Negative / Null Result ReportOpen accessMedicine
Davis AE, Su Y, Dallas R et al. · 2026 · Emerging microbes & infections
Human astroviruses are a common cause of viral gastroenteritis and are often underdiagnosed. While infections are typically mild or asymptomatic in immunocompetent hosts, astrovirus can cause prolonged and severe disease in…
View details →DOI: 10.1080/22221751.2026.2616946 Negative / Null Result ReportOpen accessMedicine
Mittal A, Malhotra K, Panwar V et al. · 2026 · Urology research & practice
Objective: This retrospective cross-sectional analytical study evaluated the clinicopathological associations of programmed death ligand 1 (PD-L1) and human epidermal growth factor receptor 2 (HER2/neu) expression in 250 patients with…
View details →DOI: 10.5152/tud.2026.25061 Negative / Null Result Report
Bahta H, Kahsay A, Mewcha G · 2026 · Preprint
This study aims to assess beekeeper’s perceptions of honeybee colony behavior, climate related challenges and hive productivity in Tigray. The research design was used a mixed-approach method with multi-stage sampling techniques to select…
View details →DOI: 10.22541/authorea.15004610/v1 Negative / Null Result ReportOpen accessMedicine
Qiao X, Wang Y, Tian Z et al. · 2026 · Frontiers in psychiatry
Aim To explore the symptom distress and quality of life status of patients with Chronic Kidney Disease (CKD) Stage 5 undergoing hemodialysis in China, and their correlation. Methods The Dialysis Symptom Index (DSI) and the Kidney Disease…
View details →DOI: 10.3389/fpsyt.2026.1733502 Negative / Null Result ReportMedicine
Meade-Aguilar JA, Stovall R, Ramiro S et al. · 2026 · Joint bone spine
Objectives There are limited data on how NSAID use and dosage influence hypertension risk in axial spondyloarthritis (axSpA). We evaluated the association between NSAID use and incident hypertension in a longitudinal axSpA inception…
View details →DOI: 10.1016/j.jbspin.2026.106059 Negative / Null Result ReportOpen accessMedicine
Gonzalez DE, Dickerson BL, Hines K et al. · 2026 · Sports (Basel, Switzerland)
There are concerns that high-dose and/or long-term creatine monohydrate supplementation (CrM) leads to greater side effects (SEs) compared to placebo. This analysis investigated whether the dose or duration of CrM was associated with SEs.…
View details →DOI: 10.3390/sports14040137 Negative / Null Result ReportMedicine
Aljarallah S, Aldeligan SH, Almarshed A et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
PURPOSE.: Restless legs syndrome (RLS) is a common but under-recognised non-motor symptom in multiple sclerosis (MS), potentially linked to central nervous system lesion distribution. This study aimed to assess the anatomical distribution…
View details →DOI: 10.1007/s10072-026-08967-9 Negative / Null Result ReportMedicine
Yıldız P, Yurtseven A, Turan C et al. · 2026 · BMC pharmacology & toxicology
Methylphenidate is widely prescribed for attention-deficit/hyperactivity disorder, and its use has increased substantially in recent years. Although generally considered safe within therapeutic ranges, supratherapeutic ingestion may result…
View details →DOI: 10.1186/s40360-026-01177-1 Negative / Null Result ReportMedicine
Haksever M, Taşdemir D · 2026 · BMC pregnancy and childbirth
To evaluate the association between maternal hemoglobin and ferritin levels and fetal cortical maturation assessed by neurosonography between 30 and 34 weeks of gestation. This prospective observational study included 187 singleton…
View details →DOI: 10.1186/s12884-026-09529-9 Negative / Null Result ReportOpen accessMedicine
Kaushik A, Jaiswal A, Priya B et al. · 2025 · Journal of family medicine and primary care
Background Breast cancer is the most common cancer in women across the world. Immune cells can detect and destroy cancer cells. However, cancer cells acquire certain immune evasion mechanisms such as PD-1+ T-cells, to combat immune…
