A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19815 results in Negative / Null Result Report · page 163 of 661
Christián C. Carman · 2025 · Centaurus
Abstract This paper investigates Kepler's initial efforts to demonstrate the bisection of Earth's orbit during his first residence in Benátky in 1600. By closely analyzing his manuscripts, I reveal the sequence of calculations he performed…
Briana N. Sprague, Anna K. Forster · 2025 · Healthcare
Objective: What types of multilevel interventions exist to improve blood pressure among community-dwelling adults aged 18+ in the United States? What is the treatment efficacy? Data Source: Peer-reviewed articles from Cochrane Library,…
Sung Il Jung, Hee Sun Park, Hae Jeong Jeon et al. · 2019 · Acta Radiologica
Background Whirlpool sign on computed tomography (CT) is pathognomic of adnexal torsion. Purpose To evaluate the visibility and common location of the whirlpool sign in adnexal torsion on CT. Material and Methods This retrospective study…
Tae-Hun Kim, Jung Won Kang · 2024 · Perspectives on Integrative Medicine
Background: Evidence mapping presents the current status of evidence on a specific field. The "Evidence Map of Acupuncture" published in 2014 gave an overall picture of the evidence on acupuncture treatments for various…
B. K. Song · 2018 · American Politics Research
In this study, I examine whether the effect of biased media can be reduced when voters have an alternative source of political information. Specifically, I investigate whether the introduction of television mitigated the effect of partisan…
Engy Ziedan, Robert Kaestner · 2021 · Evaluation Review
In this article, we provide a comprehensive, empirical assessment of the hypothesis that the Hospital Readmissions Reduction Program (HRRP) affected hospital readmissions. In doing so, we provide evidence as to the validity of prior…
Erik Paul Millstone, Elisabeth Dawson · 2020 · Archives of Public Health
Abstract On behalf of the European Food Safety Authority (EFSA), Kass and Lodi recently published a letter purporting to ‘refute’ our July 2019 analysis of EFSA’s December 2013 assessment of the risks of aspartame. We had previously…
E. Ergüder, C. Verkade, C. Ersak et al. · 2025 · Colorectal Disease
Abstract Aim To assess the outcomes of transanal advancement flap repair (TAFR) following failed ligation of intersphincteric fistula tract (LIFT) treatment for cryptoglandular anal fistulas, with a focus on healing and functional results.…
Junjie Du, Jian-Mei Li · 2010 · Heart
Dietary obesity is associated with insulin resistance and cardiovascular oxidative stress. Apocynin has traditionally been regarded as an inhibitor of NADPH oxidase but recently it was reported to be predominately an antioxidant in the…
Brandon Woo, Anushka Laha, Amelia Chen et al. · 2025 · Open Mind
Abstract In classic research, Hamlin et al. (2007) found that infants preferentially reach to agents who help others over agents who hinder others. These early findings provided evidence that infants may engage in social evaluation. There…
David Marsh · 2023 · The Economists’ Voice
Abstract The autumn 2022 economic upheavals that brought down British Prime Minister Liz Truss’s government represented an ultimate extension of a high-risk exercise in British exceptionalism: the June 2016 referendum decision to leave the…
Rif Miles Olsen · 2022 · Minerals
Between 2004 and 2018, NASA’s rover Opportunity found huge numbers of small, hematite-rich spherules (commonly called blueberries) on the Meridiani Planum of Mars. The standard oxide composition distributions of blueberries have remained…
Takashi Fujii, Shuta Maehara, Yoshimasa Fukui et al. · 2025 · Interventional Neuroradiology
Background The usefulness of CASPER, a second-generation carotid stent, for carotid artery stenosis is becoming increasingly clear. However, few studies have directly compared treatment outcomes with those of the first-generation Carotid…
TIMOTHY P. CANAVAN · 2017 · Clinical Obstetrics & Gynecology
Pregnancy failure is defined as a lack of sonographic evidence of current or expected viability. Technologic advances in ultrasound imaging continue to redefine diagnostic criteria of pregnancy failure or success. When evaluating a…
Anna Ness, Ali Zarei‐Baygi, Dave Macnevin · 2023 · Opflow
Available, effective methods of virus detection adequately address the risks in treating water for potable reuse.
