Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Rodrigo Lasa, Laura Navarro-de-la-Fuente, Anne Gschaedler et al. · 2019 · Insects
Specific ecological interactions between insects and microbes have potential in the development of targeted pest monitoring or control techniques for the spotted wing drosophilid, Drosophila suzukii (Matsumura), an exotic invasive pest of soft fruit. To evaluate D. suzukii attraction to yeast species from preferred types of fruit, three yeasts were isolated from blackberry fruit and two yeasts from raspberry fruit and used to bait simple plastic bottle traps. Saccharomyces cerevisiae and Hanseniaspora uvarum were identified from blackberries, whereas a different H. uvarum strain was identified
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Anthony Laybros, Daniel Schläpfer, Jean‐Baptiste Féret et al. · 2019 · Remote Sensing
Imaging spectroscopy is a promising tool for airborne tree species recognition in hyper-diverse tropical canopies. However, its widespread application is limited by the signal sensitivity to acquisition parameters, which may require new training data in every new area of application. This study explores how various pre-processing steps may improve species discrimination and species recognition under different operational settings. In the first experiment, a classifier was trained and applied on imaging spectroscopy data acquired on a single date, while in a second experiment, the classifier wa
View details →Negative / Null Result ReportMedicine
Kotaro Matsumoto, Katsuya Suzuki, Keiko Yoshimoto et al. · 2019 · Lara D. Veeken
OBJECTIVES: To elucidate the association between clinical characteristics and immuno-phenotypes in patients with ANCA-associated vasculitis (AAV). METHODS: Peripheral blood from 36 patients with active AAV and 18 healthy controls was…
View details →Negative / Null Result ReportOpen accessMedicine
Matthias Diebold, Hannes Vietzen, Andreas Heinzel et al. · 2023 · American Journal of Transplantation
Antibody-mediated rejection (ABMR) is a leading cause of graft failure. Emerging evidence suggests a significant contribution of natural killer (NK) cells to microvascular inflammation (MVI). We investigated the influence of genetically determined NK cell functionality on ABMR development and activity. The study included 86 kidney transplant recipients subjected to systematic biopsies triggered by donor-specific antibody detection. We performed killer immunoglobulin-like receptor typing to predict missing self and genotyped polymorphisms determining NK cell functionality (FCGR3AV/F158 [rs39699
View details →Negative / Null Result ReportEngineering
Gardênia Marinho Cordeiro, M.F. Figueirêdo, Wagner Brandão Ramos et al. · 2017 · Industrial & Engineering Chemistry Research
Currently, process intensification using dividing-wall columns (DWCs) is one of the most promising alternatives for reducing the costs of the distillation process. However, for extractive distillation, there are still questions regarding…
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Yangmu Li, J. Terzic, P. G. Baity et al. · 2019 · Science Advances
The superconductivity in a stripe-ordered cuprate appears to change from 3- to 2- to 1-dimensional with increasing magnetic field.
View details →Negative / Null Result Report
Rafael Stern, Jonathan D Muller, Eyal Rotenberg et al. · 2023 · PNAS Nexus
Abstract Suppression of carbon emissions through photovoltaic (PV) energy and carbon sequestration through afforestation provides complementary climate change mitigation (CCM) strategies. However, a quantification of the “break-even time”…
View details →Negative / Null Result Report
Mélusine Boon-Falleur, Adrien Bouguen, Axelle Charpentier et al. · 2022 · Scientific Reports
Abstract Recent empirical research has shown that improving socio-emotional skills such as grit, conscientiousness and self-control leads to higher academic achievement and better life outcomes. However, both theoretical and empirical…
View details →Negative / Null Result Report
Levon Gabrielian, Luke W. Willshire, Stephen C. Helps et al. · 2011 · Journal of Neurotrauma
Traumatic brain injury (TBI) often causes raised intracranial pressure (ICP), with >50% of all TBI- related deaths being associated with this increase in ICP. To date, there is no effective pharmacological treatment for TBI, partly because…
View details →Negative / Null Result Report
Joana Paes de Faria, Nicoletta Kessaris, Paul Andrew et al. · 2014 · BMC Neuroscience
Abstract Background Olig1 and Olig2 , encoding closely related basic helix-loop-helix transcription factors, were originally identified in screens for glial-specific genes. Olig1 and Olig2 are both expressed in restricted parts of the…
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Jean-Philippe Hauzeur, Chantal Lechanteur, Etienne Baudoux et al. · 2019 · Clinical Orthopaedics & Related Research
Abstract Background In patients with nontraumatic osteonecrosis of the femoral head (ONFH), implantation of bone marrow aspirate concentrate (BMAC) could delay the progression of osteonecrosis and improve symptoms in pre-fracture ONFH.…
View details →Negative / Null Result Report
Sang Jun Song, Se Gu Kang, Yeon Je Lee et al. · 2018 · Knee Surgery, Sports Traumatology, Arthroscopy
