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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20227 results in Negative / Null Result Report · page 220 of 675

Negative / Null Result Report

USE OF MULTILOCAL MARKERS TO CONFIRM THE UNIQUENESS OF LEBEDYN CATTLE

N. В. Mokhnachova, O. M. Zhukorskyі · 2025 · Animal Breeding and Genetics

The aim of this study is to analyze the informativeness of ISSR markers in the study of intrapopulation genetic polymorphism of the Lebedyn local breed cattle population. Materials and methods of research. To confirm the uniqueness and…

View details →DOI: 10.31073/abg.69.08
Negative / Null Result Report

Modified string test to improve and confirm by molecular characterization for bacterial identification

Muhammad Dawood Mian, Saadullah Jan Khan, Rehana Rani et al. · 2026 · Access Microbiology

Rapid and reliable identification of bacteria is essential in clinical and environmental microbiology. Gram staining remains a widely used method for preliminary classification; however, it may require additional steps and can be difficult…

View details →DOI: 10.1099/acmi.0.000965.v3
Negative / Null Result Report

Disparities in receipt of complete diagnostic evaluation to confirm myelodysplastic syndromes.

Sudipto Mukherjee, Weichuan Dong, Abby Statler et al. · 2020 · Journal of Clinical Oncology

7555 Background: A complete diagnostic evaluation (CDE), including bone marrow (BM) biopsy, cytogenic testing, FISH panel, and/or flow cytometry, is widely accepted as a prerequisite for histopathologic confirmation of MDS. Earlier reports…

View details →DOI: 10.1200/jco.2020.38.15_suppl.7555
Negative / Null Result Report

Abstract P1-14-07: Randomized phase 3 study of anthracycline-containing regimens versus S-1 as first-line treatment for metastatic breast cancer (SELECT BC-CONFIRM)–A combined analysis of two randomized phase 3 studies (SELECT BC-CONFIRM and SELECT BC)–

Y Park, H Akabane, T Watanabe et al. · 2019 · Cancer Research

Abstract Background: Anthracycline-containing regimens and taxane have been standard as the first-line chemotherapy for metastatic breast cancer (MBC). We conducted SELECT BC (randomized phase 3 study of taxane versus S-1 as first-line…

View details →DOI: 10.1158/1538-7445.sabcs18-p1-14-07
Negative / Null Result Report

DETECTION FAILURE OF SMEAR MICROSCOPY TO CONFIRM PULMONARY TUBERCULOSIS

Yunusa EU, Bakare AT, Shagari GB et al. · 2018 · Caliphate Medical Journal

Background: The laboratories in poor resource settings commonly use smear microscopy for the diagnosis of pulmonary tuberculosis, because it is rapid, inexpensive and easy to perform. The commonly use Lowensten Jensen culture method for…

View details →DOI: 10.47837/cmj.19770126.20186141124
Negative / Null Result Report

Abstract 414: Ath28 Congenic Mice Confirm Atherosclerosis Modifying Gene on the Distal End of Chromosome 2

Juying Han, Jonathan D Smith · 2017 · Arteriosclerosis, Thrombosis, and Vascular Biology

Objective: Strain intercrosses between apoE-deficient mice on the AKR (athero-resistant) and DBA/2 (athero-sensitive) strains identified the Ath28 quantitative trait locus (QTL) on the distal end of chromosome 2 (chr 2). We bred congenic…

View details →DOI: 10.1161/atvb.37.suppl_1.414
Negative / Null Result Report

The relative vitamin A value of 9‐cis‐ and 13‐cis‐β‐carotene did not differ in vitamin A‐depleted Mongolian gerbils

Kara Allison Bresnahan, Christopher Davis, Sherry Tanumihardjo · 2011 · The FASEB Journal

The provitamin A biofortification of staple crops is a novel approach to ameliorating vitamin A status in countries where deficiency is prevalent. To assess the vitamin A impact of these crops, the unique bioefficacies of cis‐isomers,…

View details →DOI: 10.1096/fasebj.25.1_supplement.975.11
Negative / Null Result Report

The first- or second-line use of pemetrexed sequentially with EGFR-TKI did not differ in PFS for advanced NSCLC patients harboring EGFR-mutant tumors.

Zhen-Yu Ding, Yue-Yun Chen · 2017 · Journal of Clinical Oncology

e20531 Background: Both EGFR-TKI and pemetrexed doublet chemotherapy (P) are two effective therapies in advanced NSCLC patients with EGFR mutant tumors. But which one should be used in first-line remains controversial. Methods: This was a…

View details →DOI: 10.1200/jco.2017.35.15_suppl.e20531
Negative / Null Result Report

Nutritional Status of Water-soluble Vitamins Did not Differ According to Intake Levels of Wheat and Wheat Alternatives and Rice and Rice Alternatives as a Staple Food in Pregnant Japanese Women

Katsumi Shibata, Tsutomu Fukuwatari, Satoshi Sasaki · 2013 · Nutrition and Metabolic Insights

The objective of this study was to investigate whether the intake level of a staple food influences the nutritional status of water-soluble vitamins in pregnant Japanese women. Urinary excretion of water-soluble vitamins was used as a…

View details →DOI: 10.4137/nmi.s12980
Negative / Null Result Report

Cooled feline intestine and fresh intestine did not differ in enterotomy leak pressure testing or in gross wall thickness measurement

Annellie K. Miller, Penny J. Regier, Federico R. Vilaplana Grosso et al. · 2024 · Veterinary Surgery

Abstract Objective To report gross anatomical gastrointestinal measurements and compare enterotomy leak pressures between fresh and cooled feline cadavers. Study Design Ex vivo, randomized study. Animals Fresh feline cadavers ( n = 20).…

