Negative / Null Result ReportOpen accessHealth Professions
Isabelle Scholl, Levente Kriston, Jörg Dirmaier et al. · 2012 · Health Expectations
BACKGROUND: While there has been a clear move towards shared decision-making (SDM) in the last few years, the measurement of SDM-related constructs remains challenging. There has been a call for further psychometric testing of known…
View details →Negative / Null Result ReportMedicine
Margarida Corominas-Roso, Josep Antoni Ramos‐Quiroga, Marta Ribasés et al. · 2013 · The International Journal of Neuropsychopharmacology
It has been hypothesized that brain-derived neurotrophic factor (BDNF) is involved in the pathogenesis of attention-deficit hyperactivity disorder (ADHD), although experimental data regarding the contribution of BDNF gene polymorphisms to…
View details →Negative / Null Result ReportOpen accessMedicine
Bernard F. Fuemmeler, Chongming Yang, Phil Costanzo et al. · 2012 · Health Psychology
OBJECTIVE: Parenting styles such as authoritarian, disengaged, or permissive are thought to be associated with greater adolescent obesity risk than an authoritative style. This study assessed the relationship between parenting styles and…
View details →Negative / Null Result ReportOpen accessMedicine
Daqing Hong, Jeong Jin Min, Jeongwon Kim et al. · 2010 · Anaesthesia and Intensive Care
In several recent clinical trials on cardiac surgery patients, remote ischaemic preconditioning (RIPC) showed a powerful myocardial protective effect. However the effect of RIPC has not been studied in patients undergoing off-pump coronary…
View details →Negative / Null Result ReportPsychology
Hussam Jefee-Bahloul, Moustafa K. Moustafa, Fatma M. Shebl et al. · 2014 · Telemedicine Journal and e-Health
BACKGROUND: Given the scarcity of mental health resources available for refugees in areas of conflict, it is imperative to investigate interventions that would be accepted by the refugees. MATERIALS AND METHODS: In this study we surveyed…
View details →Negative / Null Result ReportOpen accessMedicine
Michael Weller, Burt Nabors, Thierry Gorlia et al. · 2016 · Oncotarget
// Michael Weller 1 , Louis Burt Nabors 2 , Thierry Gorlia 3 , Henning Leske 4 , Elisabeth Rushing 4 , Pierre Bady 5, 6, 7 , Christine Hicking 8 , James Perry 9 , Yong-Kil Hong 10 , Patrick Roth 1 , Wolfgang Wick 11, 12 , Simon L. Goodman 8 , Monika E. Hegi 7 , Martin Picard 8 , Holger Moch 13 , Josef Straub 8 , Roger Stupp 14 1 Department of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland 2 University of Alabama at Birmingham, Birmingham, AL, USA 3 EORTC Data Centre, Brussels, Belgium 4 Institute of Neuropathology, University Hospital Zurich, Zurich, Switze
View details →Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Ngô Thái Hưng · 2019 · Journal of Economics Finance and Administrative Science
Purpose This paper aims to study the daily returns and volatility spillover effects in common stock prices between China and four countries in Southeast Asia (Vietnam, Thailand, Singapore and Malaysia). Design/methodology/approach The analysis uses a vector autoregression with a bivariate GARCH-BEKK model to capture return linkage and volatility transmission spanning the period including the pre- and post-2008 Global Financial Crisis. Findings The main empirical result is that the volatility of the Chinese market has had a significant impact on the other markets in the data sample. For the sto
View details →Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Sebastian Karcher, David A. Steinberg · 2012 · International Studies Quarterly
Why do countries open their economies to global capital markets? A number of recent articles have found that two types of factors encourage politicians to liberalize their capital accounts: strong macroeconomic fundamentals and political…
View details →Negative / Null Result ReportMedicine
Richard H. White, Ann Brunson, Patrick S. Romano et al. · 2016 · Circulation
BACKGROUND: Evidence that vena cava filters (VCFs) are beneficial is limited. METHODS AND RESULTS: We retrospectively analyzed all noncancer patients admitted to nonfederal California hospitals for acute venous thromboembolism from 2005 to…
View details →Negative / Null Result ReportOpen accessMedicine
John‐Stuart Brittain, Hayriye Cagnan, Arpan R. Mehta et al. · 2015 · Journal of Neuroscience
Parkinson's disease (PD) and essential tremor (ET) are the two most common movement disorders. Both have been associated with similar patterns of network activation leading to the suggestion that they may result from similar network dysfunction, specifically involving the cerebellum. Here, we demonstrate that parkinsonian tremors and ETs result from distinct patterns of interactions between neural oscillators. These patterns are reflected in the tremors' derived frequency tolerance, a novel measure readily attainable from bedside accelerometry. Frequency tolerance characterizes the temporal ev
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Shane Coffield, Casey Graff, Yang Chen et al. · 2019 · International Journal of Wildland Fire