Abstract Purpose In the present study, the early results of sensor‐assisted versus manually balanced posterior‐stabilized total knee arthroplasty (TKA) for osteoarthritis with varus deformities were prospectively compared. Methods Fifty…
View details →Negative / Null Result ReportPharmacology, Toxicology and Pharmaceutics
Anne‐Sophie Jannot, Xavier Vuillemin, Isabelle Étienne et al. · 2016 · Therapeutic Drug Monitoring
BACKGROUND: POR*28 is a recently newly described allelic variant of the cytochrome P450 oxidoreductase (POR), which might be associated with an increased metabolic activity of P450 cytochromes (CYP) 3A5 and 3A4. Consequently, carriers of…
View details →Negative / Null Result ReportSocial Sciences
Martin Merkt, Sabrina Lux, Vincent Hoogerheide et al. · 2019 · Journal of Educational Psychology
Two experiments investigated the effects of an instructional video's setting on learners' retention and application of the video content. Experiment 1 explored competing hypotheses based on theoretical assumptions about whether an…
View details →Negative / Null Result ReportOpen accessImmunology and Microbiology
Madeleine P. J. White, Chris Johnston, John R. Grainger et al. · 2020 · Frontiers in Immunology
Helminth parasites are effective in biasing Th2 immunity and inducing regulatory pathways that minimise excessive inflammation within their hosts, thus allowing chronic infection to occur whilst also suppressing bystander atopic or autoimmune diseases. Multiple sclerosis (MS) is a severe autoimmune disease characterised by inflammatory lesions within the central nervous system; there are very limited therapeutic options for the progressive forms of the disease and none are curative. Here, we used the experimental autoimmune encephalomyelitis (EAE) model to examine if the intestinal helminth He
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
W-J Xiao, J-W He, H Zhang et al. · 2010 · International Journal of Obesity
OBJECTIVE: Arachidonate 12-lipoxygenase (ALOX12) is a member of the lipoxygenase superfamily, which catalyzes the incorporation of molecular oxygen into polyunsaturated fatty acids. The products of ALOX12 reactions serve as endogenous…
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Zachary L. Pratt, Bingming Chen, Charles J. Czuprynski et al. · 2012 · Applied and Environmental Microbiology
Salmonella enterica forms aseptate filaments with multiple nucleoids when cultured in hyperosmotic conditions. These osmotic-induced filaments are viable and form single colonies on agar plates even though they contain multiple genomes and…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
I. Krzyzewska, Judith Ensink, Laura Nawijn et al. · 2018 · European Journal of Human Genetics
Posttraumatic stress disorder (PTSD) is a debilitating psychiatric disorder that may develop after a traumatic event. Here we aimed to identify epigenetic and genetic loci associated with PTSD. We included 73 traumatized police officers…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Mark P. Purdue, Yuanqing Ye, Zhaoming Wang et al. · 2013 · Cancer Epidemiology Biomarkers & Prevention
Genome-wide association studies (GWAS) of renal cell carcinoma (RCC) in populations of European ancestry have identified four susceptibility loci. No GWAS has been conducted among African Americans (AA), who experience a higher incidence…
View details →Negative / Null Result ReportOpen accessNeuroscience
Jack Dempsey, Qiawen Liu, Kiel Christianson · 2020 · Journal of Experimental Psychology Learning Memory and Cognition
Previous work has ostensibly shown that readers rapidly adapt to less predictable ambiguity resolutions after repeated exposure to unbalanced statistical input (e.g., a high number of reduced relative-clause garden-path sentences), and…
View details →Negative / Null Result ReportOpen accessPsychology
Aljoscha Rimpler, Henk A. L. Kiers, Don van Ravenzwaaij · 2025 · Behavior Research Methods
Interaction effects are very common in the psychological literature. However, interaction effects are typically very small and often fail to replicate. In this study, we conducted a simulation comparing the generalizability and estimability of two linear regression models: one correctly specified to account for interaction effects and one misspecified including simple effects only. We manipulated noise levels, predictor variable correlations, and different sets of regression weights, resulting in 9216 different conditions. From each dataset, we drew 1000 samples of N = 25, 50, 100, 250, 500, a
View details →Negative / Null Result ReportOpen accessMedicine
Hiroyuki Egami, Tomoya Matsumoto · 2020 · Sustainability
Lack of cash on hand is a significant obstacle in accessing healthcare services in developing countries. Many expectant mothers in the least developed countries do not receive sufficient care during pregnancy due to financial constraints. If such hurdles in accessing healthcare can be overcome, it will contribute to reduction in maternal and newborn mortality, which is a key target of Sustainable Development Goal 3. This study reports the first assessment of the impact of mobile money services on maternal care utilization. We hypothesize that mobile money adoption would motivate rural Ugandan
