A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
750 results in Failed Experiment Report · page 10 of 25
Celik F, Gungor IH, Uslug M et al. · 2026 · Parasitology research
Cystic echinococcosis (CE) is a chronic zoonotic disease caused by Echinococcus granulosus, primarily affecting the liver and lungs of livestock but also capable of inducing systemic alterations through oxidative stress and metabolic…
Kuruppu J, Purdy JB, Pauls C et al. · 2026 · Open forum infectious diseases
Background Some people with HIV (PWH) have a poor immunologic response to antiretroviral therapy (ART). Such immunologic nonresponders are at increased risk for HIV and non-HIV related complications. Immune exhaustion may contribute to…
G. Hathaway, L. L. Williams · 2021 · arXiv
We report test results searching for an effect of electrostatic charge on weight. For conducting test objects of mass of order 1 kilogram, we found no effect on weight, for potentials ranging from 10 V to 200 kV, corresponding to charge states ranging from $10^{-9}$ to over $10^{-5}$ coulombs, and for both polarities, to within a measurement precision of 2 grams. While such a result may not be unexpected, this is the first unipolar, high-voltage, meter-scale, static test for electro-gravitic effects reported in the literature. Our investigation was motivated by the search for possible coupling
Al-Quraan LT, Al-Trad B, Alomari G et al. · 2026 · Current molecular medicine
Introduction This study aimed to address the effects of 1,8-cineole on diabetic muscular atrophy in streptozotocin (STZ)-induced diabetic rats. Materials and methods Adult male rats were divided into three groups (n = 15): nondiabetic…
Celik M, Polat ME, Ceviz K et al. · 2026 · World journal of urology
Purpose Vasculogenic erectile dysfunction (ED) is associated with endothelial dysfunction and oxidative stress. This study evaluated the clinical efficacy of radial-type low-intensity extracorporeal shockwave therapy (Li-ESWT) and its…
Van Overmeiren T, de Alaiza Ortega SG, Calle S et al. · 2026 · Progress in cardiovascular diseases
Background Mavacamten is a cardiac myosin inhibitor used for patients with obstructive hypertrophic cardiomyopathy (oHCM). The efficacy and safety of this negative inotropic agent in oHCM and concomitant left bundle branch block (LBBB)…
Hernandez Lopez A, Post R, Chung J et al. · 2026 · The Permanente journal
Background Postpartum hemorrhage remains a leading cause of severe maternal morbidity and mortality. The association between mild thrombocytopenia and postpartum blood loss or red blood cell transfusion has not been well studied. Objective…
Doumbia M, Yoroba F, Koné B et al. · 2026 · Preprint
Abstract This study evaluates how different physical parameterization schemes affect precipitation simulation in the Bandama watershed (Côte d’Ivoire) using the RegCM5 regional climate model. Thirteen configurations were developed,…
Cabrera GJ, Farías P, Sáez CG · 2026 · Journal of voice : official journal of the Voice Foundation
Introduction Parkinson's disease (PD) is frequently associated with voice and speech impairments that negatively affect communication and quality of life. Although several studies have identified vocal variables with potential clinical…
Edwards MA, Petty SB, Chawla K et al. · 2026 · American journal of surgery
Objectives This retrospective cohort of patients undergoing surgery from 2019 to 2023 evaluated the association between individual-level social drivers of health (SDoH) and postoperative outcomes (length of stay, 30-day mortality, 30-day…
Bhat YA, Mocavini I, O’Donnell E et al. · 2026 · Preprint
The Bre1 ubiquitin conjugating enzyme catalyzes the monoubiquitylation of histone H2B-K120/K123 at promoter proximal nucleosomes, contributing to transcriptional regulation. These same nucleosomes are targeted by the yeast SWR1C chromatin…
Lin S, Wei H, Guo C et al. · 2026 · Microbial pathogenesis
Colletotrichum graminicola, the causal agent of maize anthracnose, is responsible for substantial global crop losses. While the fluffy family proteins (FlbA-FlbE, FluG) are known as key upstream activators of asexual development in…
Holden A, Burns P, Devenny A et al. · 2026 · Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
Background Improved survival in cystic fibrosis (CF) has shifted clinical focus toward late complications, including altered body composition, bone health and cardiopulmonary fitness. The effects of Elexacaftor/Tezacaftor/Ivacaftor (ETI)…
Bhargavi R, Amirtharaj KSV, Athithan S et al. · 2026 · Preprint
Abstract In aquaculture systems, salinity has a significant impact on physiological function, water quality, and total productivity. This study used a periphyton-based system supported by split bamboo substrate to evaluate the survival and…
Atay A, Samiloglu DCA, Sismanoglu S et al. · 2026 · Odontology
