Negative / Null Result ReportOpen accessBiotechnology
Fitri Handajani, Nabil Nabil, Hanggara Rahmabrata · 2025 · Biomedical and Biotechnology Research Journal
Background: Eucheuma cottonii (EC) is a seaweed contains active compounds of alkaloids, flavonoids, saponins, and triterpenoids as antioxidants. Monosodium glutamate (MSG) is a chemical widely consumed as a flavor enhancer. The use of MSG in large amounts and for long durations triggers organ damage, including the kidneys, which is currently still a debate. This study aims to prove whether EC extract can reduce kidney damage due to MSG induction. Methods: This was an experimental animal study with probability sampling. Twenty-four Rattus norvegicus were divided into three groups: Group I witho
View details →Negative / Null Result ReportOpen accessMedicine
Tryness Munyapa, Thokozani Mzumara, Grace Ogbonna et al. · 2023 · Health Science Reports
Abstract Background and Aim Goldman Applanation Tonometry (GAT), the gold standard of tonometry, is used without fluorescein in low‐resource settings. Nevertheless, corneal biomechanics differ among population groups. Purpose The aim of the study is to assess the relationship between GAT findings with and without fluorescein among glaucomatous and nonglaucomatous adults in Malawi. Methods This was a cross‐sectional quantitative study involving 22 glaucoma patients and 22 nonglaucoma patients at Mzuzu Central Hospital. We used a purposive sampling technique to select participants into the two g
View details →Negative / Null Result ReportOpen accessSpecialties of internal medicine
elham abdelsamiee, Fatma farahat, Ahmad Hamed · 2021 · Zagazig Journal of Forensic Medicine and Toxicology
Background: Sex identification of human skeleton is essential for bioarcheological and forensic studies. Determination of Sex is important to establish personal identity. Sex identification accurately depends on the presence of complete remains. Aim: This study aimed to estimate sex from measurements of sacrum and coccyx by computed tomography (CT) of Libyan population. Subjects and methods: A cross-sectional study was carried out in Radiological center of Aljala Hospital of Benghazi and Benghazi Medical Center, Libya on 120 subjects who were divided into 60 males and 60 females. Sex was deter
View details →Negative / Null Result ReportOpen accessMedicine
Esma Altan, Elife Barmak, Ebru Karaca Umay et al. · 2025 · Gazi Medical Journal
Objective: Spasmodic dysphonia (SD) is a neurological movement disorder involving the laryngeal muscles. There are three main types: adductor, abductor, and mixed type. Adductor type is the most common and mixed type is the rarest. Botox, the gold standard in treatment, is applied to the affected muscle group according to the type of SD. Dysphagia often occurs as a side effect of botulinum toxin injection treatment in spasmodic dystonia. Dysphagia may sometimes be seen secondary to SD. Methods: This study included 8 patients with adductor SD without dysphagia and 8 healthy subjects. The total
View details →Negative / Null Result ReportOpen accessOrthopedic surgery
Michał Maciejewski, Piotr Janusz, Michalina Dudkiewicz et al. · 2023 · Chirurgia Narządów Ruchu i Ortopedia Polska
Introduction. Radial neck fractures in children are rare and account for 1-3% of all childhood trauma. Severe displacement of the fracture can lead to a higher incidence of complications, such as limited range of motion (ROM), pain, instability, neurovascular trauma, premature physeal closure, cubitus valgus, radial head overgrowth, avascular necrosis and improper ossification. The treatment outcome depends on the injury type, treatment method and presence of complications.Aim. The purpose of the study was to assess the outcome of patients treated with elastic-stable intramedullary nailing (ES
View details →Negative / Null Result ReportOpen accessMedicine
Quamrun Nahar, Farhana Sultana, Anadil Alam et al. · 2014 · PLoS ONE
Background There has been no population-based study on human papillomavirus (HPV) prevalence or its genotypes in Bangladesh; a country eligible for GAVI funding for HPV vaccine. Methods We used baseline survey data of a prospective cohort study that was conducted in one urban and one rural area of Bangladesh. A total of 997 urban and 905 rural married women, aged 13 to 64 years, were enrolled in the baseline during July-December, 2011. Information was collected on socio-demographic characteristics and potential risk factors for HPV infection followed by gynecological examination and collection
View details →Negative / Null Result ReportOpen accessMedical technology
Mona Makita, Shinichi Kawamoto, Momoko Nagai-Tanima et al. · 2025 · Biomedical Engineering Advances
