contact Lens Association
Purpose Appropriate framing of health information influences the adoption of health behaviors. This study explored whether (1) gain- or loss-framed health promotion messages, emphasizing positive or negative consequences, respectively,…
View details →DOI: 10.1016/j.clae.2025.102387 Negative / Null Result ReportMedicine
Sirirungreung A, Lee PC, Hu YH et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background The safety of using acetaminophen (paracetamol) during pregnancy has been questioned because of concerns about its potential negative impact on fetal development and the risk of adverse pediatric outcomes. We aimed to…
View details →DOI: 10.1158/1055-9965.epi-25-1034 Negative / Null Result Report
Bin R, Yi L, Xing-ping L · 2024 · Preprint
The sustainability of social security is increasingly important to countries worldwide, yet the impact of regulation on social security remains controversial. Most scholars and policymakers focus primarily on the influence of social…
View details →DOI: 10.20944/preprints202410.0918.v1 Negative / Null Result ReportMedicine
Prince Czarnecki JM, Shockley JM, Wasson L et al. · 2024 · Precision Agriculture
Cloudy skies reduce image quality obtained from unmanned aerial vehicles (UAV) due to variable lighting conditions imposed on the surface. This study provides a novel approach for identifying temporal windows of opportunity that show…
View details →DOI: 10.1007/s11119-023-10055-3 Negative / Null Result ReportMedicine
Peltonen K, Tammilehto J, Flykt M et al. · 2025 · Cognition & emotion
Research suggests that adverse childhood experiences (ACEs) can have life-long consequences on emotional functioning. However, it is unclear how ACEs shape the dynamic features of everyday emotions. In the current preregistered study with…
View details →DOI: 10.1080/02699931.2024.2434153 Negative / Null Result ReportOpen accessMedicine
· 2024 · Journal of cellular and molecular medicine
Xin Li, Hao Xu, Jianfeng Yi, Chunlu Dong, Hui Zhang, Zhengfeng Wang, Long Miao, Wence Zhou. miR-365 secreted from M2 Macrophage-derived extracellular vesicles promotes pancreatic ductal adenocarcinoma progression through the BTG2/FAK/AKT…
View details →DOI: 10.1111/jcmm.18188 Negative / Null Result ReportMedicine
Power MC, Lynch KM, Fang V et al. · 2025 · Environmental research
Background As dementia has a decades-long preclinical phase, earlier air pollution exposures may be more etiologically relevant to dementia risk than more recent exposures. Methods We estimated exposures at Atherosclerosis Risk in…
View details →DOI: 10.1016/j.envres.2025.122850 Negative / Null Result ReportMedicine
Kömürcü HF, Sever N, Gökdereli NS et al. · 2025 · Neurological research
Background It has been suggested that smokers have higher recanalization rate, lower risk of cerebral hemorrhage and better prognosis than non-smokers (smoking paradox) after reperfusion therapy in patients with acute ischemic stroke (IS).…
View details →DOI: 10.1080/01616412.2024.2448628 Negative / Null Result ReportMedicine
Andersen Z, Kilgore S, Waite-Cusic J et al. · 2025 · Journal of Dairy Science
Hispanic-style cheeses (HSC), particularly fresh soft varieties, have been associated with numerous outbreaks of Listeria monocytogenes, highlighting the need to identify product characteristics or interventions that could mitigate L.…
Negative / Null Result Report
Xu C, Yang G, Liu Y · 2024 · Preprint
Abstract Background Obstructive Sleep apnea (OSA) is a prevalent sleep disorder characterized by repetitive interruptions of breathing during sleep, significantly impacting cardiovascular and metabolic health. Epigenetic aging, measured…
View details →DOI: 10.21203/rs.3.rs-5305378/v1 Negative / Null Result ReportOpen accessMedicine
Toyoshima M, Toyofuku R, Shimoda S et al. · 2026 · Neuropsychopharmacology reports
Adolescence is a sensitive developmental stage in which exposure to addictive substances can produce long-lasting changes in the neural circuits that regulate reward. Nicotine and ethanol are frequently co-used among adolescents, and…
View details →DOI: 10.1002/npr2.70132 Negative / Null Result ReportOpen accessMedicine
McVige J, Masset L, Mechtler L et al. · 2026 · Journal of child neurology
Mass psychogenic illness (MPI), also known as mass sociogenic illness, is a functional neurologic symptom disorder affecting multiple people simultaneously. This study presents a pediatric MPI outbreak involving abrupt-onset tics in LeRoy,…
View details →DOI: 10.1177/08830738251369759 Negative / Null Result ReportMedicine
Ferreira HRS, Hadden AC, Champagnon J et al. · 2025 · The Science of the total environment
Despite the vital importance of wetlands globally, these habitats have increasingly received anthropogenic materials, such as plastics, which can impact the wildlife these habitats support. Despite commonly found in the nests of Eurasian…
View details →DOI: 10.1016/j.scitotenv.2025.178588 Negative / Null Result ReportOpen accessMedicine
Ohlsen SM, Pirkle SB, Yang J et al. · 2026 · JSES reviews, reports, and techniques
Background Machine learning, a subset of artificial intelligence, enables large language models (LLMs) like ChatGPT and Gemini to analyze data, learn from context, and generate responses without explicit programming. While machine learning…
