Negative / Null Result ReportOpen accessComputer Science
Michael Vaccaro, Mikayla Friday, Arash E. Zaghi · 2025 · Applied Sciences
Multi-agent large language models promise flexible, modular architectures for delivering personalized educational content. Drawing on a pilot randomized controlled trial with middle school students (n = 23), we introduce a two-agent GPT-4 framework in which a Profiler agent infers learner-specific preferences and a Rewrite agent dynamically adapts science passages via an explicit message-passing protocol. We implement structured system and user prompts as inter-agent communication schemas to enable real-time content adaptation. The results of an ordinal logistic regression analysis hinted that
View details →DOI: 10.3390/app15137579Cited by 9 Negative / Null Result ReportOpen accessPhysics and Astronomy
M. Rossi, Stefania Salvadori, Á. Skúladóttir et al. · 2025 · The Astrophysical Journal
Abstract The elusive properties of the first (Population III or Pop III) stars can be indirectly unveiled by uncovering their true descendants. To this end, we exploit our data-calibrated model for the best-studied ultrafaint dwarf galaxy (UFD), Boötes I, which tracks the chemical evolution (from carbon to zinc) of individual stars from their formation to the present day. We explore the chemical imprint of Pop III supernovae (SNe), with different explosion energies and masses, showing that they leave distinct chemical signatures in their descendants. We find that UFDs are strongly affected by
View details →DOI: 10.3847/1538-4357/add5e9Cited by 9 Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Floyd Khoza · 2025 · Journal of risk and financial management
Understanding the role of liquidity and leverage is crucial in assessing financial performance, particularly in the consumer goods sector. This study examined the impact of liquidity and leverage on financial performance, using a sample of 13 consumer goods firms listed on the Johannesburg Stock Exchange (JSE) from 2014 to 2024. Despite the present literature on this association, few traceable studies have investigated this phenomenon, and there is a dearth of literature in this sector. The dependent variable for this study was financial performance, and the return on assets (ROA) was employed
View details →DOI: 10.3390/jrfm18090510Cited by 9 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Chan Seok Lim, Jisun Lee, Jisun Lee et al. · 2025 · Nature Communications
SUMMARY We report the cryo-EM structures of clusters of TNF receptor family proteins, TNFR1 and BAFFR. The receptor-ligand complexes were anchored to a flat lipid layer to mimic the membrane-bound state. We observed that the TNFα-TNFR1…
View details →DOI: 10.1038/s41467-025-61271-6Cited by 9 Negative / Null Result ReportOpen accessEngineering
Yufan Zhu, Huifan Liu, Zhiqiang Yang et al. · 2026 · Theranostics
Background: Excessive inflammation and exacerbated oxidative stress are significant hallmarks of the diabetic bone microenvironment, which give rise to dysregulated immune reactions and impaired bone homeostasis, thereby hindering bone defect healing and increasing the incidence of bone nonunion.Methods: A biodegradable photothermal hybrid (SC/MTZ) was developed through the in situ self-assembly of zeolitic imidazolate framework-8 (ZIF-8) nanoparticles on tannic acid (TA)-functionalized Ti3C2Tx MXene nanosheets, which were then integrated into a methacrylated silk fibroin/carboxymethyl chitosa
View details →DOI: 10.7150/thno.130240Cited by 9 Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Goran Lalić, Dragana Trifunović · 2026 · Social Sciences
This paper examines income convergence in Europe by jointly analyzing European Union member states and Western Balkan economies over the period 2004–2023. While classical growth theory predicts that poorer economies should grow faster than richer ones, empirical evidence for Europe remains mixed, particularly when institutional and structural heterogeneity is taken into account. Using panel data techniques, the study tests for absolute and conditional β-convergence and complements this analysis with an assessment of σ-convergence. The results provide strong evidence of absolute income converge
View details →DOI: 10.3390/socsci15030180Cited by 9 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Amalie Kjær Andresen, Mathilde Sophie Felding, Margarida M. A. Sacramento et al. · 2025 · Journal of Controlled Release
Bacterial biofilms pose a significant clinical challenge due to their intrinsic resistance to antibiotics and immune clearance. Traditional systemic antibiotic therapies are often ineffective against the structured microbial communities, emphasizing the urgent need for localized and targeted drug delivery systems. Hydrogels are three-dimensional, water-rich polymeric networks, and have emerged as a versatile platform for localized delivery of antimicrobial agents, offering controlled release, biocompatibility and the potential for functionalization with bioactive components. This review explor
