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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19821 results in Negative / Null Result Report · page 195 of 661

Negative / Null Result ReportOpen accessMedicine

Impact of Sensory Re-education Paradigm on Quality of Life, Tactile Sensation, and Proprioceptive Acuity in Patients with Post-COVID-19 Polyneuropathy: A Randomized Controlled Trial.

Alsaid HM, Khadour YA, Zakaria HM et al. · 2026 · Journal of musculoskeletal & neuronal interactions

Objectives This study evaluated the effect of sensory re-education on quality of life and sensation in patients with post-COVID-19 polyneuropathy. Methods Forty patients with post-COVID-19 polyneuropathy were randomly assigned to a study…

Negative / Null Result ReportOpen accessMedicine

Foam Versus Silver-Impregnated Foam Dressings for Pediatric Tracheostomy: A Randomized Trial.

Bostancı ŞA, Önder SŞ, Sürmeli M et al. · 2026 · Laryngoscope investigative otolaryngology

Objectives Peristomal skin complications occur in up to 29% of pediatric tracheostomy patients. While foam dressings have demonstrated superiority over traditional gauze, comparative evidence regarding silver-impregnated versus standard…

View details →DOI: 10.1002/lio2.70436
Negative / Null Result ReportMedicine

The effect of stress ball use on stress, sleep quality, and comfort in individuals receiving hemodialysis: a randomized controlled trial.

Kacaroglu Vicdan A, Gibyeli Genek D · 2026 · BMC complementary medicine and therapies

Background Hemodialysis often leads to various physiological, psychological, and social challenges for individuals receiving this treatment. This study was conducted to determine the effects of stress ball use on stress, sleep quality, and…

View details →DOI: 10.1186/s12906-026-05429-9
Negative / Null Result ReportOpen accessMedicine

Carboxymethyl cellulose-based edible coatings emulsified with Lemongrass oil for enhancing the storage stability of refrigerated broiler meat.

Ahmad U, Ishaq A, Khalid N · 2026 · Food science of animal resources

The present study aimed to analyze the effects of lemongrass essential oil emulsified with carboxymethyl cellulose (CMC) based edible coating on the physicochemical characteristics, microbial status, and oxidation level of raw chicken meat…

View details →DOI: 10.1007/s44463-025-00045-6
Negative / Null Result Report

Influence of Minor Print Parameter Variations on the Mechanical Properties of Additively Manufactured Ti-6Al-4V Parts Using Laser Powder Bed Fusion

Hall J, Radtke MP, Waterman J et al. · 2026 · Preprint

Abstract Minor variations in print parameters are an inherent aspect of modern additive manufacturing (AM) processes. This study investigated the impact of 3 distinct print parameter variations in 21 combinations on the mechanical…

View details →DOI: 10.21203/rs.3.rs-9620697/v1
Negative / Null Result ReportOpen accessMedicine

Synergistic effect and resistance prevention activity of antimicrobial peptide MPX with Tulathromycin against <i>Actinobacillus pleuropneumoniae</i>.

Wang H, Wang L, Zhang W et al. · 2026 · Frontiers in microbiology

Introduction The emergence and dissemination of multidrug-resistant Actinobacillus pleuropneumoniae (APP) have significantly hindered the advancement of the swine industry. The combination of antimicrobial peptides (AMPs) with conventional…

View details →DOI: 10.3389/fmicb.2026.1802629
Negative / Null Result ReportMedicine

[Application of the "2+3" pancreaticojejunostomy in 110 cases of pancreaticoduodenectomy].

Guo SL, Chen SH, Liu H et al. · 2026 · Zhonghua wai ke za zhi [Chinese journal of surgery]

Objective: To report the outcomes and evaluate the safety of the "2+3"pancreaticojejunostomy in pancreaticoduodenectomy. Methods: This retrospective case series analyzed clinical data from 110 consecutive pancreaticoduodenectomy patients…

View details →DOI: 10.3760/cma.j.cn112139-20251116-00534
Negative / Null Result ReportOpen accessMedicine

Hyperaldosteronism in Mice Lacking the Distal Polybasic Tract of the γ-Subunit of the Epithelial Sodium Channel During Sodium Restriction.

