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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21697 results · page 188 of 724

Negative / Null Result Report

Britain’s Failed Attempt at Monetary and Fiscal Exceptionalism

David Marsh · 2023 · The Economists’ Voice

Abstract The autumn 2022 economic upheavals that brought down British Prime Minister Liz Truss’s government represented an ultimate extension of a high-risk exercise in British exceptionalism: the June 2016 referendum decision to leave the…

View details →DOI: 10.1515/ev-2023-0021Cited by 2
Negative / Null Result Report

Modulated stimuli demonstrate asymmetric interactions between hearing and vision

Quoc C. Vuong, Mark Laing, Anjana Prabhu et al. · 2019 · Scientific Reports

Abstract The nature of interactions between the senses is a topic of intense interest in neuroscience, but an unresolved question is how sensory information from hearing and vision are combined when the two senses interact. A problem for…

View details →DOI: 10.1038/s41598-019-44079-5Cited by 2
Negative / Null Result Report

A case report about adalimumab-induced radiologically isolated syndrome: A significant side effect of tumour necrosis factor inhibitors

Joshua Onasanya, Renée A Beach · 2021 · SAGE Open Medical Case Reports

Tumor necrosis factor-α antagonists have become a therapeutic mainstay for various inflammatory diseases including Hidradenitis Suppurativa. Despite their clinical efficacy, these medications have been associated with the rare development…

View details →DOI: 10.1177/2050313x211003057Cited by 2
Negative / Null Result Report

The small impact of p-hacking marginally significant results on the meta-analytic estimation of effect size

Juan Botella, Manuel Suero, Juan I. Durán et al. · 2021 · Anales de Psicología

La etiqueta p-hacking (pH) se refiere a un conjunto de prácticas oportunistas destinadas a hacer que sean significativos algunos valores p que deberían ser no significativos. Algunos han argumentado que debemos prevenir y luchar contra el…

View details →DOI: 10.6018/analesps.433051Cited by 2
Negative / Null Result Report

Variations in Polysomnographic Indices of Obstructive Sleep Apnea following Lingual Tonsil Hypertrophy Excision: Is the Difference Significant?

Ashraf Wahba, Khaled Abdelaal, Ayman Yehia et al. · 2022 · Medicina

Background and Objectives: Obstructive sleep apnea (OSA) is a sleep-related respiratory disorder that affects between 5% and 20% of the population. In obstructive sleep apnea, lingual tonsillar hypertrophy (LTH) has been suggested as a…

View details →DOI: 10.3390/medicina58050573Cited by 2
Negative / Null Result Report

Casp8p41: The Protean Mediator of Death in CD4 T-cells that Replicate HIV

Rahul Sampath, Nathan W. Cummins, Andrew D. Badley · 2016 · Journal of Cell Death

HIV cure is now the focus of intense research after Timothy Ray Brown (the Berlin patient) set the precedent of being the first and only person cured. A major barrier to achieving this goal on a meaningful scale is an elimination of the…

View details →DOI: 10.4137/jcd.s39872Cited by 2
Negative / Null Result Report

Failure to Replicate: A Sign of Scientific Misconduct?

Helene Hill, Joel Pitt · 2014 · Publications

Repeated failures to replicate reported experimental results could indicate scientific misconduct or simply result from unintended error. Experiments performed by one individual involving tritiated thymidine, published in two papers in…

View details →DOI: 10.3390/publications2030071Cited by 2
Negative / Null Result Report

Less risk of patellofemoral degeneration without significant clinical and survivorship difference for distal tibial tuberosity high tibial osteotomy compared to biplanar high tibial osteotomy over a mid-term follow-up

Ke Li, Hengbing Guo, Fenglong Sun et al. · 2024 · Journal of Orthopaedic Surgery

Purpose This study aims to compare the mid-term radiographic, clinical results and survivorship between distal tibial tuberosity high tibial osteotomy (DTT-HTO) and conventional biplanar medial open-wedge high tibial osteotomy (cOW-HTO).…

View details →DOI: 10.1177/10225536241273925Cited by 2
Negative / Null Result Report

Dataset of replicate Apollo sample magnetizations bearing on impacts and absence of a long-lived lunar dynamo

Rory D. Cottrell, Tinghong Zhou, John A. Tarduno · 2024 · Scientific Data

Abstract The absence or presence of a lunar paleomagnetosphere is important because it bears directly on the volatile content of the regolith and exploration targets for Artemis and other missions to the Moon. Recent paleointensity study…

View details →DOI: 10.1038/s41597-024-03626-0Cited by 2
Negative / Null Result Report

Validation of an ampicillin selection protocol to enrich for mutants of Listeria monocytogenes unable to replicate on fresh produce

Victor Jayeola, C Parsons, L Gorski et al. · 2019 · FEMS Microbiology Letters

ABSTRACT Several outbreaks of listeriosis have implicated fresh produce but genetic factors required for growth of Listeria monocytogenes on produce remain poorly characterized. Based on the fact that β-lactam antibiotics only kill…

View details →DOI: 10.1093/femsle/fnz076Cited by 2
Negative / Null Result Report

Liposomes functionalized with fungi-targeting peptide demonstrate increased interaction with Candida albicans

Ronnie LaMastro, Noel Vera-Gonzalez, Kayla Campbell et al. · 2021 · Access Microbiology

Candida albicans infections can be challenging to treat, as current antifungal drugs exhibit poor water solubility and host toxicity. To overcome these issues, new methods of drug delivery are needed. Liposomes have been shown to be an…

