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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19815 results in Negative / Null Result Report · page 157 of 661

Negative / Null Result Report

Genome-wide association study in 404,302 individuals identifies 7 significant loci for reaction time variability

Olivia Wootton, Alexey A. Shadrin, Christine Mohn et al. · 2023 · Molecular Psychiatry

Abstract Reaction time variability (RTV), reflecting fluctuations in response time on cognitive tasks, has been proposed as an endophenotype for many neuropsychiatric disorders. There have been no large-scale genome-wide association…

View details →DOI: 10.1038/s41380-023-02292-9Cited by 5
Negative / Null Result Report

Can Generative Artificial Intelligence Outperform Self-Instructional Learning in Computer Programming?: Impact on Motivation and Knowledge Acquisition

Rafael Mellado, Claudio Cubillos · 2025 · Applied Sciences

Generative artificial intelligence tools, such as Microsoft Copilot, are transforming the teaching of programming by providing real-time feedback and personalized assistance; however, their impact on learning, motivation, and cognitive…

View details →DOI: 10.3390/app15115867Cited by 5
Negative / Null Result Report

Data protection concerns are a statistically significant reason for refusal: Exploratory study of the patient perspective on telemedicine services based on 735 gynecological surgery patients

Sascha Hoffmann, Marina Ott, Franziska Bobbert et al. · 2024 · DIGITAL HEALTH

Objective Internet-based healthcare is a crucial facet of telemedicine. Here, we examine telemedicine methods in perioperative care for gynecological surgery from a patient's perspective. We aim to understand the patients’ needs during…

View details →DOI: 10.1177/20552076241287063Cited by 5
Negative / Null Result Report

Hubble diagrams in statistically homogeneous, anisotropic universes

Theodore Anton, Timothy Clifton · 2024 · Journal of Cosmology and Astroparticle Physics

Abstract We consider the form of Hubble diagrams that would be constructed by observers in universes that are homogeneous but anisotropic, when averaged over suitably large length-scales. This is achieved by ray-tracing in different…

View details →DOI: 10.1088/1475-7516/2024/05/120Cited by 5
Negative / Null Result Report

Where is the elusive primary ebolavirus reservoir and how do we find It?

Mekala Sundaram, Nicole L Gottdenker, Patrick R Stephens · 2025 · BioScience

Abstract An enduring mystery in Ebolavirus research is what host species maintain the virus in the wild. Despite the efforts of multiple research groups over decades, no primary reservoir has ever been identified. To the contrary, finding…

View details →DOI: 10.1093/biosci/biaf050Cited by 5
Negative / Null Result Report

STABILIZER

Charlie Curtsinger, Emery D. Berger · 2013 · ACM SIGPLAN Notices

Researchers and software developers require effective performance evaluation. Researchers must evaluate optimizations or measure overhead. Software developers use automatic performance regression tests to discover when changes improve or…

View details →DOI: 10.1145/2499368.2451141Cited by 5
Negative / Null Result Report

Freedom to learn–independent campus policy: Do we really find our freedom?

Rossalina Christanti, Andreas Ari Sukoco · 2022 · Journal of Education and Learning (EduLearn)

What the job market demanded in the last few decades is overwhelming. Universities are working hard to meet the quality required by the job markets and it took a lot of effort, physically and mentally. Recently, the Minister of Education…

View details →DOI: 10.11591/edulearn.v16i2.20477Cited by 5
Negative / Null Result Report

Linking Solar and Biomass Resources to Generate Renewable Energy: Can We Find Local Complementarities in the Agricultural Setting?

