Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Manuel A. Silva, Anderson Veronese, Anna Luiza Belli et al. · 2021 · Journal of Dairy Science
kg) than cows diagnosed with a clinical disease that had an AMD alert. Adding AMD-generated health alerts to the health screening of postpartum cows in a herd with an existing screening program did not improve survival, milk yield, or…
View details →DOI: 10.3168/jds.2020-18562Cited by 14 Negative / Null Result ReportOpen accessEngineering
Gábor Szabó, András Ágoston, Gábor Csató et al. · 2021 · Sensors
As demonstrated by earlier studies, pre-hospital triage with trans-telephonic electrocardiogram (TTECG) and direct referral for catheter therapy shows great value in the management of out-of-hospital chest pain emergencies. It does not only improve in-hospital mortality in ST-segment elevation myocardial infarction, but it has also been identified as an independent predictor of higher in-hospital survival rate. Since TTECG-facilitated triage shortens both transport time and percutaneous coronary intervention (PCI)-related procedural time intervals, it was hypothesized that even high-risk patie
View details →DOI: 10.3390/s21030969Cited by 14 Negative / Null Result Report
Goran Rondovic, Dragan Djordjevic, Ivo Udovicic et al. · 2022 · Biomedicines
Complex immune response to infection has been highlighted, more than ever, during the COVID-19 pandemic. This review explores the immunomodulatory treatment of moderate-to-severe forms of this viral sepsis in the context of specific…
View details →DOI: 10.3390/biomedicines10102620Cited by 14 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Wil Biddle, David G. Schwark, Margaret A. Schmitt et al. · 2022 · Frontiers in Chemistry
The expansion of the genetic code beyond a single type of noncanonical amino acid (ncAA) is hindered by inefficient machinery for reassigning the meaning of sense codons. A major obstacle to using directed evolution to improve the efficiency of sense codon reassignment is that fractional sense codon reassignments lead to heterogeneous mixtures of full-length proteins with either a ncAA or a natural amino acid incorporated in response to the targeted codon. In stop codon suppression systems, missed incorporations lead to truncated proteins; improvements in activity may be inferred from increase
View details →DOI: 10.3389/fchem.2022.815788Cited by 14 Negative / Null Result ReportOpen accessMedicine
Jan Walter Benjamins, Ming Wai Yeung, Teemu Maaniitty et al. · 2021 · International Journal of Cardiology
BACKGROUND: Standard computed tomography angiography (CTA) outputs a myriad of interrelated variables in the evaluation of suspected coronary artery disease (CAD). But an important proportion of obstructive lesions does not cause significant myocardial ischemia. Nowadays, machine learning (ML) allows integration of numerous variables through complex interdependencies that optimize classification and prediction at the individual level. We evaluated ML performance in integrating CTA and clinical variables to identify patients that demonstrate myocardial ischemia through PET and those who ultimat
View details →DOI: 10.1016/j.ijcard.2021.04.009Cited by 13 Negative / Null Result ReportOpen accessPhysics and Astronomy
Sara Kurkowska, Julia Brosch-Lenz, Yuni K. Dewaraja et al. · 2025 · Journal of Nuclear Medicine
Individualized radiopharmaceutical therapies guided by patient-specific absorbed dose (AD) assessments using nuclear medicine imaging have the potential to improve both efficacy and safety. Understanding sources of variability in AD calculations is critical for standardization. The Society of Nuclear Medicine and Molecular Imaging Dosimetry Task Force launched the 177Lu Dosimetry Challenge to evaluate variability across steps within the dosimetry workflow. This work aimed to assess the variability in ADs due to different fitting and integration methods. Methods: Anonymized datasets from 2 pati
View details →DOI: 10.2967/jnumed.124.268612Cited by 13 Negative / Null Result ReportOpen accessNeuroscience
Maliha Ashraf, Alexandre Chapiro, Rafał Mantiuk · 2025 · Nature Communications
As large engineering efforts go towards improving the resolution of mobile, augmented reality (AR), and virtual reality (VR) displays, it is important to know the maximum resolution at which further improvements bring no noticeable benefit. This limit is often referred to as the retinal resolution, although the limiting factor may not necessarily be attributed to the retina. To determine the ultimate resolution at which an image appears sharp to our eyes with no perceivable blur, we created an experimental setup with a sliding display, which allows for continuous control of the resolution. The