Ronnie LaMastro, Noel Vera-Gonzalez, Kayla Campbell et al. · 2021 · Access Microbiology
Candida albicans infections can be challenging to treat, as current antifungal drugs exhibit poor water solubility and host toxicity. To overcome these issues, new methods of drug delivery are needed. Liposomes have been shown to be an…
Robert J. Snowden, Nicola S. Gray · 2025 · Perception
Perceptual load theory states that there are limited processing resources, but that these must always be fully employed. It has been used to predict and explain the commonly reported finding that irrelevant distractors influence behaviour…
Victor Jayeola, C Parsons, L Gorski et al. · 2019 · FEMS Microbiology Letters
ABSTRACT Several outbreaks of listeriosis have implicated fresh produce but genetic factors required for growth of Listeria monocytogenes on produce remain poorly characterized. Based on the fact that β-lactam antibiotics only kill…
Quoc C. Vuong, Mark Laing, Anjana Prabhu et al. · 2019 · Scientific Reports
Abstract The nature of interactions between the senses is a topic of intense interest in neuroscience, but an unresolved question is how sensory information from hearing and vision are combined when the two senses interact. A problem for…
Helene Hill, Joel Pitt · 2014 · Publications
Repeated failures to replicate reported experimental results could indicate scientific misconduct or simply result from unintended error. Experiments performed by one individual involving tritiated thymidine, published in two papers in…
Maria Daniela Silva, Graça Pinto, Angela França et al. · 2024 · mSystems
ABSTRACT In nature, bacteria often survive in a stationary state with low metabolic activity. Phages use the metabolic machinery of the host cell to replicate, and, therefore, their efficacy against non-dividing cells is usually limited.…
Matthew H Edney · 2024 · Cartographic Perspectives
The two standard Anglophone historiographies of the history of cartography (Skelton 1972, Harley 1987) situated the field’s origins in the early modern era, or even in the later Middle Ages. Yet “history” and “cartography” are both…
Joshua Onasanya, Renée A Beach · 2021 · SAGE Open Medical Case Reports
Tumor necrosis factor-α antagonists have become a therapeutic mainstay for various inflammatory diseases including Hidradenitis Suppurativa. Despite their clinical efficacy, these medications have been associated with the rare development…
Sebastian Wawrocki, Grzegorz Kielnierowski, Wieslawa Rudnicka et al. · 2019 · Acta Biochimica Polonica
Background: Polymorphisms in genes encoding cytokines are known to determine susceptibility to Mycobacterium tuberculosis (M.tb) infection. In particular, interleukin-18 (IL-18), an inducer of interferon-gamma (IFN-γ), playing an important…
Jonathan R. Strand, Kenneth J. Retzl · 2016 · Development and Change
ABSTRACT Using the concept of good governance, this article assesses how voting rules in the World Bank Group's primary loan facility determine members’ ability to influence the formation of winning coalitions in the Executive Board. In…
Michael J. Foster, Dana E. Veron · 2010 · Journal of the Atmospheric Sciences
Abstract Three-dimensional cloud field morphology contributes to scene-averaged cloud reflectivity, but climate models do not currently incorporate methods of identifying situations where this contribution is substantial. This work…
Ortac Guran, Hakan Oflaz, İzge Gunal · 2022 · Acta Ortopédica Brasileira
ABSTRACT Objective: To evaluate the effect of 3d printed models on surgical pre-operative planning of complex spinal deformities. Methods: In our study, five orthopedic surgeons made surgical planning of 5 patients with severe spinal…
Mika Moriwaki, Corrine Kolka Welt · 2021 · Journal of the Endocrine Society
Abstract We identified a stop-gain mutation in eIF4ENIF1 in a family in which multiple women developed primary ovarian insufficiency (POI) at approximately age 30 years. We hypothesized that the same mutation in a mouse model would…
Cheng-Hua Yang, Alex · 2015 · Journal of Air Transport Studies
Aviation safety has been affected greatly by technological improvements. A series of Ground Proximity Warning Systems (GPWSs) were developed to prevent accidents during Controlled Flight into Terrain (CFIT). This study analyzed the role of…
John W Walker, Brian M Shoemake, Danilo G Quadros et al. · 2023 · Journal of Animal Science
Abstract A sodium pentobarbital-induced sleep time study was conducted on 15 adult intact male Boer × Spanish goats selected for high (J+, n = 7) or low (J−, n = 8) juniper consumption (estimated breeding values of 13.1 ± 1.0 and −14.3 ±…