Fires in boreal forests of Alaska are changing, threatening human health and ecosystems. Given expected increases in fire activity with climate warming, insight into the controls on fire size from the time of ignition is necessary. Such…
View details →Negative / Null Result ReportMedicine
Helena Brodská, J Valenta, Květa Pelinková et al. · 2017 · Clinical Chemistry and Laboratory Medicine (CCLM)
BACKGROUND: Inflammatory biomarkers may aid to distinguish between systemic inflammatory response syndrome (SIRS) vs. sepsis. We tested the hypotheses that (1) presepsin, a novel biomarker, can distinguish between SIRS and sepsis, and (2)…
View details →Negative / Null Result ReportOpen accessMedicine
Howard R. Weeks, Scott C. Tadler, Kelly W. Smith et al. · 2013 · PLoS ONE
BACKGROUND: Many patients have serious depression that is nonresponsive to medications, but refuse electroconvulsive therapy (ECT). Early research suggested that isoflurane anesthesia may be an effective alternative to ECT. Subsequent studies altered drug, dose or number of treatments, and failed to replicate this success, halting research on isoflurane's antidepressant effects for a decade. Our aim was to re-examine whether isoflurane has antidepressant effects comparable to ECT, with less adverse effects on cognition. METHOD: Patients with medication-refractory depression received an average
View details →Negative / Null Result ReportOpen accessComputer Science
Xiaoqi Zhao, Hongpeng Jia, Youwei Pang et al. · 2026 · Machine Intelligence Research
Abstract Accurate medical image segmentation is critical for early medical diagnosis. Most existing methods are based on U-shape structure and use element-wise addition or concatenation to fuse different level features progressively in decoder. However, both the two operations easily generate plenty of redundant information, which will weaken the complementarity between different level features, resulting in inaccurate localization and blurred edges of lesions. To address this challenge, we propose a general multi-scale in multi-scale subtraction network (M 2 SNet) to finish diverse segmentati
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Silje Hogner, Terje Laskemoen, Jan T. Lifjeld et al. · 2012 · Ecology and Evolution
Mitochondrial DNA usually shows low sequence variation within and high sequence divergence among species, which makes it a useful marker for phylogenetic inference and DNA barcoding. A previous study on the common redstart (Phoenicurus phoenicurus) revealed two very different mtDNA haplogroups (5% K2P distance). This divergence is comparable to that among many sister species; however, both haplogroups coexist and interbreed in Europe today. Herein, we describe the phylogeographic pattern of these lineages and test hypotheses for how such high diversity in mtDNA has evolved. We found no evidenc
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Regula Gehrig, Bernard Clot · 2021 · Frontiers in Allergy
Climate change and human impact on vegetation modify the timing and the intensity of the pollen season. The 50 years of pollen monitoring in Basel, Switzerland provide a unique opportunity to study long-term changes in pollen data. Since…
View details →Negative / Null Result ReportPsychology
Tamlin S. Conner, Katie Reid · 2011 · Social Psychological and Personality Science
Does intensive focus on happiness change the naturalistic experience of happiness over time? In a 2-week text-messaging experiment, young adult participants ( n = 162) reported their current happiness 1, 3, or 6 times daily. Examination of…
View details →Negative / Null Result ReportPsychology
Kate Tchanturia, Eli A. Doris, Caroline Fleming · 2014 · European Eating Disorders Review
OBJECTIVE: This study aims to evaluate a novel and brief skills-based therapy for inpatients with anorexia nervosa, which addressed 'cold' and 'hot' cognitions in group format. METHOD: Adult inpatients with anorexia nervosa participated in…
View details →Negative / Null Result ReportOpen accessMedicine
Joakim Alfredsson, Johan Lindbäck, Lars Wallentin et al. · 2011 · European Heart Journal
AIMS: To assess gender differences in outcome with an early invasive or non-invasive strategy in patients with non-ST-elevation acute coronary syndromes (NSTE ACS). METHODS AND RESULTS: We included 46,455 patients [14 819 women (32%) and…
View details →Negative / Null Result ReportOpen accessMedicine
Jennifer L. Tenor, Stefan H. Oehlers, Jialu L. Yang et al. · 2015 · mBio
UNLABELLED: The human fungal pathogen Cryptococcus neoformans is capable of infecting a broad range of hosts, from invertebrates like amoebas and nematodes to standard vertebrate models such as mice and rabbits. Here we have taken advantage of a zebrafish model to investigate host-pathogen interactions of Cryptococcus with the zebrafish innate immune system, which shares a highly conserved framework with that of mammals. Through live-imaging observations and genetic knockdown, we establish that macrophages are the primary immune cells responsible for responding to and containing acute cryptoco
