Negative / Null Result ReportOpen accessDecision Sciences
Giuseppe Russo, Manoel Horta Ribeiro, Tim R. Davidson et al. · 2025 · Proceedings of the ACM on Human-Computer Interaction
Journals and conferences worry that peer reviews assisted by artificial intelligence (AI), in particular, large language models (LLMs), may negatively influence the validity and fairness of the peer-review system, a cornerstone of modern…
View details →DOI: 10.1145/3757667Cited by 10 Negative / Null Result ReportOpen accessDentistry
Guowu Gan, Ruonan Chen, Peining Zheng et al. · 2026 · Frontiers in Cellular and Infection Microbiology
The oral-gut axis represents a critical bidirectional pathway linking oral microbiota to systemic health. Dysbiosis of the oral microbiome, driven by pathogens like Porphyromonas gingivalis, Fusobacterium nucleatum, Streptococcus species, and Helicobacter pylori, disrupts gut ecology via direct translocation, metabolite signaling (e.g., TMAO, SCFAs), and immune crosstalk (e.g., Th17). This leads to gut barrier dysfunction, systemic inflammation, and metabolic disturbances, contributing to diverse diseases beyond the oral cavity. Evidence supports causal links with conditions including rheumato
View details →DOI: 10.3389/fcimb.2025.1673512Cited by 10 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Tahrim Ramzan, Muhammad Shahbaz, Farooq Ahmad et al. · 2026 · New Zealand Journal of Crop and Horticultural Science
Salinity stress is a major abiotic factor that inhibits plant growth and yield. This study's objective was to evaluate how foliar applications of melatonin and ascorbic acid affected canola varieties under salt stress. The treatments of…
View details →DOI: 10.1002/nzc2.70003Cited by 10 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Ashley Rich, Ziqi Li, Alessandro De Simone et al. · 2026 · Nature Physics
Amputated salamander limbs or fish fins precisely regenerate to their pre-injury size, providing a paradigm for positional memory. Although this phenomenon has been appreciated for centuries, how position-dependent cues control tissue…
View details →DOI: 10.1038/s41567-026-03426-wCited by 10 Negative / Null Result ReportOpen accessPsychology
Isaac Davor, Francis Ohene Boateng, Franco Osei-Wusu et al. · 2026 · Cogent Education
This study examines the mediating and moderating role of metacognitive awareness in the relationship between self-regulated learning and mathematics achievement of university students in Ghana. Although self-regulated learning has attracted attention as a predictor of academic performance, few studies have examined how metacognitive awareness interacts with self-regulated learning to influence mathematics achievement in the Ghanaian context. A quantitative cross-sectional design was employed. Data were collected from 315 university students, representing a population of 3,240, using a structur
View details →DOI: 10.1080/2331186x.2026.2661434Cited by 10 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Mohamed T. El‐Saadony, Ahmed Mohamed Saad, Mahmoud Zaki Sitohy et al. · 2026 · Frontiers in Immunology
Probiotics, defined as living microorganisms, are widely recognized for their ability to positively influence the gut microbiota, an effect increasingly linked to a wide array of health benefits. They are claimed to treat or prevent conditions ranging from infant colic to cardiovascular disease, respiratory infections, and certain cancers. Since the beginning of the 21st century, consumer demand for probiotic-enriched foods has risen significantly, propelled by these health assertions. The consumption of such products has been associated with the alleviation of disorders, including irritable b
View details →DOI: 10.3389/fimmu.2025.1713426Cited by 10 Negative / Null Result ReportOpen accessMedicine
Megan L. Uhelski, Mandee K. Schaub, Felipe Espinosa et al. · 2026 · Pain
ABSTRACT: Nonselective antagonists of voltage-gated sodium channels (VGSCs) provide effective local analgesia, but systemic administration is fraught with unwanted cardiovascular and central nervous system toxicity. The development of…
View details →DOI: 10.1097/j.pain.0000000000003931Cited by 10 Negative / Null Result ReportOpen accessMedicine
Florian Kahles, Andreas L. Birkenfeld, Nikolaus Marx · 2026 · Journal of Clinical Investigation
The incretin hormone glucagon-like peptide-1 (GLP-1) exerts potent effects on glucose metabolism, prompting the development of therapeutic strategies that enhance activity of the GLP-1 receptor (GLP-1R) pathway. Inhibitors of dipeptidyl peptidase 4 (DPP-4) prolong the half-life of endogenous GLP-1 and typically achieve reductions in HbA1c of 0.5%-0.8%. However, large-scale cardiovascular (CV) outcomes trials (CVOTs) with DPP-4 inhibitors demonstrated CV safety but did not show a reduction in CV events. A second incretin-based therapeutic approach was the development of GLP-1R agonists (GLP-1RA