Essigke D, Kalo MZ, Wörn M et al. · 2026 · Acta physiologica (Oxford, England)

Aims The epithelial sodium channel ENaC consists of the subunits α, β, and γ and is activated at an individual channel level by proteolytic processing. Murine γENaC contains a distal polybasic tract 186 RKRK mediating proteolytic ENaC…

View details →DOI: 10.1111/apha.70228
Negative / Null Result ReportOpen accessMedicine

Polymerizable inhibitor can reduce shrinkage stress of resin composite.

He J, Garoushi S, Lassila L et al. · 2026 · Clinical oral investigations

Objective The purpose of this study was to prepare dental resin composites (DRCs) with low shrinkage stress and limited leachable inhibitor content by incorporating a synthesized polymerizable inhibitor PBHT…

View details →DOI: 10.1007/s00784-026-06901-z
Negative / Null Result ReportOpen accessMedicine

Three-dimensional analysis of maxillary asymmetry in patients with mandibular prognathism.

Atarashi C, Osawa K, Saito D et al. · 2026 · Maxillofacial plastic and reconstructive surgery

Background Jaw deviation is a common feature of skeletal mandibular prognathism and often extends to the maxilla, complicating diagnosis and treatment planning in surgical orthodontic treatment. Since occlusion and maxillary morphology…

View details →DOI: 10.1186/s40902-026-00506-y
Negative / Null Result ReportOpen accessMedicine

Development of engineered magnetic liposome/exosome hybrid as a novel caffeine nanocarrier for restraining liver fibrosis induced in rats.

Elakkad YE, Refai H, Ahmed HH et al. · 2026 · Scientific reports

Liver fibrosis, a severe health issue linked to liver injury, inflammation, and cell death, often progresses to liver cancer without effective treatments. In this study, an exosome-nanoliposome hybrid loaded with caffeine (Caff) was…

View details →DOI: 10.1038/s41598-025-31169-w
Negative / Null Result ReportOpen accessMedicine

Determining the Optimal Volume of Ropivacaine Combined with Dexmedetomidine for Programmed Intermittent Epidural Bolus in Labor Analgesia: A Randomized Dose-Response Study.

Song C, Ni J, Liu C et al. · 2026 · Drug design, development and therapy

Background The programmed intermittent epidural bolus (PIEB) technique is effective for labor analgesia. Although ropivacaine combined with dexmedetomidine is used for epidural labor analgesia, the optimal PIEB volume for this regimen…

View details →DOI: 10.2147/dddt.s598405
Negative / Null Result ReportOpen accessMedicine

P2X7 receptor and neuroinflammation in neurodegenerative disorders: an autoradiography study with [ 18 F]JNJ-64413739.

Ashok AH, Field S, Ramakrishnan NK et al. · 2026 · Nuclear medicine communications

Background Neuroinflammation plays a crucial role in neurodegenerative disorders such as Alzheimer's disease. The P2X7 receptor (P2X7R), expressed on microglia, is involved in neuroinflammatory responses. Despite evidence of P2X7R…

View details →DOI: 10.1097/mnm.0000000000002153
Negative / Null Result ReportMedicine

Comparison of Outcomes after Minimally Invasive Transverse Distal Metatarsal Osteotomy (MITO) and Proximal Phalangeal Osteotomy for Hallux Valgus With and Without Rheumatoid Arthritis: A Matched Cohort Study.

Yoon YK, Shim DW, Kim JH et al. · 2026 · Foot & ankle international

Background There is an increasing role for joint-preserving surgery in hallux valgus (HV) management among patients with rheumatoid arthritis (RA). We compared radiologic and clinical outcomes after minimally invasive transverse distal…

View details →DOI: 10.1177/10711007261435610
Negative / Null Result ReportOpen accessMedicine

Comparative evaluation of <i>Calotropis gigantea</i> latex and sodium hypochlorite as tissue-dissolving agents - an <i>in vitro</i> study on concentration and time-dependent proficiency.

Ravi M, Annadurai P, Gupta R · 2026 · Biomaterial investigations in dentistry

Background Complete removal of organic tissue and microorganisms from the root canal system is essential for successful endodontic therapy. Sodium hypochlorite (NaOCl) remains the gold standard irrigant for its tissue-dissolving and…

View details →DOI: 10.2340/biid.v13.45992
Negative / Null Result ReportOpen accessMedicine

Radiological differentiation of succinate dehydrogenase-deficient renal cell carcinoma from renal oncocytoma and chromophobe renal cell carcinoma.