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Eva Morales, Alexandra Groom, Debbie A. Lawlor et al. · 2014 · BMC Research Notes
BACKGROUND: Epigenetic changes could mediate the association of maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) with adverse offspring outcomes. However, studies in humans are lacking. Here, we examined the association of maternal pre-pregnancy BMI and GWG in different periods of pregnancy with cytosine-guanine (CpG) dinucleotide site methylation differences in newborn cord blood DNA from 88 participants in the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort using the Illumina GoldenGate Panel I. Pyrosequencing was used for validation of the top a
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Sandrine Guerlet, Sourish Basu, A. Butz et al. · 2013 · Geophysical Research Letters
Column‐averaged dry air mole fractions of carbon dioxide (XCO 2 ) measured by the Greenhouse Gases Observing Satellite (GOSAT) reveal significant interannual variation (IAV) of CO 2 uptake during the Northern Hemisphere summer between 2009…
View details →Negative / Null Result ReportMedicine
George C.M. Siontis, J. P. A. Ioannidis · 2011 · International Journal of Epidemiology
BACKGROUND: Large studies may identify postulated risk factors and interventions with very small effect sizes. We aimed to assess empirically a large number of statistically significant relative risks (RRs) of tiny magnitude and their…
View details →Negative / Null Result ReportMedicine
Gary S. Solomon, Andrew W. Kuhn, Scott L. Zuckerman et al. · 2016 · The American Journal of Sports Medicine
BACKGROUND: A recent study found that an earlier age of first exposure (AFE) to tackle football was associated with long-term neurocognitive impairment in retired National Football League (NFL) players. PURPOSE: To assess the association…
View details →Negative / Null Result ReportOpen accessMedicine
Rebecca Abbott, Leon Straker, Svend Erik Mathiassen · 2013 · Obesity
OBJECTIVE: Sedentary behavior in children is positively associated with an increased risk of both obesity and insulin resistance. Children spend a considerable portion of their awake time in sedentary behavior; however, the pattern of…
View details →Negative / Null Result ReportOpen accessPsychology
Adam Oei, Michael D. Patterson · 2015 · Frontiers in Psychology
Despite increasing evidence that shows action video game play improves perceptual and cognitive skills, the mechanisms of transfer are not well-understood. In line with previous work, we suggest that transfer is dependent upon common demands between the game and transfer task. In the current study, participants played one of four action games with varying speed, visual, and attentional demands for 20 h. We examined whether training enhanced performance for attentional blink, selective attention, attending to multiple items, visual search and auditory detection. Non-gamers who played the game (
View details →Negative / Null Result ReportOpen accessMedicine
Bart G.P. Koot, Olga H. van der Baan‐Slootweg, Anneloes E. Bohte et al. · 2013 · Obesity
BACKGROUND: Accurate prediction scores for liver steatosis are demanded to enable clinicians to noninvasively screen for nonalcoholic fatty liver disease (NAFLD). Several prediction scores have been developed, however external validation…
View details →Negative / Null Result ReportOpen accessMedicine
Agnieszka Broda, Heather Jebbari, Kate Beaton et al. · 2012 · Journal of Clinical Microbiology
The isolation of rapidly growing mycobacteria (RGM), particularly Mycobacterium abscessus, from individuals with cystic fibrosis (CF) is associated with poor clinical outcome due to broad drug resistance and the difficulty of eradicating…
View details →Negative / Null Result ReportOpen accessMedicine
Anna Geke Algera, Luigi Pisani, Ary Serpa Neto et al. · 2020 · JAMA
Importance: It is uncertain whether invasive ventilation can use lower positive end-expiratory pressure (PEEP) in critically ill patients without acute respiratory distress syndrome (ARDS). Objective: To determine whether a lower PEEP…
View details →Negative / Null Result ReportOpen accessMedicine
Wilbur Y.W. Lew, Evelyn Bayna, Erminia Dalle Molle et al. · 2013 · PLoS ONE
BACKGROUND: Circulating subclinical lipopolysaccharide (LPS) occurs in health and disease. Ingesting high fatty meals increases LPS that cause metabolic endotoxemia. Subclinical LPS in periodontal disease may impair endothelial function. The heart may be targeted as cardiac cells express TLR4, the LPS receptor. It was hypothesized that recurrent exposure to subclinical LPS increases mortality and causes cardiac fibrosis. METHODS: C57Bl/6 mice were injected with intraperitoneal saline (control), low dose LPS (0.1 or 1 mg/kg), or moderate dose LPS (10 or 20 mg/kg), once a week for 3 months. Left
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