View details →DOI: 10.1172/jci194748Cited by 10 Negative / Null Result ReportOpen accessPhysics and Astronomy
Richard Stiskalek, Harry Desmond, Julien Devriendt et al. · 2025 · Monthly Notices of the Royal Astronomical Society
ABSTRACT The peculiar velocity field of the local Universe provides direct insights into its matter distribution and the underlying theory of gravity, and is essential in cosmological analyses for modelling deviations from the Hubble flow. Numerous methods have been developed to reconstruct the density and velocity fields at $z \lesssim 0.05$, typically constrained by redshift-space galaxy positions or by direct distance tracers such as the Tully–Fisher relation, the Fundamental Plane, or Type Ia supernovae. We introduce a validation framework to evaluate the accuracy of these reconstructions
View details →DOI: 10.1093/mnras/staf1960Cited by 10 Negative / Null Result ReportOpen accessComputer Science
Qiuhan Zhu, Xiangnan Li, Yiang Dong et al. · 2026 · Frontiers in Psychology
Generative AI tools such as ChatGPT now perform core cognitive operations—reasoning, synthesis, evaluation, and creative generation—on users' behalf, raising urgent questions for educational psychology about how AI use relates to cognitive development. Yet research on cognitive offloading has largely treated AI use as a unidimensional phenomenon, obscuring a theoretically consequential distinction: whether AI substitutes for the user's own thinking or scaffolds it. Drawing on the autonomous–dependent help typology and self-determination theory, the present study introduces and examines a disti
View details →DOI: 10.3389/fpsyg.2026.1878629Cited by 10 Negative / Null Result ReportOpen accessMedicine
Jean‐Christophe Marine, Osnat Bartok, Shira Sagie et al. · 2026 · Cell
Intratumor heterogeneity (ITH) encompasses genetic, epigenetic, transcriptional, proteomic, and immunopeptidomic diversity. Beyond genetic heterogeneity, it is increasingly clear that non-mutational heterogeneity and plasticity generate…
View details →DOI: 10.1016/j.cell.2026.03.025Cited by 10 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Chengjiao Yang, Ruici Yang, Binbin Zheng et al. · 2026 · Cell Death and Disease
Protein lactylation emerges as a pivotal metabolic rheostat, translating microenvironmental lactate flux into stable programs that orchestrate cancer treatment resistance. This review synthesizes recent advances under the framework of "Lactylation Switch in Cancer Vulnerabilities." We dissect the dominant enzymatic pathways (AARS1/2, KATs, HDACs) and non-enzymatic mechanisms (MGO/LGSH), alongside their critical structural underpinnings. Furthermore, we delineate how lactylation signals are interpreted by specific readers (e.g., TRIM33), directly reprogram non-histone protein function through s
View details →DOI: 10.1038/s41419-026-08494-7Cited by 10 Negative / Null Result ReportOpen accessPsychology
Matthew Bourke, Claudia I. Maddren, Franziska Sippel et al. · 2026 · Archives of Pediatrics and Adolescent Medicine
Importance: Understanding the within-person association between daily screen use and sleep can help clarify whether this association reflects potentially causal effects or confounding factors. Objective: To synthesize evidence on the…
View details →DOI: 10.1001/jamapediatrics.2025.6490Cited by 10 Negative / Null Result ReportOpen accessMaterials Science
Ran Dong, Yingao Ru, Xi Zhang et al. · 2026 · ACS Omega
Abstract Batch nanofabrication of complex nanostructures remains a critical challenge, restricting their translation from laboratory design to industrial application. To address this, we report a conceptual and methodological advance by…
View details →DOI: 10.1021/acsomega.6c03877Cited by 10 Negative / Null Result ReportOpen accessArts and Humanities
Gongwei Guo, Zhihui Tang, Honggang Liu · 2026 · European Journal of Education
ABSTRACT Although the proliferation of artificial intelligence (AI) and digital tools has facilitated AI‐enhanced and informal digital learning of English, traditional classroom ecology remains a central context for adolescent English‐as‐a‐foreign‐language (EFL) learners' language learning and development. Additionally, while the importance of achievement emotions among tertiary‐level EFL learners has been well established, research on retrospective outcome emotions (e.g., pride and shame) among non‐tertiary EFL learners remains scarce. As such, the study investigated whether and how language
View details →DOI: 10.1111/ejed.70859Cited by 10 Negative / Null Result ReportOpen accessEngineering
Lorenzo Tamboia, Giorgio Montinaro, Elisa Ravesio et al. · 2026 · Journal of Cleaner Production
