Negative / Null Result ReportOpen accessMedicine
Xuetao Zhu, Yixiang Zhao, Kaiwen Liu et al. · 2024 · Scientific Reports
Abstract To compare the clinical efficacy of interlaminar endoscopic surgical system delta (iLESSYS-Delta) discectomy with that of classical fenestration discectomy for treating lumbar disc herniation. Patients who underwent iLESSYS-Delta or fenestration discectomy were enrolled in this study. Baseline information and clinical indicators were collected. The baseline data were matched using propensity score matching. Fifty-two patients were in each group. In the iLESSYS-Delta cohort, the volume of intraoperative bleeding was 18.17 ± 4.20 ml, the length of postoperative hospital stay was 4.16 ±
View details →DOI: 10.1038/s41598-024-70973-8 Negative / Null Result Report
Caldana M, Rusconi E · 2026 · Preprint
Olfaction is one of our most archaic senses but its central mechanisms are lesser known than those of other senses. In this work, we address a possible link between olfactory stimuli and mental spatial representations. Although olfactory…
View details →DOI: 10.31234/osf.io/nk3ty_v3 Negative / Null Result ReportOpen accessNursing
Nora Kasparaitytė, Juozas Raistenskis, Lina Budrienė et al. · 2025 · Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija
Background. Idiopathic scoliosis is among the most common spinal disorders diagnosed in 1–3% of children and adolescents. Treatment choice is related to disease severity, with a Cobb angle of 20–40°, a corrective brace or physiotherapy can stop its progression. However, insufficient research has shown whether combined treatment is better than monotherapy. Aim. To evaluate the effect of combining bracing and physiotherapy to reduce spinal deformity, improve quality of life and lung function, and compare the results with those of monotherapy. Determine the optimal duration of combined rehabilit
View details →DOI: 10.33607/rmske.v1i32.1603 Negative / Null Result ReportOpen accessPlant culture
Carlos I. Cortés-Martínez, Adriana Ines Rodríguez-Hernández, Ma del Rocío López-Cuellar et al. · 2023 · Plant Protection Science
Steinernema glaseri is a potential biocontrol agent against white grubs of the Phyllophaga spp. complex; however, its suitability for in vitro multiplication has been scarcely investigated. In this study, the effects of the surface culture of NJ-43 strain with its symbiotic bacteria Xenorhabdus poinarii on egg-yolk agar (P2), chicken-liver agar and nutrient meat-peptone (MP) agar on infective juvenile (IJ) productivity and their virulence against Galleria mellonella larvae were investigated. The bacteria on the surface of the agar were first incubated in darkness at 30 °C for 54-102 h, and the
View details →DOI: 10.17221/1/2023-pps Negative / Null Result ReportOpen accessMedicine
Fereshteh Baygi, Theis Bitz Trabjerg, Lars Henrik Jensen et al. · 2025 · JMIR Formative Research
BackgroundEnhancing care coordination and sharing information in cancer care improves patient experiences by promoting clarity and satisfaction. ObjectiveThis study aims to assess the impact of cross-sectoral video consultation on patient perceptions of care coordination and satisfaction with received information compared to usual care. MethodsThis study presents secondary outcomes on patient perceptions of care coordination and satisfaction with received information from a 7-month follow-up of the Partnership Project. In this randomized controlled trial, patients with cancer were allocated to
View details →DOI: 10.2196/76910 Negative / Null Result ReportOpen accessVeterinary medicine
Masato Katayama, Yukina Uemura · 2026 · Veterinary Sciences
Background: Feline chronic gingivostomatitis (FCGS) is refractory stomatitis in cats. The cure rate of tooth extraction selected as a primary surgical treatment is insufficient. Methods: 52 FCGS-suspected cats, including 22 tooth-extracted and 30 unextracted cats, were studied. Commercially available antiviral and antibacterial agents were orally administered as initial treatment, followed by the antiviral agent solely as maintenance therapy. We examined the influence of prior tooth extraction on the therapeutic efficacy of these two drugs by analyzing changes in some physical signs and clinic
View details →DOI: 10.3390/vetsci13040363 Negative / Null Result ReportOpen accessPublic aspects of medicine
Éva Bíró, Ferenc Vincze, Gabriella Mátyás et al. · 2021 · Frontiers in Public Health
