Negative / Null Result ReportOpen accessMaterials Science
Kimberly M. Sogi, Zev J. Gartner, Mark A. Breidenbach et al. · 2013 · PLoS ONE
The genome of Mycobacterium tuberculosis (Mtb) encodes nine putative sulfatases, none of which have a known function or substrate. Here, we characterize Mtb's single putative type II sulfatase, Rv3406, as a non-heme iron (II) and α-ketoglutarate-dependent dioxygenase that catalyzes the oxidation and subsequent cleavage of alkyl sulfate esters. Rv3406 was identified based on its homology to the alkyl sulfatase AtsK from Pseudomonas putida. Using an in vitro biochemical assay, we confirmed that Rv3406 is a sulfatase with a preference for alkyl sulfate substrates similar to those processed by Ats
View details →DOI: 10.1371/journal.pone.0065080Cited by 21 Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Irina Travkina, Manuela Tvaronavičienė · 2015 · Journal of Entrepreneurship and Sustainability Issues
The research paper discusses the relationship between international trade, especially export, and the economic growth, presented by GDP, in Lithuania over the period of 2000-2015 years. The analysis is started by the historical review of possible types of relationships between exports and economic growth. Furthermore, the paper presents four theoretical propositions as export-led growth (1), growth-driven export (2), a feedback relationship (3) and simple contemporaneous relationship (4). This study examines the importance of the export-led growth hypothesis for Lithuania. The testing is based
View details →DOI: 10.9770/jesi.2015.2.4(7)Cited by 21 Negative / Null Result ReportOpen accessImmunology and Microbiology
John F. Krisko, Nurjahan Begum, Caroline E. Baker et al. · 2016 · Journal of Virology
UNLABELLED: The multifunctional HIV-1 accessory protein Vif counters the antiviral activities of APOBEC3G (A3G) and APOBEC3F (A3F), and some Vifs counter stable alleles of APOBEC3H (A3H). Studies in humanized mice have shown that HIV-1…
View details →DOI: 10.1128/jvi.03275-15Cited by 21 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Neil D. Clarke, James R. Thomas, Marion Kagka et al. · 2016 · The Journal of Strength and Conditioning Research
Clarke, ND, Thomas, JR, Kagka, M, Ramsbottom, R, and Delextrat, A. No dose-response effect of carbohydrate mouth rinse concentration on 5-km running performance in recreational athletes. J Strength Cond Res 31(3): 715-720, 2017-Oral…
View details →DOI: 10.1519/jsc.0000000000001531Cited by 21 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Rebecca Fisher, David R. Fox · 2023 · Environmental Toxicology and Chemistry
The no-effect concentration (NEC) is the preferred threshold metric for single-species toxicity tests applied to derive safe concentration thresholds for contaminants in the environment for use in species sensitivity distributions.…
View details →DOI: 10.1002/etc.5610Cited by 21 Negative / Null Result ReportOpen accessPhysics and Astronomy
Wei Hu · 2013 · Social Networking
Various networks exist in the world today including biological, social, information, and communication networks with the Internet as the largest network of all. One salient structural feature of these networks is the formation of groups or communities of vertices that tend to be more connected to each other within the same group than to those outside. Therefore, the detection of these communities is a topic of great interest and importance in many applications and different algorithms including label propagation have been developed for such purpose. Speaker-listener label propagation algorithm
View details →DOI: 10.4236/sn.2013.23012Cited by 21 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Benjamin L. Rambo‐Martin, Jennifer G. Mulle, David J. Cutler et al. · 2017 · G3 Genes Genomes Genetics
One in five people with Down syndrome (DS) are born with an atrioventricular septal defect (AVSD), an incidence 2000 times higher than in the euploid population. The genetic loci that contribute to this risk are poorly understood. In this study, we tested two hypotheses: (1) individuals with DS carrying chromosome 21 copy number variants (CNVs) that interrupt exons may be protected from AVSD, because these CNVs return AVSD susceptibility loci back to disomy, and (2) individuals with DS carrying chromosome 21 genes spanned by microduplications are at greater risk for AVSD because these microdup
View details →DOI: 10.1534/g3.117.300366Cited by 21 Negative / Null Result ReportOpen accessMedicine
Duncan G.J. Green, Jinhee Kim, Stephen J. Kish et al. · 2021 · Journal of Psychiatry and Neuroscience
Background: Upregulation of the endocannabinoid enzyme fatty acid amide hydrolase (FAAH) has been linked to abnormal activity in frontoamygdalar circuits, a hallmark of posttraumatic stress disorder. We tested the hypothesis that FAAH…
View details →DOI: 10.1503/jpn.200010Cited by 21 Negative / Null Result ReportOpen accessNeuroscience
Adam Maxwell Sparks, Pat Barclay · 2015 · Letters on Evolutionary Behavioral Science