View details →DOI: 10.1038/s41467-025-64679-2Cited by 13 Negative / Null Result ReportOpen accessMedicine
Jiangfeng Li, Zheng Li, 韩丽黎 et al. · 2026 · Signal Transduction and Targeted Therapy
Dysregulated glucose metabolism in diabetic wound macrophages impairs polarization toward the reparative M2 phenotype, leading to compromised innate immunity, chronic inflammation, and delayed wound healing. However, effective strategies…
View details →DOI: 10.1038/s41392-026-02647-yCited by 13 Negative / Null Result ReportOpen accessPhysics and Astronomy
Chuneeta D. Nunhokee, Donald M. Null, Cathryn M. Trott et al. · 2025 · The Astrophysical Journal
Abstract This paper presents the spherically averaged 21 cm power spectrum derived from Epoch of Reionization (EoR) observations conducted with the Murchison Widefield Array (MWA). The analysis uses EoR0-field data, centered at (R.A. = 0 h , decl. = −27 ∘ ), collected between 2013 and 2023. Building on the improved methodology described in C. M. Trott et al. (2024), we incorporate additional data quality control techniques introduced in C. D. Nunhokee (2020). We report the lowest-power-level limits on the EoR power spectrum at redshifts z = 6.5, z = 6.8, and z = 7.0. These power levels, measur
View details →DOI: 10.3847/1538-4357/adda45Cited by 13 Negative / Null Result ReportOpen accessEnvironmental Science
Barbara Smith, Dan Carpenter, J. M. Holland et al. · 2023 · Journal of Applied Ecology
Abstract Lowland heath is a priority habitat for conservation, nowadays largely managed for biodiversity. Historically, prescribed burning has been the principal management tool, but there are increasing calls to substitute burning with cutting to improve biodiversity outcomes. However, poor understanding of potential impacts compromises decision making. Our study was carried out in the New Forest National Park, the largest area of lowland heath in Europe. Using a multi‐trophic approach, we compared the ecological impact of prescribed burning with two types of vegetation cutting (swiping and b
View details →DOI: 10.1111/1365-2664.14471Cited by 13 Negative / Null Result Report
Elysia Larson, Godfrey M Mbaruku, Jessica Cohen et al. · 2019 · International Journal for Quality in Health Care
Abstract Objective To test the success of a maternal healthcare quality improvement intervention in actually improving quality. Design Cluster-randomized controlled study with implementation evaluation; we randomized 12 primary care…
View details →DOI: 10.1093/intqhc/mzz126Cited by 13 Negative / Null Result ReportOpen accessMedicine
Ryota Nishio, Tomotaka Dohi, Miho Yokoyama et al. · 2025 · JMIR mhealth and uhealth
Background: Cardiac rehabilitation (CR) is effective in preventing cardiovascular diseases; however, participation in CR programs remains limited due to the associated challenges. The integration of wearable devices and real-time monitoring offers a potential solution to enhance adherence to remote CR programs and their outcomes. Objective: This study aimed to evaluate the efficacy of a remote CR program using wearable devices and real-time monitoring with or without online coaching (OLC) in improving exercise capacity in patients with coronary artery disease (CAD). Methods: We enrolled 50 pat
View details →DOI: 10.2196/63797Cited by 13 Negative / Null Result Report
Henry W. Caplan, Karthik S. Prabhakara, Naama E. Toledano Furman et al. · 2021 · PLOS ONE
Traumatic brain injury (TBI) causes both physical disruption of the blood brain barrier (BBB) and altered immune responses that can lead to significant secondary brain injury and chronic inflammation within the central nervous system…
View details →DOI: 10.1371/journal.pone.0251601Cited by 13 Negative / Null Result Report
Qihan Ma, Jianbo Wang, Ming Xiong et al. · 2023 · Remote Sensing
The lockdowns from the coronavirus disease of 2019 (COVID-19) have led to a reduction in anthropogenic activities and have hence reduced primary air pollutant emissions, which were reported to have helped air quality improvements. However,…
View details →DOI: 10.3390/rs15051295Cited by 13 Negative / Null Result ReportOpen accessMedicine
Daniel I. McIsaac, Susan M. Lee, Dean Fergusson et al. · 2025 · JAMA Surgery
