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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21253 results · page 188 of 709

Negative / Null Result ReportMedicine

Paraesophageal hernia repair is associated with similar safety and efficacy results in octogenarians as compared to younger patients.

Barekatain, Simon, Lyons et al. · 2026 · Surgical endoscopy

National database studies suggest elective paraesophageal hernia (PEH) repair in octogenarians is safe but provide limited detail on operative strategy and long-term symptom outcomes. We evaluated perioperative outcomes, operative…

View details →DOI: 10.1007/s00464-026-12944-w
Negative / Null Result ReportMedicine

Cryoprecipitate utilization in the neonatal intensive care unit: a single-center review.

Stoeckel, Soule-Albridge, Feldman et al. · 2026 · Journal of perinatology : official journal of the California Perinatal Association

Significant variability exists in the indications for and dosing of cryoprecipitate transfusions. We examined cryoprecipitate transfusions in neonates with a focus on indications, dosing, and the incidence of multi-donor exposure. In this…

View details →DOI: 10.1038/s41372-026-02740-8
Negative / Null Result ReportMedicine

Clinical correlates of ocular dominance in post-facial paralysis synkinesis.

Kapur, Henry, Lee et al. · 2026 · Journal of plastic, reconstructive & aesthetic surgery : JPRAS

We aimed to explore the relationship between ocular dominance and synkinesis severity. Through phone interviews and a web-based survey, patients were asked to test their ocular dominance via the Miles test. Additionally, patients were…

View details →DOI: 10.1016/j.bjps.2026.05.041
Negative / Null Result ReportMedicine

Single anastomosis duodeno-ileal bypass with sleeve gastrectomy in the United States: has increased volume impacted safety?

Ballato, Shenoy, Le Gardeur De Tilly et al. · 2026 · Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

Originally described in 2007, the single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) was only endorsed by the American Society for Metabolic and Bariatric Surgery in 2020. Since then, the procedure has grown…

View details →DOI: 10.1016/j.soard.2026.05.011
Negative / Null Result ReportMedicine

Novel Simulation-based Awake Fiberoptic Intubation Curriculum: Pilot Study.

Haas, Fredette, Murphy et al. · 2026 · The western journal of emergency medicine

Awake fiberoptic intubation is a critical skill of emergency physicians in scenarios where rapid sequence intubation may be impossible or catastrophic. While the equipment to perform awake fiberoptic intubation has become more readily…

View details →DOI: 10.5811/westjem.50778
Negative / Null Result ReportMedicine

Difference in outcomes between right and left posterior descending artery percutaneous coronary intervention: an Australian statewide registry analysis.

Rahman Zahin, Batchelor, Brennan et al. · 2026 · The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology

Percutaneous coronary intervention (PCI) is an important treatment for coronary artery disease, and coronary dominance may influence procedural risk. PCI to a left-sided posterior descending artery (L-PDA) occurs in the setting of…

View details →DOI: 10.1186/s43044-026-00755-2
Negative / Null Result ReportMedicine

Clinical characteristics and outcomes of tandem lesions involving internal carotid artery occlusion and distal middle cerebral artery occlusion.

Tomari, Lillicrap, Garcia-Esperon et al. · 2026 · Clinical neurology and neurosurgery

Tandem lesions involving internal carotid artery occlusion (ICAO) and distal middle cerebral artery occlusion (MCAO) are rare, and evidence regarding their clinical characteristics, management strategies, and outcomes remains limited. We…

View details →DOI: 10.1016/j.clineuro.2026.109515
Negative / Null Result ReportMedicine

Laboratory evaluation of mixed-species biofilm formation by Streptococcus mutans and Lactobacillus casei on three dental resin-based restorative materials.

Conner, AbdulAzees, Chen et al. · 2026 · American journal of dentistry

To evaluate the biofilm-forming potential of mixed-species bacteria on three commercially available dental restorative composites and compare their resistance to biofilm accumulation. Given the increasing emphasis on bioactive and…

Negative / Null Result ReportMedicine

Management of Rope Friction Injuries of the Hand.