View details →DOI: 10.1016/j.jconrel.2025.114509Cited by 9 Negative / Null Result ReportOpen accessMedicine
Alexander N. Klishko, Jonathan Harnie, Claire E. Hanson et al. · 2025 · The Journal of Physiology
It has been suggested that during locomotion, the nervous system controls movement by activating groups of muscles, or muscle synergies. Analysis of muscle synergies can reveal the organization of spinal locomotor networks and how it…
View details →DOI: 10.1113/jp288089Cited by 9 Negative / Null Result ReportPsychology
Gorn Huvanandana, Peerayuth Charoensukmongkol · 2026 · International Journal of Workplace Health Management
Purpose Grounded in conservation of resources theory, this study investigates how digital leadership influences AI-related job insecurity, AI use anxiety, technostress, and emotional exhaustion. Innovative climate is proposed as the work…
View details →DOI: 10.1108/ijwhm-09-2025-0252Cited by 9 Negative / Null Result ReportOpen accessEngineering
Bianca Menzani, Priscille De Gea, Xavier Gidrol et al. · 2026 · Lab on a Chip
models for studying human physiology, development and disease. Their potential is very important and they have broad applications, but their impact is currently limited by persistent challenges such as incomplete maturation, batch…
View details →DOI: 10.1039/d5lc00890eCited by 9 Negative / Null Result ReportOpen accessEnvironmental Science
Forest ISBELL, A. Mori, Michel Loreau et al. · 2026 · Nature
Stability can be desirable for many natural and social systems. Temporal stability, the invariability of a system over time, can be enhanced by resisting displacement during perturbations, accelerating recovery after them, or both1–4.…
View details →DOI: 10.1038/s41586-026-10498-4Cited by 9 Negative / Null Result ReportOpen accessNeuroscience
Louis Roberts, Juho Äijälä, Florian Bürger et al. · 2026 · Nature Communications
The cortex generates diverse neural dynamics, ranging from broadband fluctuations to narrowband oscillations at specific frequencies. Here, we investigated whether broadband and oscillatory dynamics play different roles in the encoding and transmission of visual information. We used information-theoretical measures to dissociate neural signals sharing common information (i.e., redundancy) from signals encoding complementary information (i.e., synergy). We analyzed electrocorticography (ECoG) and local field potentials (LFP) in the visual cortex of human and non-human primates (macaque) to inve
View details →DOI: 10.1038/s41467-026-72444-2Cited by 9 Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Najabat Ali, Md Reza Sultanuzzaman · 2026 · Energies
This study investigates the determinants of green energy penetration in the Next Eleven (N-11) economies over the period 2000–2022, with a particular focus on the roles of foreign direct investment (FDI), green transition, governance quality, industrial growth, and urbanization. The primary objective of the study is to assess how investment flows, structural transformation, and institutional capacity jointly shape the adoption of renewable energy in fast-growing emerging economies. To achieve this goal, the study employs a second-generation panel econometric and machine-learning framework that
View details →DOI: 10.3390/en19020541Cited by 9 Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Nurcan Kilinc‐Ata, Alia Al-Fori · 2026 · Journal of risk and financial management
The intersection of financial innovation and environmental sustainability offers important opportunities for low- and middle-income (LMI) countries. This study examines the association between FinTech investment, geopolitical-economic uncertainty, urbanization, economic development, and carbon dioxide (CO2) emissions in LMI countries. CO2 emissions per capita are used as an environmental outcome indicator rather than as a direct measure of green finance. Using a panel dataset covering 2010–2021, the study applies fixed-effects panel regressions as the main empirical approach and reports one-st
View details →DOI: 10.3390/jrfm19050362Cited by 9 Negative / Null Result ReportOpen accessSocial Sciences
Peter Eshak Nashed Soliman, Reham Beram · 2025 · Journal of the Knowledge Economy
Abstract In the face of escalating unemployment rates and the pressing demand for sustainable development, this paper examines the dynamic interplay between technological innovation, information and communications technology (ICT), financial inclusion, and governance quality—key components of the knowledge-based economy and the Sustainable Development Goals (SDGs) 9 and 16—on unemployment (SDG 8) across diverse regions. Using a panel dataset spanning 2004 to 2020 for five regions (Middle East and North Africa, Sub-Saharan Africa, Latin America, Asia, and Europe), a dynamic two-step system gene