View details →DOI: 10.1111/vsu.14104
Negative / Null Result Report

Bax Expression of Throphoblast Cells did not Differ between Early and Late Onset Preeclampsia

Made Ariyana, Diah R. Hadiati, Irwan T. Rachman et al. · 2021 · Indonesian Journal of Obstetrics and Gynecology

Objective: To compare Bax protein expression in throphoblast cells of early and late onset PE.
 Methods: A cross sectional study involving 36 cases of early onset PE and 36 cases of late onset PE was conducted. Bax protein expression…

View details →DOI: 10.32771/inajog.v9i3.1430
Negative / Null Result Report

The effect of 0.5 mL mepivacaine administered as an abaxial sesamoid nerve block on lameness of horses with digital pain did not differ significantly from that of 2.5 mL of mepivacaine

Robert C. Cole, Fred J. DeGraves, Jessica Brown et al. · 2025 · American Journal of Veterinary Research

Abstract Objective To compare the effect of 2.5 mL 2% mepivacaine to the effect of 0.5 mL 2% mepivacaine administered over each palmar digital nerve, as an abaxial sesamoid nerve block (ASNB), to 6 horses lame because of naturally…

View details →DOI: 10.2460/ajvr.25.02.0042
Negative / Null Result Report

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

Alexandra Ryan, Boliang Wang, Fiona Dobson et al. · 2026 · Arthritis Care & Research

Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and…

View details →DOI: 10.1002/acr.80058
Negative / Null Result Report

Improvement in Long‐term Household Food Security among Indiana Households with Children did not Differ between Rural and Urban Counties after a Supplemental Nutrition Assistance Program‐Education Intervention

Rebecca L Rivera, Melissa K Maulding, Angela R Abbott et al. · 2016 · The FASEB Journal

Objective To determine the relationship of rural and urban county household status to long‐term food security among households with children in Indiana after a Supplemental Nutrition Assistance Program‐Education (SNAP‐Ed) intervention.…

View details →DOI: 10.1096/fasebj.30.1_supplement.674.26
Negative / Null Result Report

Clinical Outcomes of Follicular Thyroid Carcinoma Did Not Significantly Differ according to Tumor Size in an Iodine-Excessive Country

Da Eun Leem, Ji Hyun Yoo, Bo Ram Kim et al. · 2025 · Endocrinology and Metabolism

Background: Follicular thyroid carcinoma (FTC) measuring <2 cm is generally associated with good prognosis, while tumor size ≥4 cm is regarded as being associated with a poor prognosis. This study aimed to evaluate FTC prognosis by tumor…

View details →DOI: 10.3803/enm.2025.2324
Negative / Null Result ReportMedicine

Toxicity assessment of green energy by-product, lithium, using a novel suite of eight Australian aquatic-species tests from a Global Biodiversity Hotspot.

Nice, Storer, Fisher et al. · 2026 · Environmental toxicology and chemistry

Due to recent advances in green energy initiatives in response to climate change impacts, lithium exploration and production are rapidly increasing, with concomitant elevated lithium in discharges to waterways. However, lithium toxicity to…

View details →DOI: 10.1093/etojnl/vgag063
Negative / Null Result Report

Where Did All the Suspended Sediment Go?

Bruce S. Hart · 2026 · The Sedimentary Record

Studies of mud transportation and deposition in modern shelf settings indicate that fine-grained siliciclastic sediment is deposited from suspension in various ways. However, contemporary interpretations of ancient analogs (e.g., epeiric…

View details →DOI: 10.2110/001c.161170
Negative / Null Result Report

What Did They Say? What Did They Mean? Interpreting US Policies through Presidents’ Discourses at Historical Landmarks in Europe: A Study of Democracy Attributes

Ahmet Keser, Zeynep Elçin Kamalak · 2024 · Journal of Humanity and Society (insan &amp; toplum)

This study investigates how US Presidents addressed the attributes of democracy in their speeches at critical European sites and historical breakpoints. The aim is to analyze the content of the speeches and determine whether there is a…

View details →DOI: 10.12658/m0734
Negative / Null Result Report

Did Zhuangzi Criticize Mengzi?

Kim-chong Chong · 2024 · Dao

Abstract Mengzi 孟子 and Zhuangzi 莊子 lived around the same time in the mid–Warring States period of ancient China. The historical relation between them is unclear. There is no mention of each other in the texts named after them. But some…

View details →DOI: 10.1007/s11712-024-09975-2
Negative / Null Result Report

Did Jesus Teach Absolute Pacifism?

Carlo Filice · 2024 · The Acorn

Against the background of widespread use and justification of violence in Christian history, this paper reviews the text of the Christian Gospels to see if the words or deeds of Jesus or his followers indicate whether Jesus taught absolute…

View details →DOI: 10.5840/acorn202531835
Negative / Null Result Report

Did the Ways Part? New Models in Judean/Christian Relations

Michael Kok · 2017 · Axis Mundi

&#x0D; &#x0D; &#x0D; In this paper I reconsider the evidence for the traditional “Parting of the Ways” model, which posits an official separation of Judaism and Christianity between 70 and 135 CE. I argue that neither Rabbinic Judaism nor…

View details →DOI: 10.29173/axismundi78
Negative / Null Result Report

Did Early German Romanticism Impact Systems Theory?

Patrick Fortmann · 2015 · Journal of Literary Theory

Abstract The writings of Niklas Luhmann, the towering architect of modern systems theory, abound with references to the literature of early German Romanticism. Starting from this observation, the article investigates the relevance of…

View details →DOI: 10.1515/jlt-2015-0014