A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
750 results in Failed Experiment Report · page 12 of 25
Celik M, Polat ME, Ceviz K et al. · 2026 · World journal of urology
Purpose Vasculogenic erectile dysfunction (ED) is associated with endothelial dysfunction and oxidative stress. This study evaluated the clinical efficacy of radial-type low-intensity extracorporeal shockwave therapy (Li-ESWT) and its…
Kim B, Lee J, Park S et al. · 2023 · Vision research
This study investigated facial skin color differences before and after makeup. Toward this goal, a photo gauge, devised with a pair of color checkers as a reference, collected face images. In addition, color calibration and a deep-learning…
Dameron LS, Bank NC, Raghava N et al. · 2026 · Journal of hand surgery global online
Purpose The primary aim was to compare postoperative complications at 90 days and 1 year following trigger finger release (TFR) in patients with versus without glucagon-like peptide-1 receptor agonist (GLP-1 RA) exposure. GLP-1 RAs are…
Park EC, Harris LM, Sigel AN et al. · 2023 · Behaviour research and therapy
Existing evidence suggests a link between physical pain and suicide, but the nature of this relationship remains unknown. To address this critical gap in knowledge, the present study leveraged a validated virtual reality (VR) suicide…
Cabrera GJ, Farías P, Sáez CG · 2026 · Journal of voice : official journal of the Voice Foundation
Introduction Parkinson's disease (PD) is frequently associated with voice and speech impairments that negatively affect communication and quality of life. Although several studies have identified vocal variables with potential clinical…
McKyton A, Marks Ohana D, Nahmany E et al. · 2023 · Current biology : CB
How will people who spent their visual lives with only rods respond to cone function restoration? Will they be able suddenly see the colors of the rainbow? CNGA3-achromatopsia is a congenital hereditary disease in which cone dysfunction…
Chidharom M, Tong M, Carlisle NB · 2024 · Visual cognition
Negative templates come from foreknowledge of distractor-features and lead to improved performance during visual search. Recent studies have better characterized the mechanisms underlying these benefits, by showing a critical role of…
López-Sagaseta J, Urdiciain A · 2025 · Scientific reports
Artificial intelligence (AI) and deep learning are making groundbreaking strides in protein structure prediction. AlphaFold is remarkable in this arena for its outstanding accuracy in modelling proteins fold based solely on their amino…
Bhat YA, Mocavini I, O’Donnell E et al. · 2026 · Preprint
The Bre1 ubiquitin conjugating enzyme catalyzes the monoubiquitylation of histone H2B-K120/K123 at promoter proximal nucleosomes, contributing to transcriptional regulation. These same nucleosomes are targeted by the yeast SWR1C chromatin…
Han S, Long NM · 2025 · Imaging neuroscience (Cambridge, Mass.)
Engagement of the retrieval state (or mode) is theorized to be a precursor to successful retrieval, but precisely when the retrieval state is engaged is unclear. Our aim in the present study is to determine the time course of retrieval…
Tamasauskiene L, Gradauskiene B · 2024 · Journal of inflammation (London, England)
Background T lymphocyte helper (Th) 2 plays the main role in pathogenesis of allergic airway diseases (AAD). Recent studies showed that interleukin (IL) 33, Th17 and Th22 also may be involved in allergic inflammation. The aim is to…
Petersen Dias A, Orsel K, Gammariello CS et al. · 2025 · Research in Veterinary Science
Digital dermatitis (DD) is a polymicrobial, multifactorial hoof disorder with an undefined etiology, and existing animal models fail to induce a fast, standardized infection in bovine skin. This study explored bacterial inoculation methods…
Holden A, Burns P, Devenny A et al. · 2026 · Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
Background Improved survival in cystic fibrosis (CF) has shifted clinical focus toward late complications, including altered body composition, bone health and cardiopulmonary fitness. The effects of Elexacaftor/Tezacaftor/Ivacaftor (ETI)…
Whyte-Fagundes P, Vance A, Carroll A et al. · 2023 · Preprint
Dravet syndrome (DS) is a severe genetic epilepsy primarily caused by de novo mutations in a voltage-activated sodium channel gene (SCN1A). Patients face life-threatening seizures that are largely resistant to available anti-seizure…
Bender O, Shemesh OA, Bar DZ · 2026 · Journal of Alzheimer's disease : JAD
The etiology of Alzheimer's disease (AD) remains a subject of intense investigation. While the 2024 Lancet Commission report attributes approximately 45% of global dementia cases to 14 modifiable risk factors, it notably excludes…