Background: The public health relevance of health literacy is highlighted by the fact that its higher levels can improve health outcomes and reduce health inequities. In order to design effective interventions for improving health literacy, the relationship between health literacy and other factors such as sociodemographic variables, subjective health and social support must be understood.Objective: Our aim was to test a socioecological model of the determinants of health literacy with a special focus on the effect of residence. Our study investigated geographical differences regarding the lev
View details →DOI: 10.3389/fpubh.2021.724995 Negative / Null Result ReportOpen accessSurgery
J. Wong, K.F. Lee, P.S.F. Lee et al. · 2009 · Asian Journal of Surgery
Radiofrequency ablation (RFA) has been widely applied for the treatment of hepatocellular carcinoma and liver metastases. The reported mortality and morbidity rates are low. The aim of this study is to evaluate the safety and efficacy of RFA, and compare the results performed percutaneously versus surgically. Patients and Methods: From 2003 to 2006, 79 patients with hepatic malignancies (59 hepatocellular carcinoma, 20 liver metastases) with a total of 110 lesions underwent RFA in our centre. Post-ablation assessment by CT scan was performed in all patients at 1-, 3- and 6-month intervals. Pos
View details →DOI: 10.1016/s1015-9584(09)60003-8 Negative / Null Result ReportOpen accessSpecialties of internal medicine
Ahmad Safapour, Arash Alghasi, Farhad Abolnezhadian · 2021 · Journal of Preventive Epidemiology
Introduction: Immune thrombocytopenic purpura (ITP) is known as the most important cause of sudden drop in platelet count among children. The acute form of unexpected drop in platelet count in children calls for treatment with medications such as corticosteroids, intravenous immunoglobulin (IVIg), and Rho(D) immunoglobulin (anti-DIG). Most of the previous studies have accordingly compared short-term therapeutic outcomes of steroids with those of IVIg. In some cases, IVIg has led to better results. However, there are few studies on the long-term treatment effects of both medicine categories. Ob
View details →DOI: 10.34172/jpe.2021.03 Negative / Null Result ReportOpen accessAgriculture (General)
Monalisa Pereira Dutra, Giselle Pereira Cardoso, Eduardo Mendes Ramos et al. · 2012 · Ciência e Agrotecnologia
The use of liquid whey to replace water (at 0, 25, 50, 75 or 100%) in a restructured cooked ham formulation was studied and several technological and sensory quality properties were determined. The test results showed no statistically significant differences (P 0.05) less reddish (a* value reduction) and more grayish and yellowish (lesser C* and higher h values) with higher whey additions. A lower (P 0.05). These results suggest that up to 38% natural fresh liquid whey can be added to a restructured cooked ham formulation with similar results to products cured with a conventional formulation.
View details →DOI: 10.1590/s1413-70542012000100011 Negative / Null Result ReportOpen accessMedical physics. Medical radiology. Nuclear medicine
Yu Gao, Stephanie Yoon, Ting Martin Ma et al. · 2024 · Physics and Imaging in Radiation Oncology
Background and purpose: Magnetic Resonance Imaging (MRI)-guided Stereotactic body radiotherapy (SBRT) treatment to prostate bed after radical prostatectomy has garnered growing interests. The aim of this study is to evaluate intra-fractional anatomic and dose/volume metric variations for patients receiving this treatment. Materials and methods: Nineteen patients who received 30–34 Gy in 5 fractions on a 0.35T MR-Linac were included. Pre- and post-treatment MRIs were acquired for each fraction (total of 75 fractions). The Clinical Target Volume (CTV), bladder, rectum, and rectal wall were conto
View details →DOI: 10.1016/j.phro.2024.100573 Negative / Null Result ReportOpen accessScience
Ákos Bérczi, Fanni Éva Szablics, Anita Nelli Simon et al. · 2025 · Life
Digital subtraction angiography (DSA) remains an important reference modality for evaluating chronic limb-threatening ischemia (CLTI), with left transradial access (TRA) increasingly favored for its lower complication rates and patient comfort. Radiation safety for operators is paramount, yet the impact of patient positioning on scatter radiation during lower limb diagnostic catheter angiography (CA) is understudied. This single-center randomized controlled trial evaluated whether head-first (HF) vs. feet-first (FF) supine patient orientation affects operator radiation exposure during lower ex
View details →DOI: 10.3390/life15091433 Negative / Null Result ReportOpen accessNutrition. Foods and food supply
Maria Góis, Patrícia Batista, Magnólia Araújo et al. · 2023 · Beverages
