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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

750 results in Failed Experiment Report · page 18 of 25

Failed Experiment ReportMedicine

Does bone mineral mass affect medial elbow injuries in young baseball players?: evaluation using bioelectric impedance analysis.

Clucas K, Saito A · 2026 · The Physician and sportsmedicine

Background Medial elbow injuries occur in approximately one-third of all young baseball players and are characterized by injuries to the bone and cartilaginous growth plates. Bone mineral mass, a representative of bone strength, may show…

View details →DOI: 10.1080/00913847.2025.2597176
Failed Experiment ReportMedicine

Effects of Proprioceptive Attenuation with Noisy Tendon Electrical Stimulation on Adaptation to Beyond-Real Interaction.

Ogawa M, Matsumoto K, Aoyama K et al. · 2025 · IEEE transactions on visualization and computer graphics

Virtual reality (VR) enables beyond-real interactions (BRI) that transcend physical constraints, offering effective user experiences like extending a hand to grasp distant objects. However, adapting to novel mappings of BRI often reduces…

View details →DOI: 10.1109/tvcg.2025.3549562
Failed Experiment ReportOpen accessMedicine

Testing the Ingroup Advantage in Emotion Perception from Dynamic Posed and Spontaneous Expressions.

Cong YQ, Yurdum L, Fischer A et al. · 2025 · Journal of nonverbal behavior

The ingroup advantage refers to the phenomenon of emotions being more accurately recognised when expressors and perceivers share the same cultural background. Though well-documented in studies using posed facial expressions, whether the…

View details →DOI: 10.1007/s10919-025-00492-1
Failed Experiment ReportMedicine

Cardiac vagal reactivation at the onset of muscle Metaboreflex activation is not further impaired in patients with Parkinson's disease.

Sabino-Carvalho JL, Guerrero RV, Teixeira AL et al. · 2025 · Autonomic neuroscience : basic & clinical

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by non-motor symptoms and marked altered sympathetic and parasympathetic activity. However, it is currently unclear if inappropriate autonomic adjustments are…

View details →DOI: 10.1016/j.autneu.2025.103311
Failed Experiment ReportMedicine

Dimethyl fumarate treatment of primary progressive multiple sclerosis: results of an open-label extension study.

Højsgaard Chow H, Talbot J, Lundell H et al. · 2023 · Multiple sclerosis and related disorders

Introduction Dimethyl fumarate treatment is approved in Europe for patients with relapsing-remitting multiple sclerosis (MS) and in the US for relapsing forms of MS. We recently published the results of the first randomized…

View details →DOI: 10.1016/j.msard.2022.104458
Failed Experiment ReportOpen accessMedicine

A Phase II Study of Abemaciclib for Patients with Retinoblastoma-Positive, Metastatic Triple-Negative Breast Cancer.

Goel S, Jovanović B, Chu X et al. · 2025 · Clinical cancer research : an official journal of the American Association for Cancer Research

Purpose Cyclin-dependent kinase 4/6 inhibitors can significantly extend survival when given in combination with endocrine therapy in patients with hormone receptor-positive metastatic breast cancer. However, their activity has been…

View details →DOI: 10.1158/1078-0432.ccr-24-2647
Failed Experiment ReportMedicine

Add-On Prostaglandin E 1 in Venovenous Extracorporeal Membrane Oxygenation: A Randomized, Double-Blind, Placebo-controlled Pilot Trial.

Buchtele N, Schörgenhofer C, Schwameis M et al. · 2022 · American journal of respiratory and critical care medicine

Rationale: Prostaglandin E 1 (alprostadil; PGE 1 ), in addition to low-dose unfractionated heparin, increases the biocompatibility of extracorporeal systems and enhances the efficacy of artificial organs without increasing bleeding risk.…

View details →DOI: 10.1164/rccm.202110-2359oc
Failed Experiment ReportOpen accessMedicine

TRAbectedin in adVanced rEtroperitoneal well differentiated/dedifferentiated Liposarcoma and Leiomyosarcoma (TRAVELL): results of a phase II study from the Italian Sarcoma Group.