The effect of exposure to eye images on various behaviors has been explained as a response to an invalid cue of observation. This interpretation has been supported by an experiment showing that a short exposure to eye images increased…
View details →DOI: 10.5178/lebs.2015.35Cited by 21 Negative / Null Result Report
Pamela Laird, Roz Walker, Mary Lane et al. · 2019 · Respirology
ABSTRACT Background and objective Chronic lung disease is prevalent among Australian Aboriginal children. Chronic wet cough is an early marker of disease but often goes undetected. Currently, no studies have examined health practitioner…
View details →DOI: 10.1111/resp.13642Cited by 21 Negative / Null Result Report
Clarin Collins · 2014 · Education Policy Analysis Archives
This study examined the SAS Education Value-Added Assessment System (EVAAS®) in practice, as perceived and experienced by teachers in the Southwest School District (SSD). To evaluate teacher effectiveness, SSD is using SAS EVAAS® for…
View details →DOI: 10.14507/epaa.v22.1594Cited by 21 Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Yawen Chen · 2017 · Modern Economy
Based on the annual data of China from 2000 to 2014, this paper applies the dynamic panel model to study the relationship between inbound tourism and foreign direct investment (FDI). Compared with previous literatures, our analysis is not limited to the study of FDI in single tourism sectors such as hotels and restaurants, but takes general FDI into consideration. The empirical results show that the growth of inbound tourism can not only promote FDI flow into the tourism industries, but also increase the inflows of FDI to other sectors. In other words, the flourished inbound tourism may have s
View details →DOI: 10.4236/me.2017.81004Cited by 21 Negative / Null Result ReportOpen accessMedicine
Leah Wetherill, Dongbing Lai, Emma C. Johnson et al. · 2019 · Genes Brain & Behavior
Abstract Genetic influences on alcohol and drug dependence partially overlap, however, specific loci underlying this overlap remain unclear. We conducted a genome‐wide association study (GWAS) of a phenotype representing alcohol or illicit…
View details →DOI: 10.1111/gbb.12580Cited by 21 Negative / Null Result ReportOpen accessEnvironmental Science
Marina Reyne, Myles Nolan, Henry McGuiggan et al. · 2020 · Journal of Applied Ecology
Abstract Farmland ponds are a highly threatened freshwater habitat which has undergone dramatic losses during the last 200 years due to land drainage schemes and agricultural intensification. Agri‐environment schemes (AES) incentivize farmers to adopt farming methods to benefit biodiversity, yet there are a paucity of data evaluating the success of artificially created AES ponds as analogues of natural ponds in an attempt to recreate lost environments. We examined variation in environmental parameters and aquatic and terrestrial invertebrate communities between 38 natural ponds and 91 artifici
View details →DOI: 10.1111/1365-2664.13738Cited by 21 Negative / Null Result Report
Bo Christiansen · 2013 · Journal of Climate
Abstract The author investigates whether the increasing numbers of warm records and warm extremes in the extratropical Northern Hemisphere over the last decade are statistically significant. For the extremes, the focus is on summer mean…
View details →DOI: 10.1175/jcli-d-12-00814.1Cited by 21 Negative / Null Result ReportOpen accessMedicine
Wanzhu Tu, Samer Gawrieh, Srinivasan Dasarathy et al. · 2023 · Contemporary Clinical Trials Communications
Background: Mortality is high for severe alcohol-associated hepatitis (AH). Corticosteroids are the standard of care for patients without contraindications. Recent data showed that interleukin-1β receptor antagonist anakinra attenuated…
View details →DOI: 10.1016/j.conctc.2023.101074Cited by 21 Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Kamala Krishnaswamy · 2016 · Revista de Fomento Social
Worldwide non-communicable diseases (NCDs) occur due to multiple etiological factors impacting development and economic progress. Developing countries have dual burden of diseases viz., under and over nutrition, which are critical public…
View details →DOI: 10.16943/ptinsa/2016/48881Cited by 21 Negative / Null Result ReportMedicine
Valerie A. Smith, Joan E. Cunningham, Eric J. Lentsch · 2012 · Otolaryngology
OBJECTIVE: Determine if completion lymph node dissection (CLND) is associated with improved survival in sentinel lymph node (SLN)-positive cutaneous melanoma of the head and neck (CMHN) patients. STUDY DESIGN: Retrospective analysis of…
View details →DOI: 10.1177/0194599811432672Cited by 21 Negative / Null Result ReportOpen accessMedicine
Alexander Filatenkov, Jeanette Baker, Antonia Müller et al. · 2014 · Radiation Research
The goal of this study was to determine whether a combination of local tumor irradiation and autologous T-cell transplantation can effectively treat metastatic 4T1 breast cancer in mice. BALB/c mice were injected subcutaneously with…
View details →DOI: 10.1667/rr13471.1Cited by 21 Negative / Null Result ReportOpen accessMedicine
Hidehiko Okazawa, Tetsuya Tsujikawa, Yoshifumi Higashino et al. · 2019 · EJNMMI Research
