Negative / Null Result ReportOpen accessMedicine
Ryo Obata, Yasuo Yanagi · 2014 · PLoS ONE
Purpose It has not been clarified whether early age-related macular degeneration (AMD) is associated with cone photoreceptor distribution. We used adaptive optics fundus camera to examine cone photoreceptors in the macular area of aged patients and quantitatively analyzed its relationship between the presence of early AMD and cone distribution. Methods Sixty cases aged 50 or older were studied. The eyes were examined with funduscopy and spectral-domain optical coherence tomography to exclude the eyes with any abnormalities at two sites of measurement, 2° superior and 5° temporal to the fovea.
View details →Negative / Null Result ReportOpen accessAgriculture
M. Amerian, S. E. Hashemi Garmdareh, A. Karami · 2020 · علوم آب و خاک
Today, one of the biggest challenges facing the world is the lack of water, especially in the agricultural sector. In this research, we investigated the effects of irrigation method and deficit irrigation with the urban refined effluent on biomass, grain yield, yield components and water use efficiency in single grain crosses 704 maize. This research was carried out in a randomized complete block design with two irrigation systems (furrow irrigation (F) and drip irrigation (T)) and three levels of deficit irrigation treatments of 100 (D1), 75 (D2) and 55 (D3) percent of water requirements in t
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Diego Raimondo, Antonio Raffone, Antonio Raffone et al. · 2022 · Frontiers in Oncology
Data about the oncological outcomes in women with borderline ovarian tumor (BOT) undergoing uterine-sparing surgery without ovarian preservation are poor. We aimed to assess the oncological outcomes in women with BOT undergoing uterine-sparing surgery without ovarian preservation. A multi-center observational retrospective cohort study was performed including all consecutive postmenopausal patients who underwent surgical treatment for BOT at three tertiary level referral centers for gynecologic oncology from January 2005 to December 2016. Patients were divided into two groups for comparisons:
View details →Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Chanchal Katariya, Arvina Rajasekar · 2022 · Journal of Advanced Pharmaceutical Technology & Research
Microsurgery is a minimally invasive procedure that uses a surgical microscope, specially designed equipment, and suture materials. Even though this equipment and expertise of numerous surgeries are required to meet patient esthetic reckoning, doctors must be ready to invest time and effort into becoming familiar with novel surgical methods and devices. The ambition of this case series is to compare conventional macro surgery and microsurgery in terms of clinical approach. This study included four cases, two flap surgery, and two root coverage. Clinical parameters for root coverage, increase i
View details →Negative / Null Result ReportOpen accessScience (General)
Akeem Dauda Babatunde, Hafsah Maiazara Adamu, Hauwau Abubakar Salele · 2023 · UMYU Scientifica Journal
The study was conducted over a period of fifty-six (56) days to investigate the effects of different colours of culture tanks on the water quality, growth, and feed utilization of Nile tilapia (Oreochromis niloticus) juveniles. O. niloticus of mean body weight of 8.5g were stocked and fed twice daily with a commercial diet containing 42% crude protein. The experiment had four treatments based on tank colours; white, green, black and blue coloured tanks. Some water quality indices were assessed once in a week while the fish were weighed at the end of the experiment to compute the performance in
View details →Negative / Null Result ReportOpen accessAnimal culture
Cut Nila Thasmi, Nuzul Asmilia, Elfi Satria Suryani et al. · 2022 · Jurnal Kedokteran Hewan
This study aims to analyze the effect of administering Malacca leaves (Phyllanthus emblica) extract on the sperm quality of mice. This leaf extract was administered orally using gavage method once daily for 21 days. There were four treatment groups: the control group (P0) received distilled water while the first (P1), second (P2), and third (P3) treatment groups received 300 mg, 600 mg, and 1200 mg of Malacca leaf ethanol extract/kg body weight, respectively. Each groups consisted of four mice and was evaluated for sperrm motility, viability, morphology, and concentration. The results showed t
View details →Negative / Null Result ReportOpen accessAnimal culture
