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19,815 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance

Determinants of Green Energy Penetration in N-11 Countries: A Machine Learning Analysis

Najabat Ali, Md Reza Sultanuzzaman · 2026 · Energies

This study investigates the determinants of green energy penetration in the Next Eleven (N-11) economies over the period 2000–2022, with a particular focus on the roles of foreign direct investment (FDI), green transition, governance quality, industrial growth, and urbanization. The primary objective of the study is to assess how investment flows, structural transformation, and institutional capacity jointly shape the adoption of renewable energy in fast-growing emerging economies. To achieve this goal, the study employs a second-generation panel econometric and machine-learning framework that

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Negative / Null Result ReportOpen accessMedicine

Antibody drug conjugate targets are highly differentially expressed across the major types of ovarian cancer

Joanna M Porter, Cici Jin, Michael Churchman et al. · 2025 · European Journal of Cancer

BACKGROUND: Antibody-drug conjugates (ADCs) are emerging anti-cancer agents. The folate receptor alpha (FOLRα)-directed ADC mirvetuximab soravtansine recently demonstrated clinical activity in platinum-resistant ovarian cancer, with other ADCs currently in development. The relative expression of FOLRα and other ADC targets is largely unknown across ovarian cancer histotypes. METHODS: Expression levels of the ADC targets FOLRα, TROP2 and B7-H4 were assessed by immunohistochemistry in patient cohorts using tumour tissue microarrays of the major ovarian cancer histotypes: high grade serous (HGSOC

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Negative / Null Result ReportOpen accessComputer Science

Biased AI writing assistants shift users’ attitudes on societal issues

Sterling Williams-Ceci, Maurice Jakesch, Advait Bhat et al. · 2026 · Science Advances

Artificial intelligence (AI) writing assistants powered by large language models (LLMs) are increasingly used to make autocomplete suggestions to people as they write text. Can these AI writing assistants affect people’s attitudes in this…

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Negative / Null Result ReportOpen accessMedicine

Osteoarthritis: molecular pathogenesis and potential therapeutic options

Yi Zhang, Yanqi Han, Ying Sun et al. · 2026 · Signal Transduction and Targeted Therapy

Osteoarthritis (OA) is a debilitating joint disorder that causes chronic pain, inflammation, and detrimental bone alterations. Despite significant advances in understanding OA pathogenesis, current therapeutic strategies remain inadequate in halting disease progression or providing effective pain relief, highlighting unmet clinical needs. Recent insights into OA nociceptive pathways, inflammatory mediators, and organelle dysfunction have revealed promising therapeutic targets. Specifically, OA progression is driven by mitochondrial dysfunction (marked by accumulated damaged mitochondria with e

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Negative / Null Result ReportOpen accessMedicine

Distinct brain alterations and neurodegenerative processes in cognitive impairment associated with post-acute sequelae of COVID-19

Dayoung Seo, Yangsean Choi, Eunseon Jeong et al. · 2025 · Nature Communications

Although brain alterations have been reported in post-acute sequelae of SARS-CoV-2 (PASC), their prevalence and relationship to neurodegeneration remain unclear. We analyzed blood proteins and brain MRI from individuals approximately one…

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Negative / Null Result Report

13C Labelling of Litter Added to Tea (Camellia sinensis L.) Plantation Soil Reveals a Significant Positive Priming Effect That Leads to Less Soil Organic Carbon Accumulation

Xiangde Yang, Kang Ni, Lifeng Ma et al. · 2022 · Agronomy

Although annual return of litter occurs in tea (Camellia sinensis L.) plantations, the level of soil organic carbon (SOC) therein remains relatively low. The exact impacts of pruned litter on soil and its association with SOC accumulation…

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Negative / Null Result Report

Did Expanded Dental Insurance Reduce Out-of-Pocket Expenditures on Dental Care among Older Adults in Korea? Interrupted Time-Series Analysis

Nam-Hee Kim, Se-Hwan Jung, Ichiro Kawachi · 2021 · International Journal of Environmental Research and Public Health

The Korean National Health Insurance extended its coverage to reduce the economic burden of receiving dentures and implants for older adults in 2012 and 2014, respectively. We examined whether the new policy resulted in reduced…

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Negative / Null Result Report

Effect of Significant Postoperative Complications on Decision Regret After Laparoscopic Sleeve Gastrectomy: a Case–Control Study

Katarzyna Bartosiak, Michał R. Janik, Maciej Walędziak et al. · 2022 · Obesity Surgery

Abstract Background Thus far, no data are available on decision regret about sleeve gastrectomy (SG), particularly in patients who experienced perioperative complications. This study aimed to assess whether patients with postoperative…