Probiotic products have been the focus of research for several years due to the potential of their biological properties to impact mental health, mood, and cognitive functions. Kombucha is a probiotic drink that has been reported to be beneficial for mental health, particularly at the level of emotion regulation. This study aims to understand the perception of the Portuguese and Brazilian populations regarding the consumption of probiotics and Kombucha, as well as to understand these consumers’ perceptions related to the impact on emotion regulation (and the impact of this consumption on emoti
View details →DOI: 10.3390/beverages9030061 Negative / Null Result ReportOpen accessMedicine
Anthime Flaus, Armand Pattée, Guillaume Criton et al. · 2026 · Scientific Reports
Abstract [11C]Methionine ([11C]MET) PET provides high sensitivity to localize corticotroph pituitary neuroendocrine tumors (PitNETs) in de novo Cushing’s disease but remains inconclusive in up to 20% of cases. Current PET protocols rely on late acquisitions (20–40 min post-injection). Since other endocrine tumors present earlier peak tracer uptake, corticotroph PitNETs might also exhibit early differential amino acid uptake, compared to the normal pituitary gland. This exploratory study based on data derived from a previously registered prospective multicenter cohort study (ClinicalTrials.gov
View details →DOI: 10.1038/s41598-026-39219-7 Negative / Null Result ReportOpen accessMedicine
Amirsaeed Hosseini, Mohammad Yousofpour, Faranak Zaker et al. · 2026 · Journal of Mazandaran University of Medical Sciences
Background and purpose: Osteoarthritis is the most common cause of knee pain and has various treatment modalities. The Ferfion plant is a significant medicinal plant in traditional medicine used worldwide. This study aimed to investigate the effect of Ferfion herbal ointment on the clinical symptoms of patients with primary knee osteoarthritis. Materials and methods: This double-blind, randomized clinical trial was conducted on 50 patients with primary knee osteoarthritis at Baghban Clinic. Patients were divided into two groups of 25, receiving either Ferfion ointment or a placebo. The first g
Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Michael Christian Leitner, Michael Christian Leitner, Michael Christian Leitner et al. · 2023 · Frontiers in Neurology
IntroductionA significant number of Restitution Training (RT) paradigms claim to ameliorate visual field loss after stroke by re-activating neuronal connections in the residual visual cortex due to repeated bright light-stimulation at the border of the blind and intact fields. However, the effectiveness of RT has been considered controversial both in science and clinical practice for years. The main points of the controversy are (1) the reliability of perimetric results which may be affected by compensatory eye movements and (2) heterogeneous samples consisting of patients with visual field de
View details →DOI: 10.3389/fneur.2023.1114718 Negative / Null Result ReportOpen accessPharmaceutical industry
Gabriela Rister Figueiredo Irie, Marly Aparecida Spadotto Balarin, Mariangela Torreglosa Ruiz-Cintra et al. · 2016 · Revista de Ciências Farmacêuticas Básica e Aplicada
Endometriosis is a chronic gynecological disease that displays some features similar to malignancy, such as local invasion, aggressive spread to distant organs and angiogenesis. Polymorphisms of the ACE gene have been linked with some vascular disease. To determine the frequency of the ACE I/D polymorphism in Brazilian patients with endometriosis compared to controls. This case-control study included a total of 134 women (49 endometriosis patients and 85 controls) who had undergone a laparoscopy or laparotomy. Molecular analysis was performed by polymerase chain reaction (PCR). For the statist
Negative / Null Result ReportOpen accessMedicine
Meera Niranjan Khadilkar, Nitin Ankle, Sheetal Harakuni · 2017 · Bengal Journal of Otolaryngology and Head Neck Surgery
Introduction Controversy regarding treatment of tonsillitis based on throat culture report still persists. If surface culture is a determinant of bacteriology of the core, then rational therapy could be aimed at organisms cultured by surface swab. Materials and Methods A Cross-sectional study was conducted on 100 patients of chronic tonsillitis who underwent tonsillectomy. Tonsil surface and core swabs were studied for aerobic and anaerobic growth. Result Eighty seven percent patients had aerobic growth on tonsil surface and ninety percent in tonsil core. Staphylococcus aureus was the commones
Negative / Null Result ReportOpen accessMedicine
Jinmann Chon, Hee-Sang Kim, Jong Ha Lee et al. · 2018 · Annals of Rehabilitation Medicine