Jing-ping GAO, Jia-ning SUN, Xian-hua LI et al. · 2021 · Siliao yanjiu
The experiment was to study the effect of the combination of glucose oxidase (GOD) and Lactobacillus on growth performance and immune function of broilers. A total of 1 200 one-day-old AA broilers were randomly divided into four groups: group Ⅰ (control group), group Ⅱ, group Ⅲ and group Ⅳ. The control group was free to drink water, group Ⅱ was added 0.1% GOD in the drinking water of each chicken daily, and group Ⅲ was added 1.5×10 5 CFU/g Lactobacillus preparation in the drinking water of each chicken daily. In test group Ⅳ, 0.1% GOD and 1.5×10 5 CFU/g Lactobacillus were added to each chicken
View details →Negative / Null Result ReportOpen accessDentistry
Ganesh RamKumar Rajapandi, Ahila Singaravel Chidambaranathan, MuthuKumar Balasubramanium · 2025 · Biomaterial Investigations in Dentistry
Introduction: Debonding of silicone prostheses from metal substructures is a frequently reported complication in prosthodontics. Polyether ether ketone (PEEK) has emerged as a promising alternative framework material owing to its favourable biomechanical properties; however, its limited bond strength to silicone remains a concern. The present study aimed to evaluate the shear bond strength between PEEK and maxillofacial silicone following laser etching of PEEK and subsequent accelerated ageing. Materials and methods: According to ISO 10477:2020, 128 PEEK specimens were fabricated using Compute
View details →Negative / Null Result ReportOpen accessScience
Hans IJzerman, Jaap J. A. Denissen · 2019 · Royal Society Open Science
We report a replication and extension of a finding from Studies 1 and 2 of Van Lange et al.'s influential paper (Van Lange et al. 1997 J. Pers. Soc. Psychol. 73, 733–746. (doi:10.1037/0022-3514.73.4.733)), which showed an association between Social Value Orientation (SVO) and attachment security. We report a close replication but with measures of attachment that are considered superior in comparison to measures used by Van Lange et al., due to subsequent psychometric improvements. Psychometric analyses indeed showed that our attachment measures were reliable and valid, demonstrating theoretica
View details →Negative / Null Result ReportOpen accessMedicine
Mojtaba Khazaei, Fatemeh Saadati Pour, Masoud Ghiasian et al. · 2024 · مجله علوم پزشکی فیض (پیوسته)
Background and Aim: Edaravone is known for its efficacy in inhibiting free radical formation, activating microglia, and promoting neurogenesis and neuroprotection following acute ischemic stroke. This clinical trial aimed to investigate the effects of Edaravone on clinical symptoms and oxidative stress factors in patients with acute ischemic stroke. Methods: In this clinical trial, fifty-two patients diagnosed with acute ischemic stroke were randomly assigned to receive either Edaravone (120 mg daily up to 3 doses intravenously) or a placebo in addition to standard treatment. Stroke severity w
View details →Negative / Null Result ReportOpen accessMedicine (General)
Seoyoung Wy, Seoyoung Wy, Young Kook Kim et al. · 2022 · Frontiers in Medicine
PurposeTo compare the clinical outcomes of maximum tolerated medical therapy (MTMT) in patients with penetrating keratoplasty (PKP) with those of Ahmed glaucoma valve (AGV) implantation.MethodsThe medical records were retrospectively reviewed in patients who had undergone PKP for bullous keratopathy and were treated with MTMT or AGV implantation for the management of glaucoma. A total of 18 bullous keratopathic patients were investigated between January 2010 and February 2017: 9 patients treated with MTMT and 9 patients treated with AGV implantation. Non-corrected visual acuity (NCVA), intraoc
View details →Negative / Null Result ReportOpen accessVeterinary medicine
Andra DEGAN, Ruxandra TUDOR, Ruxandra COSTEA et al. · 2019 · Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Veterinary Medicine
General anesthesia produces different degrees of central nervous depression and changes in the peripheral circulation, therefore affecting the patient’s thermoregulatory mechanism. Moreover, the lack of proper, specially designed equipment for magnetic resonance imaging (MRI) environment monitoring can represent a challenge for the anesthetist. We examined the temperature variations correlated with different anesthetic protocols in dogs that underwent general anesthesia in order to evaluate changes in rectal and distal extremities temperature, before and after anesthesia. This study was conduc