Gillianne Bowman, Thierry Huber, Vanessa Burg · 2023 · Energies

Today, an energy transition is underway to tackle the problems of climate change and energy sufficiency. For this transition to succeed, it is essential to use all available renewable energy resources most efficiently. However, renewable…

View details →DOI: 10.3390/en16031486Cited by 5
Negative / Null Result Report

Comparison of AI ‐Generated and Instructor Feedback: No Significant Difference in Perceived Feedback Quality and Neither on Performance

Şeyma Çağlar‐Özhan, Perihan Tekeli, Selay Arkün‐Kocadere · 2025 · Journal of Computer Assisted Learning

ABSTRACT Background Feedback is an essential part of the educational process as it enriches students' learning experiences, provides information about their current performance, shows them what is lacking in achieving goals, and provides…

View details →DOI: 10.1111/jcal.70134Cited by 5
Negative / Null Result Report

Evaluation Methods for Statistically Dependent Text

Sarvnaz Karimi, Jie Yin, Jiri Baum · 2015 · Computational Linguistics

In recent years, many studies have been published on data collected from social media, especially microblogs such as Twitter. However, rather few of these studies have considered evaluation methodologies that take into account the…

View details →DOI: 10.1162/coli_a_00230Cited by 5
Negative / Null Result Report

Where do we expect to find deep plant roots?

G. Annie Mailloux, Mazvita Chikomo, Ying Fan · 2025 · Ecography

Plant roots have been observed up to 70 m in depth – what would compel a plant to root so deeply? Earlier work shows that the climate, soil and drainage all affect rooting depth, but with conflicting results. For example, both the deepest…

View details →DOI: 10.1002/ecog.08034Cited by 4
Negative / Null Result Report

No significant difference in intermediate key outcomes in men with low- and intermediate-risk prostate cancer managed by active surveillance

Karolina Cyll, Sven Löffeler, Birgitte Carlsen et al. · 2022 · Scientific Reports

Abstract Active surveillance (AS) is standard of care for patients with low-risk prostate cancer (PCa), but its feasibility in intermediate-risk patients is controversial. We compared outcomes of low- and intermediate-risk patients managed…

View details →DOI: 10.1038/s41598-022-10741-8Cited by 4
Negative / Null Result Report

Mining Statistically Significant Patterns with High Utility

Huijun Tang, Jiangbo Qian, Yangguang Liu et al. · 2022 · International Journal of Computational Intelligence Systems

Abstract Statistically significant pattern mining (SSPM) is to mine patterns with significance based on hypothesis test. Under the constraint of statistical significance, our study aims to introduce a new preference relation into high…

View details →DOI: 10.1007/s44196-022-00149-7Cited by 4
Negative / Null Result Report

Statistically optimal firstorder algorithms: a proof via orthogonalization

Andrea Montanari, Yuchen Wu · 2024 · Information and Inference: A Journal of the IMA

Abstract We consider a class of statistical estimation problems in which we are given a random data matrix ${\boldsymbol{X}}\in{\mathbb{R}}^{n\times d}$ (and possibly some labels ${\boldsymbol{y}}\in{\mathbb{R}}^{n}$) and would like to…

View details →DOI: 10.1093/imaiai/iaae027Cited by 4
Negative / Null Result Report

Funding source and primary outcome changes in clinical trials registered on ClinicalTrials.gov are associated with the reporting of a statistically significant primary outcome: a cross-sectional study

Sreeram V Ramagopalan, Andrew P. Skingsley, Lahiru Handunnetthi et al. · 2015 · F1000Research

Background : We and others have shown a significant proportion of interventional trials registered on ClinicalTrials.gov have their primary outcomes altered after the listed study start and completion dates. The objectives of this study…

View details →DOI: 10.12688/f1000research.6312.2Cited by 4
Negative / Null Result Report

Bit Security as Cost to Demonstrate Advantage

Keewoo Lee · 2024 · IACR Communications in Cryptology

We revisit the question of what the definition of bit security should be, previously answered by Micciancio-Walter (Eurocrypt 2018) and Watanabe-Yasunaga (Asiacrypt 2021). Our new definition is simple, but (i) captures both search and…

View details →DOI: 10.62056/an5txol7Cited by 4
Negative / Null Result Report

EasyDAM_V4: Guided-GAN-based cross-species data labeling for fruit detection with significant shape difference

Wenli Zhang, Yuxin Liu, Chenhuizi Wang et al. · 2024 · Horticulture Research

Abstract Traditional agriculture is gradually being combined with artificial intelligence technology. High-performance fruit detection technology is an important basic technology in the practical application of modern smart orchards and…

View details →DOI: 10.1093/hr/uhae007Cited by 4
Negative / Null Result Report

Does Gender Difference Play a Significant Role in Verbal and Visuospatial Working Memory Performance?