ObjectiveTo evaluate the association between balance function and asymmetry of knee extension strength in an elderly Korean population.MethodsThe strength of the knee extensors in each leg was measured in 306 community-dwelling elderly subjects (age, 76.70±4.85 years) and 25 young healthy subjects (age, 34.23±8.93 years). Based on the difference in strength of both legs, the elderly subjects were divided into symmetric (n=128) and asymmetric (n=178) strength groups using an asymmetry cutoff 20%. We determined the postural control ability of the subjects using InBody posturography, Berg Balance
View details →DOI: 10.5535/arm.2018.42.1.113 Negative / Null Result ReportOpen accessOtorhinolaryngology
Iqra Zakir, Ahmad Ahmad, Hamdan Pasha et al. · 2022 · Iranian Journal of Otorhinolaryngology
Introduction:Tympanoplasty is a common surgery for chronic otitis media and has conventionally been performed with a microscope for decades. The trend of endoscopic minimally invasive surgeries has been increasing worldwide for the last few decades. Few studies have discussed the outcomes of microscopic and endoscopic tympanoplasty. This study aims to compare results of tympanoplasty done with microscope vs endoscope in terms of graft take rate and improvement in conductive hearing loss.Materials and Methods:We did a retrospective review of 120 patients (54 male and 66 female) who underwent Ty
View details →DOI: 10.22038/ijorl.2022.61234.3104 Negative / Null Result ReportOpen accessBiotechnology
Katja Oberhofer, Patrick D. Wettenschwiler, Navrag Singh et al. · 2018 · Applied Bionics and Biomechanics
The introduction of hip belts to backpacks has caused a shift of loading from the spine to the hips with reported improvements in musculoskeletal comfort. Yet the effects of different hip belt tensions on gait biomechanics remain largely unknown. The goal of this study was to assess the influence of backpack weight and hip belt tension on gait biomechanics. Data from optical motion capture and ground reaction forces (GRF) during walking were acquired in nine healthy male subjects (age 28.0 ± 3.9 years). Six configurations of a commercial backpack were analyzed, that is, 15 kg, 20 kg, and 25 kg
View details →DOI: 10.1155/2018/4671956 Negative / Null Result Report
Fetene GD, Mengistu YA · 2026 · Preprint
Abstract This study investigates the effect of export diversification on growth. The study applied an extended Cobb-Douglas production function model using data sourced from the World Bank Indicator database, ranging from 1994 to 2024. The…
View details →DOI: 10.21203/rs.3.rs-8447625/v1 Negative / Null Result ReportOpen accessMedicine
Ullal Anand Nayak, Reena Sharma, Nilotpol Kashyap et al. · 2016 · Journal of Clinical and Diagnostic Research
Introduction: Chewing Side Preference (CSP) is said to occur when mastication is recognized exclusively/consistently or predominantly on the same side of the jaw. It can be assessed by using the direct method - visual observation and indirect methods by electric programs, such as cinematography, kinetography and computerized electromyography. Aim: The present study was aimed at evaluating the prevalence of CSP in deciduous, mixed and permanent dentitions and relating its association with dental caries. Materials and Methods: In a cross-sectional observational study, 240 school going children a
View details →DOI: 10.7860/jcdr/2016/20620.8422 Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Cecilia Higgs, James E. Hilbert, Libby Wood et al. · 2019 · Frontiers in Neurology
Introduction: Recent evidence demonstrates that women with myotonic dystrophy type 1 are at increased risk of reproductive organ tumors. However, studies of reproductive cancer risk factors in those patients are lacking.Methods: Using questionnaires, we collected and analyzed personal history information related to cancer risk factors from women enrolled in a UK and US registry for myotonic dystrophy (dystrophia myotonica; DM) patients.Results: The survey was completed by 242 DM type 1 (DM1) and 44 DM type 2 (DM2) women enrolled in the UK Registry (N = 124) and the US National Registry (N = 16
View details →DOI: 10.3389/fneur.2019.01071 Negative / Null Result ReportOpen accessDentistry
Ellen Christine Rodrigues Abreu, Vicente Colussi Ferreira , Karina Andrea Novaes Olivieri et al. · 2024 · Brazilian Dental Science
Objective: The aim of this study was to evaluate the marginal gap of frameworks produced using the CAD-CAM system, from zirconia and lithium disilicate blocks, adapted to a tooth preparation and a gypsum die. Material and Methods: For this study, a human first molar tooth was used as a master model with a full crown preparation. It was molded 20 times to obtain the gypsum die and randomly divided into 2 groups (n=10) for the fabrication of zirconia and lithium disilicate frameworks. The frameworks were made using pre-sintered zirconia blocks and lithium disilicate blocks, both CAD-CAM systems.