View details →Negative / Null Result ReportOpen accessMedicine (General)
Martins MJ, Martins CPMO, Castro-Alves LJ et al. · 2018 · Journal of Pain Research
Marcelo J Martins,1 Caroline Paiva Matos Oliveira Martins,2 Lucas J Castro-Alves,3 Gabriel Nascimento Jesus,4 Guilherme Oliveira Campos,5 Breno Barbosa Cerqueira Sacramento,4 Leonardo Ferrari Borges,6 Carlos Augusto Bastos Mello,6 Rodrigo Leal Alves,5 Norma Sueli Pinheiro Módolo7 1Department of Anesthesiology, São Paulo State University (UNESP), São Paulo, Brazil; 2Department of Anesthesiology at Federal University of Bahia, Bahia, Brazil; 3Department of Anesthesiology, Santo Antonio Hospital, Salvador, Bahia, Brazil; 4Department of Anesthesia, Bahia University of Medicine
View details →Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Xingtao Ge, Xinghua Ge, Chen Wang et al. · 2022 · BMC Musculoskeletal Disorders
Abstract Background A safe and effective technique for anterolateral portal placement in elbow arthroscopy is significant. We compared the outcomes of patients who underwent elbow arthroscopy using different ultrasound-assisted techniques. Methods From May 2016 to June 2021 a retrospective analysis on all patients who underwent elbow arthroscopy in our department was performed. Patients were separated into three groups: non-ultrasound; preoperative ultrasound; and intraoperative ultrasound. The minimum follow-up period was 1 year. Nerve injuries, visual analog scale (VAS), Mayo elbow-performan
View details →Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Maryam Sharifi, Shahrbanoo Oryan, Alireza Komaki et al. · 2023 · IBRO Neuroscience Reports
There is growing evidence that the hippocampus comprises diverse neural circuits that exhibit longitudinal variation in their properties, however, the intermediate region of the hippocampus has received comparatively little attention. Therefore, this study was designed to compared short- and long-term synaptic plasticity between the dorsal and intermediate regions of the hippocampus in normal and PTZ-kindled rats. Short-term plasticity was assessed by measuring the ratio of field excitatory postsynaptic potentials’ (fEPSPs) slope in response to paired-pulse stimulation at three different inter
View details →Negative / Null Result ReportOpen accessAgriculture
Preetaman Bajwa, Rupinder Saini, Sukhbir Singh et al. · 2025 · Agrosystems, Geosciences & Environment
Abstract Industrial hemp is receiving attention for its numerous benefits, particularly in the fiber industry. Weed competition is a primary concern for hemp cultivation, causing reduced yields and inferior‐quality fiber. However, little is known about herbicide application in hemp since a limited range of herbicides are available for hemp production. During 2023, this study evaluated the effect of different post‐emergence herbicides applied at early and late growth stages to optimize weed suppression and minimize crop injury in hemp under semiarid conditions. A randomized complete block desig
View details →Negative / Null Result ReportOpen accessScience (General)
Shenkute Goshme, Tadiws Asfaw, Chekol Demiss et al. · 2021 · Heliyon
The frozen bull semen straws were gathered from three specifically chosen locations in the North Shewa Zone, namely Baso, Chacha, and Debre-Birhan town, and the laboratory work was carried out at the Debre Birhan agricultural research center. The researchers wanted to see how different thawing methods affected the mass motility of frozen bull sperm. The thawing protocols used for mass motility evaluation were 37 °C for 30 s, 35 °C for 40 s, 40 °C for 40 s, body temperature using a hand for 15 s and body temperature using a hand for 30 s by using a water bath. The mass motility of the frozen bu
View details →Negative / Null Result ReportOpen accessMedicine (General)
Madeleine M. Southey, Trent Rees, Margaret Rolfe et al. · 2019 · Addiction Science & Clinical Practice
Abstract Background Residential opioid rehabilitation aims to improve the mental health and quality of life of opioid users through abstinence and residential program participation. This study aimed to determine the depression, anxiety, stress and quality of life amongst maintenance to abstinence (MTA) program residents. Secondary study aims were to assess the personal characteristics of MTA clients, addiction and risk taking behaviours, factors associated with program completion, as well as to assess the reliable change in participants’ mental health and quality of life on exit. Methods Retro
