A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
750 results in Failed Experiment Report · page 21 of 25
Lambert M, Wambacq E, Devlamynck R et al. · 2026 · Plants (Basel, Switzerland)
Duckweed (Lemnaceae) is a promising alternative feed crop, particularly in regions with nutrient surpluses and protein deficits, as it grows efficiently on nutrient-rich agricultural wastewater and provides protein-rich biomass. However,…
Sedlacek Miskerikova M, Houfkova A, Benkova M et al. · 2026 · ACS medicinal chemistry letters
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) is a multifunctional mitochondrial enzyme and a potential drug target for the treatment of various pathologies, including Alzheimer's disease (AD). In this study, five new…
Bülbül N, Çiftçi R, Atik İ et al. · 2026 · Healthcare (Basel, Switzerland)
Background/Objectives: Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disorder associated with substantial long-term morbidity and mortality. Routinely collected anthropometric, biochemical, and hematological variables may…
Dowling EW, Sloman KN, McGarry KM et al. · 2026 · Journal of applied behavior analysis
Previous research on the relation between heart rate patterns and severe behavior has yielded mixed findings. Specifically, some studies have identified distinct heart rate patterns surrounding challenging behavior, whereas others have…
Leinbach D, Burcham DC, Kane B · 2026 · Preprint
Trees are routinely pruned to mitigate the risk of wind damage, but there are few studies examining changes in wind loads after pruning, especially for large conifers. In this study, ten Colorado spruces ( Picea pungens ) were monitored…
Eissa, Eleneen, Sedik · 2026 · BMC oral health
This study aimed to investigate whether the integration of functionalized carbon nanotubes (CNTs) with hydroxyapatite (HA) could create a bioactive nanocomposite capable of enhancing the early stages of osseointegration. Specifically, we…
Wu, Li, Fang et al. · 2026 · The International journal of neuroscience
This study aimed to evaluate the clinical value of upper limb rehabilitation robot-assisted training in stroke patients. A total of 101 stroke patients were assigned to either conventional rehabilitation plus robot-assisted upper limb…
Gujarathi, Belmont, Rodman et al. · 2026 · Annals of surgical oncology
The incidence of early onset (age < 50 years at diagnosis) appendiceal adenocarcinoma (EOAA) is rising alarmingly. Reported data on etiology, treatment, and outcomes is scarce. In this study, we report clinical outcomes for…
Yoshihara, Suwa, Kubota et al. · 2026 · NeuroImage. Clinical
Altered excitation-inhibition (E/I) balance has been implicated in the pathophysiology of major depressive disorder (MDD), but previous magnetic resonance spectroscopy (MRS) findings have been inconsistent, partly due to methodological…
Mohammad Kazem, Mohammad, Mohammad Hasan et al. · 2025 · Archives of Razi Institute
Mumps virus (MuV), a neurotropic member of paramyxoviridae, causes mumps disease. Since the 1960s, when the first live-attenuated vaccine against the MuV was developed, mumps outbreaks have dramatically decreased. A monkey-based…
Blue, Alvarez, Hines et al. · 2026 · Neurosurgery
Delayed facial nerve palsy (DFNP) is a recognized complication of vestibular schwannoma resection, with proposed mechanisms including viral reactivation, inflammation, and ischemia. Elevated herpes simplex virus and varicella zoster virus…
Araujo, Araujo, Silva et al. · 2026 · Journal of motor behavior
The study investigated the effects of ten 20-minute sessions of neurofunctional motor training combined with anodal transcranial direct current stimulation (tDCS) over the primary motor cortex or cerebellum on motor skills in autistic…
Idris, Burhan, Hajeer et al. · 2026 · The Journal of international medical research
ObjectiveTo investigate the effect of repeated submucosal administration of injectable platelet-rich fibrin in the buccal region of the lower incisors on orthodontically induced apical root resorption in patients with moderate…
Tam, Rezaee, Abdi et al. · 2026 · Acta parasitologica
Giardiasis is a globally common protozoan disease with significant public health impact, causing diarrhea, nausea, weight loss, bloating, and abdominal pain. Current treatments face limitations including drug resistance and adverse…
Chalasani, Vuppalanchi, Noureddin et al. · 2026 · Hepatology (Baltimore, Md.)