View details →DOI: 10.1099/acmi.cc2021.po0180Cited by 2
Negative / Null Result Report

Significant Differences and Experimental Designs Do Not Necessarily Imply Clinical Relevance: Effect Sizes and Causality Claims in Antidepressant Treatments

Iván Sánchez-Iglesias, Celia Martín-Aguilar · 2023 · Journal of Clinical Medicine

Clinical trials are the backbone of medical scientific research. However, this experimental strategy has some drawbacks. We focused on two issues: (a) The internal validity ensured by clinical trial procedures does not necessarily allow…

View details →DOI: 10.3390/jcm12093181Cited by 2
Failed Experiment Report

Four Reasons Why Heterodox Academy Failed

Nathan Cofnas · 2022 · Academic Questions

Seven years ago, under the leadership of Jonathan Haidt, Heterodox Academy set out to organize a meaningful resistance to the reigning social justice orthodoxy on campus. “Seven years later,” writes Nathan Cofnas, “you can count HxA’s…

View details →DOI: 10.51845/35.4.4Cited by 2
Negative / Null Result Report

Volcanic Activity on Venus: How Long Must We Look to Find a Smoking Gun?

Scott D. King · 2022 · Journal of Geophysical Research: Planets

Abstract While volcanic landforms attest to the numerous and varied volcanic processes on Venus, estimates of the frequency of volcanic eruptions are lacking. Constraints from volcanic resurfacing volumes can be equally satisfied by…

View details →DOI: 10.1029/2022je007208Cited by 2
Negative / Null Result Report

Statistically Convergent Difference Sequences of Complex Uncertain Variables

Sangeeta Saha, Binod Chandra Tripathy · 2022 · Journal of Uncertain Systems

The main aim of this paper is to introduce several forms of statistical convergence of difference sequences of complex uncertain variables: [Formula: see text]-statistically convergence almost surely, [Formula: see text]-statistically…

View details →DOI: 10.1142/s1752890922500106Cited by 2
Negative / Null Result Report

Degenerative lumbar changes have a statistically significant but small effect on trabecular bone score (TBS)-adjusted fracture risk (FRAX)

Malik E. Juweid, Dana Alselaibi, Hiba Abandeh et al. · 2023 · Medicine

Trabecular bone score (TBS) assesses trabecular microarchitecture at the lumbar spine and was shown to improve fracture risk prediction compared to bone mineral density (BMD) alone. We investigated whether lumbar degenerative changes (DC)…

View details →DOI: 10.1097/md.0000000000036082Cited by 2
Negative / Null Result Report

Why do we find dead bumblebees under linden trees?

Malene Kyrkjebø Vinnes, Inger Marie Aalberg Haugen, Ola Diserud et al. · 2022 · Ecological Entomology

Abstract Linden trees ( Tilia spp . ) have for a long time been associated with bumblebee ( Bombus spp . ) mortality in Europe and North America. Several explanations have been suggested for this phenomenon. This study aimed to explore to…

View details →DOI: 10.1111/een.13175Cited by 2
Negative / Null Result Report

Statistically significant chuckles: who is using humour at scientific conferences?

Stefano Mammola, Diego Fontaneto, Andrea Santangeli et al. · 2026 · Proceedings of the Royal Society B: Biological Sciences

Abstract We’ve all been there: 11.47, swamped by a long stretch of dense scientific talks at a conference. Six slides into a hyper-technical presentation, the speaker suddenly cracks a joke. The room erupts. Shoulders relax. Minds…

View details →DOI: 10.1098/rspb.2025.3000Cited by 2
Negative / Null Result Report

Will we find Martian lightning via Schumann resonances?

T. M. Esman, J. R. Espley, J. R. Gruesbeck et al. · 2023 · Frontiers in Astronomy and Space Sciences

Schumann resonances are electromagnetic resonances generally associated with lightning. If they exist on Mars, Schumann resonances are expected to resonate within the ionospheric cavity at a fundamental frequency of 7–14 Hz. We conducted a…

View details →DOI: 10.3389/fspas.2023.1162624Cited by 2
Negative / Null Result Report

From SARS to COVID-19: lessons we should have learned (but we did not)

Luciano Rodrigo Lopes, João Henrique Campos, Alison Felipe Alencar Chaves · 2022 · Journal of Evidence-Based Healthcare

In 2002, a severe acute respiratory (SARS) epidemic, caused by a coronavirus (SARS-CoV), affected a significant number of countries and was interrupted after one year, approximately. Currently, coronavirus disease 2019 (COVID-19), caused…

View details →DOI: 10.17267/2675-021xevidence.2021.e3837Cited by 2
Negative / Null Result Report

Can Infants Retain Statistically Segmented Words and Mappings Across a Delay?

Ferhat Karaman, Jill Lany, Jessica F. Hay · 2024 · Cognitive Science

Abstract Infants are sensitive to statistics in spoken language that aid word‐form segmentation and immediate mapping to referents. However, it is not clear whether this sensitivity influences the formation and retention of word‐referent…

View details →DOI: 10.1111/cogs.13433Cited by 2
Negative / Null Result Report

The wild goat of Montecristo Island: did it ever exist?

Spartaco Gippoliti · 2016 · Mammalia

Abstract It has recently been claimed by Masseti that a wild goat survived on Montecristo Island until the first half of the 20th century and that subsequent selection procedures produced a goat that did not resemble any true wild goat. In…

View details →DOI: 10.1515/mammalia-2015-0078Cited by 2