The growing demand for sustainable energy solutions has highlighted the crucial role of lithium-ion batteries (LIBs) in the global energy transition. However, the conventional use of polyvinylidene fluoride (PVDF) binders combined with…
View details →DOI: 10.1016/j.jclepro.2026.148153Cited by 10 Negative / Null Result ReportOpen accessSocial Sciences
Ingvild Almås, Alexander W. Cappelen, Erik Ø. Sørensen et al. · 2026 · The Quarterly Journal of Economics
Abstract This article provides the first comprehensive global evidence on people’s fairness and efficiency preferences, beliefs about the sources of inequality and the efficiency cost of redistribution, and policy attitudes toward redistribution. Using a globally harmonized consequential experiment with more than 65,000 individuals across 60 countries, we show that the source of inequality plays a substantially larger role for inequality acceptance than the efficiency cost of redistribution. At the global level, implemented inequality increases by 85% when inequality is caused by merit rather
View details →DOI: 10.1093/qje/qjag044Cited by 10 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Jennifer L. Havens, Sergei L. Kosakovsky Pond, Jordan D. Zehr et al. · 2026 · Cell
Using a phylogenetic framework to characterize natural selection, we investigate the hypothesis that zoonotic viruses require adaptation prior to zoonosis to sustain human-to-human transmission. Examining the zoonotic emergence of Ebola…
View details →DOI: 10.1016/j.cell.2026.02.006Cited by 10 Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Vania Stavrakeva, JENNY TANG · 2026 · The Journal of Finance
ABSTRACT Conventional wisdom holds that lowering a home country's interest rate relative to another's will depreciate the domestic currency. We document that, at business‐cycle frequencies, U.S. forward guidance monetary policy easings had…
View details →DOI: 10.1111/jofi.70025Cited by 10 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Alicia Huerta‐Chagoya, Joohyun Kim, Ravi Mandla et al. · 2026 · The Lancet Diabetes & Endocrinology
BACKGROUND: Polygenic risk scores (PRSs) improve prediction of the development of type 2 diabetes over the use of clinical risk factors alone; however, they perform poorly in populations of non-European ancestry, limiting their global…
View details →DOI: 10.1016/s2213-8587(25)00405-xCited by 10 Negative / Null Result ReportOpen accessMedicine
Suli Yu, Zhen Pang, Hong Fang et al. · 2026 · Molecular Biomedicine
Ferroptosis, a regulated cell death modality driven by iron accumulation and lipid peroxidation, has emerged as a pivotal pathophysiological mechanism across a broad spectrum of cardiovascular diseases (CVDs), which remain the leading cause of global mortality. Although robust preclinical evidence indicates that modulation of ferroptosis attenuates myocardial and vascular injury, clinical translation is constrained by incomplete understanding of context-specific roles, the paucity of validated biomarkers, and the absence of targeted therapeutics with acceptable safety profiles. In this Review,
View details →DOI: 10.1186/s43556-026-00420-9Cited by 10 Negative / Null Result ReportOpen accessMedicine
Jiahui Xiang, Jiayi Li, Zizhao Guo et al. · 2026 · Biomarker Research
Poly (ADP-ribose) polymerase (PARP) inhibitors have emerged as a paradigm-shifting therapeutic strategy in oncology, demonstrating significant synthetic lethality in tumors characterized by homologous recombination deficiency. Due to their…
View details →DOI: 10.1186/s40364-026-00908-0Cited by 10 Negative / Null Result ReportOpen accessMedicine
Joe M. Butler, Hessel Peters Sengers, Tom D. Y. Reijnders et al. · 2025 · EBioMedicine
BACKGROUND: Knowledge of the contribution of the pathogen to the heterogeneity of the host response to infection is limited. We aimed to compare the host response in critically ill patients with a bloodstream infection (BSI). METHODS: RNA profiles were determined in blood obtained between one day before and after a positive blood culture. Differential expression and pathway analyses were performed on independent patients' samples by RNA sequencing (discovery) or microarray (validation). Additional patients were included for the discovery and validation of transcriptome classifiers of pathogen-
View details →DOI: 10.1016/j.ebiom.2025.105799Cited by 10 Negative / Null Result ReportOpen accessPsychology
Federica Pallavicini, Eleonora Francesca Orena, Lisa Arnoldi et al. · 2024 · JMIR Serious Games