View details →Negative / Null Result ReportNeuroscience
Julia D. Hur, Loran F. Nordgren · 2016 · Journal of Personality and Social Psychology
The current research examines how exposure to performance incentives affects one's desire for the reward object. We hypothesized that the flexible nature of performance incentives creates an attentional fixation on the reward object (e.g.,…
View details →Negative / Null Result ReportNeuroscience
Mark Alfano · 2018 · PhilPapers (PhilPapers Foundation)
Virtues are dispositions that make their bearers admirable. Dispositions can be studied scientifically by systematically varying whether their alleged bearers are in (or take themselves to be in) the dispositions' eliciting conditions. In…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Rebecca C. Richmond, Carlos Sillero‐Rejon, Jasmine Khouja et al. · 2021 · Clinical Epigenetics
Abstract Background Little evidence exists on the health effects of e-cigarette use. DNA methylation may serve as a biomarker for exposure and could be predictive of future health risk. We aimed to investigate the DNA methylation profile of e-cigarette use. Results Among 117 smokers, 117 non-smokers and 116 non-smoking vapers, we evaluated associations between e-cigarette use and epigenome-wide methylation from saliva. DNA methylation at 7 cytosine-phosphate-guanine sites (CpGs) was associated with e-cigarette use at p < 1 × 10 –5 and none at p < 5.91 × 10 –8 . 13 CpGs were associated wi
View details →Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Jaehwan Park, Byungkwon Lim · 2018 · International Journal of Financial Studies
This paper explores the market efficiency of the six base metals traded on the LME (London Metal Exchange) using daily data from January 2000 to June 2016. The hypothesis that futures prices 3M (3-month) are unbiased predictors of spot prices (cash) in the LME is rejected based on the false premise that the financialization of commodities has been growing. For the robustness check, monthly data is analyzed using ordinary least squares (OLS) and GARCH (1,1) models. We reject the null hypothesis for all metals except for zinc.
View details →Negative / Null Result ReportOpen accessMedicine
Nina Bjerre Andersen, Lotte Dyhrberg O’Neill, Lise Kirstine Gormsen et al. · 2014 · BMC Medical Education
BACKGROUND: Reflection, the ability to examine critically one's own learning and functioning, is considered important for 'the good doctor'. The Groningen Reflection Ability Scale (GRAS) is an instrument measuring student reflection, which has not yet been validated beyond the original Dutch study. The aim of this study was to adapt GRAS for use in a Danish setting and to investigate the psychometric properties of GRAS-DK. METHODS: We performed a cross-cultural adaptation of GRAS from Dutch to Danish. Next, we collected primary data online, performed a retest, analysed data descriptively, esti
View details →Negative / Null Result ReportOpen accessPsychology
Robert Young, Daniel Vincent Riordan, Cameron Stark · 2011 · BMC Public Health
BACKGROUND: Past studies using large population based datasets link certain perinatal circumstances (birth weight, parity, etc) with mental health outcomes such as suicide, self-harm and psychiatric problems. Problematically, population datasets omit a number of social confounds. The aim of this study is to replicate past research linking perinatal circumstances and mental health (suicidality and use of psychiatric services) and to determine if such associations remain after adjusting for social circumstances. METHODS: A longitudinal school-based survey of 2157 young people (surveyed at age 11
View details →Negative / Null Result ReportOpen accessDecision Sciences
Mona Ghannad, Bada Yang, Mariska Leeflang et al. · 2020 · Journal of Clinical Epidemiology
OBJECTIVE: To estimate the effect of an intervention compared to the usual peer-review process on reducing spin in the abstract's conclusion of biomedical study reports. STUDY DESIGN AND SETTING: We conducted a two-arm, parallel-group RCT in a sample of primary research manuscripts submitted to BMJ Open. The authors received short instructions alongside the peer reviewers' comments in the intervention group. We assessed the presence of spin (primary outcome), types of spin, and wording change in the revised abstract's conclusion. Outcome assessors were blinded to the intervention assignment. R
View details →Negative / Null Result ReportOpen accessMedicine
Kyung‐No Son, Yong-kwan Kim, Jae‐Ku Oem et al. · 2017 · Transboundary and Emerging Diseases
Outbreaks of highly pathogenic avian influenza (HPAI) have been reported worldwide. Wild waterfowl play a major role in the maintenance and transmission of HPAI. Highly pathogenic avian influenza subtype H5N6 and H5N8 viruses simultaneously emerged in South Korea. In this study, the comparative pathogenicity and infectivity of Clade 2.3.4.4 Group B H5N8 and Group C H5N6 viruses were evaluated in Mandarin duck (Aix galericulata). None of the ducks infected with H5N6 or H5N8 viruses showed clinical signs or mortality. Serological assays revealed that the HA antigenicity of H5N8 and H5N6 viruses
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