DNA methylation signatures in cord blood associated with maternal gestational weight gain: results from the ALSPAC cohort
Eva Morales; Alexandra Groom; Debbie A. Lawlor; Caroline L. Relton · 2014 · BMC Research Notes
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Epigenetic changes could mediate the association of maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) with adverse offspring outcomes. However, studies in humans are lacking. Here, we examined the association of maternal pre-pregnancy BMI and GWG in different periods of pregnancy with cytosine-guanine (CpG) dinucleotide site methylation differences in newborn cord blood DNA from 88 participants in the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort using the Illumina GoldenGate Panel I. Pyrosequencing was used for validation of the top a
Abstract by Eva Morales; Alexandra Groom; Debbie A. Lawlor; Caroline L. Relton, BMC Research Notes (2014) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/1756-0500-7-278