View details →Negative / Null Result ReportOpen accessScience
Shan Zhang, Shu Wu, Yiru Shen et al. · 2020 · Royal Society Open Science
Magnetic Fe3O4 nanoparticles (Fe3O4-NPs) have been widely investigated for their biomedical applications. The main purpose of this study was to evaluate the cytotoxic effects of different sizes of Fe3O4-NPs in chicken macrophage cells (HD11). Experimental groups based on three sizes of Fe3O4-NPs (60, 120 and 250 nm) were created, and the Fe3O4-NPs were added to the cells at different doses according to the experimental group. The cell activity, oxidative index (malondialdehyde (MDA), superoxide dismutase (SOD) and reactive oxygen species (ROS)), apoptosis and pro-inflammatory cytokine secretio
View details →Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Waqas Akhtar, Charles Butcher, Andrew Morley‐Smith et al. · 2022 · ESC Heart Failure
Abstract Aims We present a single‐centre retrospective experience using oral milrinone in patients with a left ventricular assist device (LVAD) and concurrent refractory right ventricular failure. Methods and results All patients implanted with LVAD between January 2013 and July 2021 from a high‐volume advanced heart failure service were reviewed. Eight patients were initiated on oral milrinone during this period. Oral milrinone was started 1.5 [inter‐quartile range (IQR) 1–2.3] years after LVAD implantation and continued for 1.2 (IQR 0.5–2.8) years. Therapeutic milrinone levels were achieved
View details →Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Dan Zhu, Zhenzhen Fan, Fujun Cheng et al. · 2022 · Brain Sciences
Objectives: To investigate the efficacy and safety of an improved ultrasound-guided pulsed radiofrequency (PRF) and nerve block (NB) for patients with pudendal neuralgia (PN). Methods: This retrospective analysis included 88 adults with PN treated in the Pain Department of Southwest Hospital from November 2011 to June 2021, with treatment including NB ( n = 40) and PRF ( n = 48). The primary outcome variable was pain severity, measured by a standardized visual analog scale (VAS). VAS values were collected at 1, 3, 7, and 14 days and 1 and 3 months after patients were treated with NB or PRF. Re
View details →Negative / Null Result ReportOpen accessMedicine
CHEN Zhu, LIU Yan, GAO Li-hua, CHEN Bu-you, TANG Ai-hua, LIU Jun · 2021 · Jichu yixue yu linchuang
Objective To evaluate the efficacy and safety of apatinib in the treatment of metastatic colorectal cancer (mCRC). Methods Sixty-five patients with mCRC treated with apatinib were enrolled in this study for retrospective analysis. The factors affecting the recent effective, progression-free survival (PFS) and adverse reactions were evaluated. Results The disease control rate in 63 evaluable patients was 69.9%. The median PFS for patients received first-line, second-line, and third-line and above apatinib treatment were 9.3 months, 5.8 months, and 3.3 months, respectively(P＜0.001). The PFS in t
View details →Negative / Null Result ReportOpen accessOphthalmology
Lin Y, Luo S, Lu Q et al. · 2024 · Clinical Ophthalmology
Ye Lin, Shuke Luo, Qiang Lu, Xueke Pan Department of Ophthalmology, The Second People’s Hospital of Foshan, Foshan, Guangdong Province, People’s Republic of ChinaCorrespondence: Shuke Luo, Department of Ophthalmology, The Second People’s Hospital of Foshan, Foshan, Guangdong Province, 528000, People’s Republic of China, Tel +86 13679830510, Email 542377993@qq.comPurpose: To investigate the psychological changes in patients pre and post implantable collamer lens (ICL, EVO) implantation surgery in the posterior chamber.Patients and methods: Self-rating anxiety scale (SAS) and self-rating depress
View details →Negative / Null Result ReportOpen accessMedical emergencies. Critical care. Intensive care. First aid
V. A. Shmyrev, D. N. Ponomarev, P. P. Perovsky et al. · 2014 · Общая реаниматология
Objective: to comparatively evaluate the perioperative clinical period in patients operated on via miniinvasive access and median sternotomy.Subjects and methods. A retrospective analysis included all patients who had undergone correction of mitral valve defect with or without tricuspid valve correction and atrial ablation. 121 and 112 patients were operated on through miniinvasive access (a study group) and median sternothomy (a control group), respectively.Results. The duration (median [25; 75 percentiles] of aortic occlusion in the study group (89 [71; 120] min) was significantly longer tha
