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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20227 results in Negative / Null Result Report · page 199 of 675

Negative / Null Result ReportMedicine

A study on the environmental characteristics and social support for physical activity among adolescents: implications for public health nursing.

Guo, Zhou, Guo et al. · 2026 · Frontiers in public health

To investigate the distribution patterns of physical activity levels, perceptions of physical activity and the social support environment among secondary school students; to examine the associations between students' physical activity…

View details →DOI: 10.3389/fpubh.2026.1835941
Negative / Null Result ReportMedicine

Cross-Sectional and Longitudinal Associations between Dietary Variety Score and Hippocampal and Grey Matter Volume Changes among Community-Dwelling Older Japanese Adults: Findings from the NEIGE Cohort.

Ohaku, Murayama, Machida et al. · 2026 · Journal of epidemiology

Dietary diversity is associated with enhanced cognitive function and reduced dementia risk among older adults; however, its relationship with structural brain ageing remains unclear. We examined cross-sectional and longitudinal…

View details →DOI: 10.2188/jea.je20250722
Negative / Null Result ReportMedicine

Co-detection of human papillomavirus and human herpesvirus in women from Yunnan, China: associations with cervical lesion severity.

Wei, Huang, Huang et al. · 2026 · BMC infectious diseases

Human papillomavirus (HPV) is necessary but not sufficient for cervical carcinogenesis. Human herpesviruses (HHVs) may act as cofactors, yet evidence is inconsistent. We assessed HPV genotypes, HHVs, and their co-detection patterns across…

View details →DOI: 10.1186/s12879-026-13751-3
Negative / Null Result ReportMedicine

Frailty dimensions and cognitive function in relation to dual-task cost: A multidomain analysis in community-dwelling older adults.

Heyzer, Low, Tan et al. · 2026 · The Journal of frailty & aging

Dual-task cost (DTC) is the performance decline observed during simultaneous motor and cognitive tasks. It is associated with cognitive and physiological vulnerability. However, it remains unclear how specific frailty dimensions and…

View details →DOI: 10.1016/j.tjfa.2026.100166
Negative / Null Result ReportMedicine

Patient Trust in Healthcare Providers among People on Methadone Maintenance Treatment Using Methamphetamine in Vietnam.

Vu, Nguyen, Nguyen et al. · 2026 · Substance use & misuse

Patient trust in healthcare providers (PTP) is critical for improving treatment adherence and outcomes in substance use disorders. As concurrent opioid and methamphetamine use increasingly complicates methadone maintenance treatment (MMT),…

View details →DOI: 10.1080/10826084.2026.2676993
Negative / Null Result ReportMedicine

Association of Race and Ethnicity With Computed Tomography Head Utilization in Children Presenting to the Emergency Department With an Unprovoked Seizure.

Kannikeswaran, Sivaswamy, Przyklenk et al. · 2026 · Pediatric neurology

Although not routinely recommended, computed tomography (CT) head are frequently performed in children presenting to emergency department (ED) with seizures. Racial and ethnic disparities have been reported in pediatric ED imaging. Our…

View details →DOI: 10.1016/j.pediatrneurol.2026.05.005
Negative / Null Result ReportMedicine

Chemical, Biological, Radiological, and Nuclear (CBRN) Disaster Preparedness among Anesthesiologists: A Multidomain Cross-Sectional Study.

Gondode, Duggal, Malviya et al. · 2026 · Disaster medicine and public health preparedness

To assess the current levels of knowledge, attitudes, practices (KAP), and institutional support regarding Chemical, Biological, Radiological, and Nuclear (CBRN) disaster preparedness among anesthesia professionals in India, and to…

View details →DOI: 10.1017/dmp.2026.10312
Negative / Null Result ReportMedicine

Infant social withdrawal with parents and strangers-The role of parental sensitivity and depression.

Rudling, Stuart, Smith-Nielsen et al. · 2026 · The British journal of developmental psychology

Infant social withdrawal is an early indicator of infant distress linked to adverse socio-emotional development. We hypothesized that parental sensitivity moderates an association between parental depression (PPD) and infant social…

View details →DOI: 10.1111/bjdp.70054
Negative / Null Result ReportMedicine

Association between periodontal and geriatric health: a cross-sectional study.

Müller, Deschner, Mohr et al. · 2026 · Clinical oral investigations

This cross-sectional study investigated the association between periodontal status and geriatric health parameters, a relationship that has received little attention in research to date. The periodontal health of 51 geriatric patients was…

View details →DOI: 10.1007/s00784-026-06938-0
Negative / Null Result ReportMedicine

Diagnostic performance of computed tomography colonography following incomplete colonoscopy and its associated factors: A single-centre retrospective study.

Mohd Hayati, Abdul Wahid, Shamsidi et al. · 2026 · The Medical journal of Malaysia

Incomplete colonoscopy presents an important clinical challenge, as segments of the colon that are not visualised may contain significant pathology. Computed tomography colonography (CTC) provides a minimally invasive alternative for…

Negative / Null Result ReportMedicine

A real-world data analysis of the impact of clonal hematopoiesis of indeterminate potential on therapeutic efficacy and adverse events of immune checkpoint inhibitors.

Fujita, Ishibashi, Aoyama et al. · 2026 · Cancer

Clonal hematopoiesis of indeterminate potential (CHIP) has been implicated in systemic inflammation. Although immune checkpoint inhibitors (ICIs) have transformed cancer care, their response rates remain modest, and some patients…

View details →DOI: 10.1002/cncr.70398
Negative / Null Result ReportMedicine

Impact of ABCB1 (rs1045642) polymorphism on antipsychotic-induced extrapyramidal symptoms in Egyptian patients with schizophrenia.