The increasing use of digitally fabricated resin-based materials for definitive dental restorations has raised concerns regarding their biological performance and biocompatibility. This in vitro study evaluated the biocompatibility and…
Jacob R, Walton K, Buchholz AC et al. · 2026 · Appetite
Children's eating behaviours are important determinants of childhood obesity; however, few studies have examined whether early childhood obesity prevention interventions influence these behaviours. This study investigated the impact of a…
Matthew Boyea, null null, null null et al. · 2022 · John Heinrichs Scholarly & Creative Activities Day
Modern manufacturing processes increasingly demand machine driven solutions When developing robot applications in industry, programmers must be able to safely write code which is reusable, expandable, and well documented This case study…
Williams K, Craswell A, Tsao H et al. · 2026 · Emergency medicine Australasia : EMA
Objective Australia's ageing population resulted in increasing Emergency Department (ED) presentations among older adults, particularly frail and those at risk of adverse outcomes. Delirium contributes significantly to morbidity in this…
Seojoon Park, Paul Adams, null null et al. · 2020 · John Heinrichs Scholarly & Creative Activities Day
Every person would have thought of this idea of launching aballoon high up in the sky in their youth, and that is exactlywhat we did. We filled a large elastic balloon filled withhelium and flew it high up into the sky until it popped…
Sekmen S, Hursoy N, Panc K et al. · 2026 · Clinical imaging
Aim This study aims to explore the correlation between background parenchymal enhancement (BPE) observed in breast magnetic resonance imaging (MRI) and the presence of breast cancer. Materials and methods A total of 761 patients (326…
Ariizumi T, Oike N, Murayama Y et al. · 2026 · Discover oncology
Background Giant cell tumor of bone (GCTB) is a locally aggressive tumor that rarely metastasizes, although a small subset undergoes malignant transformation. H3F3A driver mutations have been recognized as characteristic molecular features…
Omidifar N, Najafi E, Nasiri K et al. · 2025 · BMC pregnancy and childbirth
BACKGROUND: Despite numerous studies on the impact of stress on post-in vitro fertilization (IVF) clinical outcomes are contradictory and researchers recommend the need for further studies. Therefore, the purpose of the present study was…
Hinkelmann MA, Schibler D, Frei F et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
INTRODUCTION: Midshaft clavicle fractures are commonly treated with plate fixation; however, the selected plate working length varies widely. Biomechanical principles suggest potential effects on fracture healing, but clinical evidence…
Kawase S, Sato N, Yoshida M et al. · 2026 · Preprint
Abstract Body size is a critical trait influencing reproductive success through mate competition, female choice, and parental care ability. In fish species with alternative reproductive tactics, large males typically adopt dominant…
Bagińska M, Morawska-Tota M, Pałka T et al. · 2026 · Journal of clinical medicine
Background/Objectives : Bone tissue undergoes continuous remodelling processes that are closely controlled by mechanical stimuli and metabolic as well as inflammatory factors. Although the beneficial effects of regular physical activity on…
Bayram Y, Yildiz H, Ulger G et al. · 2026 · Journal of ovarian research
Background This study METHODS: A total of 662 patients treated at the Assisted Reproductive Techniques Unit of Mersin University Faculty of Medicine between 2016 and 2024 (Group 3: n=245; Group 4: n=417) were retrospectively analyzed.…
Wu L, Sun Q, Wang X et al. · 2026 · Plants (Basel, Switzerland)
Heavy metals in soil can be translocated to floral rewards via specific physiological pathways, potentially altering pollinator behavior and reducing plant reproductive fitness. However, the comparative effects of different heavy metals on…
Sugase T, Kanemura T, Matsuura N et al. · 2026 · Annals of surgical oncology
Background Adjuvant nivolumab has become a standard treatment after curative resection for locally advanced esophageal cancer; however, postoperative recurrence remains common. The efficacy of immune checkpoint inhibitor (ICI)-based…
Nishimura T, Kodama T, Chiba K et al. · 2026 · Physical chemistry chemical physics : PCCP
To identify factors that enhance thermochemical redox reaction efficiency, we have investigated the thermochemical properties of transition-metal-doped cerium oxide. This study examines thermodynamic parameters using vibrational entropy…
Sung K, Park M, Kweon O et al. · 2026 · Food Microbiology.
Campylobacter jejuni is a foodborne pathogen with limited ability to thrive at low temperatures. This study investigated the survival and proteomic responses of C. jejuni NCTC 11168 during prolonged storage at 4 °C, with specific focus on…