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Negative / Null Result Report

Significant Prognostic Factors Influencing the Survival Difference of Oral Tongue Squamous Cell Carcinoma

Sarinya Boonpoapichart, Pattama Punyavong, Kamonwan Jenwitheesuk et al. · 2021 · Plastic and Reconstructive Surgery - Global Open

Background: Oral tongue squamous cell carcinoma is the most common malignancy in the oral cavity. Overall survival varies across many countries, and poor prognosis is prevalent in developing countries, including Thailand. Our study aimed…

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Negative / Null Result Report

Does the Establishment of National New Areas Improve Urban Ecological Efficiency? Empirical Evidence Based on Staggered DID Model

Jingbin Wang, Huiling Qiao, Jing Liu et al. · 2022 · International Journal of Environmental Research and Public Health

The environmental effects of national new areas have been an important topic but received little attention in academia. This study conducts a quasi-natural experiment using panel data of China’s 282 prefecture-level cities from 2006 to…

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Negative / Null Result Report

Biologically relevant small variations of intra-cellular pH can have significant effect on stability of protein–DNA complexes, including the nucleosome

Alexey V. Onufriev · 2023 · Frontiers in Molecular Biosciences

Stability of a protein-ligand complex may be sensitive to pH of its environment. Here we explore, computationally, stability of a set of protein-nucleic acid complexes using fundamental thermodynamic linkage relationship. The nucleosome,…

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Negative / Null Result Report

Significant sex difference in the association between C‐reactive protein concentration and anthropometry among 13‐ to 19‐year olds, but not 6‐ to 12‐year olds in Nepal

Shoko Konishi, Rajendra Prasad Parajuli, Erica Takane et al. · 2014 · American Journal of Physical Anthropology

ABSTRACT Life history theory predicts a trade‐off between immunostimulation and growth. Using a cross‐sectional study design, this study aims to test the hypothesis that C‐reactive protein (CRP) is negatively associated with height‐for‐age…

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Negative / Null Result Report

Inflation in 2022 did not affect congressional voting, but abortion did

Diana C. Mutz, Edward D. Mansfield · 2024 · Proceedings of the National Academy of Sciences

This study examines voting in the 2022 United States congressional elections, contests that were widely expected to produce a sizable defeat for Democratic candidates for largely economic reasons. Based on a representative national…

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Negative / Null Result Report

The Relationship between Obsessive Compulsive Personality and Obsessive Compulsive Disorder Treatment Outcomes: Predictive Utility and Clinically Significant Change

Shalane K. Sadri, Peter M. McEvoy, Sarah J. Egan et al. · 2017 · Behavioural and Cognitive Psychotherapy

Background: The evidence regarding whether co-morbid obsessive compulsive personality disorder (OCPD) is associated with treatment outcomes in obsessive compulsive disorder (OCD) is mixed, with some research indicating that OCPD is…

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Negative / Null Result Report

Evening Caffeine Did Not Improve 100-m Swimming Time Trials Performed 60 Min Post-Ingestion or the Next Morning After Sleep

Josh W. Newbury, Bryan Saunders, Lewis A. Gough · 2022 · International Journal of Sport Nutrition and Exercise Metabolism

The potential ergogenic benefits of caffeine (CAF) are well known within the athletic community, often leading to its use in adolescent swimming cohorts to enhance their performance. However, it has previously been reported that CAF has…

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Negative / Null Result Report

Subclinical Systemic Sclerosis Primary Heart Involvement by Cardiovascular Magnetic Resonance Shows No Significant Interval Change

Raluca B. Dumitru, Lesley‐Anne Bissell, Bara Erhayiem et al. · 2023 · ACR Open Rheumatology

Objective Subclinical systemic sclerosis (SSc) primary heart involvement is commonly described. Whether these findings progress over time is not clear. The study aimed to investigate cardiovascular magnetic resonance (CMR) interval change…

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Negative / Null Result Report

CURING HEPATITIS C WITH THE NEW DIRECT ACTING ANTIVIRALS DID NOT IMPROVE INSULIN RESISTANCE AFTER ONE YEAR

Lohanna STRAUHS-NITSCH, Marcela Ferro CAMPIOLO, Daphne Benatti Gonçalves MORSOLETTO et al. · 2020 · Arquivos de Gastroenterologia

ABSTRACT BACKGROUND: Chronic hepatitis C still figures as an important cause of morbidity among the Brazilian population, and is closely associated with metabolic disturbances, including insulin resistance (IR), which can be evaluated by…

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