The ground reaction force (GRF) waveform during countermovement jumps (CMJs) is considered to reflect neuromuscular coordination strategies; yet the biomechanical mechanisms distinguishing unimodal from bimodal patterns remain unclear. This study investigated the influence of countermovement depth and velocity on GRF waveform shape and examined their relationship with joint moments and work. Twenty-six healthy young women (age: 22.1 ± 1.1 years; height: 160.8 ± 4.0 cm; body weight: 53.5 ± 5.6 kg) performed CMJs, and GRF waveforms were categorised as unimodal and bimodal patterns. Jump-related
View details →Negative / Null Result ReportOpen accessMedicine
Tuantuan Li, Jing Xu, Yong Gao et al. · 2023 · European Journal of Medical Research
Abstract Objective To investigate the clinical significance and value of peripheral blood T lymphocyte subset in patients with asymptomatic novel coronavirus variant strains infection (OMICRON). Methods A retrospective analysis of 281 patients with asymptomatic OMICRON infection who were admitted and isolated to the Fuyang Second People's Hospital from March to April 2022 was conducted. With 32 normal people as the control group, T lymphocytes of the two groups (CD3 + T, CD3 + CD4 + T, CD3 + CD8 + T) were analyzed and the differences between the two groups were analyzed. CD4 + T lymphocytes be
View details →Negative / Null Result ReportOpen accessDentistry
Daiana Kelly Lopes HERNANDES, Cesar Augusto Galvão ARRAIS, Erick de LIMA et al. · Journal of Applied Oral Science
ABSTRACT Objective This in vitro study evaluated the effect of two different shades of resin cement (RC- A1 and A3) layer on color change, translucency parameter (TP), and chroma of low (LT) and high (HT) translucent reinforced lithium disilicate ceramic laminates. Material and Methods One dual-cured RC (Variolink II, A1- and A3-shade, Ivoclar Vivadent) was applied to 1-mm thick ceramic discs to create thin RC films (100 µm thick) under the ceramics. The RC was exposed to light from a LED curing unit. Color change (ΔE) of ceramic discs was measured according to CIEL*a*b* system with a standard
View details →Negative / Null Result ReportOpen accessSports medicine
Danielle G. Weekes MD, Jenna A. Feldman, Richard E. Campbell BS et al. · 2019 · Orthopaedic Journal of Sports Medicine
Objectives: Opioids are commonly prescribed for pain management following Arthroscopic Rotator Cuff Repair (ARCR). While their efficacy outweighs their risks in the short term, chronic opioid use is associated with significant adverse effects, such as dependence, endocrine imbalance or respiratory depression. The rate of chronic opioid use and dependence following ARCR is unknown. The purpose of this study is to determine the rate of chronic opioid use following ARCR and establish the effect of preoperative opioid education on reducing chronic consumption. A secondary aim is to determine if an
View details →Negative / Null Result ReportOpen accessDentistry
L Safi, A Adl, T Ebrahimi Moghadam · 2007 · مجله دانشکده دندانپزشکی اصفهان
Introduction: This study was aimed to evaluate and compare the amount of microleakage of two types of root end filling materials, white Pro Root MTA (Dentsply) and Iranian MTA (Root MTA).Methods and Materials: In this laboratory study, 34 extracted single root and canal human teeth were selected. Root canals were cleaned, shaped and obdurate. Experimental samples were divided randomly in to 2 groups of 15 specimens. Root tips were sectioned in perpendicular angel and root end cavities were prepared. In first group, white Pro Root MTA and in second group, Root MTA was used as root end filling m
View details →Negative / Null Result ReportOpen accessMedicine
Gerda Trutnovsky, MD, Brigitte Bliem, MD, Elfriede Greimel, PhD et al. · 2021 · Sexual Medicine
ABSTRACT: Introduction: Treatment for vulvodynia is challenging and a multidisciplinary approach is recommended. Aim: To examine the effectiveness, safety and treatment satisfaction of vulvovaginal microablative laser treatment for vulvodynia. Methods: Case study of women who received laser treatment as part of a multidisciplinary treatment program for vulvodynia. Subjective improvement was compared to a retrospective cohort of women treated for vulvodynia without LASER therapy. LASER treatment was offered to women with vulvodynia presenting to a gynecologic pain clinic of a tertiary universit
View details →Negative / Null Result ReportOpen accessMedicine
Waldo Lino Júnior, William Dias Belangero · 2005 · Acta Ortopédica Brasileira
Os autores estudaram os efeitos do laser Hólmio:Ítrio-Alumínio-Granada (Ho: YAG) sobre as dimensões do tendão (comprimento e largura proximal e distal) e sobre a celularidade e arranjo das fibras de colágeno em 20 ratos adultos, machos, brancos (Ratus Novergicus) da varidade Wistar. Os animais foram divididos em dois grupos de acordo com o tempo de seguimento (12 e 24 semanas) e de acordo com a forma de aplicação do laser (contínua e em dois pontos). Utilizou-se aparelho de laser de Hólmio (pulsátil, estado sólido, com ondas de 2,1 microns, com potência de 40 watts, ponteira OmniTip de 30º) .