View details →DOI: 10.4322/bds.2024.e4154 Negative / Null Result ReportOpen accessSports medicine
Murilo Esteves Nogueira, Gabriela Oliveira Baptista, João Paulo Vello Marqueti et al. · 2018 · Revista Brasileira de Prescrição e Fisiologia do Exercício
O objetivo principal do treinamento resistido com pesos é promover a quebra da homeostase do organismo. Desde que dentro dos limites fisiológicos, o organismo gera o fenômeno da supercompensação, alcançando um novo nível de aptidão física. Diversas técnicas são usadas para alcançar o condicionamento físico, e a oclusão vascular (kaatsu training) surge como uma opção permeada por benefícios para sedentários e portadores de patologias, mas ainda com poucas evidências para a população treinada. O objetivo desse trabalho foi comparar a magnitude de dano muscular no exercício resistido com e sem oc
Negative / Null Result ReportOpen accessSocial sciences (General)
İbrahim Akkaş · 2026 · Sosyolojik Bağlam Dergisi
This study examines the multifaceted nature of identity attitudes among university students within the context of modernization and social transformation. Drawing on sociological approaches developed by Erik Erikson, Henri Tajfel, Pierre Bourdieu, Stuart Hall, and Anthony Giddens, identity is conceptualized as a dynamic and socially constructed process shaped by multiple forms of belonging, such as ethnicity, nation, religion, politics, and gender. The university environment is considered a critical social space where these dimensions of identity are negotiated and reproduced. The relationship
View details →DOI: 10.52108/2757-5942.7.1.6 Negative / Null Result ReportOpen accessMedicine
Hasan Demirkan, Mehmet Ozgur Kuzdan · 2022 · Haseki Tıp Bülteni
Aim:There is still a lack of sufficient evidence-based data on the standardized urodynamic patterns of urological disorders worldwide, particularly in the childhood age group. With this study, we sought to investigate the outcomes of urodynamic studies of common disorders frequently encountered in pediatric urology practice.Methods:Children who underwent urodynamic studies in a pediatric urology unit between March 2019 and September 2020 were included in the study. A retrospective review of data on demographic characteristics and cystometrogram findings of 266 children from the urodynamic labo
View details →DOI: 10.4274/haseki.galenos.2021.7771 Negative / Null Result ReportOpen accessMedicine
Mehmet Mahir Fersahoğlu, Ahmet Çakmak, Hüseyin Çiyiltepe et al. · 2022 · İstanbul Tıp Fakültesi Dergisi
Objective: To evaluate the effects of using different doses of ursodeoxycholic acid (UDCA) for six months in prevention of gallstones after Laparoscopic Sleeve Gastrectomy (LSG) on the formation of gallstones in the 6th and 12th months. Materials and Methods: The data of patients who underwent LSG for morbid obesity were analyzed. Three groups of 20 people were formed. These were the control group, Group I who were treated with UCDA 500 mg/day for six months after LSG, and Group II who were treated with UCDA 1000 mg/day for 6 months after LSG. Demographic characteristics, co-morbid diseases, c
View details →DOI: 10.26650/iuitfd.948141 Negative / Null Result ReportOpen accessMedicine
Videnović Nebojša, Mladenović Jovan, Pavlović Aleksandar et al. · 2019 · Srpski Arhiv za Celokupno Lekarstvo
Introduction/Objective. In this study, the effects of applied anesthetic techniques were investigated in a retrospective analysis of obese patients and those with normal body mass index undergoing in vitro fertilization, using bispectral index as an indicator of anesthetic depth. Methods. In total 116 patients with normal body mass index were allocated to group N. Another 116 patients with body mass index > 30 kg/m2 were allocated to group O. Anesthetic protocol comprised midazolam for premedication, diclofenac for pre-emptive analgesia, propofol for induction and maintenance, alfentanil for a
View details →DOI: 10.2298/sarh180227040v 