Belapectin reduced variceal development in a subgroup of patients with MASH cirrhosis. We report the efficacy and safety of belapectin in patients with MASH cirrhosis and portal hypertension without varices at baseline. NAVIGATE was a…
Chen, Liu, Xue et al. · 2026 · Molecular pain
The insular cortex (IC), a critical hub for nociception, emotion, and cognition processing, has emerged as a key role in the descending modulation of spinal cord excitability. Although previous studies have suggested that IC may influence…
Balcerac, Cuzzubbo, Bompaire et al. · 2026 · Revue neurologique
Since 2005, the standard treatment for newly diagnosed glioblastoma involves radiotherapy combined with concomitant and adjuvant temozolomide (TMZ), as per the Stupp protocol. A known long-term complication of radiotherapy is…
Md. Karimul Islam, Nishad Nasrin, Jannatul Naim et al. · 2023 · Humanities & Social Sciences Communications
Abstract Beggars have largely been leading miserable lives in the lower stratum of society since time immemorial. Government or private-led policies are rarely undertaken to improve the lives of this unfortunate societal segment. The local governments in divisional cities of Bangladesh have adopted a series of interventions aimed at improving the socioeconomic wellbeing of beggars and equipping them with alternative livelihood management options. We evaluated the effectiveness of this intervention (the rehabilitation of beggars) in the Khulna City Corporation (KCC) area, Bangladesh; we gathere
Dwayne D. Carney, Parth S. Vyas, J. Hicks et al. · 2022 · Foot & Ankle Orthopaedics
Category: Ankle; Trauma Introduction/Purpose: Ankle fractures are among the most common injuries that Orthopaedic Surgeons treat; yet, little guidance exists in postoperative protocols for ankle fractures concerning time of immobilization…
Mohamed Elsaggan, A. Shokry · 2019 · Egyptian Journal of Desert Research
he field work was carried out at the Experimental Farm of Desert Research Center at Siwa Oasis, Marsa Matrouh Governorate. During the two consecutive seasons of 2015/2016 and 2016/2017, the experiments were conducted to study the effect of…
Hannah Veinot, E. Folkerts, Ruhul et al. · 2019 · Alberta Academic Review
Cannabis is used for a variety of reasons such as relieving pain, relieving stress, and reducing nausea during chemotherapy. While cannabis originates from central and south Asia, the drug has become extremely popular in North America. In…
L. D. Singha, G. Saikia, B. Saikia et al. · 2022 · International Journal of Current Microbiology and Applied Sciences
The small ruminant husbandry sector in India is not an organized sector like poultry, however, now-a- days many young entrepreneurs are setting up goat units using scientific rearing practices, because small ruminants play an important…
Madison Van Doren, Casey Ford, Emily Dix · 2025 · arXiv.org
Multimodal large language models (MLLMs) are increasingly used in real world applications, yet their safety under adversarial conditions remains underexplored. This study evaluates the harmlessness of four leading MLLMs (GPT-4o, Claude…
Baek CH, Elhassan BT, Lim C et al. · 2026 · Archives of orthopaedic and trauma surgery
Introduction Although favorable clinical outcomes of scope-assisted lower trapezius tendon transfer (SALTT) have been reported in posterosuperior irreparable rotator cuff tears (PSIRCTs) patients, the limited restoring of static stability…
Cigdem Z, Durdu F, Celık MY · 2026 · BMC pediatrics
BACKGROUND: The study was carried out experimentally to determine the effect of prone and side-lying position on the comfort of preterm infants using positioning bed in preterm infants hospitalized in Neonatal Intensive Care Unit (NICU).…
Özdemir E, Bilen Ç, Karakuş E · 2026 · Biotechnology letters.
In this study, medlar polyphenol oxidase (PPO) was partially purified by (NH₄)₂SO₄ precipitation and dialysis, respectively. The aim of the study was to investigate the inhibition effects of amino acids, which are candidate PPO ligands, on…
Sangtani M, Mitra GV, Sangtani B et al. · 2026 · Bioinformation
Tooth extraction often results in trauma, leading to loss of alveolar bone and soft tissue. Therefore, it is of interest to compare the efficacy of physics forceps and conventional forceps in extracting non-carious and carious teeth. The…
Wang HK, Huang SH, Li CY et al. · 2026 · The journal of spinal cord medicine
Context/objective The optimal timing of surgical decompression for traumatic spinal cord injury (TSCI) remains uncertain. This study evaluated the association between ultra-early decompression and neurological outcomes, focusing on early…
Sofia Morgado, Filipa Valdeira, Niklas Sander et al. · 2026 · arXiv
Coronary angiography (CAG) reports contain clinically relevant physiological measurements, yet this information is typically in the form of unstructured natural language, limiting its use in research. We investigate the use of Large Language Models (LLMs) to automatically extract these values, along with their anatomical locations, from Portuguese CAG reports. To our knowledge, this study is the first addressing physiology indexes extraction from a large (1342 reports) corpus of CAG reports, and one of the few focusing on CAG or Portuguese clinical text. We explore local privacy-preserving gen
D. Kiderlen, P. Danielewicz · 1996 · arXiv
Generalization of Gaussian trial wave functions in quantum molecular dynamics models is introduced, which allows for long-range correlations characteristic for composite nuclear fragments. We demonstrate a significant improvement in the description of light fragments with correlations. Utilizing either type of Gaussian wave functions, with or without correlations, however, we find that we cannot describe fragment formation in a dynamic situation. Composite fragments are only produced in simulations if they are present as clusters in the substructure of original nuclei. The difficulty is traced