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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20227 results in Negative / Null Result Report · page 200 of 675

Negative / Null Result ReportMedicine

Dynapenic abdominal obesity and symptomatic knee osteoarthritis: results from a large cross-sectional study of middle-aged and older adults in China.

Chen, Jiang · 2026 · Annals of joint

Knee osteoarthritis (KOA) is a major cause of disability among middle-aged and older adults worldwide. Emerging evidence suggests that muscle strength may be more relevant than muscle mass for functional outcomes, yet the combined impact…

View details →DOI: 10.21037/aoj-2025-1-79
Negative / Null Result ReportMedicine

No link between piriform cortex subregion resection and seizure freedom in two cohorts with temporal lobe epilepsy.

Zahnert, Pfanzelt, Menzler et al. · 2026 · Journal of neurology

Postoperative seizure freedom in temporal lobe epilepsy (TLE) has been linked to the extent of piriform cortex resection. Earlier work used manual piriform cortex segmentations truncated at the limen insulae and overlapping the amygdala.…

View details →DOI: 10.1007/s00415-026-13850-w
Negative / Null Result ReportMedicine

Investigating the relationship between psychological stress and physical activity through individual-based geographic ecological momentary assessment.

Ge, Wang, Wu et al. · 2026 · Social science & medicine (1982)

Physical Activity (PA) is known to buffer stress, yet evidence remains limited when examining real-time stress responses alongside objective measures of activity and environmental exposures in daily life. To address the gap, this study…

View details →DOI: 10.1016/j.socscimed.2026.119411
Negative / Null Result ReportMedicine

Associations Between Mukbang Watching and Appetite, Nutrition, and Quality of Life in Pediatric Patients with Cancer: Intensive Longitudinal Study.

Xiao, Wang, Zhong et al. · 2026 · Journal of medical Internet research

Malnutrition is prevalent among children with cancer and is often exacerbated by diminished appetite. To combat this, hospitalized children are increasingly adopting mukbang, a popular online eating show genre. This study aimed to assess…

View details →DOI: 10.2196/80932
Negative / Null Result ReportMedicine

Horror Fandom, morbid curiosity, and psychological resilience amid war conflict and economic crisis among university students in Lebanon: a cross-sectional study.

Affan, Yammine, Karam et al. · 2026 · BMC psychology

Psychological resilience is crucial during prolonged instability, allowing individuals to adapt to change demands, manage intense stress, and maintain mental health. Engagement with horror media and morbid curiosity may be associated with…

View details →DOI: 10.1186/s40359-026-04792-z
Negative / Null Result ReportMedicine

Psychiatric hospitalization and rehospitalization among children and adolescents: evidence from 10-years electronic records in Beijing, China.

Zhu, Shi, Xia et al. · 2026 · BMC psychiatry

Enhancing inpatient services for children and adolescent mental illness is a primary goal of medical systems, yet knowledge of child and adolescent psychiatric hospitalization utilization is limited. This study aimed to characterize…

View details →DOI: 10.1186/s12888-026-08162-2
Negative / Null Result ReportMedicine

Views of EU citizens on economic growth and implications for climate policy.

Savin, King, van den Bergh et al. · 2026 · Nature communications

Although economic growth remains a central objective in policymaking and political discourse, its compatibility with environmental sustainability is increasingly contested. Yet it remains unclear whether this debate is reflected in public…

View details →DOI: 10.1038/s41467-026-73323-6
Negative / Null Result ReportMedicine

Predictors of psychosocial burden in parents of children with food allergy.

Kubala, Young, Callier et al. · 2026 · Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

The psychosocial burden of food allergy (FA) impacts the entire family, particularly the affected child and their parents. To evaluate psychosocial parental burden (PB) in families of children with FA, identify factors associated with PB,…

View details →DOI: 10.1016/j.anai.2026.05.010
Negative / Null Result ReportMedicine

Frailty and Severe White Matter Lesions Are Risk Factors for Surgical Treatment for Unruptured Cerebral Aneurysm in Older Adults.

Matano, Murai, Mizunari et al. · 2026 · Neurologia medico-chirurgica

It remains unclear whether frailty and white matter lesions are risk factors for surgical treatment of unruptured intracranial aneurysms in older adults. We conducted a prospective multicenter study of 397 patients aged ≥60 years…

View details →DOI: 10.2176/jns-nmc.2025-0241
Negative / Null Result ReportMedicine

Characteristics of COVID-19 cases and factors associated with disease severity in Lao People's Democratic Republic: a nationwide study.

Houatthongkham, Xangsayarath, Khamphaphongphane et al. · 2026 · BMC infectious diseases

This is the first nationwide analysis to describe the epidemiological and clinical characteristics of COVID-19 cases in Lao People's Democratic Republic (Lao PDR) and to identify factors associated with symptom-based disease severity…

View details →DOI: 10.1186/s12879-026-13543-9
Negative / Null Result ReportMedicine

First-trimester nonsteroidal anti-inflammatory drugs exposure and risk of major congenital malformations: A retrospective register-based cohort study.