Accurate attenuation correction (AC) is one of the most important issues to be addressed in quantitative brain PET/MRI imaging. Atlas-based MRI AC (AB-MRAC), one of the representative MRAC methods, has been used to estimate the skull attenuation in brain scans. The zero echo time (ZTE) pulse sequence is also expected to provide a better MRAC estimation in brain PET scans. The difference in quantitative measurements of cerebral blood flow (CBF) using H215O-PET/MRI was compared between the two MRAC methods, AB and ZTE. Twelve patients with cerebrovascular disease (4 males, 43.2 ± 11.7 years) und
View details →DOI: 10.1186/s13550-019-0494-9Cited by 21 Negative / Null Result ReportOpen accessMedicine
Eisaku Miyauchi, Tatsuo Matsuda, Kazuma Kiyotani et al. · 2018 · Cancer Science
Recent clinical trials of non-small cell lung cancer with immune checkpoint inhibitors revealed that patients with epidermal growth factor receptor (EGFR) mutations had more unfavorable outcomes compared with those with wild-type EGFR.…
View details →DOI: 10.1111/cas.13919Cited by 21 Negative / Null Result ReportOpen accessMedicine
Junyi Chen, Jiao Li, Chuanliang Xu et al. · 2012 · BMC Cancer
BACKGROUND: Gamma-synuclein (SNCG) has previously been demonstrated to be significantly correlated with metastatic malignancies; however, in-depth investigation of SNCG in prostate cancer is still lacking. In the present study, we evaluated the role of SNCG in prostate cancer progression and explored the underlying mechanisms. METHODS: First, alteration of SNCG expression in LNCaP cell line to test the ability of SNCG on cellular properties in vitro and vivo whenever exposing with androgen or not. Subsequently, the Dual-luciferase reporter assays were performed to evaluate whether the role of
View details →DOI: 10.1186/1471-2407-12-593Cited by 21 Negative / Null Result ReportMedicine
Sebastian Richards-Taylor, Charles Tilley, Eleanor Jaynes et al. · 2017 · Pancreas
OBJECTIVE: Pancreatic neuroendocrine tumors (NETs) (pNETs) have a varied prognosis according to their grade. The European Neuroendocrine Tumor Society grading system uses assessment of the proliferation index via Ki-67 immunohistochemistry…
View details →DOI: 10.1097/mpa.0000000000000933Cited by 21 Negative / Null Result ReportOpen accessMedicine
Herbert S. B. Baraf, Puja Khanna, Alan Kivitz et al. · 2023 · Lara D. Veeken
OBJECTIVES: Serum urate (SU) lowering with PEGylated uricases in gout can reduce flares and tophi. However, treatment-emergent anti-drug antibodies adversely affect safety and efficacy and the currently approved PEGylated uricase…
View details →DOI: 10.1093/rheumatology/kead333Cited by 21 Negative / Null Result ReportOpen accessSocial Sciences
Dafina Petrova, Edward T. Cokely, Agata Sobków et al. · 2022 · Risk Analysis
We introduce a brief instrument specifically validated for measuring positive and negative feelings about risks-the Berlin Emotional Responses to Risk Instrument (BERRI). Based on seven studies involving diverse adults from three countries…
View details →DOI: 10.1111/risa.13946Cited by 21 Negative / Null Result ReportArts and Humanities
Loren Kajikawa · 2020 · twentieth-century music
Abstract The last two decades have witnessed a dramatic rise in dissertations, theses, and other academic publications exploring hip-hop music, while college courses on hip-hop history have become commonplace. The growing prominence of…
View details →DOI: 10.1017/s1478572220000262Cited by 21 Negative / Null Result Report
S. L. Matheson, A. M. Shepherd, V. J. Carr · 2014 · Psychological Medicine
Background. True findings about schizophrenia remain elusive; many findings are not replicated and conflicting results are common. Well-conducted systematic reviews have the ability to make robust, generalizable conclusions, with good…
View details →DOI: 10.1017/s0033291714000166Cited by 21 Negative / Null Result Report
Evrim Bostankolu, Hilal Ayoglu, Serhan Yurtlu et al. · 2012 · The Kaohsiung Journal of Medical Sciences
Abstract Ischemia reperfusion injury causes the release of free oxygen radicals. Free oxygen radicals initiate the production of toxic metabolites, such as malondialdehyde (MDA), through the lipid peroxidation of cellular membranes.…
View details →DOI: 10.1016/j.kjms.2012.08.013Cited by 21 Negative / Null Result Report
Qing Miao · 2018 · Risk Analysis
Abstract There has been a growing interest in understanding whether and how people adapt to extreme weather events in a changing climate. This article presents one of the first empirical analyses of adaptation to flooding on a global…
View details →DOI: 10.1111/risa.13245Cited by 21 Replication FailureMedicine
Anthony T.�C. Chan, Edwin P. Hui, Roger K.C. Ngan et al. · 2017 · Journal of Clinical Oncology
6002 Background: The benefit of adjuvant CT in NPC is unclear. Post-RT EBV DNA predicts poor survival and may be a biomarker of subclinical residual disease. We conducted a biomarker driven RCT using post-RT EBV DNA to select high risk NPC…
View details →DOI: 10.1200/jco.2017.35.15_suppl.6002Cited by 21 