View details →Negative / Null Result ReportOpen accessOphthalmology
Fiona J. Rowe, Laura Tremarco · 2010 · British and Irish Orthoptic Journal
Aim: To identify the effect of using different coloured bars on reading time for the bar reading task, along with an assessment of subject experience with different colour bars. Methods: Inclusion criteria were: visual acuity better than 0.5 logMAR, presence of binocular single vision, and ability to understand and perform bar reading. Measurements were taken of visual acuity, near point of convergence, interpupillary distance, Bagolini glasses and prism fusion range. Bar reading was timed and undertaken with and without five coloured bars for N5 and N12 print. Results: Forty subjects were rec
View details →Negative / Null Result ReportOpen accessMedicine
Ludmila Malariková, Kristýna Machová, Ivona Svobodová et al. · 2023 · PLoS ONE
To increase the effectiveness of education is appropriate to incorporate varied teaching methods with multisensory stimulation and with an emphasis on personal and emotional experiences. This study aims to compare the knowledge of biology subject matter acquired by second and fourth-grade primary students. The lesson occurred at a farm in the experimental group and at school in the control group. Students' knowledge levels were assessed before the lesson, after the lesson, after 14 days, after a month, and after six months. When the levels of knowledge after the lesson were compared between th
View details →Negative / Null Result ReportOpen accessMedicine
Wiryawan Permadi, Hartanto Bayuaji, Kevin Dominique Tjandraprawira et al. · 2021 · BMC Research Notes
Abstract Objective To compare the live birth rates (LBR) and neonatal outcomes of frozen cycle in vitro fertilization (IVF) with fresh cycle IVF in the Indonesian population. Results This was retrospective study using secondary data of IVF patients at a private fertility centre. Study recruitment was between 3/8/2018 and 31/12/2019. Total sampling included all patients undergoing oocyte retrieval and embryo transfer within recruitment period. Patients undergoing fresh IVF cycles and frozen IVF cycles were compared. 351 patients were recruited: 68.1% (239/351) underwent fresh cycles and 31.9% (
View details →Negative / Null Result ReportOpen accessMedicine
Meiqi Liu, Mengying Xu, Tiantian Tang · 2021 · Scientific Reports
Abstract Hepatectomy and transplantation are the main surgical therapies for HCC patients, and radiotherapy or chemotherapy is often used as adjuvant treatment. Researches have evaluated the independent predictors of HCC, but evidence for factors predicting the efficacy of chemotherapy is rare. Patients diagnosed with HCC between 2010 and 2015 from the SEER database were included and randomly divided into non-chemotherapy and chemotherapy groups. The predictors of CSS and OS were analyzed with the Cox proportional-hazards regression model and Fine and Gray’s competing risk model. Although ther
View details →Negative / Null Result ReportOpen accessSurgery
Edivaldo Massazo Utiyama, Maria Beatriz Sartor de Faria Rosa, Marina de Paula Andres et al. · 2015 · Acta Cirúrgica Brasileira
PURPOSE: To compare the inflammatory response of three different meshes on abdominal hernia repair in an experimental model of incisional hernia.METHODS: Median fascial incision and skin synthesis was performed on 30 Wistar rats. After 21 days, abdominal hernia developed was corrected as follows: 1) No mesh; 2) Polypropylene mesh; and, 3) Ultrapro(r) mesh. After 21 days, the mesh and surrounding tissue were submitted to macroscopic (presence of adhesions, mesh retraction), microscopic analysis to identify and quantify the inflammatory and fibrotic response using a score based on a predefined s
View details →Negative / Null Result ReportOpen accessSurgery
Samah Abdelfatah Eshiaty, Shimaa Abdelsattar, Dina Sweed et al. · 2023 · Egyptian Liver Journal
Abstract Background Early detection of biliary atresia (BA) is a great challenge providing the main useful way to improve its clinical consequence. Promising metabolomics provides an effective method for determining innovative biomarkers and biochemical ways for improving early diagnosis. This study aimed to determine the benefit of serum and urinary potential bile acid metabolites in the differentiation of BA from non-biliary atresia (non-BA) cases using tandem mass spectrometry (MS/MS). Fourteen bile acids metabolites were measured quantitively by MS/MS in serum and urine samples from 102 ch