View details →DOI: 10.4103/jfmpc.jfmpc_320_25 Negative / Null Result ReportOpen accessMedicine
Zhou X · 2026 · Translational psychiatry
Low titers of blood circulating natural anti-NMDAR1 autoantibodies were reported in ~10% of the general human population. Their potential effects on NMDAR functions in the brain, however, remain unknown. We developed a new method to more…
View details →DOI: 10.1038/s41398-026-03878-x Negative / Null Result Report
Isikoglu BD, Senler FC · 2026 · Preprint
Abstract Purpose. Insomnia is a heterogeneous symptom cluster of multiple etiologies, frequently encountered in oncology patients, and chemotherapy has been implicated as a contributing factor. We aimed to evaluate the effects of…
View details →DOI: 10.21203/rs.3.rs-9973460/v1 Negative / Null Result Report
Coban S, Yavuz S, Dogan C et al. · 2026 · Preprint
Abstract Background Emergency department overcrowding is a persistent global public health issue, often driven by non-urgent visits. Health literacy is considered a key determinant of appropriate healthcare utilization. Objective This…
View details →DOI: 10.21203/rs.3.rs-9744500/v1 Negative / Null Result ReportOpen accessMedicine
Hiroshimaya T, Iwai K, Marutani M et al. · 2026 · Scientific reports
This study aimed to clarify the relationship between periodontitis and non-alcoholic fatty liver disease (NAFLD). A survey was conducted with 2,453 participants who visited the dental clinic at the Asahi University Hospital. Periodontitis…
View details →DOI: 10.1038/s41598-026-40128-y Negative / Null Result ReportOpen accessMedicine
Haddad A, Zabari Parnis E, Stein N et al. · 2026 · Vaccines
Background/Objective : The emergence of the COVID-19 pandemic has raised significant concerns regarding its impact on immune-mediated diseases, particularly with respect to disease induction and exacerbation. We aimed to investigate the…
View details →DOI: 10.3390/vaccines14040289 Negative / Null Result ReportMedicine
Wu Z, He S, Zhu F et al. · 2026 · Frontiers in endocrinology
Objective Copper overload has been implicated in impaired β -cell function and insulin resistance through oxidative stress and inflammatory pathways. As a major lipoprotein component involved in lipid oxidation, apolipoprotein B (apoB) may…
View details →DOI: 10.3389/fendo.2026.1764209 Negative / Null Result ReportOpen accessMedicine
Macian N, Dualé C, Delay M et al. · 2026 · European journal of pain (London, England)
Background Fibromyalgia is a syndrome characterised by widespread chronic pain, which is believed to be mediated by a state of central sensitisation (CS). Based on the hypothesis that CS itself could have genetic determinants, our aim was…
View details →DOI: 10.1002/ejp.70308 Negative / Null Result ReportOpen accessMedicine
Alharthy N, Alreefi M, Alsenani M et al. · 2026 · Pediatric health, medicine and therapeutics
Background Among children younger than 5 years, infectious conditions account for the majority of pediatric emergency department visits. Due to nonspecific presentation, early identification of Sepsis and serious bacterial infection is…
View details →DOI: 10.2147/phmt.s589691 Negative / Null Result Report
Uka-Kalu EC, Egesimba NC · 2026 · Preprint
Abstract Background: Drowning is a significant but often neglected public health issue, with low- and middle-income countries bearing a disproportionate burden. Young adults, particularly university students, represent a high-risk group…
View details →DOI: 10.21203/rs.3.rs-9501273/v1 Negative / Null Result Report
Buhari HM, Akpan SN, Ballah FM et al. · 2026 · Preprint
Abstract Foodborne illnesses remain a significant public health challenge in low and middle-income countries. Local food vendors operating in informal settings represent a critical point of intervention, yet their food hygiene knowledge…
View details →DOI: 10.21203/rs.3.rs-9811667/v1 Negative / Null Result ReportMedicine
