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19,885 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

The interconnection between obstructive sleep apnoea and spondyloarthritis: pathophysiology, clinical evidence, and future perspectives.

Belančić A, Rogoznica Pavlović M, Fajkić A et al. · 2026 · Rheumatology international

Obstructive sleep apnoea (OSA) and spondyloarthritis (SpA) are chronic inflammatory disorders associated with substantial cardiometabolic morbidity and impaired quality of life. Increasing evidence suggests that these conditions frequently…

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Negative / Null Result ReportOpen accessMedicine

Mulberrofuran A: A Multifunctional 2-Arylbenzofuran Flavonoid-Insights into Pharmacological Actions, Molecular Mechanisms, and Therapeutic Potential.

Qiu F, Ling C, Wang S et al. · 2026 · Molecules (Basel, Switzerland)

Mulberrofuran A (MFA), a natural product originally isolated from the root bark of Morus alba L. (Sang-Bai-Pi), is a structurally distinctive mulberry-derived 2-arylbenzofuran bearing a prenyl-related side chain. Although MFA has attracted…

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Negative / Null Result Report

Artificial Intelligence for Pediatric Vesicoureteral Reflux Assessment on Voiding Cystourethrography: A Scoping Evidence Map of Diagnostic Performance and Clinician-Assisted Interpretation

Baltrak YA, Deliaga H · 2026 · Preprint

Background: /Objectives: Vesicoureteral reflux (VUR) is an important pediatric urologic condition in which accurate grading on voiding cystourethrography (VCUG) may influence counseling, surveillance, antimicrobial prophylaxis, and…

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Negative / Null Result ReportOpen accessMedicine

Virtual Reality and Gamification for Assessing Technical Aptitude, Cognitive Abilities, and Personality Characteristics in Surgical Residency Selection: Validation Study.

Gazit N, Ben-Gal G, Eliashar R · 2026 · JMIR medical education

Background Assessment of technical aptitude, cognitive abilities, and personality characteristics is important in selecting candidates for surgical training. Currently, the selection of surgical training candidates does not systematically…

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Negative / Null Result ReportOpen accessMedicine

Clinical Outcomes and Safety of Stem Cell Therapy for Diabetic Foot Ulcers: A Cross-Sectional Analysis of Overlapping Meta-Analyses.

Du Y, Xu Z, Wen T et al. · 2026 · Diabetes, metabolic syndrome and obesity : targets and therapy

Purpose The care of diabetic foot ulcers (DFU) continues to be a notable clinical challenge. The efficacy and safety of stem cell therapies versus conventional treatments for DFU are debated. Cross-sectional analyses of meta-analyses…

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Negative / Null Result ReportOpen accessMedicine

Nurse Practitioner Opioid Prescribing Authority: A Comparative Policy Analysis of New Zealand, United States, and Australia.

Kyei EF, Kyei GK, Forson MM et al. · 2026 · Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing

Aim To examine nurse practitioner opioid prescribing authority across three countries, analyzing safety outcomes, workforce distribution patterns, access equity, and service to vulnerable populations using integrated nursing policy and…

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Negative / Null Result ReportOpen accessMedicine

Sport Participation and Nutrition in Students: A Scoping Review of Neuroendocrine and Autonomic Mechanisms Linking Lifestyle Behaviors to Cognitive and Academic Outcomes.

Tafuri MG, Monda V, La Marra M et al. · 2026 · Nutrients

Background/Objectives: Sport participation and nutrition are increasingly recognized as key determinants of cognitive function and academic achievement in student populations. However, the biological mechanisms underpinning these…

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Negative / Null Result ReportMedicine

From Framework to Practice: Evaluating the Uptake of Sensitivity Analyses in The National Institute for Health and Care Excellence Real-World External Control Arm Evidence.

Leahy TP, Keenan C, Robertshaw E et al. · 2026 · Value in health regional issues

Objectives Growing reliance on single-arm trials (SATs) is driving increased real-world external control arm (RW-ECA) use in health technology assessment submissions. However, concerns over residual confounding and unmeasured bias often…

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Negative / Null Result ReportMedicine

Phytotherapies and complementary therapies for erectile dysfunction: A focused secondary synthesis and critical clinical interpretation of the AFU/SFMS evidence base.

Lebâcle C, Kassab D, Faix A et al. · 2026 · The French journal of urology

Objectives To provide a focused secondary synthesis and critical clinical interpretation of the AFU/SFMS evidence base on phytotherapies and complementary therapies for erectile dysfunction (ED). Evidence acquisition The parent AFU/SFMS…

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Negative / Null Result Report

Practice Variation in Evidence-Based Infusion Therapy and Peripheral Intravenous Cannulation Among Nurses in a Tertiary Care Teaching Hospital: An Exploratory Cross-Sectional Study

Jahangeerbasha A, R HKV, R C · 2026 · Preprint

Abstract Background Peripheral intravenous catheters (PIVCs) are among the most frequently used vascular access devices in hospitalized patients and are essential for administering intravenous fluids, antibiotics, vasoactive medications,…

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Negative / Null Result ReportMedicine

EFFECTS OF GLP-1 RECEPTOR AGONISTS ON PERIODONTAL TISSUE: AN INTERDISCIPLINARY EVIDENCE MAPPING - SCOPING REVIEW.

Henriques JP, Weckwerth AVB, Santana ACP et al. · 2026 · Annales pharmaceutiques francaises

Objectives Diabetes mellitus and periodontal disease are highly prevalent chronic disorders linked by bidirectional inflammatory and oxidative pathways. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are emerging pharmacologic agents…

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Negative / Null Result ReportOpen accessMedicine

Association of ischaemic stroke/TIA with subsequent oral anticoagulant adherence in patients with atrial fibrillation: a scoping review.

Shukkoor AA, Turgeon RD, De Vera MA et al. · 2026 · BMJ open

Objectives This study aimed to investigate the association and potential causal relationship between ischaemic stroke/transient ischaemic attack (TIA) and oral anticoagulant (OAC) adherence using Bradford Hill's criteria and to determine…

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Negative / Null Result Report

Oleanolic Acid as an Adjunct in Type 2 Diabetes

Günther A, Bednarczyk-Cwynar B, Malinowski M · 2026 · Preprint

Background: Type 2 diabetes mellitus is a progressive cardiometabolic disease in which many patients require treatment intensification despite lifestyle intervention and evidence-based pharmacotherapy. Oleanolic acid, a pentacyclic…

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Negative / Null Result Report

Bayesian Evidence Synthesis under Heterogeneity

Edmar BA, Veen D, Klugkist I · 2026 · Preprint

Bayesian evidence synthesis (BES) provides a way of synthesising research without pooling effects, allowing for quantitative synthesise procedures when the more traditional common-effects and random-effects models cannot be used. BES can…

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