View details →Negative / Null Result ReportOpen accessDemography. Population. Vital events
Martin Kreidl, Zuzana Žilinčíková · 2023 · Demographic Research
Background : Several studies show that cohabiting adult children have less frequent contact with their mothers than married adult children. We argue that these findings might be spurious due to confounding. Objective : Our aim is to replicate earlier research using more robust statistical instruments from the family of multi-level models with fixed effects, which are known to offer better control of omitted-variable bias. We also want to show the extent to which union-type effects vary across countries and by parenthood status. Methods : We use data from the SHARE survey. Mothers are the prima
View details →Negative / Null Result ReportOpen accessOrthopedic surgery
Preston Harrison BS, Sarah Kiriluk MD, Kevin Lee et al. · 2026 · Foot & Ankle Orthopaedics
Category: Midfoot/Forefoot, Bunion Diabetes Keywords: Ankle, Degenerative, Hindfoot Deformity Introduction/Purpose: Intraoperative fluoroscopy has become essential in orthopedic surgery, particularly with the rise of minimally invasive surgery (MIS) techniques. Despite the advantages of minimally invasive foot and ankle surgery, it raises concerns about radiation exposure to both patients and surgical staff. The purpose of this study was to evaluate fluoroscopy time and radiation dose (cumulative air kerma) associated with open versus MIS bunion correction, comparing the open modified Lapidus
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Guofeng Pan, Guofeng Pan, Guofeng Pan et al. · 2025 · Frontiers in Oncology
ObjectiveRadical gastrectomy for gastric cancer involves the en-bloc resection of the primary tumor and complete excision of the mesogastrium. However, the surgical boundaries and techniques for removing lymph nodes above the pylorus during gastric cancer surgery remain unclear. We aimed to investigate a novel, standardized approach for excising the right mesogastrium in gastric cancer patients undergoing suprapyloric lymphadenectomy, focusing on surgical techniques and outcomes.MethodsOur surgical technique includes identifying three key elements of the mesogastrium: the encircling portion, t
View details →Negative / Null Result ReportOpen accessOrthopedic surgery
Hao Liu, Weikai Chen, Tao Liu et al. · 2017 · Journal of Orthopaedic Surgery
Aim: To investigate the accuracy of pedicle screw placement based on preoperative computed tomography in comparison with intraoperative data set acquisition for spinal navigation system. Methods: The PubMed (MEDLINE), EMBASE, and Web of Science were systematically searched for the literature published up to September 2015. This review followed the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines. Statistical analysis was performed using the Review Manager 5.3. The dichotomous data for the pedicle violation rate was summarized using relative risk (RR) and 95% confid
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
FU Hua, ZHOU Guochao, CAI Rongmin, SONG Xin, YANG Dinghua · 2025 · Zhongguo aizheng zazhi
Background and purpose: The resistance of pancreatic cancer to albumin-bound paclitaxel affects the therapeutic effect and prognosis. Signal transducer and activator of transcription 3 (STAT3) is one of the important molecules regulating the chemotherapy sensitivity of cancer cells. The liposome BP1003 targeting the antisense oligonucleotide of STAT3 mRNA can inhibit the expression of STAT3 and increase the chemotherapy sensitivity. However, the effect of BP1003 on the sensitivity of pancreatic cancer cells to albumin-bound paclitaxel remains unclear. The purpose of this study was to investiga
View details →Negative / Null Result ReportOpen accessVeterinary medicine
Bo Yang, Zhi Biao Nan, Yan Zhong Li · 2025 · Frontiers in Veterinary Science
