A Lack of Significant Effect of POR*28 Allelic Variant on Tacrolimus Exposure in Kidney Transplant Recipients
Anne‐Sophie Jannot; Xavier Vuillemin; Isabelle Étienne; M. Büchler; Bruno Hurault de Ligny; Gabriel Choukroun; Charlotte Colosio; Antoine Thierry · 2016 · Therapeutic Drug Monitoring
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
BACKGROUND: POR*28 is a recently newly described allelic variant of the cytochrome P450 oxidoreductase (POR), which might be associated with an increased metabolic activity of P450 cytochromes (CYP) 3A5 and 3A4. Consequently, carriers of…
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Metadata source: OpenAlex · DOI 10.1097/ftd.0000000000000267