Evin, Parlak, Okan et al. · 2026 · Annals of plastic surgery

Rope friction injuries result from rapid, repetitive contact with coarse ropes or chains, causing combined mechanical and thermal damage. These injuries commonly affect young individuals during activities such as tug-of-war, climbing, air…

View details →DOI: 10.1097/sap.0000000000004795
Negative / Null Result ReportMedicine

Profile of deliberate self-poisoning admissions in KwaZulu-Natal Province, South Africa (2018 - 2023) and the impact of COVID-19.

Pillay · 2026 · South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

Deliberate self-poisoning (DSP) is a common method of attempted suicide globally, particularly among young adults and women. In South Africa (SA), DSP is the second most frequent method of attempted suicide, after hanging. The COVID-19…

View details →DOI: 10.7196/samj.2026.v116i1.3710
Negative / Null Result ReportMedicine

Sensory Organization and Postural Control Strategies During Quiet Standing in People with Acute Low Back Pain: A Case-Control Study.

Fatehi Peykani, Saadat, Monjezi et al. · 2026 · The archives of bone and joint surgery

This study aimed to compare posturographic measures between acute low back pain patients (LBP) and healthy controls. A total of 20 participants with acute LBP were compared with a group of matched, healthy participants. Sensory…

View details →DOI: 10.22038/abjs.2025.85252.3885
Negative / Null Result ReportMedicine

First Covid-19 Vaccination Rates Among Pregnant Tennessee Women by Month of Conception and Urbanization Level: March 2021 - November 2021.

Valenzuela, Driscoll, Harvey et al. · 2026 · Journal of Appalachian health

Throughout the pandemic, COVID-19 vaccination coverage was lower for the general population living in rural counties than in urban counties. In Tennessee (TN), COVID-19 vaccinations became available to pregnant women in March 2021. Little…

View details →DOI: 10.13023/jah.0801.07
Negative / Null Result ReportMedicine

MRI Evaluation of Graft Remodeling After Transphyseal Anterior Cruciate Ligament Reconstruction in Pediatric Patients: A 5-Year Follow-up.

de Pesters, Staali, Laval et al. · 2026 · Orthopaedic journal of sports medicine

Anterior cruciate ligament (ACL) reconstruction (ACLR) is increasingly performed in children and adolescents, yet mid- to long-term graft ligamentization remains poorly understood. To characterize the magnetic resonance imaging (MRI)…

View details →DOI: 10.1177/23259671261447204
Negative / Null Result ReportMedicine

VR preoperative education with sensory information alleviates perioperative anxiety and enhances delivery experience in primiparas undergoing cesarean section: a randomized controlled trial.

Ran, Wei, Huang et al. · 2025 · Frontiers in psychology

To investigate the effectiveness of a VR preoperative education program with sensory information support in reducing perioperative anxiety and improving the delivery experience among primiparas undergoing cesarean section (CS). A total of…

View details →DOI: 10.3389/fpsyg.2025.1648706
Negative / Null Result ReportMedicine

Thoracic Duct Branch Identification Is Comparable Between T2-W 3D Fat-Suppressed Magnetic Resonance Imaging and Computed Tomography Lymphangiography in Normal Dogs.

Griffith, Hecht, Lux et al. · 2026 · Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association

In dogs with chylothorax that are refractory to medical management, surgical intervention is often recommended. Computed tomographic lymphangiography (CTL) is the most commonly used preoperative imaging study, but it has the disadvantages…

View details →DOI: 10.1111/vru.70198
Negative / Null Result ReportMedicine

Stool Microbiota, Metabolites, and Fecal Incontinence in Women.

Arya, Kashyap, Carnes et al. · 2026 · Urogynecology (Philadelphia, Pa.)

Stool metabolites influencing gut motility and sensation may contribute to fecal incontinence (FI). The objective of this study was to test whether FI is associated with higher levels of butyrate and Clostridiales taxa in stool. Stool…

View details →DOI: 10.1097/spv.0000000000001885
Negative / Null Result ReportMedicine

Comparative effectiveness of tirzepatide versus GLP-1 receptor agonists on the risk of venous thromboembolism in patients with obesity: a real-world cohort study.

Wu, Lee, Huang et al. · 2026 · Frontiers in medicine

Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), represents a major cause of morbidity and mortality in patients with obesity. Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs)…

View details →DOI: 10.3389/fmed.2026.1820366
Negative / Null Result ReportMedicine

An Analysis of Thyrotropin Levels in Patients With Nonscarring Alopecia: A Single-Center Retrospective Comparative Study.