View details →DOI: 10.1007/s13132-025-02782-xCited by 9 Negative / Null Result ReportOpen accessHealth Professions
Guozheng Wang, Xiaoxia Liu, Yiming Cai et al. · 2025 · Journal of NeuroEngineering and Rehabilitation
BACKGROUND: Tai Chi (TC) is recognized for enhancing balance and postural control. However, studies on its effects on the central nervous system are limited and often involve static experiments despite the dynamic nature of TC. This study…
View details →DOI: 10.1186/s12984-025-01650-8Cited by 9 Negative / Null Result ReportOpen accessPhysics and Astronomy
Himanshu Chaudhary, Vipin Kumar Sharma, Salvatore Capozzıello et al. · 2026 · The Astrophysical Journal Supplement Series
Abstract Observational data play a pivotal role in identifying cosmological models that are both theoretically consistent and empirically viable. In this work, we investigate the level of preference for dynamical dark energy over a cosmological constant using current late-time observational datasets, including cosmic chronometers (CC), baryon acoustic oscillations from Dark Energy Spectroscopic Instrument (DESI) DR2, and different Type Ia supernova catalogs (Pantheon + , DES-Dovekie, Union3). We analyze various dynamical dark-energy models, including ω CDM, o ω CDM, ω 0 ω a CDM, logarithmic, e
View details →DOI: 10.3847/1538-4365/ae4b3fCited by 9 Negative / Null Result ReportOpen accessMedicine
Ismail Gögenür, Tobias Freyberg Justesen, Line Schmidt Tarpgaard et al. · 2026 · Journal of Clinical Oncology
PURPOSE: Neoadjuvant immune checkpoint inhibition has shown promise in localized deficient mismatch repair (dMMR) colorectal cancer, yet the optimal treatment duration, regimen, and methods for response evaluation remain undefined. This trial aimed to investigate the efficacy and safety of neoadjuvant pembrolizumab for patients with localized dMMR colon cancer. METHODS: Participants received a single cycle of pembrolizumab (4 mg/kg, max 400 mg, every-6-weeks dosing regimen), followed by a preoperative endoscopy with biopsies and surgery 3-5 weeks later. The primary end point was pathologic com
View details →DOI: 10.1200/jco-25-02274Cited by 9 Negative / Null Result ReportOpen accessHealth Professions
Ghassan M. Khairallah, Samar Al‐Hajj, Hani O. Mowafi et al. · 2025 · BMC Public Health
BACKGROUND: Healthcare workers (HCWs) are exposed to a multitude of hazards in the hospital environment, increasing their risks of sustaining injuries at a higher rate compared to workers in other sectors and resulting in substantial level…
View details →DOI: 10.1186/s12889-025-22727-yCited by 9 Negative / Null Result ReportOpen accessSocial Sciences
Brooklyn Walker, Paul A. Djupe, Brian Calfano et al. · 2025 · Perspectives on Politics
Popular narratives suggest that the effects of Christian nationalism should be more heavily concentrated among white Americans. The academic literature on Christian nationalism largely reflects this take, often asserting that it is effectively white Christian nationalism. We question such pronouncements, as they have come without systematic analysis across the broad range of issue areas needed to justify subgroup segmentations. Utilizing national oversamples of Black and Latino Christians (alongside white Christians), we assess the relationship between standard measures of Christian nationalis
View details →DOI: 10.1017/s1537592725102338Cited by 9 Negative / Null Result ReportOpen accessComputer Science
Christian Basil Omeh, Musa Adekunle Ayanwale, Lindelani Mnguni et al. · 2025 · Journal of New Approaches in Educational Research
Abstract Despite the increasing emphasis on computational literacy in higher education, we observed that many undergraduate students particularly in developing contexts struggle to master fundamental programming skills and develop critical thinking. Conventional instructional approaches often lack interactivity and personalized scaffolding, which are essential for teaching abstract programming concepts. In response to this challenge, we examined the effect of artificial intelligence (AI)-assisted problem-based learning (PBL) on students’ programming skills, critical thinking, and problem-solvi
View details →DOI: 10.1007/s44322-025-00041-0Cited by 9 Negative / Null Result ReportOpen accessDentistry
Patrick Golletz, Sissel Damsbo Jensen, Madeline Collignon et al. · 2025 · Journal of Oral Microbiology
Introduction: Coaggregation may reduce the abundance of bacteria in physiological fluids, such as saliva, as aggregated bacteria are cleared more easily than planktonic cells. This study aimed to identify Lactobacillus strains that…
View details →DOI: 10.1080/20002297.2025.2508483Cited by 9 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Lucia Scisciola, Manuela Giovanna Basilicata, Marta Belmonte et al. · 2026 · Nutrients