View details →DOI: 10.1016/j.xrrt.2026.100715 Negative / Null Result ReportMedicine
Qiu K, Hang Y, Lv P et al. · 2025 · Translational stroke research
To evaluate whether endovascular thrombectomy (EVT) combined with best medical management (BMM) is more effective than BMM alone in treating mild stroke patients (National Institutes of Health Stroke Scale score pri ) group and the primary…
View details →DOI: 10.1007/s12975-025-01337-1 Negative / Null Result Report
Radin D · 2024 · Preprint
The consciousness-collapse interpretation of quantum mechanics was explored by testing if human observation might act like a weak quantum measurement effect in an optical interferometer. Forty-seven participants selected via a worldwide…
View details →DOI: 10.31234/osf.io/t3jxk Negative / Null Result ReportMedicine
Wu Y, Xu Y, Bi Z et al. · 2025 · Journal of oral rehabilitation
Background Previous studies have linked sleep quality to temporomandibular joint disorders (TMD), suggesting a role for snoring in this association. However, the directionality of this relationship remains a subject of debate. This…
View details →DOI: 10.1111/joor.13916 Negative / Null Result ReportOpen accessMedicine
Yepes Gómez D, Moreno-Bedoya S, Lohle-Rueda S et al. · 2026 · Frontiers in nephrology
Background Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and carries high short-term mortality despite timely antimicrobials and organ support. Adsorptive hemofilters such as the oXiris ® membrane have…
View details →DOI: 10.3389/fneph.2026.1810007 Negative / Null Result Report
Horovitz O · 2024 · Preprint
Background: /Objectives: The growing interest in nutritional psychology has sparked exploration into how eating habits impact emotional, cognitive, and physical health. The Theory of Food (ToF) posits that childhood eating patterns shape…
View details →DOI: 10.20944/preprints202409.1895.v1 Negative / Null Result Report
Kiplagat E, Ramezani M, Malla S et al. · 2024 · Preprint
This study investigated the survival and growth of Salmonella in onion extracts and bulbs. Extracts of an array of onion varieties and germplasms were used to evaluate their ability to retard or inhibit Salmonella growth and the…
View details →DOI: 10.20944/preprints202411.1124.v1 Negative / Null Result ReportMedicine
Baumeister A, Schuurmans L, Schultz J et al. · 2025 · Behaviour research and therapy
Background and aim The efficacy of internet-based interventions (IBI) for various psychiatric disorders is widely established, but little is known about the mechanisms or possible influencing factors. One of the most prominent problems in…
View details →DOI: 10.1016/j.brat.2024.104673 Negative / Null Result ReportOpen accessMedicine
Zhan S, Zhang D, Ou Y · 2026 · Frontiers in psychology
Trauma-related distress in adult women often extends beyond posttraumatic stress disorder (PTSD) to include depressive symptoms and dissociation, yet the roles of mindfulness and self-compassion across these symptom domains remain…
View details →DOI: 10.3389/fpsyg.2026.1716193 Negative / Null Result ReportMedicine
Kurimoto M, Nawashiro T, Nagakura M et al. · 2025 · The Journal of craniofacial surgery
Craniosynostosis limits normal cranial growth, significantly affecting the growth and development of children. This increase in intracranial pressure results in significant cosmetic and functional losses. This study investigated the…
View details →DOI: 10.1097/scs.0000000000010799 Negative / Null Result ReportOpen accessMedicine
Mao J, Gan Y, Tan X et al. · 2025 · International journal of women's health
Objective High basophil count levels are associated with an increased risk of gestational diabetes mellitus (GDM). We used two-sample Mendelian randomisation (MR) to explore a potential causal relationship. It also aims to offer genetic…
View details →DOI: 10.2147/ijwh.s500632 Negative / Null Result ReportOpen accessMedicine
Killer HE, Pircher A, Stekhoven DJ · 2026 · Ophthalmology and therapy
Introduction The Collaborative Normal-Tension Glaucoma Study (CNTGS) is frequently cited as evidence that a 30% reduction in intraocular pressure (IOP) slows progression in normal-tension glaucoma (NTG). This study re-examines the…
View details →DOI: 10.1007/s40123-025-01300-1 Negative / Null Result Report
Schulz KM, Chavez MC, Forrester-Fronstin Z · 2024 · Preprint
Early pubertal onset during adolescence is consistently linked with increased risk of anxiety and depression in girls. Although estradiol tends to have anxiolytic effects in adulthood, whether sensitivity to estradiol’s anxiolytic actions…
View details →DOI: 10.1101/2024.09.02.610911 Negative / Null Result ReportMedicine
Yang Z, Su Q, Gao J et al. · 2026 · Acta psychologica
Scholars have emphasized the need for longitudinal research to investigate the reciprocal influence of personal belief in a just world (PBJW) and aggressiveness, yet such investigations remain limited. The current study aimed to examine…
View details →DOI: 10.1016/j.actpsy.2026.106597 Negative / Null Result Report
Poisson CL, Green IK, Stemmler GM et al. · 2024 · Preprint
To navigate dynamic environments, animals must rapidly integrate sensory information and respond appropriately to gather rewards and avoid threats. It is well established that dopamine (DA) neurons in the ventral tegmental area (VTA) and…
View details →DOI: 10.1101/2024.10.04.616744 