View details →Negative / Null Result ReportOpen accessScience
Livhuwani E. Nephale, Ngonidzashe A.G. Moyo, Mmaditshaba M. Rapatsa-Malatji · 2024 · Scientific African
An 8-week feeding trial was conducted to evaluate the effect of Alates termite (Macrotermes falciger) based diet in a herbivorous (Oreochromis mossambicus) and an opportunistic predator (Clarias gariepinus). Five diets were formulated to replace fishmeal at 0, 10, 30, 50, and 70 % and were denoted D1, D2, D3, D4, and D5, respectively. Clarias gariepinus sub-adults (209.24 ± 2.41 g/fish) were stocked at 5 fish per tank in recirculating fibreglass tanks (400 L) in triplicates. Oreochromis mossambicus juveniles (7.4 ± 4.78 g/fish) were randomly stocked at 10 fish per tank in recirculating fibregl
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Lina Jans, Jan Brynhildsen, Joar Hofgaard et al. · 2025 · Infectious Agents and Cancer
Abstract Background Users of intrauterine devices (IUDs) have been found to have a lower incidence of cervical cancer in meta-analyses, but these studies have not been able to examine the influence of IUD type. The aim of this study is to investigate the incidence of de novo high-risk human papillomavirus (HPV) infections in relation to the reported use of contraceptive methods, with special regard to different types of IUDs. Methods A sample of participants in the national screening program for cervical cancer (n = 11,702) with a negative HPV test in 2017–2018 were included. Their subsequent
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Guodong Zhang, Jijun Li, Jun Tang et al. · 2019 · BMC Pregnancy and Childbirth
Abstract Background The aim of this study was to assess the feasibility, safety and outcome of the embolization of non-gonadal collateral supplying gestational sac (GS) in addition to uterine artery embolization (UAE), followed by hysteroscopic curettage for the management of cesarean scar pregnancy (CSP). Methods A retrospective study was undertaken from January 2012 to September 2018 in 24 CSP patients in whom non-gonadal collaterals supplying GS were identified by arterial angiography performed immediately after UAE. These patients underwent attempt collateral embolization in addition to UA
View details →Negative / Null Result ReportOpen accessNursing
Nahid Mohammadi, Nasrin Soltani, Roya Amini et al. · 2018 · مراقبت پرستاری و مامایی ابن سینا
Introduction: Cardiovascular diseases are associated with individual behaviors in childhood, adolescence and youth. This article aimed to study the effect of education based on HBM on the prevention of heart disease in female students. Methods:This pre and post-test semi-experimental study which has two groups was conducted on 126 girls of high schools in 2017. A randomized cluster sampling method and relative randomize method were used in the first and second stages respectively. At first both groups completed a questionnaire and then instructions were given to intervention group in three ses
View details →Negative / Null Result ReportOpen accessPsychology
Miroslava Galasová, Matúš Grežo · 2021 · Studia Psychologica
The theory of action versus state orientation suggests that state-oriented people are more susceptible to sunk cost fallacy than action-oriented people because they ruminate about past costs and are reluctant to change their course of actions. However, research on the role of action versus state orientation in sunk cost fallacy is fairly limited. Therefore, the present paper aims to conceptually replicate the seminal study by van Putten et al. (2010) and verify whether action versus state orientation really matters in the susceptibility to sunk cost fallacy. We also examined the role of gender
View details →Negative / Null Result ReportOpen accessCytology
MĂźzeyyen Ozhavzali, UlkĂź Yazici, Funda Demirag et al. · 2010 · Folia Histochemica et Cytobiologica
This study investigated the immunohistochemical staining characteristics of glutathione-S-transferase alpha, pi, mu, theta and p53 in non-small cell lung carcinoma and normal lung tissue from 50 patients. The relationships between expressions of the Glutathione-S-transferase isoenzymes and some clinicopathological features were also examined. Expression of glutathione-S-transferase pi, mu, alpha, theta and p53 was assessed by immunohistochemistry for primary lung carcinomas of 50 patients from the Sanitarium Education and Research Hospital, Ankara lung cancer collection. The relationships betw
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