Zhi Shan Chan, Mohamad Azhari Abu Bakar · 2021 · Journal of Cognitive Sciences and Human Development

The present study investigates gender differences in working memory performance, both verbal and visuospatial working memory performance. Quasi-experimental research was conducted individually on 32 undergraduates at a public university in…

View details →DOI: 10.33736/jcshd.3744.2021Cited by 4
Negative / Null Result Report

No Significant Effect of Coulomb Stress on the Gutenberg-Richter Law after the Landers Earthquake

Víctor Navas-Portella, Abigail Jiménez, Álvaro Corral · 2020 · Scientific Reports

Abstract Coulomb-stress theory has been used for years in seismology to understand how earthquakes trigger each other. Whenever an earthquake occurs, the stress field changes, and places with positive increases are brought closer to…

View details →DOI: 10.1038/s41598-020-59416-2Cited by 4
Negative / Null Result Report

The Indirect Effect of an Internet-Based Intervention on Third-Party Disability for Significant Others of Individuals with Tinnitus

Eldré W. Beukes, Gerhard Andersson, Vinaya Manchaiah · 2024 · Audiology Research

Background: This study aimed to investigate whether Internet-based cognitive behavioural therapy intervention (ICBT) for individuals with tinnitus had an indirect effect on the third-party disability noticed by significant others (SOs).…

View details →DOI: 10.3390/audiolres14050068Cited by 4
Negative / Null Result Report

The Significant Effect of Mechanical Treatment on Ceramic Coating for Biomedical Application

Arman Shah Abdullah, Mohd Nasrun Mohd Nawi, Md Azree Othuman Mydin et al. · 2022 · Materials

Titanium and its alloys are commonly preferred materials used for biomedical implants. However, these alloys have issues related to corrosion resistance as a result of the aggressive attack of human body fluids. Several researchers have…

View details →DOI: 10.3390/ma15196550Cited by 4
Negative / Null Result Report

Convergent Microbial Community Formation in Replicate Anaerobic Reactors Inoculated from Different Sources and Treating Ersatz Crew Waste

Lisa M. Steinberg, Amanda J. Martino, Christopher H. House · 2021 · Life

Future manned space travel will require efficient recycling of nutrients from organic waste back into food production. Microbial systems are a low-energy, efficient means of nutrient recycling, but their use in a life support system…

View details →DOI: 10.3390/life11121374Cited by 4
Negative / Null Result Report

Identification of two telomere-proximal fission yeast DNA replication origins constrained by nearby cis-acting sequences to replicate in late S phase

Amna Chaudari, Joel A Huberman · 2012 · F1000Research

Telomeres of the fission yeast, Schizosaccharomyces pombe , are known to replicate in late S phase, but the reasons for this late replication are not fully understood. We have identified two closely-spaced DNA replication origins, 5.5 to 8…

View details →DOI: 10.12688/f1000research.1-58.v1Cited by 4
Negative / Null Result Report

Modeling Complex Material Interactions to Replicate and Uncover Mechanisms Driving the Performance of Steel Fiber-Reinforced Concrete Cylinders

Gili Lifshitz Sherzer, Yuri Ribakov · 2025 · Applied Sciences

This research focuses on the design and performance of Steel Fiber-Reinforced High-Strength Concrete (SFRHSC) to identify the optimal fiber content. The critical challenges involve the fiber content optimization and the effect of fiber…

View details →DOI: 10.3390/app15073445Cited by 4
Negative / Null Result Report

Experimental Study to Replicate Wood Fuel Conversion in a Downdraft Gasifier: Features and Mechanism of Single Particle Combustion in an Inert Channel

Denis Svishchev · 2022 · Applied Sciences

Downdraft gasification is a promising process of energy conversion of wood biomass. There are such fuel conversion conditions that differ favorably from conventional conditions. In such conditions, there is no pyrolysis zone in the fuel…

View details →DOI: 10.3390/app12031179Cited by 4