BACKGROUND: The heart depends on a continuous and flexible energy supply from fatty acids, glucose, and other substrates. Emerging evidence shows that gut microbiota-derived metabolites-such as trimethylamine-N-oxide (TMAO), short-chain fatty acids (SCFAs), secondary bile acids, indoles, phenylacetylglutamine (PAGln), and branched-chain amino acids-modulate cardiac metabolism and function. Although clinical evidence linking these metabolites to cardiovascular outcomes is expanding, most data remain associative, with limited causal or interventional proof. METHODS: A comprehensive narrative rev
View details →DOI: 10.3390/nu18030467Cited by 9 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Sourav Goswami, Alisha Ansari, Chetan Saraf et al. · 2026 · Nature Communications
Bifidobacteria are key health-associated members of the human gut microbiome and are widely used as probiotics, but their colonization success varies substantially between individuals, partly due to baseline microbiome composition. We…
View details →DOI: 10.1038/s41467-026-72289-9Cited by 9 Negative / Null Result ReportOpen accessNeuroscience
Marek Franěk, Jan Petružálek · 2025 · Scientific Reports
A number of eye-tracking studies have shown that viewing natural environments is associated with reduced eye movement activity compared with viewing built environments. This has been linked to the cognitive benefits of viewing nature and…
View details →DOI: 10.1038/s41598-025-07850-5Cited by 9 Negative / Null Result ReportOpen accessNeuroscience
Toshiaki Taoka, Rintaro Ito, Rei Nakamichi et al. · 2026 · Japanese Journal of Radiology
Diffusion tensor image analysis along the perivascular space (DTI-ALPS) was originally developed and defined as a noninvasive diffusion MRI method intended to evaluate glymphatic function and is now widely used in neuroimaging research. However, accumulating evidence suggests that the biological meaning of the ALPS index is more complex than initially assumed as a simple marker of glymphatic function. The ALPS index does not directly measure whole-brain fluid transport but rather reflects localized directional diffusivity based on the Brownian motion of water molecules. Its value is strongly i
View details →DOI: 10.1007/s11604-026-02035-0Cited by 9 Negative / Null Result ReportOpen accessComputer Science
Chrysanthi Melanou, Maik Beege · 2026 · Education Sciences
Generative artificial intelligence (AI) is increasingly used in higher education as an interactive tutoring partner rather than a passive information tool. While AI offers opportunities to support learning, concerns remain regarding cognitive offloading, reduced engagement, and unreflective use. Although instructional scaffolding is a well-established design principle for supporting complex learning, its role in shaping cognitive and metacognitive processes in AI-supported settings remains underexplored. This quasi-experimental pre–post study examined how varying levels of scaffolding influenc
View details →DOI: 10.3390/educsci16040651Cited by 9 Negative / Null Result ReportOpen accessMedicine
Lei Yuan, Zhe Zhao, Hongxiang Peng et al. · 2026 · Cardiovascular Diabetology
BACKGROUND: The C-reactive protein-triglyceride-glucose index (CTI) has been proposed as a novel biomarker for insulin resistance and inflammation. However, its role in the progression trajectory of cardiometabolic multimorbidity (CMM) remains unclear. We aimed to investigate the involvement of the CTI in the CMM progression trajectory. METHODS: This prospective study included 266,049 individuals from the UK Biobank, who were free of cardiometabolic diseases (CMD) at baseline. CMM was defined as the presence of two or more CMDs, including type 2 diabetes (T2D), coronary heart disease (CHD), an
View details →DOI: 10.1186/s12933-026-03174-4Cited by 9 Negative / Null Result ReportOpen accessSocial Sciences
Ngoc Anh Pham, The Anh Phan · 2025 · Journal Of Vacation Marketing
In the fast-paced world of TikTok, travel influencers craft immersive experiences that captivate followers and inspire travel intentions. This study explores how an influencer's persona—through interaction, attractiveness, and…
View details →DOI: 10.1177/13567667251382433Cited by 9 Negative / Null Result ReportOpen accessMedicine
Emanuel J. Novais, Olivia K. Ottone, Sanjana Jagannath et al. · 2026 · Bone Research
Genetic background is a major determinant of disc degeneration, a leading cause of chronic back pain and disability. Herein, we demonstrate that premature disc cell senescence contributes to early-onset degeneration in SM/J mice and test two systemic senotherapeutic strategies to mitigate it: Navitoclax (Nav.) and a cocktail of Dasatinib and Quercetin (DQ). While Nav. treatment did not improve severe degeneration in SM/J mice or senescence status, DQ-treated mice showed lower grades of degeneration and a decreased abundance of senescence markers, including p19ARF, p21, and the senescence-assoc
View details →DOI: 10.1038/s41413-026-00526-4Cited by 9 