Importance: Explanatory trials suggest that prehabilitation has efficacy in improving surgical outcomes. The effectiveness of offering home-based prehabilitation across multiple centers and for older adults with frailty remains unknown. Objective: To evaluate the effectiveness of offering coach-supported, home-based prehabilitation to older surgical patients with frailty. Design, Setting, and Participants: This study is a pragmatic, parallel-arm, multicenter randomized clinical trial with embedded qualitative assessment. Clinicians and assessors were fully blinded; participants were partially
View details →DOI: 10.1001/jamasurg.2025.5288Cited by 13 Negative / Null Result Report
Mohammad Nourani, Qian Long Kweh, Wen-Min Lu et al. · 2022 · Financial Innovation
Abstract This study examines the efficiency of investment trust companies (ITCs) from 2011 to 2020 using a meta-frontier two-stage network data envelopment analysis (DEA) based on the directional distance function (DDF). We improved the…
View details →DOI: 10.1186/s40854-022-00382-1Cited by 13 Negative / Null Result ReportMedicine
Jing Luo, Zheng Dong, Hui Xie et al. · 2022 · Liver International
BACKGROUND & AIMS: Management of elderly patients with hepatocellular carcinoma (HCC) has become a major concern. Some data suggest that cryoablation improves the outcomes of elderly patients with HCC, but its efficacy and safety remain…
View details →DOI: 10.1111/liv.15169Cited by 13 Negative / Null Result Report
S.F. Hall, R. Griffiths · 2016 · Current Oncology
Background: For oncologists and for patients, no site-specific clinical trial evidence has emerged for the use of concurrent chemotherapy with radiotherapy (ccrt) over radiotherapy (rt) alone for cancer of the hypopharynx (hpc) or for…
View details →DOI: 10.3747/co.23.3085Cited by 13 Negative / Null Result ReportOpen accessComputer Science
Rabab Ali Abumalloh, Mehrbakhsh Nilashi, Osama Halabi et al. · 2024 · Journal of Innovation & Knowledge
Recommendation agents (RAs) have proven to be effective decision-making tools for customers, as they can boost trust and loyalty when customers shop online. They can analyse large amounts of data using machine learning algorithms and…
View details →DOI: 10.1016/j.jik.2024.100569Cited by 13 Negative / Null Result ReportOpen accessMaterials Science
Malek Msheik, Sylvain Rodat, Stéphane Abanades · 2024 · Journal of Analytical and Applied Pyrolysis
Solar methane pyrolysis in different molten media and reactor configurations was experimented to improve hydrogen production . Pure Sn, Ni 0.18 Sn 0.82 , Cu 0.45 Bi 0.55 , and KCl melts were compared at three different temperatures…
View details →DOI: 10.1016/j.jaap.2024.106756Cited by 13 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Jing Mai, Ying Ning, Zhonglong Lin et al. · 2025 · Industrial Crops and Products
Many bacteria such as Bacillus , Pseudomonas , and Lactobacillus are widely present in flue-cured tobacco leaves during the aging process, indicating they play important roles in improving tobacco quality. In this study, we aimed to screen…
View details →DOI: 10.1016/j.indcrop.2025.121580Cited by 12 Negative / Null Result Report
Gabriela Yamazaki de Campos, Raquel Amorim Oliveira, Patrícia Kellen Martins Oliveira-Brito et al. · 2020 · PeerJ
Background The macrophage lineage is characterized by plasticity due to the acquisition of distinct functional phenotypes, and two major subsets are evaluated; classical M1 activation (strong microbicidal activity) and alternative M2…
View details →DOI: 10.7717/peerj.10295Cited by 12 Negative / Null Result ReportOpen accessMaterials Science
Luis E. Castro-Anaya, Eduardo Marese, Jaime A. Lozano et al. · 2025 · Journal of Chemical Information and Modeling
High Resolution Image Download MS PowerPoint Slide Traditionally, designing novel materials involves exploring new compositions guided by insights from previous work, relying on a trial-and-error approach, where continuous synthesis and characterization proceed until the properties meet the improvements. This method is inefficient due to the challenges of exploring vast chemical spaces. In this study, a machine-learning-based methodology is developed to assist the design from available data in the literature, allowing us to test in silico more than 1.2 million compositions. Two databases with
View details →DOI: 10.1021/acs.jcim.4c01944Cited by 12 Negative / Null Result ReportOpen accessComputer Science
Husna Husna, Khalid Abdullah Al Muzaini, Maryam Rashid Saleh Al Tamimi et al. · 2026 · Ar-Rayyan Journal of Islamic Education