Wang G, Yu Y, Han Y et al. · 2026 · BMC cancer

Purpose To characterize the imaging features of succinate dehydrogenase-deficient renal cell carcinoma (SDH-RCC) and compare them with those of renal oncocytoma (RO) and chromophobe RCC (chRCC). Methods This retrospective two-center study…

View details →DOI: 10.1186/s12885-026-16112-0
Negative / Null Result ReportOpen accessMedicine

The effects of 8 weeks of repeated sprint training on aerobic endurance, anaerobic power, agility and explosive strength in college badminton players.

Wei C, An J, Lin Y et al. · 2026 · PeerJ

Background Badminton is a physically demanding sport requiring a combination of aerobic endurance, anaerobic power, agility, and explosive strength. Repeated sprint training (RST) has emerged as a time-efficient strategy for improving…

View details →DOI: 10.7717/peerj.21111
Negative / Null Result ReportMedicine

Laparoscopic vs. robotic cholecystectomy for patients with cirrhosis: A propensity score-matched, single center analysis.

McCabe M, Cheung Z, Mungara T et al. · 2026 · Journal of robotic surgery

Patients with cirrhosis have increased rates of gallstone formation. While laparoscopic cholecystectomy (LC) is known to be safe in cirrhosis, perioperative morbidity remains higher than the general population. Prior work has suggested…

View details →DOI: 10.1007/s11701-026-03583-3
Negative / Null Result ReportOpen accessMedicine

Some carcass and meat quality characteristics of Anatolian local and Mast geese in semi-intensive conditions.

Ürer H, Yıldırım İ, Asker G et al. · 2026 · Tropical animal health and production

In this study, meat quality characteristics of Anatolian local geese (Anser anser domesticus) and Mast geese (Anser anser) reared under semi-intensive conditions were compared. A total of 100 geese were used: 50 from each breed, 25 males…

View details →DOI: 10.1007/s11250-026-05076-9
Negative / Null Result ReportOpen accessMedicine

The Efficacy and Safety of Dehydrated Alcohol Versus Lauromacrogol for Sclerotherapy of Simple Renal Cysts: A Retrospective Comparison Study.

Dong C, Xu S · 2026 · Health science reports

Background and aims Dehydrated alcohol and lauromacrogol are the predominant sclerosing agents employed in cyst ablation. A clear determination of the therapeutic effects comparison between the two is still lacking. This study evaluates…

View details →DOI: 10.1002/hsr2.72475
Negative / Null Result ReportMedicine

Intermittent hemodialysis with regional citrate anticoagulation vs. priming heparin and pre-dilution HDF in patients at Risk Of Bleeding in Nephrology (the ROBIN randomized control trial).

Moranne O, Gerbal M, Chkair S et al. · 2026 · Blood purification

Introduction This single center randomized controlled trial (NCT03562754) compared pre-diluted IHDF (PIHDF) without systemic anticoagulation and the Prometheus system with regional citrate anticoagulation (IHD-RCA) in high-bleeding-risk…

View details →DOI: 10.1159/000552412
Negative / Null Result ReportOpen accessMedicine

The effect of spreader graft use on voice in rhinoplasty cases: a prospective randomized controlled study.

Ulkumen B, Mutlu S, Celik O · 2026 · Brazilian journal of otorhinolaryngology

Objective This study aimed to evaluate the impact of spreader graft placement during cosmetic rhinoplasty on both objective acoustic measures and subjective voice quality. Methods In this prospective, double-blind, controlled study,…

View details →DOI: 10.1016/j.bjorl.2026.101847
Negative / Null Result ReportMedicine

Association between short (≤ 30-day) dual antiplatelet therapy and 1-year major adverse cardiac events after drug-coated balloon-based non-stent percutaneous coronary intervention following optimal lesion preparation: a propensity score-based cohort study.

Kuroda S, Sawada T, Yui R et al. · 2026 · Cardiovascular intervention and therapeutics

Drug-coated balloon (DCB)-based non-stent percutaneous coronary intervention (PCI) may allow shorter dual antiplatelet therapy (DAPT), but whether a ≤ 30-day regimen is associated with worse outcomes remains unclear, particularly in…

View details →DOI: 10.1007/s12928-026-01312-z