IntroductionStanding milkvetch (Astragalus adsurgens) is widely distributed in the wild in Eurasia and North America and has been bred for cultivated forage in China. Yellow stunt and root rot disease caused by Alternaria gansuense is the primary disease of standing milkvetch. A. gansuense promotes the production of swainsonine in the plant. This study aimed to determine the safety of standing milkvetch that is infected with A. gansuense as forage for animals.MethodsTwo-week-old specific pathogen-free (SPF) male white mice were fed a commercial mouse feed (CMF), healthy plant feed (HPF) and di
View details →Negative / Null Result ReportOpen accessMedicine
Ning Li, Jincai Huang, Yanghe Feng · 2020 · PLoS ONE
Background Cognitive ability refers to the ability to receive, process, store, and extract information. It is the most important psychological condition for people to successfully complete activities. Previous studies have shown that the design of the human-computer interface of the command and control system cannot exceed the cognitive ability of the operator of the command and control system, and it must match the cognitive ability of the operator in order to reduce the mental load intensity, and improve the accuracy, timeliness and work efficiency. However, previous researchers in the field
View details →Negative / Null Result ReportOpen accessSports
Atefe Eftekhari, Jalal Dehghanizade · 2022 · رشد و یادگیری حرکتی ورزشی
The aim of this study was to investigate the effect of self-movement on distance perception. The method of the present study is quasi-experimental. The statistical population of the present study was the students of Urmia University who were randomly selected as a sample of 60 students who were eligible to participate in the study and were randomly divided into three groups of 20 people including static group, dynamic group with treadmill speed 4 Km/h and the dynamic group were divided at a speed of 8 km/h. The test of walking blindfolded in a straight line to a previously observed target was
View details →Negative / Null Result ReportOpen accessMedicine
Zhongwei Yu, Chenhui Zhao, Anqing Yang et al. · 2025 · Scientific Reports
Abstract To investigate the correlation between serum sex hormone levels and clear cell renal cell carcinoma(ccRCC). The clinical data of male patients diagnosed with ccRCC and with simple renal cysts in our hospital from 2017 to 2023 were collected. The basic clinical data and serum sex hormone levels, including luteinizing hormone (LH), follicle stimulating hormone (FSH), estradiol(E2), prolactin (PRL), progesterone(P), and testosterone (T), were compared between patients with ccRCC and patients with simple renal cysts. A total of 56 male patients with ccRCC and 82 male patients with simple
View details →Negative / Null Result ReportOpen accessMedical technology
Jian Zhang, Guohai Sun, Lei Zhang et al. · 2025 · Journal of Medical Ultrasound
Background: This study aimed to investigate the effects of combining an ilioinguinal/iliohypogastric nerve block with an ultrasound-guided quadratus lumborum block during inguinal surgery in older patients. Methods: Between December 2020 and June 2023, 300 elderly patients who underwent inguinal surgery at our institution were randomly divided into an observation group (n = 150) and a control group (n = 150). The observation group received ultrasound-guided quadratus lumborum block in addition to ilioinguinal/iliohypogastric nerve block, whereas the control group received only ultrasound-guide
View details →Negative / Null Result ReportOpen accessEconomic theory. Demography
Kitti Dióssy · 2024 · Köz-gazdaság
Hungarian Életünk és mindennapjaink egyre nagyobb részére van befolyása a mesterséges intelligenciának (MI). A munkaerőpiacon már jelenlévő Y és Z generáció motivációja és attitűdje hatással van hosszú távon a vállalatok versenyképességére. Az MI előnyeinek felismerése mellett annak alkalmazása és az esetleges hátrányaihoz való alkalmazkodás is jelentős feladat. Kutatásomban arra fókuszálok, hogy feltárjam a fiatal közgazdászok gondolkodásmódját az MI-vel kapcsolatban, anonim kérdőívek segítségével (147 magyar, 105 amerikai válaszadó). Ennek érdekében amerikai (fejlett gazdaság és élen járó az
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