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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19823 results in Negative / Null Result Report · page 233 of 661

Negative / Null Result ReportMedicine

Effects of glucose ingestion on blood flow in the small intestine and exercising limbs during endurance exercise.

Endo MY, Kashima H, Miura A et al. · 2026 · Journal of applied physiology (Bethesda, Md. : 1985)

Performance during endurance exercise depends on the balance between the blood flow (BF) to active muscles and their energy use. We compared the acute cardiovascular regulation after the ingestion of a 300-mL drink containing 50 g glucose…

View details →DOI: 10.1152/japplphysiol.00954.2025
Negative / Null Result ReportMedicine

Clinical Characteristics and Management for Flares in Patients With Rheumatoid Arthritis Treated With Biologic and Targeted Synthetic Disease-Modifying Antirheumatic Drugs.

Kim YE, Ahn SM, Oh JS et al. · 2026 · International journal of rheumatic diseases

Objective To evaluate the frequency and management of flares in rheumatoid arthritis (RA) patients treated with biologic or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs). Methods Data were analyzed from the KOrean…

View details →DOI: 10.1111/1756-185x.70631
Negative / Null Result ReportOpen accessMedicine

[Corrigendum] Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria‑dependent apoptosis pathway.

Niu P, Sun Y, Wang S et al. · 2026 · Molecular medicine reports

Following the publication of the above article, an interested reader drew to the authors' attention that, concerning the TUNEL assay data shown in Fig. 5A on p. 6, the images shown for the H 2 O 2 and PU+H 2 O 2 groups were remarkably…

View details →DOI: 10.3892/mmr.2026.13849
Negative / Null Result ReportMedicine

A polymorphism and expression levels of SCD and their relationships to production traits in a Japanese farmed emu population.

Koshiishi Y, Moriya S, Ishida Y et al. · 2026 · PloS one

The emu is a novel poultry species producing meat, eggs, and fat. In particular, emu oil derived from the fat is considered the most important product of the emu owing to its anti-inflammatory and anti-melanin production. Meanwhile, there…

View details →DOI: 10.1371/journal.pone.0352695
Negative / Null Result ReportMedicine

Factors influencing time to speech processor upgrades.

Hung C, Spitzer ER, Waltzman SB · 2026 · Cochlear implants international

Objective Cochlear implant (CI) speech processors have undergone technological advancements. Therefore, patients upgrade speech processors when new features are available or when their previous device becomes broken and is no longer…

View details →DOI: 10.1080/14670100.2026.2635191
Negative / Null Result ReportMedicine

Non-alcoholic beverage provision reduces alcohol consumption and improves health-related outcomes, with no effect on presenteeism: a randomized controlled trial.

Dobashi S, Hotoge S, Kikuchi A et al. · 2026 · Scientific reports

Excessive alcohol consumption contributes to mortality and productivity losses, yet evidence for workplace-based substitution interventions remains limited. This randomized controlled trial examined whether providing non-alcoholic…

View details →DOI: 10.1038/s41598-026-58855-7
Negative / Null Result ReportMedicine

Pharmacokinetics of polyethylene glycol (PEG)-capped gold nanoparticles in rats: impact of free PEG pre-administration.

Darweesh RS, Alnuaimi TM, Zayed AL et al. · 2026 · Nanotechnology

Polyethylene glycol (PEG)-capped gold nanoparticles (PEG-AuNPs) are of great interest for targeted drug delivery and targeted delivery of chemotherapy due to their biocompatibility and ability to evade detection by the immune system.…

View details →DOI: 10.1088/1361-6528/ae4fc9
Negative / Null Result ReportMedicine

Early visual processing in adults with ADHD: evidence from contrast sensitivity, spatial integration, and external noise.

Ifrah-Tsruya H, Lev M, Polat U · 2026 · Vision research

Attention-Deficit/Hyperactivity Disorder (ADHD) is typically conceptualized as a disorder of executive control; however, accumulating evidence suggests that early sensory processing may also be atypical. The present study examined contrast…

View details →DOI: 10.1016/j.visres.2026.108867
Negative / Null Result ReportMedicine

Reliability of Noninvasive Blood Pressure Monitoring During Atrial Fibrillation Ablation Under General Anesthesia.

Schwartz J, Al-Sadawi M, Mattimore D et al. · 2026 · Journal of cardiothoracic and vascular anesthesia

Objectives To evaluate the accuracy and reliability of noninvasive blood pressure (NIBP) monitoring compared to invasive blood pressure (IBP) measurements during atrial fibrillation (AF) ablation under general anesthesia, and to determine…

View details →DOI: 10.1053/j.jvca.2026.03.003
Negative / Null Result ReportMedicine

Concomitant cholecystectomy did not significantly reduce the risk of subsequent biliary events and malignancy in treating gallstone ileus.

Su YS, Liu HY, Chen CY et al. · 2026 · Surgical endoscopy

Background This nationwide cohort study compared long-term subsequent benign biliary events and biliary tract malignancy in patients with gallstone ileus treated with or without concomitant cholecystectomy. Methods This retrospective…

View details →DOI: 10.1007/s00464-025-12536-0
Negative / Null Result ReportMedicine

Management of the Condyle in Posterior Mandibular Reconstruction: Major Clinical and Patient-Reported Outcomes.

