Adding Cyclooxygenase Inhibitors to Immune Checkpoint Inhibitors Did Not Improve Outcomes in Metastatic Renal Cell Carcinoma
Yumeng Zhang; Premsai Kumar; Jacob J. Adashek; William P. Skelton; Jiannong Li; Aram Vosoughi; Jad Chahoud; Brandon J. Manley · 2022 · Cells
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Modulating the cyclooxygenase 2 (COX-2) pathway has improved responses to immune checkpoint inhibitors (ICIs) in certain solid tumors, such as melanoma. Little is known about COX-2 inhibition in response to ICIs in metastatic renal cell…
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Metadata source: Crossref · DOI 10.3390/cells11162505