A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19815 results in Negative / Null Result Report · page 156 of 661
Stephen Kidd · 2020 · Apeiron
Abstract The emergence of mathematical probability has something to do with dice games: all the early discussions (Cardano, Galileo, Pascal) suggest as much. Although this has long been recognized, the problem is that gambling at dice has…
Harold Pollack · 2015 · Journal of Health Politics, Policy and Law
Abstract Medicare for All, ideally implemented, could offer powerful advantages over our current health care financial system. Unfortunately, the political obstacles to such a system are formidable and are likely to remain so for decades.…
Huihui Liu, Yan-Song Gao, Xiang-Jun Chen et al. · 2016 · Scientific Reports
Abstract Creatine kinase (CK) helps maintain homeostasis of intracellular ATP level by catalyzing the reversible phosphotransfer between ATP and phosphocreatine. In humans, there are two cytosolic CK isoforms, the muscle-type (M) and the…
Natalie L. Phillips, Elysa Widjaja, Mary Lou Smith · 2020 · Epilepsia
Abstract Objective To evaluate longitudinal changes in caregiver depression, anxiety, and family relationships following resective surgery for pediatric drug‐resistant epilepsy (DRE). Methods This multicenter cohort study involved 177…
Mi Hee Kwack, Dae-Lyong Ha, Weon Ju Lee · 2022 · International Journal of Immunopathology and Pharmacology
Objectives Particulate matter (PM) is an air pollutant that can damage human skin; antioxidants have shown some efficacy in alleviating PM-induced skin inflammation. We investigated the antioxidant effects of punicalagin,…
Michelle McDonald · 2023 · Frontiers in Nephrology
The role of allograft nephrectomy (AN) in failed renal transplants is a topic of debate, owing to controversial results reported in the literature and the fact that most of the studies are limited by a retrospective design and small…
Zigmantas Gudžinskas, Laurynas Taura · 2022 · Plants
Reproductive traits are among the most important factors in determining the success of species establishment and invasion in a new area. Studies on transcontinental invasions have revealed that invasive species perform better in the…
P. FitzPatrick, K. Antczak, F. Lynch et al. · 2023 · Irish Journal of Psychological Medicine
Abstract Objectives: The COVID pandemic has been associated with poorer mental health in youth. This study aimed to evaluate any change in General Practitioner (GP) referral pattern to Child and Adolescent Mental Health (CAMH) services…
Todia P. Setiabudiawan, Philip C. Hill, Andrew R. DiNardo et al. · 2025 · Journal of Clinical Investigation
Immune correlates of protection against infection with Mycobacterium tuberculosis (Mtb) remain elusive. In this issue of the JCI , Dallmann-Sauer and authors demonstrate that lack of tuberculin skin test (TST) and interferon γ release…
Abigail T. Wilson, Steven Z. George, Joel E. Bialosky · 2019 · PAIN Reports
Abstract Introduction: Age impacts the prevalence and experience of musculoskeletal pain; however, it is unknown whether this factor impacts patient's anticipated outcomes after treatment. Objective: Using the Patient-Centered Outcomes…
Robert Philibert, Man-Kit Lei, Mei Ling Ong et al. · 2024 · Genes
The reliability of the associations of the acceleration of epigenetic aging (EA) indices with clinical phenotypes other than for smoking and drinking is poorly understood. Furthermore, the majority of clinical phenotyping studies have been…
Huanren Zhang, Yimei Hu, Xianwei Shi et al. · 2022 · Industrial Management & Data Systems
Purpose Studies have documented the distinctive advantage of innovation ecosystems in integrating and recombining heterogeneous knowledge resources across firms' boundaries. However, hierarchical governance in the form of vertical…
Valérie Francois, Matthieu Belarouci · 2021 · Journal of Small Business and Enterprise Development
Purpose This article investigates the distinctive characteristics and the performance of academic spin-offs within young innovative companies (YICs) supported by public regional agencies. Considering that academic spin-offs are…
Colleen C. Schreyer, Allisyn Pletch, Irina A. Vanzhula et al. · 2022 · International Journal of Eating Disorders
Abstract Objective Evaluating treatment efficacy solely on whether sample‐level change is statistically significant does not indicate whether clinically significant change (CSC) has occurred at the individual‐level. We assessed whether…
Zekun Cao, Jeronimo Grandi, Regis Kopper · 2021 · Frontiers in Virtual Reality
Dynamic field of view (FOV) restrictors have been successfully used to reduce visually induced motion sickness (VIMS) during continuous viewpoint motion control (virtual travel) in virtual reality (VR). This benefit, however, comes at the…