Coleman-Belin JC, Zhang KK, Cohen Z et al. · 2026 · Journal of surgical oncology

Background and objectives Tumor involvement of the posterior mandible often requires resection of the mandibular condyle and associated soft tissue. This study explores clinical and patient-reported outcomes (PROs) associated with condyle…

View details →DOI: 10.1002/jso.70182
Negative / Null Result ReportMedicine

Investigating compensatory adjustments induced by rhythmic auditory stimulation for changes in temporal gait symmetry in lower-limb prosthetic users.

Gouda A, Arshad MZ, Andrysek J · 2026 · PloS one

Gait training is an important part of rehabilitation for prosthetic users, improving mobility and long-term health outcomes. This study investigated the effects of rhythmic auditory stimulation (RAS) on gait symmetry and overall movement…

View details →DOI: 10.1371/journal.pone.0351930
Negative / Null Result ReportMedicine

The effect of eggshell translucency on egg weight, embryonic development, hatching traits, chick quality, post-hatch growth, carcass, and organ traits in Ross 308 fast growing broiler strains at 7 days of age.

Abdallah N, Kursun K, Baylan M · 2026 · Tropical animal health and production

This study investigated the effect of eggshell translucency on egg weight, embryonic development, hatching traits, chick quality, post-hatch growth, carcass, and organ traits at 7 days of age in broiler chickens. A total of 300 hatching…

View details →DOI: 10.1007/s11250-026-04899-w
Negative / Null Result ReportOpen accessMedicine

[Corrigendum] Associations between Huwe1 and autophagy in rat cerebral neuron oxygen‑glucose deprivation and reperfusion injury.

He GQ, Chen Y, Liao HJ et al. · 2026 · Molecular medicine reports

Following the publication of the above article, the authors have contacted the Editor to explain that, regarding the immunofluorescence experiments shown in Fig. 3 on p. 5089, the data correctly shown in Fig. 3I (for the 'V‑ctrl+DMSO+R 24…

View details →DOI: 10.3892/mmr.2026.13833
Negative / Null Result Report

Patterns of Typical and Atypical Age-related Brainstem Volume losses

Mueller S, Mackin R · 2026 · Preprint

Background The brainstem and its different sub-systems control essential functions such as motor agility etc. that worsen with age. The purpose of this study was: 1. To assess the impact of age-related volume loss within three brainstem…

View details →DOI: 10.64898/2026.05.21.726989
Negative / Null Result ReportMedicine

Source of lateralization in reverse total shoulder arthroplasty matters: a comparison of glenoid and humeral lateralization on rotator cuff biomechanics.

Brusalis CM, Glenday J, Fu MC et al. · 2026 · Journal of shoulder and elbow surgery

Background Compared with the traditional Grammont design, modern reverse total shoulder arthroplasty (rTSA) implant designs often introduce lateralization of the glenoid and/or humeral components. This study aimed to evaluate the impact of…

View details →DOI: 10.1016/j.jse.2026.02.021
Negative / Null Result ReportMedicine

How mathematics anxiety relates to mathematical ability in AI agent-supported instruction: the moderating role of executive function.

Lin G, Tang B, Niu Y et al. · 2026 · BMC psychology

Mathematical ability is widely recognized as a core indicator of students' cognitive development and academic achievement. However, in classroom environments where artificial intelligence (AI)-supported instruction is increasingly…

View details →DOI: 10.1186/s40359-026-04994-5
Negative / Null Result ReportMedicine

Does the Combination of Calcium Hydroxide and Chlorhexidine Gel Affect Dentinal Tubule Penetration of Epoxy Resin and Tricalcium Silicate-Based Sealers?

Baran EK, Oncu A, Celikten B · 2026 · Australian endodontic journal : the journal of the Australian Society of Endodontology Inc

This study evaluated effect of calcium hydroxide (CH) medicaments prepared with distilled water, glycerin and chlorhexidine (CHX) gel on dentinal tubule penetration of epoxy resin- and tricalcium silicate-based sealers using confocal laser…

View details →DOI: 10.1111/aej.70093
Negative / Null Result Report

Analytical Discordance Between Point-of-Care Troponin Assays and a Central Laboratory High-Sensitivity Assay in a Sri Lankan Hospital Setting: Implications for Implementation

Fernando K, Fernando N, Jayasekara D et al. · 2026 · Preprint

Point-of-care testing (POCT) for cardiac troponin is increasingly used to support rapid clinical decision-making, particularly in resource-limited settings. However, while many central laboratories, including those in Sri Lanka, now use…

View details →DOI: 10.20944/preprints202605.1183.v1
Negative / Null Result ReportOpen accessMedicine

Preliminary examination of disgust learning as a potential OCD endophenotype.

Jessup SC, Zald DH, Olatunji BO · 2026 · Journal of affective disorders

Endophenotypes (intermediate phenotypes) are traits hypothesized to represent genetic risk for disorders such as OCD. However, it is unclear if disgust conditioning abnormalities may function as an OCD endophenotype. The present study…

View details →DOI: 10.1016/j.jad.2026.121619
Negative / Null Result ReportMedicine

Design and Preliminary Evaluation of a Hand-Held Surgical Robot for Enhanced Intuitive Control in Laparoscopy.

Kong K, Qiang Z, Yang Y et al. · 2026 · The international journal of medical robotics + computer assisted surgery : MRCAS

Background Surgical robots offer improved precision and stability for laparoscopy; nevertheless, their limited portability and high cost impede broader clinical applications. Methods This paper proposes a hand-held surgical robot with an…

View details →DOI: 10.1002/rcs.70176