Ahmed, Moawad, Tarek et al. · 2026 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

The ABCB1 polymorphisms may influence risperidone-induced extrapyramidal symptoms (EPS) in schizophrenia. This cross-sectional study examined the relationships among ABCB1 variants, clinical factors, and objective, subjective EPS in 150…

View details →DOI: 10.1016/j.fct.2026.116181
Negative / Null Result ReportMedicine

MRI-based classification of pes anserinus tendon variations and their clinical implications in non-traumatic knees.

Çavuş, Aktürk, Argalı Deniz et al. · 2026 · Folia morphologica

The pes anserinus (PA) is a morphologically variable structure whose in vivo tendon configurations remain incompletely characterized on routine MRI. This study aimed to define the typical tritendinous configuration of the PA, identify…

View details →DOI: 10.5603/fm.111983
Negative / Null Result ReportMedicine

An Observational Study on Impact of Interim Obturators in COVID-19-Associated Mucormycosis.

Chittamuru, Vengamma, Priya et al. · 2026 · Journal of maxillofacial and oral surgery

During the second wave of COVID-19 pandemic, there was surge in reporting of COVID-19-associated mucormycosis cases. Government of India declared rhino-orbito-cerebral mucormycosis as a notifiable disease. Managing this condition posed a…

View details →DOI: 10.1007/s12663-024-02120-9
Negative / Null Result ReportMedicine

Association Between Early Versus Delayed Outpatient Follow-Up After Hospital Discharge and Short-Term Healthcare Utilization Among ICU Survivors.

Oletu, Oladimeji, Osueni et al. · 2026 · Cureus

Intensive care unit (ICU) survivors experience high rates of healthcare utilization after hospital discharge, including readmissions and emergency department (ED) visits. Timely outpatient follow-up has been proposed to improve care…

View details →DOI: 10.7759/cureus.107746
Negative / Null Result ReportMedicine

Body fat percentage and factors associated with cholesterol levels among patients at healthy choice clinic in Kathmandu, Nepal: a cross-sectional study.

Adhikari, Karki, Samu · 2026 · BMC nutrition

The study of body composition and its correlation with lipid profiles are significant markers for the cardiovascular risk factors of the urban Nepali population. This study is an attempt to evaluate the percentage of body fat and determine…

View details →DOI: 10.1186/s40795-026-01378-1
Negative / Null Result ReportMedicine

Allergic Status, Long COVID, and Post-Restriction Respiratory Outcomes in Children: A Single-Center Questionnaire-Based Study.

Brindisi, Gori, Pignataro et al. · 2026 · Journal of clinical medicine

Background: The relationship between allergic status, SARS-CoV-2 infection, Long COVID, and post-restriction respiratory outcomes in children remains incompletely understood. This study aimed to explore the associations between allergic…

View details →DOI: 10.3390/jcm15103982
Negative / Null Result ReportMedicine

Emergence Angle, Marginal Bone Loss, and Radiographic Corticalization Around MIS Implants: A 5-Year Retrospective Study of Single, Splinted, and Bridge Restorations.

Wach, Kuta, Michcik et al. · 2026 · Journal of clinical medicine

Background/Objectives : Dental implants are a predictable treatment modality for missing teeth, and the crown emergence angle may affect peri-implant tissue health. This study evaluated the influence of crown emergence angle on marginal…

View details →DOI: 10.3390/jcm15103764
Negative / Null Result ReportMedicine

Prognostic Impact of PET/CT-Derived Sarcopenia in Metastatic Breast Cancer Treated with CDK4/6 Inhibitors.

Cebeci, Birsin, Jeral Evinç et al. · 2026 · Journal of clinical medicine

Objective: This study aimed to evaluate the prognostic significance of positron emission tomography/computed tomography (PET/CT)-derived sarcopenia in patients with hormone receptor-positive, HER2-negative metastatic breast cancer treated…

View details →DOI: 10.3390/jcm15103736
Negative / Null Result ReportMedicine

Dental Treatment Needs in Older Adults Undergoing Acute Geriatric Care: A Cross-Sectional Observational Study of Clinical Need and Patient-Reported Wish for Dental Treatment.

Werneburg, Schönenberg, Andernach et al. · 2026 · Journal of clinical medicine

Background/Objectives : Dental care is not routinely integrated into acute geriatric complex treatment, although older inpatients often present with substantial oral disease. This study assessed dental treatment needs, their relationship…

View details →DOI: 10.3390/jcm15103610
Negative / Null Result ReportMedicine

Reliability and patient-centered feasibility of the Gross Motor Function Measure in children diagnosed with central nervous system tumor.

Mantovani, Chagas, Horiquini-Barbosa · 2026 · Developmental neurorehabilitation

Children diagnosed with central nervous system (CNS) tumors frequently present with persistent motor impairments that compromise independence and participation. Although the Gross Motor Function Measure (GMFM-88) is widely used in…

View details →DOI: 10.1080/17518423.2026.2679487
Negative / Null Result ReportMedicine

Association Between Global Positioning System-Based Training Load and Injury Risk in Recreational Runners: A Large Prospective Study.

Cloosterman, de Vos, Willemsen et al. · 2026 · Journal of athletic training

Understanding the relationship between training load and injury in runners may provide information on how to reduce the risk of running injuries. To investigate the association between training load and injury risk in recreational runners…

View details →DOI: 10.4085/1062-6050-0030.25