The increasing availability of educational data has opened new opportunities for improving instructional decision-making through learning analytics. However, its application in Islamic Religious Education (IRE) remains limited, particularly in predicting students’ academic achievement and learning behavior. This study aims to develop a learning analytics model capable of identifying learning patterns and predicting students’ performance in IRE. A quantitative research design employing Educational Data Mining (EDM) techniques was conducted using learning management system (LMS) data from 512 se
View details →DOI: 10.67899/ar.v3i1.225Cited by 12 Negative / Null Result Report
Yumeng Zhang, Premsai Kumar, Jacob J. Adashek et al. · 2022 · Cells
Modulating the cyclooxygenase 2 (COX-2) pathway has improved responses to immune checkpoint inhibitors (ICIs) in certain solid tumors, such as melanoma. Little is known about COX-2 inhibition in response to ICIs in metastatic renal cell…
View details →DOI: 10.3390/cells11162505Cited by 12 Negative / Null Result ReportOpen accessSocial Sciences
Laura Macchi, Francesco Poli, Laura Caravona et al. · 2019 · Europe’s Journal of Psychology
The previous research attempts to reduce the influence of the belief bias on deductive thinking have often been unsuccessful and, when they succeeded, they failed to replicate. In this paper, we propose a new way to see an old problem. Instead of considering the analytical abilities of the respondent, we focus on the communicative characteristics of the experimental task. By changing the pragmatics into play through a subtle manipulation of the instruction of the syllogism problem, we obtained a strong improvement in the accuracy of the performance in both untrained and trained in logic respon
View details →DOI: 10.5964/ejop.v15i3.1794Cited by 12 Negative / Null Result ReportOpen accessMedicine
Helen L. Reeves, John Reicher, Georgia Priona et al. · 2022 · Frontline Gastroenterology
Objective: Hepatocellular carcinoma (HCC) deaths are rising alarmingly. Many patients are unsuitable for available therapies. Poor response rates further hamper outcomes for those that are. Selective internal radiation therapy (SIRT) offers hope, although which patients benefit over standard approaches remains unclear. Design/method: As a quality/service improvement, we audited consecutive patients treated with SIRT (2015-2020) by the Newcastle upon Tyne Hospitals National Health Service Foundation Trust HCC multidisciplinary team. Indications, Barcelona clinic liver cancer (BCLC) stage, treat
View details →DOI: 10.1136/flgastro-2022-102137Cited by 12 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Marlee R. Labroo, Jessica Rutkoski · 2022 · BMC Genomics
BACKGROUND: Recurrent selection is a foundational breeding method for quantitative trait improvement. It typically features rapid breeding cycles that can lead to high rates of genetic gain. Usually, generations are discrete in recurrent selection, which means that breeding candidates are evaluated and considered for selection for only one cycle. Alternately, generations can overlap, with breeding candidates considered for selection as parents for multiple cycles. With recurrent genomic selection but not phenotypic selection, candidates can be re-evaluated by using genomic estimated breeding v
View details →DOI: 10.1186/s12864-022-08929-3Cited by 12 Negative / Null Result ReportOpen accessMedicine
Brian Hitsman, George D. Papandonatos, Jackie K. Gollan et al. · 2023 · Addiction
BACKGROUND AND AIMS: Treatment of depression-related psychological factors related to smoking behavior may improve rates of cessation among adults with major depressive disorder (MDD). This study measured the efficacy and safety of 12…
View details →DOI: 10.1111/add.16209Cited by 12 Negative / Null Result ReportOpen accessMaterials Science
L L Sun, Yisa Zhao, Xiyu Caomeng et al. · 2026 · ChemistryOpen
Traditional blending electrospinning has a series of issues during implementation, and the corresponding monolithic nanofibers can always be updated through the intentional design of core-sheath nanostructures. In this study, a modified coaxial electrospinning approach was employed to refine the electrospinning process by eliminating abnormal phenomena, while simultaneously imparting core-sheath nanostructures and improved transdermal finasteride (FIN) delivery performance. Using an electrospinnable ethylcellulose (EC) solution containing FIN as the core fluid and an unspinnable polyvinylpyrro
View details →DOI: 10.1002/open.202500564Cited by 12 