BACKGROUND: Virtual reality (VR) is helpful for the management of stress and anxiety. However, current interventions have limitations related to location (ie, therapist's office or hospitals) and content (ie, virtual experiences only for relaxation). OBJECTIVE: This randomized pilot trial aims to investigate the efficacy and acceptability of a brief remote VR-based training for supporting stress and anxiety management in a sample of Italian health care workers. METHODS: A total of 29 doctors and nurses (n=21; 72% female; mean age 35.6, SD 10.3 years) were recruited and randomized to a VR inter
View details →DOI: 10.2196/50326Cited by 10 Negative / Null Result ReportOpen accessComputer Science
Mahdi Ghafourian, BILGESU SUMER, Rubén Vera-Rodríguez et al. · 2026 · Computers
Biometric recognition, as an efficient and hard-to-forge method of identification and verification, has become an indispensable part of the current digital world. Meanwhile, blockchain has been widely received by both research and industry. Researchers have started to speculate on the pros and cons when these two technologies cross paths. This paper provides a survey of the literature on the combination of blockchain and biometrics and includes a first legal analysis of this integration based on GDPR. Although the integration of blockchain technology into the biometric sector is still in its i
View details →DOI: 10.3390/computers15100716Cited by 10 Negative / Null Result ReportOpen accessMedicine
Xuanyu Qi, Guangzheng YANG, Zeqian Xu et al. · 2026 · Bone Research
Abstract Nociceptive pain is a cardinal feature of traumatic and inflammatory bone diseases. However, whether and how nociceptors actively regulate the immune response during bone regeneration remains unclear. Here, we found that neutrophil-triggered nociceptive ingrowth functioned as negative feedback regulation to inflammation during bone healing. A unique Il4ra + Ccl2 high neutrophil subset drove intense postinjury TRPV1 + nociceptive ingrowth, which in return dissipated inflammation by activating the production of pro-resolving mediator lipoxin A4 (LXA4) in osteoblasts. Mechanistically, os
View details →DOI: 10.1038/s41413-025-00481-6Cited by 10 Negative / Null Result ReportOpen accessNeuroscience
Yanyu Bao, Guoying Miao, Nannan He et al. · 2026 · Biology
Mitochondrial dysfunction is a key early pathological process in neurodegenerative diseases (NDs), leading to oxidative stress, impaired energy metabolism, and neuronal apoptosis prior to the onset of clinical symptoms. Although mitochondria represent important therapeutic targets, effective interventions targeting mitochondrial function remain limited. This review summarizes current evidence regarding the mechanisms by which melatonin protects mitochondria and evaluates its therapeutic relevance, with a primary focus on Alzheimer's disease, Parkinson's disease, and Huntington's disease-the ma
View details →DOI: 10.3390/biology15020189Cited by 10 Negative / Null Result ReportOpen accessPsychology
Anatolia Batruch, Nicolas Sommet, Frédérique Autin · 2025 · Nature Human Behaviour
Abstract Theoretical models have been developed to understand how social class influences individual thoughts, feelings and behaviours. However, the validity of these models is threatened by the prevailing use of small, non-diverse samples and flexible measurement practices. We preregistered replications of 35 key hypotheses from 17 correlational and 5 experimental studies, and collected large, quota-based or probability samples from the USA, France, Switzerland and India ( N total = 33,536). Our analysis yielded three central findings: (1) ~50% of the effects were successfully replicated; (2)
View details →DOI: 10.1038/s41562-025-02234-1Cited by 10 Negative / Null Result ReportOpen accessComputer Science
Mohammadreza Farrokhnia, Saeed Latifi, Pantelis M. Papadopoulos et al. · 2026 · International Journal of Educational Technology in Higher Education
Abstract Providing high-quality feedback on student writing is essential yet increasingly difficult due to rising class sizes and limited instructional capacity. Generative AI (GenAI) offers a promising and scalable alternative, but its effectiveness compared to traditional teacher feedback, particularly across different prompting techniques, remains uncertain. This study employed a quantitative, randomized three-group experimental design with 70 graduate students to compare the effects of teacher feedback and GenAI feedback generated using two prompting techniques: Zero-shot and chain-of-thou
View details →DOI: 10.1186/s41239-026-00579-9Cited by 10 Negative / Null Result ReportOpen accessEngineering
Junyi Yin, Jie Zhu, Shaolei Wang et al. · 2026 · Nature Communications
One-dimensional (1D) multifunctional fibers have garnered significant attention due to their advantageous geometry properties, which allows conformal interfacing with soft biological tissues and efficient charge transport. Here, we…
View details →DOI: 10.1038/s41467-026-70178-9Cited by 10 