Karabulut Ü, Yolaçan R, Ebik B et al. · 2026 · BMC gastroenterology
Background Duodenogastric reflux (DGR), defined as the retrograde flow of duodenal contents into the stomach, has an incompletely understood pathophysiology. This study aimed to evaluate the relationship between DGR and clinical,…
View details →DOI: 10.1186/s12876-026-05066-z Negative / Null Result ReportOpen accessMedicine
Maher AA, Maad AH, Al-Jaufy AY et al. · 2026 · Frontiers in medicine
Background Burn wound infections (BWIs) represent a major cause of morbidity and mortality among hospitalized burn patients. Pseudomonas aeruginosa is recognized for its ability to acquire multidrug resistance (MDR) and form biofilms that…
View details →DOI: 10.3389/fmed.2026.1762684 Negative / Null Result Report
Alayande AA, Williams JE, Olawuni DA et al. · 2026 · Preprint
Abstract Introduction: Abnormal anthropometric indices in children and adolescents, can potentially increase the risk of developing elevated blood pressure at a younger age. Children and adolescents with abnormal blood pressure at an early…
View details →DOI: 10.21203/rs.3.rs-8625118/v1 Negative / Null Result ReportOpen accessMedicine
Böckels L, Lisnic V, Alexa D et al. · 2026 · Journal of clinical medicine
Background/Objectives: Relapsing-remitting multiple sclerosis (RRMS) is frequently associated with anxiety and depressive symptoms, which significantly impact quality of life and clinical outcomes. The Hospital Anxiety and Depression Scale…
View details →DOI: 10.3390/jcm15114165 Negative / Null Result ReportMedicine
Shimada H, Lee S, Doi T et al. · 2026 · Gerontology
Introduction Walking speed is widely recognized as an informative indicator of physical capability in later life and is frequently used to evaluate mobility and functional health in older adults. Although the measurement of community…
View details →DOI: 10.1159/000550778 Negative / Null Result Report
Demirbaş SC, Kaba İ, Yilmaz M et al. · 2026 · Preprint
Abstract Objective Childhood obesity is a significant public health issue. Meteorin-like protein (Metrnl) is a newly identified adipomyokine that plays a role in energy metabolism and inflammatory processes. The aim of this study was to…
View details →DOI: 10.21203/rs.3.rs-9763274/v1 Negative / Null Result ReportOpen accessMedicine
Rosi Júnior J, Telles JPM, Santana LS et al. · 2026 · Arquivos de neuro-psiquiatria
Background Alpha 1-antitrypsin (A1AT) helps maintain vascular-wall integrity, but its role in the formation and rupture of intracranial aneurysms is unclear. Objective To compare A1AT levels between patients with ruptured and unruptured…
View details →DOI: 10.1055/s-0046-1820525 Negative / Null Result ReportMedicine
Kavrul Kayaalp G, Balcı MC, Kürkçü Güneş D et al. · 2026 · Cardiology in the young
Background Early identification of familial hypercholesterolaemia is critical to prevent long-term cardiovascular complications. This study assessed diagnostic features and age at diagnosis in children with familial hypercholesterolaemia…
View details →DOI: 10.1017/s104795112611302x Negative / Null Result ReportMedicine
Shinkawa K, Yoshida S, Nakao YM et al. · 2026 · Clinical and experimental nephrology
Introduction The clinical characteristics of patients with nephrotic syndrome undergoing in-hospital rehabilitation are not well-understood, and the effects of exercise on acute kidney injury (AKI) or venous thromboembolism (VTE) in this…
View details →DOI: 10.1007/s10157-026-02832-x Negative / Null Result Report
Conteville LV, Fernandes JPA, Frajacomo FT et al. · 2026 · Preprint
Abstract OBJECTIVES To examine the association between longitudinal trajectories of anthropometric nutritional status, physical activity, and overall survival among women with endometrial cancer. METHODS In a prospective cohort study, we…
View details →DOI: 10.21203/rs.3.rs-9438420/v1 