Fabbroni C, Grignani G, Vincenzi B et al. · 2024 · ESMO open

Background This is a multicentre, single-arm, phase II study aimed at further exploring the activity of trabectedin as second-/further-line treatment in retroperitoneal leiomyosarcoma (LMS) and well-differentiated/dedifferentiated…

View details →DOI: 10.1016/j.esmoop.2024.103667
Failed Experiment ReportOpen accessMedicine

Investigating the effects of antipsychotic drugs as a treatment for improving the activity of the unc-33 /Dpysl2 gene in C. elegans .

Miranda MC, Hyde J, Salazar K et al. · 2024 · microPublication biology

Prenatal stress is hypothesized to contribute to the development of schizophrenia. Lee and colleagues determined that prenatal stress in rats decreases levels of Dpysl2, which is found to be inactivated in schizophrenic patients. UNC-33 ,…

View details →DOI: 10.17912/micropub.biology.001063
Failed Experiment ReportMedicine

Neural Responses to Auditory Food Stimuli Following Cognitive Behavioral Therapy for Binge-Eating Disorder.

Chao AM, Agarwal K, Zhou Y et al. · 2024 · The International journal of eating disorders

Objective Adults with binge-eating disorder (BED), compared with those without BED, demonstrate higher blood-oxygen-level-dependent (BOLD) response to food cues in reward-related regions of the brain. It is not known whether cognitive…

View details →DOI: 10.1002/eat.24244
Failed Experiment ReportMedicine

Human skeletal muscle mitochondrial responses to single-leg intermittent or continuous cycle exercise training matched for absolute intensity and total work.

Skelly LE, MacInnis MJ, Bostad W et al. · 2023 · Scandinavian journal of medicine & science in sports

There is renewed interest in the potential for interval (INT) training to increase skeletal muscle mitochondrial content including whether the response differs from continuous (CONT) training. Comparisons of INT and CONT exercise are…

View details →DOI: 10.1111/sms.14332
Failed Experiment ReportMedicine

Does treating emotional memories come at a price? Effects of single-session EMDR, imaginal exposure, and imagery rescripting on forced-choice recognition of event details in healthy adults - a laboratory study.

Aleksic M, Ehring T, Kunze A et al. · 2025 · Behaviour research and therapy

Eye Movement Desensitization and Reprocessing (EMDR), Imaginal Exposure (IE), and Imagery Rescripting (ImRs) are effective trauma-focused interventions. However, concerns persist that they may impair the accuracy of memories addressed in…

View details →DOI: 10.1016/j.brat.2025.104884
Failed Experiment Report

A field experiment assessing the roles of drought, herbivory, and local climate on cyanogenesis cline formation and local adaptation in Trifolium repens

Albano LJ, Patterson CM, Kidder EJ et al. · 2025 · Preprint

Projecting how a population will adapt to environmental changes requires a mechanistic understanding of the specific biotic and abiotic factors that impose selection on that population. In white clover ( Trifolium repens ), clines in an…

View details →DOI: 10.1101/2025.03.07.642096
Failed Experiment ReportMedicine

Contribution of individual legs to overall attachment in the adult ladybird Harmonia axyridis depends on the relative leg orientation to an external force

Saitta V, Rebora M, Piersanti S et al. · 2025 · Entomologia Experimentalis et Applicata.

This study investigates the attachment ability of harlequin ladybird, Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae), focusing on the synergic action of opposite legs, the anisotropy of adhesive organs and sexual dimorphism.…

View details →DOI: 10.1111/eea.13535
Failed Experiment ReportMedicine

The effect of increased strength on ball release speed and front foot contact-phase technique in elite male cricket fast bowlers.

Felton PJ, Shine KJ, Yeadon MR et al. · 2025 · Journal of sports sciences

Research on strength in cricket fast bowling has focused on ball release speed over technique. This study investigates how increased strength affects performance and front foot contact-phase technique during fast bowling. A planar,…

View details →DOI: 10.1080/02640414.2025.2480921
Failed Experiment ReportMedicine

Geometric, cell cycle and maternal-to-zygotic transition-associated YAP dynamics during preimplantation embryo development.

Chalifoux M, Avdeeva M, Posfai E · 2025 · Developmental biology

During the first cell fate decision in mammalian embryos, the inner cell mass cells, which will give rise to the embryo proper and other extraembryonic tissues, segregate from the trophectoderm cells, the precursors of the placenta. Cell…

View details →DOI: 10.1016/j.ydbio.2025.05.006