Kalkunte NG, Delabmbre TE, Sohn S et al. · 2022 · Preprint
The potential of human induced pluripotent stem cell differentiated cardiomyocytes (hiPSC-CMs) is greatly limited by their functional immaturity. Strong relationships exist between CM structure and function, leading many in the field to…
Matthew Boyea, null null, null null et al. · 2022 · John Heinrichs Scholarly & Creative Activities Day
Modern manufacturing processes increasingly demand machine driven solutions When developing robot applications in industry, programmers must be able to safely write code which is reusable, expandable, and well documented This case study…
Stepanova EV, Strube MJ, Mazur KD · 2023 · The Journal of social psychology
In two studies, participants completed an implicit attractiveness task with faces as primes varying on (a) facial features from Afrocentric to Eurocentric and (b) skin tone from dark to light, and target pictures of environmental scenes…
Shivashankar P, Agee LA, Wilson N et al. · 2025 · Journal of neuroscience methods
Background Acoustic startle response (ASR) is an involuntary reflex to an intense acoustic stimulus, characterized by rapid muscle contractions. Traditional ASR testing requires animals to be placed in spatially confining chambers to…
da Eira Silva V, Abele M, Bercovitz I et al. · 2025 · Workplace health & safety
Background The use of the N95 respirator outside work environments calls for a deeper understanding of the factors that interfere with its fitting, thus effectiveness. Here we determined how beard length influences N95 effectiveness. This…
Seojoon Park, Paul Adams, null null et al. · 2020 · John Heinrichs Scholarly & Creative Activities Day
Every person would have thought of this idea of launching aballoon high up in the sky in their youth, and that is exactlywhat we did. We filled a large elastic balloon filled withhelium and flew it high up into the sky until it popped…
Johnson B, Addolorato G, Lesch O et al. · 2023 · Frontiers in psychiatry
A core principle in the pursuit of scientific knowledge is that science is self-correcting and that important results should be replicable. Hypotheses need to be reinforced, adjusted, or rejected when novel results are obtained.…
Ariizumi T, Oike N, Murayama Y et al. · 2026 · Discover oncology
Background Giant cell tumor of bone (GCTB) is a locally aggressive tumor that rarely metastasizes, although a small subset undergoes malignant transformation. H3F3A driver mutations have been recognized as characteristic molecular features…
Lecher S, Jaisinghani N, Previti M et al. · 2026 · Preprint
MmpL proteins play an important role in the various mechanisms associated with mycobacterial virulence. Identification of interacting protein partners required for a detailed understanding of their role remains hampered because of their…
Bagińska M, Morawska-Tota M, Pałka T et al. · 2026 · Journal of clinical medicine
Background/Objectives : Bone tissue undergoes continuous remodelling processes that are closely controlled by mechanical stimuli and metabolic as well as inflammatory factors. Although the beneficial effects of regular physical activity on…
Shyam Kumar R, Chakraborty S, Jayakumar H et al. · 2026 · Molecular biology reports
Background N6-methyladenosine (m6A) modification of mRNAs through METTL3 maintains homeostasis in many cell types. The mechanism by which METTL3 complexes together with reader proteins, especially the YTH domain-containing protein, governs…
Li S, Lv C, Xie P et al. · 2026 · Clinical nuclear medicine
A 6-year-old boy presented with a 2-month history of fever of unknown origin. 18F-FDG PET/CT was performed to identify the potential source, revealing a solitary focus of abnormal radiotracer uptake in the left humerus. Bone marrow biopsy…
Karimi E, Momeni Z, Nasiri V et al. · 2026 · Diagnostic microbiology and infectious disease
Blastocystis is a genetically diverse unicellular eukaryotic intestinal parasite with no gold-standard diagnostic method. This study, conducted in Iran, is the first to directly compare Sequence-Tagged Site (STS) PCR and restriction…
Nishimura T, Kodama T, Chiba K et al. · 2026 · Physical chemistry chemical physics : PCCP
To identify factors that enhance thermochemical redox reaction efficiency, we have investigated the thermochemical properties of transition-metal-doped cerium oxide. This study examines thermodynamic parameters using vibrational entropy…
Sung K, Park M, Kweon O et al. · 2026 · Food Microbiology.
Campylobacter jejuni is a foodborne pathogen with limited ability to thrive at low temperatures. This study investigated the survival and proteomic responses of C. jejuni NCTC 11168 during prolonged storage at 4 °C, with specific focus on…