Hasidim, Ben Shitrit, Idan et al. · 2026 · PLoS medicine

Pain and fever are common in early pregnancy, yet their management poses a major clinical dilemma. Although not confirmed, recent studies have raised safety concerns regarding acetaminophen. Evidence on the use of nonsteroidal…

View details →DOI: 10.1371/journal.pmed.1005063
Negative / Null Result ReportMedicine

Ascending aortic dilation and aortic regurgitation - a neglected problem among single-ventricle patients after Fontan palliation.

Kowalczyk, Kowalik, Kowalski et al. · 2026 · Cardiology journal

The Fontan procedure revolutionized the management of univentricular heart physiology but is associated with long-term complications. Although pulmonary vascular disease, atrioventricular valve regurgitation, and ventricular dysfunction…

View details →DOI: 10.5603/cj.109556
Negative / Null Result ReportMedicine

Association Between the Time Elapsed Since the Last Dental Visit and Prevalent Diseases in Peruvian Older Adults.

Quiroz-Silva, Quispe-Hinostroza, Palacios-Cortez et al. · 2026 · Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry

To assess the association between the time since the last dental visit and the prevalent systemic diseases among older Peruvian adults in 2023. A cross-sectional secondary analysis was conducted using data from the 2023 Demographic and…

View details →DOI: 10.1111/scd.70178
Negative / Null Result ReportMedicine

From Lungs to Vascular Health: Airflow Obstruction, Not Lung Function Decline, Predicts Atherosclerosis Progression Independent of Smoking Status.

Henríquez-Beltrán, Gracia-Lavedan, Sánchez-Cucó et al. · 2026 · Archivos de bronconeumologia

To prospectively evaluate the relationship between 4-year changes in lung function and the progression of subclinical atherosclerosis among 1623 middle-aged adults with at least one cardiovascular risk factor participating in ILERVAS, and…

View details →DOI: 10.1016/j.arbres.2026.04.012
Negative / Null Result ReportMedicine

Clinical significance of ventricular ectopy and development of dilated cardiomyopathy in Irish wolfhound dogs.

Post, Bell, Abrams et al. · 2026 · Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology

Cardiac disease is the second leading cause of death in Irish wolfhound (IW) populations (15.27%). Dilated cardiomyopathy (DCM) is a common hereditary disease in IWs. No correlation between ventricular premature complexes (VPCs) and DCM…

View details →DOI: 10.1016/j.jvc.2026.04.003
Negative / Null Result ReportMedicine

Prevalence and associated factors of intestinal parasitic infections in the school children of Sarlahi, Nepal.

Lama, Subedi, Parajuli · 2026 · Parasite epidemiology and control

A large proportion of the global population is affected by intestinal parasitic infections (IPIs) caused by protozoa and helminths. These infections lead to intestinal inflammation, malabsorption, and nutritional deficiencies, ultimately…

View details →DOI: 10.1016/j.parepi.2026.e00508
Negative / Null Result ReportMedicine

Incidence, microbial profile and antimicrobial resistance trends of CLABSI in adult ICUs: a longitudinal prospective study.

Anand, Sarfraz, Thakuria et al. · 2026 · Iranian journal of microbiology

Central line-associated bloodstream infections (CLABSIs) remain a major cause of healthcare-associated mortality, prolonged hospitalization, and increased healthcare costs, especially in resource-poor settings where surveillance data are…

View details →DOI: 10.18502/ijm.v18i1.20905
Negative / Null Result ReportMedicine

Magnetic resonance imaging of dogs with cervical disease revealed a higher proportion of intervertebral disk disease in small dogs and neoplasia in large dogs.

Darrah, Spence · 2026 · American journal of veterinary research

To compare the proportion of lesions identified on cervical MRI in dogs based on weight. Medical records from a tertiary referral hospital were reviewed for dogs that underwent cervical MRI to investigate clinical signs consistent with…

View details →DOI: 10.2460/ajvr.25.12.0450
Negative / Null Result ReportMedicine

Associations Between Apparent Diffusion Coefficient Values and Histopathologic Prognostic Factors in Breast Cancer: A Retrospective Study.

Mahdavi Sabet, Zeinalkhani, Forghani et al. · 2026 · International journal of breast cancer

This study is aimed at investigating the correlation between apparent diffusion coefficient (ADC) values obtained from diffusion-weighted imaging (DWI) and prognostic factors in breast cancer. We hypothesized that lower ADC values would be…

View details →DOI: 10.1155/ijbc/5114852
Negative / Null Result ReportMedicine

Natural sugar-source associations of Culicoides biting midges (Diptera: Ceratopogonidae) in a Kansas tallgrass prairie.

Markwardt, Olds, Shults et al. · 2026 · Journal of medical entomology

Culicoides Latreille is a diverse genus of approximately 1,300 species of small biting flies found across the globe, containing numerous species of medical and veterinary importance. Many diseases associated with Culicoides have no…

View details →DOI: 10.1093/jme/tjag065
Negative / Null Result ReportMedicine

Closeness of Social Media Contacts and Loneliness Among US Adults: A Nationally Representative Study.

Primack, Kim, Koneru et al. · 2026 · Public health reports (Washington, D.C. : 1974)

Loneliness is strongly linked to morbidity and mortality. While social media use has been associated with increased loneliness among adolescents, little research has examined this association among adults. It is also not clear whether it…

View details →DOI: 10.1177/00333549261443288