Alomary, Baker, Schell et al. · 2026 · The Journal of clinical and aesthetic dermatology

To compare thyrotropin (TSH) levels across nonscarring alopecia (NSA) subtypes-alopecia areata (AA), telogen effluvium (TE), and androgenetic alopecia (AGA)-in a primary analysis of all patients, a secondary analysis of euthyroid patients…

Negative / Null Result ReportMedicine

The Influence of Congenital Heart Defect Repair Through a Right Subaxillary Thoracotomy on Postoperative Pulmonary Function and Prognosis in Small Infants.

Wang, Li, He et al. · 2026 · Reviews in cardiovascular medicine

The influence of repair of congenital heart defect (CHD) via a right subaxillary thoracotomy (RSAT) on postoperative pulmonary function and prognosis in small infants is a key consideration. Data were collected from infants who underwent…

View details →DOI: 10.31083/rcm46570
Negative / Null Result ReportMedicine

Comparative efficacy of ripertamab, rituximab, and efgartigimod in chronic inflammatory demyelinating polyneuropathy: an exploratory real-world multicenter cohort study.

Wu, Zhou, Yin et al. · 2026 · Frontiers in immunology

To analyze and compare the efficacy of ripertamab, rituximab, and efgartigimod in patients with chronic inflammatory demyelinating polyneuropathy (CIDP), focusing on treatment response rates, relapse rates, drug safety, long-term clinical…

View details →DOI: 10.3389/fimmu.2026.1825584
Negative / Null Result ReportMedicine

Monitoring cardiac symptoms during teleprehabilitation prior to coronary artery bypass grafting: a digital cardiac counselling trial subanalysis.

van Susante, van Mierlo, Scheenstra et al. · 2026 · European heart journal. Digital health

The purpose of this subanalysis was to explore whether or not teleprehabilitation leads to worsening cardiac symptoms in patients accepted for coronary artery bypass grafting (CABG). A subgroup of patients accepted for CABG (including…

View details →DOI: 10.1093/ehjdh/ztag076
Negative / Null Result ReportMedicine

Comparison of spectral-domain optical coherence tomography biometry measurements with partial coherence interferometry optical biometry.

Yakar, Özgür · 2026 · BMC ophthalmology

This study aimed to evaluate the agreement and interchangeability between a spectral-domain optical coherence tomography (SD-OCT)-based biometer (REVO FC) and a partial coherence interferometry (PCI) device (AL Scan). This prospective…

View details →DOI: 10.1186/s12886-026-04979-3
Negative / Null Result ReportMedicine

Incidence of thoracic vertebral fracture in COVID 19 patients receiving intensive treatment for severe pneumonia.

Székely, Szabó, Kardos et al. · 2026 · Ideggyogyaszati szemle

The COVID-19 pandemic has had a complex impact on the incidence of spinal fractures. In 2020, Luigi di Filippo et al. published a surprising retrospective monocentric (in Milan) clinical study. X-rays of 114 COVID-19 infected pneumonia…

View details →DOI: 10.18071/isz.79.0197
Negative / Null Result ReportMedicine

Phacoemulsification with IOL implantation combined with goniosynechialysis and goniotomy in primary angle-closure glaucoma following failed trabeculectomy: short-term effectiveness and safety outcomes.

Zhou, Ge, Jin et al. · 2026 · Frontiers in medicine

To evaluate the short-term effectiveness and safety of Phacoemulsification with intraocular lens implantation combined with goniosynechialysis and goniotomy (PEI-GSL-GT) in eyes with prior failed trabeculectomy compared to surgically…

View details →DOI: 10.3389/fmed.2026.1842636
Negative / Null Result ReportMedicine

Comparison of the therapeutic performance of macrolide antibiotics on macrolide-resistant or macrolide-susceptible Mycoplasma pneumoniae pneumonia children.

Qiu, Chen · 2026 · Frontiers in pediatrics

This research aims to investigate the performance of macrolide antibiotics for the treatment of Mycoplasma pneumoniae pneumonia (MPP) in children with or without Mycoplasma pneumoniae (MP) resistance genes. This retrospective study…

View details →DOI: 10.3389/fped.2026.1744694