David Süss, Michael Iwersen, Vanessa Schweinzer et al. · 2019 · Reproduction in Domestic Animals
Abstract There is evidence that supplementing methionine has positive effects on uterine environment, oocyte quality and embryo development in cattle. Thus, the objective of this study was to evaluate reproductive traits of cows…
Rebecca Schennach, Hans‐Jürgen Möller, Michael Obermeier et al. · 2015 · International Journal of Methods in Psychiatric Research
Abstract Significant changes of schizophrenia patients during inpatient treatment were evalutaed and compared to established outcome criteria. The concept of reliable and clinically significant change methods was applied to three hundred…
Loubna Belaid, Umaira Ansari, Khalid Omer et al. · 2021 · Archives of Public Health
Abstract Background Universal home visits to pregnant women and their spouses in Bauchi State, northern Nigeria, discussed local evidence about maternal and child health risks actionable by households. The expected results chain for…
Yan Li, Jin-Kou Zhao, Ming Wang et al. · 2010 · Virology Journal
Abstract Background Immunoassays composed of screening and confirmation are the established algorithm to confirm HIV infection in China, with a Western blot result as the final diagnosis. Case presentation In this report, three late-stage…
Susan C. Connors, Shemiah Nyaude, Amelia Challender et al. · 2017 · Academic Medicine
Problem In medical education, evaluating outcomes from programs intended to transform attitudes or influence career trajectories using conventional methods of monitoring is often difficult. To address this problem, the authors adapted the…
Sara Ortiz-Toquero, Francisco J. Muñoz-Negrete, Gema Rebolleda · 2020 · Journal of Neuro-Ophthalmology
Background: Optic disc drusen (ODD) are a dynamic phenomenon, and their appearance, size, and relative location may change. The purpose of this study is to evaluate and quantify the longitudinal changes of buried ODD with enhanced depth…
Michael Zieger, Steffen Springer · 2021 · Pacific Conservation Biology
In nature conservation and environmental protection, there is the thesis that charismatic flagship species generate a high level of public interest that can be used for nature conservation efforts. Among other things, Google Trends has…
Eric C. Sun, Franklin Dexter, Alex Macario et al. · 2015 · Anesthesiology
AbstractAbstract In a review of payments from private insurers for five commonly billed anesthesia codes in 229 counties in the United States from 2002 through 2010, payments to anesthesiologists in more concentrated markets were not…
B Christensen, C Zhu, M Niazy et al. · 2023 · Translational Animal Science
Abstract At weaning, one hundred pigs (21 d of age; 6.96 ± 0.23 kg BW) were used to determine the effect of partially replacing soybean meal (SBM) in corn- and SBM-based nursery diets on growth performance, fecal scores, Escherichia coli…
Todd A. Astorino, Danielle Emma · 2021 · Sports
Maximal oxygen uptake (VO2max) is strongly associated with endurance performance as well as health risk. Despite the fact that VO2max has been measured in exercise physiology for over a century, robust procedures to ensure that VO2max is…
Alon Shechter, Mirae Lee, Danon Kaewkes et al. · 2023 · Journal of the American Heart Association
Background There are limited data on repeat mitral transcatheter edge‐to‐edge repair for recurrent significant mitral regurgitation (MR). Methods and Results We conducted a single‐center, retrospective analysis of consecutive patients…
Hyunjae Jeon, Sean Krysak, Steven J. Pfeiffer et al. · 2022 · International Journal of Athletic Therapy and Training
Second anterior cruciate ligament (ACL) injury has similar biomechanical risk factors as primary injury. Standard of care rehabilitation does not adequately mitigate these biomechanical risks. This study examined the effectiveness of a…
Qin Huo, Xuezhao Sun, Tingting Wu et al. · 2022 · Frontiers in Veterinary Science
Choline is an essential nutrient in ruminant diets, which contributes to the fundamental biological functions of the animal. However, choline is easily degraded in the rumen before it can be absorbed. Rumen-protected choline (RPC)…
Koji Yoshida, Lucian Krille, Steffen Dreger et al. · 2017 · Journal of Radiation Research
Abstract Computed tomography (CT) is an essential tool in modern medicine and is frequently used to diagnose a wide range of conditions, particularly in industrial countries, such as Japan and Germany. However, markedly higher doses of…
N. Hirter, A. Letko, I. M. Häfliger et al. · 2020 · Animal Genetics
Summary Entropion is a known congenital disorder in sheep presumed to be heritable but no causative genetic variant has been reported. Affected lambs show a variable inward rolling of the lower eyelids leading to blindness in severe cases.…